메뉴 건너뛰기




Volumn 10, Issue 1, 2011, Pages 57-67

Reviewing once more the c-myc and Ras collaboration: Converging at the cyclin D1-CDK4 complex and challenging basic concepts of cancer biology

Author keywords

c Myc; Cyclin D1; Immortalization; Oncogene; Transformation

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN BCL 2; RAS PROTEIN;

EID: 78650828153     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.1.14449     Document Type: Review
Times cited : (98)

References (194)
  • 1
    • 37249073366 scopus 로고    scopus 로고
    • Perspectives on c-myc, cyclin D1, and their interaction in cancer formation, progression, and response to chemotherapy
    • Liao D, Thakur A, Wu J, Biliran H, Sarkar FH. Perspectives on c-Myc, cyclin D1, and their interaction in cancer formation, progression and response to chemotherapy. Crit Rev Oncog 2007; 13:93-158. (Pubitemid 350274298)
    • (2007) Critical Reviews in Oncogenesis , vol.13 , Issue.2 , pp. 93-158
    • Liao, D.J.1    Thakur, A.2    Wu, J.3    Biliran, H.4    Sarkar, F.H.5
  • 3
    • 0035522894 scopus 로고    scopus 로고
    • Two genetic hits (more or less) to cancer
    • Knudson AG. Two genetic hits (more or less) to cancer. Nat Rev Cancer 2001; 1:157-62.
    • (2001) Nat Rev Cancer , vol.1 , pp. 157-162
    • Knudson, A.G.1
  • 4
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983; 304:596-602. (Pubitemid 13035496)
    • (1983) Nature , vol.304 , Issue.5927 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 5
    • 0023443072 scopus 로고
    • Immortalization by c-myc, H-ras and Ela oncogenes induces differential cellular gene expression and growth factor responses
    • Kelekar A, Cole MD. Immortalization by c-myc, H-ras and Ela oncogenes induces differential cellular gene expression and growth factor responses. Mol Cell Biol 1987; 7:3899-907.
    • (1987) Mol Cell Biol , vol.7 , pp. 3899-3907
    • Kelekar, A.1    Cole, M.D.2
  • 6
    • 0021178906 scopus 로고
    • Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture
    • Mougneau E, Lemieux L, Rassoulzadegan M, Cuzin F. Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture. Proc Natl Acad Sci USA 1984; 81:5758-62.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5758-5762
    • Mougneau, E.1    Lemieux, L.2    Rassoulzadegan, M.3    Cuzin, F.4
  • 7
    • 0035839650 scopus 로고    scopus 로고
    • c-Myc-mediated regulation of telomerase activity is disabled in immortalized cells
    • Drissi R, Zindy F, Roussel MF, Cleveland JL. c-Myc-mediated regulation of telomerase activity is disabled in immortalized cells. J Biol Chem 2001; 276:29994-30001.
    • (2001) J Biol Chem , vol.276 , pp. 29994-30001
    • Drissi, R.1    Zindy, F.2    Roussel, M.F.3    Cleveland, J.L.4
  • 9
    • 0023629979 scopus 로고
    • Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes
    • Kohl NE, Ruley HE. Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes. Oncogene 1987; 2:41-8.
    • (1987) Oncogene , vol.2 , pp. 41-48
    • Kohl, N.E.1    Ruley, H.E.2
  • 10
    • 0028034888 scopus 로고
    • Proliferative and metabolic capacity of rat embryo fibroblasts immortalized by c-myc depends on cellular age at oncogenic transfection
    • Simm A, Halle JP, Adam G. Proliferative and metabolic capacity of rat embryo fibroblasts immortalized by c-myc depends on cellular age at oncogenic transfection. Eur J Cell Biol 1994; 65:121-31.
    • (1994) Eur J Cell Biol , vol.65 , pp. 121-131
    • Simm, A.1    Halle, J.P.2    Adam, G.3
  • 11
    • 0027449156 scopus 로고
    • Deletion of the beta-turn/alpha-helix motif at the exon 2/3 boundary of human c-Myc leads to the loss of its immortalizing function
    • DOI 10.1016/0378-1119(93)90305-M
    • Zoidl G, Brockmann D, Esche H. Deletion of the beta-turn/alpha-helix motif at the exon 2/3 boundary of human c-Myc leads to the loss of its immortalizing function. Gene 1993; 131:269-74. (Pubitemid 223033429)
    • (1993) Gene , vol.131 , Issue.2 , pp. 269-274
    • Zoidl, G.1    Brockmann, D.2    Esche, H.3
  • 12
    • 36248992253 scopus 로고    scopus 로고
    • Epigenetic downregulation of ARF expression is a selection step in immortalization of human fibroblasts by c-Myc
    • Benanti JA, Wang ML, Myers HE, Robinson KL, Grandori C, Galloway DA. Epigenetic downregulation of ARF expression is a selection step in immortalization of human fibroblasts by c-Myc. Mol Cancer Res 2007; 5:1181-9.
    • (2007) Mol Cancer Res , vol.5 , pp. 1181-1189
    • Benanti, J.A.1    Wang, M.L.2    Myers, H.E.3    Robinson, K.L.4    Grandori, C.5    Galloway, D.A.6
  • 14
    • 62549151810 scopus 로고    scopus 로고
    • Implantation of c-mycER TAM immortalized human mesencephalic-derived clonal cell lines ameliorates behavior dysfunction in a rat model of Parkinson's disease
    • Miljan EA, Hines SJ, Pande P, Corteling RL, Hicks C, Zbarsky V, et al. Implantation of c-mycER TAM immortalized human mesencephalic-derived clonal cell lines ameliorates behavior dysfunction in a rat model of Parkinson's disease. Stem Cells Dev 2009; 18:307-19.
    • (2009) Stem Cells Dev , vol.18 , pp. 307-319
    • Miljan, E.A.1    Hines, S.J.2    Pande, P.3    Corteling, R.L.4    Hicks, C.5    Zbarsky, V.6
  • 15
    • 34748919514 scopus 로고    scopus 로고
    • A novel, immortal and multipotent human neural stem cell line generating functional neurons and oligodendrocytes
    • De Filippis L, Lamorte G, Snyder EY, Malgaroli A, Vescovi AL. A novel, immortal and multipotent human neural stem cell line generating functional neurons and oligodendrocytes. Stem Cells 2007; 25:2312-21.
    • (2007) Stem Cells , vol.25 , pp. 2312-2321
    • De Filippis, L.1    Lamorte, G.2    Snyder, E.Y.3    Malgaroli, A.4    Vescovi, A.L.5
  • 18
  • 19
    • 0036829333 scopus 로고    scopus 로고
    • Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells
    • Yaswen P, Stampfer MR. Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells. Int J Biochem Cell Biol 2002; 34:1382-94.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1382-1394
    • Yaswen, P.1    Stampfer, M.R.2
  • 21
    • 70350217758 scopus 로고    scopus 로고
    • Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes
    • Bazarov AV, Hines WC, Mukhopadhyay R, Beliveau A, Melodyev S, Zaslavsky Y, et al. Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes. Cell Cycle 2009; 8:3373-8.
    • (2009) Cell Cycle , vol.8 , pp. 3373-3378
    • Bazarov, A.V.1    Hines, W.C.2    Mukhopadhyay, R.3    Beliveau, A.4    Melodyev, S.5    Zaslavsky, Y.6
  • 22
    • 70349929533 scopus 로고    scopus 로고
    • c-Myc and telomerase activation
    • Dimri GP. c-Myc and telomerase activation. Cell Cycle 2009; 8:3075-6.
    • (2009) Cell Cycle , vol.8 , pp. 3075-3076
    • Dimri, G.P.1
  • 23
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams JM. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988; 335:440-2.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 24
    • 4344641255 scopus 로고    scopus 로고
    • Early work on the function of Bcl-2, an interview with David Vaux
    • Vaux DL. Early work on the function of Bcl-2, an interview with David Vaux. Cell Death Differ 2004; 11:28-32.
    • (2004) Cell Death Differ , vol.11 , pp. 28-32
    • Vaux, D.L.1
  • 25
    • 0023020262 scopus 로고
    • The myc oncogene: Its role in transformation and differentiation
    • Cole MD. The myc oncogene: its role in transformation and differentiation. Annu Rev Genet 1986; 20:361-84.
    • (1986) Annu Rev Genet , vol.20 , pp. 361-384
    • Cole, M.D.1
  • 26
    • 0021709745 scopus 로고
    • Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals
    • Keath EJ, Caimi PG, Cole MD. Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals. Cell 1984; 39:339-48.
    • (1984) Cell , vol.39 , pp. 339-348
    • Keath, E.J.1    Caimi, P.G.2    Cole, M.D.3
  • 27
    • 0022648072 scopus 로고
    • Tumorigenicity of fibroblast lines expressing the adenovirus E1a, cellular p53 or normal c-myc genes
    • Kelekar A, Cole MD. Tumorigenicity of fibroblast lines expressing the adenovirus E1a, cellular p53 or normal c-myc genes. Mol Cell Biol 1986; 6:7-14.
    • (1986) Mol Cell Biol , vol.6 , pp. 7-14
    • Kelekar, A.1    Cole, M.D.2
  • 29
    • 33750379861 scopus 로고    scopus 로고
    • Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis
    • Jang JW, Boxer RB, Chodosh LA. Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis. Mol Cell Biol 2006; 26:8109-21.
    • (2006) Mol Cell Biol , vol.26 , pp. 8109-8121
    • Jang, J.W.1    Boxer, R.B.2    Chodosh, L.A.3
  • 30
    • 0024383916 scopus 로고
    • Lymphomagenesis in E mu-myc transgenic mice can involve ras mutations
    • Alexander WS, Bernard O, Cory S, Adams JM. Lymphomagenesis in E mu-myc transgenic mice can involve ras mutations. Oncogene 1989; 4:575-81.
    • (1989) Oncogene , vol.4 , pp. 575-581
    • Alexander, W.S.1    Bernard, O.2    Cory, S.3    Adams, J.M.4
  • 31
    • 33748693361 scopus 로고    scopus 로고
    • Characterization of pancreatic lesions from MT-tgfalpha, Ela-myc and MT-tgfalpha/Elamyc single and double transgenic mice
    • Liao DJ, Wang Y, Wu J, Adsay NV, Grignon D, Khanani F. Characterization of pancreatic lesions from MT-tgfalpha, Ela-myc and MT-tgfalpha/Elamyc single and double transgenic mice. J Carcinog 2006; 5:1-19.
    • (2006) J Carcinog , vol.5 , pp. 1-19
    • Liao, D.J.1    Wang, Y.2    Wu, J.3    Adsay, N.V.4    Grignon, D.5    Khanani, F.6
  • 32
    • 0027965548 scopus 로고
    • Pancreatic carcinomas of acinar and mixed acinar/ductal phenotypes in Ela-1-myc transgenic mice do not contain c-K-ras mutations
    • Schaeffer BK, Terhune PG, Longnecker DS. Pancreatic carcinomas of acinar and mixed acinar/ductal phenotypes in Ela-1-myc transgenic mice do not contain c-K-ras mutations. Am J Pathol 1994; 145:696-701.
    • (1994) Am J Pathol , vol.145 , pp. 696-701
    • Schaeffer, B.K.1    Terhune, P.G.2    Longnecker, D.S.3
  • 33
    • 33751294627 scopus 로고    scopus 로고
    • Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras
    • Kim SH, Nakagawa H, Navaraj A, Naomoto Y, Klein-Szanto AJ, Rustgi AK, et al. Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras. Cancer Res 2006; 66:10415-24.
    • (2006) Cancer Res , vol.66 , pp. 10415-10424
    • Kim, S.H.1    Nakagawa, H.2    Navaraj, A.3    Naomoto, Y.4    Klein-Szanto, A.J.5    Rustgi, A.K.6
  • 34
    • 0344784889 scopus 로고    scopus 로고
    • Human mammary epithelial cell transformation through the activation of phosphatidylinositol-3-kinase
    • Zhao JJ, Gjoerup OV, Subramanian RR, Cheng Y, Chen W, Roberts TM, et al. Human mammary epithelial cell transformation through the activation of phosphatidylinositol-3-kinase. Cancer Cell 2003; 3:483-95.
    • (2003) Cancer Cell , vol.3 , pp. 483-495
    • Zhao, J.J.1    Gjoerup, O.V.2    Subramanian, R.R.3    Cheng, Y.4    Chen, W.5    Roberts, T.M.6
  • 35
    • 3042710564 scopus 로고    scopus 로고
    • Functional genetics and experimental models of human cancer
    • Zhao JJ, Roberts TM, Hahn WC. Functional genetics and experimental models of human cancer. Trends Mol Med 2004; 10:344-50.
    • (2004) Trends Mol Med , vol.10 , pp. 344-350
    • Zhao, J.J.1    Roberts, T.M.2    Hahn, W.C.3
  • 36
    • 34447530928 scopus 로고    scopus 로고
    • c-myc Transforms Human Mammary Epithelial Cells through Repression of the Wnt Inhibitors DKK1 and SFRP1
    • Cowling VH, D'Cruz CM, Chodosh LA, Cole MD. c-myc Transforms Human Mammary Epithelial Cells through Repression of the Wnt Inhibitors DKK1 and SFRP1. Mol Cell Biol 2007; 27:5135-46.
    • (2007) Mol Cell Biol , vol.27 , pp. 5135-5146
    • Cowling, V.H.1    D'Cruz, C.M.2    Chodosh, L.A.3    Cole, M.D.4
  • 39
    • 0021203313 scopus 로고
    • Malignant transformation of early passage rodent cells by a single mutated human oncogene
    • Spandidos DA, Wilkie NM. Malignant transformation of early passage rodent cells by a single mutated human oncogene. Nature 1984; 310:469-75.
    • (1984) Nature , vol.310 , pp. 469-475
    • Spandidos, D.A.1    Wilkie, N.M.2
  • 40
    • 0024458831 scopus 로고
    • Immortalization by truncated myc or ras genes and synergism between myc and ras genes in cell transformation
    • Spandidos DA, Lang JC. Immortalization by truncated myc or ras genes and synergism between myc and ras genes in cell transformation. Anticancer Res 1989; 9:1149-52.
    • (1989) Anticancer Res , vol.9 , pp. 1149-1152
    • Spandidos, D.A.1    Lang, J.C.2
  • 41
    • 0035177216 scopus 로고    scopus 로고
    • Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
    • Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, et al. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev 2001; 15:50-65.
    • (2001) Genes Dev , vol.15 , pp. 50-65
    • Elenbaas, B.1    Spirio, L.2    Koerner, F.3    Fleming, M.D.4    Zimonjic, D.B.5    Donaher, J.L.6
  • 42
    • 0036715018 scopus 로고    scopus 로고
    • Interactions between Ras1, dMyc and dPI3K signaling in the developing Drosophila wing
    • Prober DA, Edgar BA. Interactions between Ras1, dMyc and dPI3K signaling in the developing Drosophila wing. Genes Dev 2002; 16:2286-99.
    • (2002) Genes Dev , vol.16 , pp. 2286-2299
    • Prober, D.A.1    Edgar, B.A.2
  • 43
    • 0034306997 scopus 로고    scopus 로고
    • Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
    • Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev 2000; 14:2501-14.
    • (2000) Genes Dev , vol.14 , pp. 2501-2514
    • Sears, R.1    Nuckolls, F.2    Haura, E.3    Taya, Y.4    Tamai, K.5    Nevins, J.R.6
  • 44
    • 0035118130 scopus 로고    scopus 로고
    • A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation
    • Bazarov AV, Adachi S, Li SF, Mateyak MK, Wei S, Sedivy JM. A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation. Cancer Res 2001; 61:1178-86.
    • (2001) Cancer Res , vol.61 , pp. 1178-1186
    • Bazarov, A.V.1    Adachi, S.2    Li, S.F.3    Mateyak, M.K.4    Wei, S.5    Sedivy, J.M.6
  • 45
    • 33646892169 scopus 로고    scopus 로고
    • Genetically engineered human cancer models utilizing mammalian transgene expression
    • Kendall SD, Adam SJ, Counter CM. Genetically engineered human cancer models utilizing mammalian transgene expression. Cell Cycle 2006; 5:1074-9.
    • (2006) Cell Cycle , vol.5 , pp. 1074-1079
    • Kendall, S.D.1    Adam, S.J.2    Counter, C.M.3
  • 46
    • 27544453375 scopus 로고    scopus 로고
    • A network of genetic events sufficient to convert normal human cells to a tumorigenic state
    • Kendall SD, Linardic CM, Adam SJ, Counter CM. A network of genetic events sufficient to convert normal human cells to a tumorigenic state. Cancer Res 2005; 65:9824-8.
    • (2005) Cancer Res , vol.65 , pp. 9824-9828
    • Kendall, S.D.1    Linardic, C.M.2    Adam, S.J.3    Counter, C.M.4
  • 47
    • 62349118021 scopus 로고    scopus 로고
    • Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes
    • Sasaki R, Narisawa-Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, et al. Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes. Carcinogenesis 2009; 30:423-31.
    • (2009) Carcinogenesis , vol.30 , pp. 423-431
    • Sasaki, R.1    Narisawa-Saito, M.2    Yugawa, T.3    Fujita, M.4    Tashiro, H.5    Katabuchi, H.6
  • 48
    • 0037421484 scopus 로고    scopus 로고
    • NFkappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    • Dajee M, Lazarov M, Zhang JY, Cai T, Green CL, Russell AJ, et al. NFkappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature 2003; 421:639-43.
    • (2003) Nature , vol.421 , pp. 639-643
    • Dajee, M.1    Lazarov, M.2    Zhang, J.Y.3    Cai, T.4    Green, C.L.5    Russell, A.J.6
  • 49
    • 0037421888 scopus 로고    scopus 로고
    • Cancer: More than skin deep
    • Bolotin D, Fuchs E. Cancer: More than skin deep. Nature 2003; 421:594-5.
    • (2003) Nature , vol.421 , pp. 594-595
    • Bolotin, D.1    Fuchs, E.2
  • 51
    • 0037340013 scopus 로고    scopus 로고
    • Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells
    • Cheng G, Lewis AE, Meinkoth JL. Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells. Mol Endocrinol 2002; 17:450-9.
    • (2002) Mol Endocrinol , vol.17 , pp. 450-459
    • Cheng, G.1    Lewis, A.E.2    Meinkoth, J.L.3
  • 52
    • 0034725690 scopus 로고    scopus 로고
    • Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation
    • Shao J, Sheng H, DuBois RN, Beauchamp RD. Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation. J Biol Chem 2000; 275:22916-24.
    • (2000) J Biol Chem , vol.275 , pp. 22916-22924
    • Shao, J.1    Sheng, H.2    DuBois, R.N.3    Beauchamp, R.D.4
  • 53
    • 0034788574 scopus 로고    scopus 로고
    • Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism
    • Opitz OG, Suliman Y, Hahn WC, Harada H, Blum HE, Rustgi AK. Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism. J Clin Invest 2001; 108:725-32.
    • (2001) J Clin Invest , vol.108 , pp. 725-732
    • Opitz, O.G.1    Suliman, Y.2    Hahn, W.C.3    Harada, H.4    Blum, H.E.5    Rustgi, A.K.6
  • 54
    • 27344436091 scopus 로고    scopus 로고
    • Creating oral squamous cancer cells: A cellular model of oral-esophageal carcinogenesis
    • Goessel G, Quante M, Hahn WC, Harada H, Heeg S, Suliman Y, et al. Creating oral squamous cancer cells: a cellular model of oral-esophageal carcinogenesis. Proc Natl Acad Sci USA 2005; 102:15599-604.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15599-15604
    • Goessel, G.1    Quante, M.2    Hahn, W.C.3    Harada, H.4    Heeg, S.5    Suliman, Y.6
  • 55
    • 33645217263 scopus 로고    scopus 로고
    • EGFR signaling pathway in breast cancers: From traditional signal transduction to direct nuclear translocalization
    • Lo HW, Hsu SC, Hung MC. EGFR signaling pathway in breast cancers: From traditional signal transduction to direct nuclear translocalization. Breast Cancer Res Treat 2006; 95:211-8.
    • (2006) Breast Cancer Res Treat , vol.95 , pp. 211-218
    • Lo, H.W.1    Hsu, S.C.2    Hung, M.C.3
  • 58
    • 0034801952 scopus 로고    scopus 로고
    • Epidermal growth factor induces cyclin D1 in human pancreatic carcinoma: Evidence for a cyclin D1-dependent cell cycle progression
    • Poch B, Gansauge F, Schwarz A, Seufferlein T, Schnelldorfer T, Ramadani M, et al. Epidermal growth factor induces cyclin D1 in human pancreatic carcinoma: evidence for a cyclin D1-dependent cell cycle progression. Pancreas 2001; 23:280-7.
    • (2001) Pancreas , vol.23 , pp. 280-287
    • Poch, B.1    Gansauge, F.2    Schwarz, A.3    Seufferlein, T.4    Schnelldorfer, T.5    Ramadani, M.6
  • 59
    • 0029784950 scopus 로고    scopus 로고
    • Differential regulation of p27 and cyclin D1 by TGFbeta and EGF in C3H 10T1/2 mouse fibroblasts
    • Ravitz MJ, Yan S, Dolce C, Kinniburgh AJ, Wenner CE. Differential regulation of p27 and cyclin D1 by TGFbeta and EGF in C3H 10T1/2 mouse fibroblasts. J Cell Physiol 1996; 168:510-20.
    • (1996) J Cell Physiol , vol.168 , pp. 510-520
    • Ravitz, M.J.1    Yan, S.2    Dolce, C.3    Kinniburgh, A.J.4    Wenner, C.E.5
  • 60
    • 0029561285 scopus 로고
    • Mitogenic signal transduction in human breast cancer cells
    • Strobl JS, Wonderlin WF, Flynn DC. Mitogenic signal transduction in human breast cancer cells. Gen Pharmacol 1995; 26:1643-9.
    • (1995) Gen Pharmacol , vol.26 , pp. 1643-1649
    • Strobl, J.S.1    Wonderlin, W.F.2    Flynn, D.C.3
  • 61
    • 0030740210 scopus 로고    scopus 로고
    • kip1 downregulation, passage through the restriction point and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
    • kip1 downregulation, passage through the restriction point and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts. Mol Cell Biol 1997; 17:5348-58.
    • (1997) Mol Cell Biol , vol.17 , pp. 5348-5358
    • Takuwa, N.1    Takuwa, Y.2
  • 62
    • 22844445932 scopus 로고    scopus 로고
    • Use of human tissue to assess the oncogenic activity of melanoma-associated mutations
    • Chudnovsky Y, Adams AE, Robbins PB, Lin Q, Khavari PA. Use of human tissue to assess the oncogenic activity of melanoma-associated mutations. Nat Genet 2005; 37:745-9.
    • (2005) Nat Genet , vol.37 , pp. 745-749
    • Chudnovsky, Y.1    Adams, A.E.2    Robbins, P.B.3    Lin, Q.4    Khavari, P.A.5
  • 63
    • 18644382594 scopus 로고    scopus 로고
    • CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis
    • Lazarov M, Kubo Y, Cai T, Dajee M, Tarutani M, Lin Q, et al. CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis. Nat Med 2002; 8:1105-14.
    • (2002) Nat Med , vol.8 , pp. 1105-1114
    • Lazarov, M.1    Kubo, Y.2    Cai, T.3    Dajee, M.4    Tarutani, M.5    Lin, Q.6
  • 65
    • 0030567912 scopus 로고    scopus 로고
    • Role for Bcl-xL in the regulation of apoptosis by EGF and TGFbeta1 in c-myc overexpressing mammary epithelial cells
    • Nass SJ, Li M, Amundadottir LT, Furth PA, Dickson RB. Role for Bcl-xL in the regulation of apoptosis by EGF and TGFbeta1 in c-myc overexpressing mammary epithelial cells. Biochem Biophys Res Commun 1996; 227:248-56.
    • (1996) Biochem Biophys Res Commun , vol.227 , pp. 248-256
    • Nass, S.J.1    Li, M.2    Amundadottir, L.T.3    Furth, P.A.4    Dickson, R.B.5
  • 66
    • 0029135433 scopus 로고
    • The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice
    • Elson A, Deng C, Campos-Torres J, Donehower LA, Leder P. The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice. Oncogene 1995; 11:181-90.
    • (1995) Oncogene , vol.11 , pp. 181-190
    • Elson, A.1    Deng, C.2    Campos-Torres, J.3    Donehower, L.A.4    Leder, P.5
  • 67
    • 0032575089 scopus 로고    scopus 로고
    • Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability
    • McCormack SJ, Weaver Z, Deming S, Natarajan G, Torri J, Johnson MD, et al. Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability. Oncogene 1998; 16:2755-66.
    • (1998) Oncogene , vol.16 , pp. 2755-2766
    • McCormack, S.J.1    Weaver, Z.2    Deming, S.3    Natarajan, G.4    Torri, J.5    Johnson, M.D.6
  • 68
    • 67649352637 scopus 로고    scopus 로고
    • Nuclear cyclin D1: An oncogenic driver in human cancer
    • Kim JK, Diehl JA. Nuclear cyclin D1: an oncogenic driver in human cancer. J Cell Physiol 2009; 220:292-6.
    • (2009) J Cell Physiol , vol.220 , pp. 292-296
    • Kim, J.K.1    Diehl, J.A.2
  • 70
    • 63049084296 scopus 로고    scopus 로고
    • Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage dependence of cell growth and survival
    • Mori K, Hirao E, Toya Y, Oshima Y, Ishikawa F, Nose K, et al. Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage dependence of cell growth and survival. Mol Biol Cell 2009; 20:218-32.
    • (2009) Mol Biol Cell , vol.20 , pp. 218-232
    • Mori, K.1    Hirao, E.2    Toya, Y.3    Oshima, Y.4    Ishikawa, F.5    Nose, K.6
  • 71
    • 0030740215 scopus 로고    scopus 로고
    • Ectopic expression of cyclin D1 but not cyclin e induces anchorage- Independent cell cycle progression
    • Resnitzky D. Ectopic expression of cyclin D1 but not cyclin E induces anchorage-independent cell cycle progression. Mol Cell Biol 1997; 17:5640-7. (Pubitemid 27357660)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.9 , pp. 5640-5647
    • Resnitzky, D.1
  • 72
    • 30944440763 scopus 로고    scopus 로고
    • Cyclins: Roles in mitogenic signaling and oncogenic transformation
    • Musgrove EA. Cyclins: Roles in mitogenic signaling and oncogenic transformation. Growth Factors 2006; 24:13-9.
    • (2006) Growth Factors , vol.24 , pp. 13-19
    • Musgrove, E.A.1
  • 73
    • 34248595991 scopus 로고    scopus 로고
    • Synergistic effect of cyclin D1 and c-Myc leads to more aggressive and invasive mammary tumors in severe combined immunodeficient mice
    • Wang Y, Thakur A, Sun Y, Wu J, Biliran H, Bollig A, et al. Synergistic effect of cyclin D1 and c-Myc leads to more aggressive and invasive mammary tumors in severe combined immunodeficient mice. Cancer Res 2007; 67:3698-707.
    • (2007) Cancer Res , vol.67 , pp. 3698-3707
    • Wang, Y.1    Thakur, A.2    Sun, Y.3    Wu, J.4    Biliran, H.5    Bollig, A.6
  • 75
    • 27644431540 scopus 로고    scopus 로고
    • Ras and Myc can drive oncogenic cell proliferation through individual D-cyclins
    • Yu Q, Ciemerych MA, Sicinski P. Ras and Myc can drive oncogenic cell proliferation through individual D-cyclins. Oncogene 2005; 24:7114-9.
    • (2005) Oncogene , vol.24 , pp. 7114-7119
    • Yu, Q.1    Ciemerych, M.A.2    Sicinski, P.3
  • 76
    • 0033214080 scopus 로고    scopus 로고
    • Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27
    • Bouchard C, Thieke K, Maier A, Saffrich R, Hanley-Hyde J, Ansorge W, et al. Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27. EMBO J 1999; 18:5321-33.
    • (1999) EMBO J , vol.18 , pp. 5321-5333
    • Bouchard, C.1    Thieke, K.2    Maier, A.3    Saffrich, R.4    Hanley-Hyde, J.5    Ansorge, W.6
  • 77
    • 0035881691 scopus 로고    scopus 로고
    • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter
    • Bouchard C, Dittrich O, Kiermaier A, Dohmann K, Menkel A, Eilers M, et al. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev 2001; 15:2042-7.
    • (2001) Genes Dev , vol.15 , pp. 2042-2047
    • Bouchard, C.1    Dittrich, O.2    Kiermaier, A.3    Dohmann, K.4    Menkel, A.5    Eilers, M.6
  • 78
    • 0033214995 scopus 로고    scopus 로고
    • Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1)
    • Perez-Roger I, Kim SH, Griffiths B, Sewing A, Land H. Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). EMBO J 1999; 18:5310-20.
    • (1999) EMBO J , vol.18 , pp. 5310-5320
    • Perez-Roger, I.1    Kim, S.H.2    Griffiths, B.3    Sewing, A.4    Land, H.5
  • 80
    • 77956285633 scopus 로고    scopus 로고
    • Tipping the balance: Cdk2 enables Myc to suppress senescence
    • Hydbring P, Larsson LG. Tipping the balance: Cdk2 enables Myc to suppress senescence. Cancer Res 2010; 70:6687-91.
    • (2010) Cancer Res , vol.70 , pp. 6687-6691
    • Hydbring, P.1    Larsson, L.G.2
  • 81
    • 60949090561 scopus 로고    scopus 로고
    • Transcription of mRNA-type long non-coding RNAs (mlonRNAs) disrupts chromatin array
    • Hirota K, Ohta K. Transcription of mRNA-type long non-coding RNAs (mlonRNAs) disrupts chromatin array. Commun Integr Biol 2009; 2:25-6.
    • (2009) Commun Integr Biol , vol.2 , pp. 25-26
    • Hirota, K.1    Ohta, K.2
  • 83
    • 0030031213 scopus 로고    scopus 로고
    • Loss of Rb and Myc activation co-operate to suppress cyclin D1 and contribute to transformation
    • Marhin WW, Hei YJ, Chen S, Jiang Z, Gallie BL, Phillips RA, et al. Loss of Rb and Myc activation co-operate to suppress cyclin D1 and contribute to transformation. Oncogene 1996; 12:43-52.
    • (1996) Oncogene , vol.12 , pp. 43-52
    • Marhin, W.W.1    Hei, Y.J.2    Chen, S.3    Jiang, Z.4    Gallie, B.L.5    Phillips, R.A.6
  • 85
    • 76849084288 scopus 로고    scopus 로고
    • Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation
    • Cowling VH. Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation. Oncogene 2010; 29:930-6.
    • (2010) Oncogene , vol.29 , pp. 930-936
    • Cowling, V.H.1
  • 86
    • 0028868534 scopus 로고
    • Serum withdrawal induces apoptotic cell death in Ki-ras transformed but not in normal differentiated thyroid cells
    • di JB, Ulianich L, Racioppi L, D'Armiento F, Feliciello A, Pacifico F, et al. Serum withdrawal induces apoptotic cell death in Ki-ras transformed but not in normal differentiated thyroid cells. Biochem Biophys Res Commun 1995; 214:819-24.
    • (1995) Biochem Biophys Res Commun , vol.214 , pp. 819-824
    • Di, J.B.1    Ulianich, L.2    Racioppi, L.3    D'Armiento, F.4    Feliciello, A.5    Pacifico, F.6
  • 88
    • 0035504075 scopus 로고    scopus 로고
    • Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells
    • Cheng G, Meinkoth JL. Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells. Oncogene 2001; 20:7334-41.
    • (2001) Oncogene , vol.20 , pp. 7334-7341
    • Cheng, G.1    Meinkoth, J.L.2
  • 89
    • 0026568122 scopus 로고
    • Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras
    • Bond J, Dawson T, Lemoine N, Wynford-Thomas D. Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras. Mol Carcinog 1992; 5:129-35.
    • (1992) Mol Carcinog , vol.5 , pp. 129-135
    • Bond, J.1    Dawson, T.2    Lemoine, N.3    Wynford-Thomas, D.4
  • 91
    • 4444342240 scopus 로고    scopus 로고
    • Evidence for a cancer-specific switch at the CDK4 promoter with loss of control by both USF and c-Myc
    • Pawar SA, Szentirmay MN, Hermeking H, Sawadogo M. Evidence for a cancer-specific switch at the CDK4 promoter with loss of control by both USF and c-Myc. Oncogene 2004; 23:6125-35.
    • (2004) Oncogene , vol.23 , pp. 6125-6135
    • Pawar, S.A.1    Szentirmay, M.N.2    Hermeking, H.3    Sawadogo, M.4
  • 92
    • 0032996623 scopus 로고    scopus 로고
    • c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points
    • Mateyak MK, Obaya AJ, Sedivy JM. c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points. Mol Cell Biol 1999; 19:4672-83.
    • (1999) Mol Cell Biol , vol.19 , pp. 4672-4683
    • Mateyak, M.K.1    Obaya, A.J.2    Sedivy, J.M.3
  • 93
    • 0033551389 scopus 로고    scopus 로고
    • Mysterious liaisons: The relationship between c-Myc and the cell cycle
    • Obaya AJ, Mateyak MK, Sedivy JM. Mysterious liaisons: The relationship between c-Myc and the cell cycle. Oncogene 1999; 18:2934-41.
    • (1999) Oncogene , vol.18 , pp. 2934-2941
    • Obaya, A.J.1    Mateyak, M.K.2    Sedivy, J.M.3
  • 94
    • 0037163082 scopus 로고    scopus 로고
    • The proto-oncogene c-myc acts through the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) to facilitate the activation of Cdk4/6 and early G(1) phase progression
    • Obaya AJ, Kotenko I, Cole MD, Sedivy JM. The proto-oncogene c-myc acts through the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) to facilitate the activation of Cdk4/6 and early G(1) phase progression. J Biol Chem 2002; 277:31263-9.
    • (2002) J Biol Chem , vol.277 , pp. 31263-31269
    • Obaya, A.J.1    Kotenko, I.2    Cole, M.D.3    Sedivy, J.M.4
  • 96
    • 34447137342 scopus 로고    scopus 로고
    • Inhibition of CDK1 as a potential therapy for tumors overexpressing MYC
    • Goga A, Yang D, Tward AD, Morgan DO, Bishop JM. Inhibition of CDK1 as a potential therapy for tumors overexpressing MYC. Nat Med 2007; 13:820-7.
    • (2007) Nat Med , vol.13 , pp. 820-827
    • Goga, A.1    Yang, D.2    Tward, A.D.3    Morgan, D.O.4    Bishop, J.M.5
  • 97
    • 0023131856 scopus 로고
    • Activation of c-myc and c-K-ras oncogenes in primary rat tumors induced by ionizing radiation
    • Sawey MJ, Hood AT, Burns FJ, Garte SJ. Activation of c-myc and c-K-ras oncogenes in primary rat tumors induced by ionizing radiation. Mol Cell Biol 1987; 7:932-5.
    • (1987) Mol Cell Biol , vol.7 , pp. 932-935
    • Sawey, M.J.1    Hood, A.T.2    Burns, F.J.3    Garte, S.J.4
  • 98
    • 0021699564 scopus 로고
    • A novel combination of K-ras and myc amplification accompanied by point mutational activation of K-ras in a human lung cancer
    • Taya Y, Hosogai K, Hirohashi S, Shimosato Y, Tsuchiya R, Tsuchida N, et al. A novel combination of K-ras and myc amplification accompanied by point mutational activation of K-ras in a human lung cancer. EMBO J 1984; 3:2943-6.
    • (1984) EMBO J , vol.3 , pp. 2943-2946
    • Taya, Y.1    Hosogai, K.2    Hirohashi, S.3    Shimosato, Y.4    Tsuchiya, R.5    Tsuchida, N.6
  • 100
    • 37249020287 scopus 로고    scopus 로고
    • Mammary Carcinogenesis Is Preceded by Altered Epithelial Cell Turnover in Transforming Growth Factor-{alpha} and c-myc Transgenic Mice
    • Rose-Hellekant TA, Wentworth KM, Nikolai S, Kundel DW, Sandgren EP. Mammary Carcinogenesis Is Preceded by Altered Epithelial Cell Turnover in Transforming Growth Factor-{alpha} and c-myc Transgenic Mice. Am J Pathol 2006; 169:1821-32.
    • (2006) Am J Pathol , vol.169 , pp. 1821-1832
    • Rose-Hellekant, T.A.1    Wentworth, K.M.2    Nikolai, S.3    Kundel, D.W.4    Sandgren, E.P.5
  • 101
    • 13444292555 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatocarcinogenesis in transgenic mouse models of liver cancer
    • Calvisi DF, Thorgeirsson SS. Molecular mechanisms of hepatocarcinogenesis in transgenic mouse models of liver cancer. Toxicol Pathol 2005; 33:181-4.
    • (2005) Toxicol Pathol , vol.33 , pp. 181-184
    • Calvisi, D.F.1    Thorgeirsson, S.S.2
  • 102
    • 0030977321 scopus 로고    scopus 로고
    • Interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis
    • Thorgeirsson SS, Santoni-Rugiu E. Interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis. Mutat Res 1997; 376:221-34.
    • (1997) Mutat Res , vol.376 , pp. 221-234
    • Thorgeirsson, S.S.1    Santoni-Rugiu, E.2
  • 103
    • 0034653446 scopus 로고    scopus 로고
    • Transgenic mouse models in carcinogenesis research and testing
    • Thorgeirsson SS, Factor VM, Snyderwine EG. Transgenic mouse models in carcinogenesis research and testing. Toxicol Lett 2000; 112:553-5.
    • (2000) Toxicol Lett , vol.112 , pp. 553-555
    • Thorgeirsson, S.S.1    Factor, V.M.2    Snyderwine, E.G.3
  • 104
    • 34247465590 scopus 로고    scopus 로고
    • Histological complexities of pancreatic lesions from transgenic mouse models are consistent with biological and morphological heterogeneity of human pancreatic cancer
    • Liao JD, Adsay NV, Khannani F, Grignon D, Thakur A, Sarkar FH. Histological complexities of pancreatic lesions from transgenic mouse models are consistent with biological and morphological heterogeneity of human pancreatic cancer. Histol Histopathol 2007; 22:661-76.
    • (2007) Histol Histopathol , vol.22 , pp. 661-676
    • Liao, J.D.1    Adsay, N.V.2    Khannani, F.3    Grignon, D.4    Thakur, A.5    Sarkar, F.H.6
  • 105
    • 0031921230 scopus 로고    scopus 로고
    • Epidermal growth factor induces cyclin D1 in a human prostate cancer cell line
    • Perry JE, Grossmann ME, Tindall DJ. Epidermal growth factor induces cyclin D1 in a human prostate cancer cell line. Prostate 1998; 35:117-24.
    • (1998) Prostate , vol.35 , pp. 117-124
    • Perry, J.E.1    Grossmann, M.E.2    Tindall, D.J.3
  • 106
    • 0031438751 scopus 로고    scopus 로고
    • Transforming growth factor-alpha enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter
    • DOI 10.1074/jbc.272.52.33181
    • Yan YX, Nakagawa H, Lee MH, Rustgi AK. Transforming growth factor-alpha enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter. J Biol Chem 1997; 272:33181-90. (Pubitemid 28023664)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.52 , pp. 33181-33190
    • Yan, Y.-X.1    Nakagawa, H.2    Lee, M.-H.3    Rustgi, A.K.4
  • 107
    • 0034594963 scopus 로고    scopus 로고
    • Cell cycle basis for the onset and progression of c-Myc-induced, TGFalpha-enhanced mouse mammary gland carcinogenesis
    • Liao DJ, Natarajan G, Deming SL, Jamerson MH, Johnson M, Chepko G, et al. Cell cycle basis for the onset and progression of c-Myc-induced, TGFalpha-enhanced mouse mammary gland carcinogenesis. Oncogene 2000; 19:1307-17.
    • (2000) Oncogene , vol.19 , pp. 1307-1317
    • Liao, D.J.1    Natarajan, G.2    Deming, S.L.3    Jamerson, M.H.4    Johnson, M.5    Chepko, G.6
  • 108
    • 0029102871 scopus 로고
    • Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice
    • Sandgren EP, Schroeder JA, Qui TH, Palmiter RD, Brinster RL, Lee DC. Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. Cancer Res 1995; 55:3915-27.
    • (1995) Cancer Res , vol.55 , pp. 3915-3927
    • Sandgren, E.P.1    Schroeder, J.A.2    Qui, T.H.3    Palmiter, R.D.4    Brinster, R.L.5    Lee, D.C.6
  • 110
    • 0027976222 scopus 로고
    • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation
    • Lovec H, Sewing A, Lucibello FC, Muller R, Moroy T. Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene 1994; 9:323-6.
    • (1994) Oncogene , vol.9 , pp. 323-326
    • Lovec, H.1    Sewing, A.2    Lucibello, F.C.3    Muller, R.4    Moroy, T.5
  • 111
    • 0028274940 scopus 로고
    • Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene
    • Bodrug SE, Warner BJ, Bath ML, Lindeman GJ, Harris AW, Adams JM. Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. EMBO J 1994; 13:2124-30.
    • (1994) EMBO J , vol.13 , pp. 2124-2130
    • Bodrug, S.E.1    Warner, B.J.2    Bath, M.L.3    Lindeman, G.J.4    Harris, A.W.5    Adams, J.M.6
  • 112
    • 0028049592 scopus 로고
    • Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice
    • Lovec H, Grzeschiczek A, Kowalski MB, Moroy T. Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J 1994; 13:3487-95.
    • (1994) EMBO J , vol.13 , pp. 3487-3495
    • Lovec, H.1    Grzeschiczek, A.2    Kowalski, M.B.3    Moroy, T.4
  • 113
    • 67349202517 scopus 로고    scopus 로고
    • Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis
    • Kwek SS, Roy R, Zhou H, Climent J, Martinez-Climent JA, Fridlyand J, et al. Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis. Oncogene 2009; 28:1892-903.
    • (2009) Oncogene , vol.28 , pp. 1892-1903
    • Kwek, S.S.1    Roy, R.2    Zhou, H.3    Climent, J.4    Martinez-Climent, J.A.5    Fridlyand, J.6
  • 114
    • 0026068695 scopus 로고
    • c-myc reverses neu-induced transformed morphology by transcriptional repression
    • Suen TC, Hung MC. c-myc reverses neu-induced transformed morphology by transcriptional repression. Mol Cell Biol 1991; 11:354-62.
    • (1991) Mol Cell Biol , vol.11 , pp. 354-362
    • Suen, T.C.1    Hung, M.C.2
  • 115
    • 33744912772 scopus 로고    scopus 로고
    • The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis
    • DOI 10.1158/0008-5472.CAN-06-0037
    • Barsyte-Lovejoy D, Lau SK, Boutros PC, Khosravi F, Jurisica I, Andrulis IL, et al. The c-Myc oncogene directly induces the H19 noncoding RNA by allelespecific binding to potentiate tumorigenesis. Cancer Res 2006; 66:5330-7. (Pubitemid 43844958)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5330-5337
    • Barsyte-Lovejoy, D.1    Lau, S.K.2    Boutros, P.C.3    Khosravi, F.4    Jurisica, I.5    Andrulis, I.L.6    Tsao, M.S.7    Penn, L.Z.8
  • 116
    • 0033958518 scopus 로고    scopus 로고
    • C-Myc suppresses the tumorigenicity of lung cancer cells and down- Regulates vascular endothelial growth factor expression
    • Barr LF, Campbell SE, Diette GB, Gabrielson EW, Kim S, Shim H, et al. c-Myc suppresses the tumori-genicity of lung cancer cells and downregulates vascular endothelial growth factor expression. Cancer Res 2000; 60:143-9. (Pubitemid 30058744)
    • (2000) Cancer Research , vol.60 , Issue.1 , pp. 143-149
    • Barr, L.F.1    Campbell, S.E.2    Diette, G.B.3    Gabrielson, E.W.4    Kim, S.5    Shim, H.6    Dang, C.V.7
  • 117
    • 10944258521 scopus 로고    scopus 로고
    • Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation
    • DOI 10.1016/j.ccr.2004.10.013, PII S1535610804003071
    • Boxer RB, Jang JW, Sintasath L, Chodosh LA. Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation. Cancer Cell 2004; 6:577-86. (Pubitemid 40017701)
    • (2004) Cancer Cell , vol.6 , Issue.6 , pp. 577-586
    • Boxer, R.B.1    Jang, J.W.2    Sintasath, L.3    Chodosh, L.A.4
  • 119
    • 0038386618 scopus 로고    scopus 로고
    • Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence
    • Tilli MT, Furth PA. Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence. Breast Cancer Res 2003; 5:202-5.
    • (2003) Breast Cancer Res , vol.5 , pp. 202-205
    • Tilli, M.T.1    Furth, P.A.2
  • 120
    • 47749121455 scopus 로고    scopus 로고
    • Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas
    • Tran PT, Fan AC, Bendapudi PK, Koh S, Komatsubara K, Chen J, et al. Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas. PLoS One 2008; 3:2125.
    • (2008) PLoS One , vol.3 , pp. 2125
    • Tran, P.T.1    Fan, A.C.2    Bendapudi, P.K.3    Koh, S.4    Komatsubara, K.5    Chen, J.6
  • 121
    • 13844266564 scopus 로고    scopus 로고
    • Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis
    • DOI 10.1186/1741-7007-2-26
    • Pelengaris S, Abouna S, Cheung L, Ifandi V, Zervou S, Khan M. Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumors of pancreatic islets and skin epidermis. BMC Biol 2004; 2:26. (Pubitemid 40251682)
    • (2004) BMC Biology , vol.2 , pp. 26
    • Pelengaris, S.1    Abouna, S.2    Cheung, L.3    Ifandi, V.4    Zervou, S.5    Khan, M.6
  • 122
    • 0036798620 scopus 로고    scopus 로고
    • Marked intratumoral heterogeneity of c-myc and cyclinD1 but not of c-erbB2 amplification in breast cancer
    • Glockner S, Buurman H, Kleeberger W, Lehmann U, Kreipe H. Marked intratumoral heterogeneity of c-myc and cyclinD1 but not of c-erbB2 amplification in breast cancer. Lab Invest 2002; 82:1419-26. (Pubitemid 35191545)
    • (2002) Laboratory Investigation , vol.82 , Issue.10 , pp. 1419-1426
    • Glockner, S.1    Buurman, H.2    Kleeberger, W.3    Lehmann, U.4    Kreipe, H.5
  • 123
    • 0142043011 scopus 로고    scopus 로고
    • Cell death in MMTV-c-myc transgenic mouse mammary tumors may not be typical apoptosis
    • Liao DJ, Dickson RB. Cell death in MMTV-c-myc transgenic mouse mammary tumors may not be typical apoptosis. Lab Invest 2003; 83:1437-49.
    • (2003) Lab Invest , vol.83 , pp. 1437-1449
    • Liao, D.J.1    Dickson, R.B.2
  • 124
    • 23844490779 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line
    • DOI 10.1158/1078-0432.CCR-04-2419
    • Biliran H Jr, Wang Y, Banerjee S, Xu H, Heng H, Thakur A, et al. Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line. Clin Cancer Res 2005; 11:6075-86. (Pubitemid 41170340)
    • (2005) Clinical Cancer Research , vol.11 , Issue.16 , pp. 6075-6086
    • Biliran Jr., H.1    Wang, Y.2    Banerjee, S.3    Xu, H.4    Heng, H.5    Thakur, A.6    Bollig, A.7    Sarkar, F.H.8    Liao, J.D.9
  • 125
    • 34249028744 scopus 로고    scopus 로고
    • C-Myc-induced chemosensitization is mediated by suppression of cyclin D1 expression and nuclear factor-kappaB activity in pancreatic cancer cells
    • DOI 10.1158/1078-0432.CCR-06-1844
    • Biliran H Jr, Banerjee S, Thakur A, Xu H, Heng H, Thakur A, et al. c-Myc-induced chemosensitization is mediated by suppression of cyclin D1 expression and nuclear factor-kappaB activity in pancreatic cancer cells. Clin Cancer Res 2007; 13:2811-21. (Pubitemid 46788051)
    • (2007) Clinical Cancer Research , vol.13 , Issue.9 , pp. 2811-2821
    • Biliran Jr., H.1    Banerjee, S.2    Thakur, A.3    Sarkar, F.H.4    Bollig, A.5    Ahmed, F.6    Wu, J.7    Sun, Y.8    Liao, J.D.9
  • 126
    • 23844436971 scopus 로고    scopus 로고
    • Cyclin D1 and pancreatic carcinoma: A proliferative agonist and chemotherapeutic antagonist
    • Diehl JA, Benzeno S. Cyclin D1 and pancreatic carcinoma: a proliferative agonist and chemotherapeutic antagonist. Clin Cancer Res 2005; 11:5665-7.
    • (2005) Clin Cancer Res , vol.11 , pp. 5665-5667
    • Diehl, J.A.1    Benzeno, S.2
  • 127
    • 0032529165 scopus 로고    scopus 로고
    • Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
    • Robles AI, Rodriguez-Puebla ML, Glick AB, Trempus C, Hansen L, Sicinski P, et al. Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev 1998; 12:2469-74.
    • (1998) Genes Dev , vol.12 , pp. 2469-2474
    • Robles, A.I.1    Rodriguez-Puebla, M.L.2    Glick, A.B.3    Trempus, C.4    Hansen, L.5    Sicinski, P.6
  • 128
    • 0032909693 scopus 로고    scopus 로고
    • Ras activity and cyclin D1 expression: An essential mechanism of mouse skin tumor development
    • Rodriguez-Puebla ML, Robles AI, Conti CJ. ras activity and cyclin D1 expression: an essential mechanism of mouse skin tumor development. Mol Carcinog 1999; 24:1-6.
    • (1999) Mol Carcinog , vol.24 , pp. 1-6
    • Rodriguez-Puebla, M.L.1    Robles, A.I.2    Conti, C.J.3
  • 129
    • 0035963435 scopus 로고    scopus 로고
    • Specific protection against breast cancers by cyclin D1 ablation
    • Yu Q, Geng Y, Sicinski P. Specific protection against breast cancers by cyclin D1 ablation. Nature 2001; 411:1017-21.
    • (2001) Nature , vol.411 , pp. 1017-1021
    • Yu, Q.1    Geng, Y.2    Sicinski, P.3
  • 130
    • 0027494864 scopus 로고
    • Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression
    • Jiang W, Kahn SM, Zhou P, Zhang YJ, Cacace AM, Infante AS, et al. Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression. Oncogene 1993; 8:3447-57.
    • (1993) Oncogene , vol.8 , pp. 3447-3457
    • Jiang, W.1    Kahn, S.M.2    Zhou, P.3    Zhang, Y.J.4    Cacace, A.M.5    Infante, A.S.6
  • 131
    • 4444315057 scopus 로고    scopus 로고
    • Coexistence of BCL1/CCND1 and CMYC aberrations in blastoid mantle cell lymphoma: A rare finding associated with very poor outcome
    • DOI 10.1007/s00277-004-0879-2
    • Michaux L, Wlodarska I, Theate I, Stul M, Scheiff JM, Deneys V, et al. Coexistence of BCL1/CCND1 and CMYC aberrations in blastoid mantle cell lymphoma: a rare finding associated with very poor outcome. Ann Hematol 2004; 83:578-83. (Pubitemid 39209181)
    • (2004) Annals of Hematology , vol.83 , Issue.9 , pp. 578-583
    • Michaux, L.1    Wlodarska, I.2    Theate, I.3    Stul, M.4    Scheiff, J.-M.5    Deneys, V.6    Ferrant, A.7    Hagemeijer, A.8
  • 132
    • 0036837626 scopus 로고    scopus 로고
    • Beta-catenin mutations correlate with overexpression of C-myc and cyclin D1 Genes in bladder cancer
    • Shiina H, Igawa M, Shigeno K, Terashima M, Deguchi M, Yamanaka M, et al. Beta-catenin mutations correlate with overexpression of C-myc and cyclin D1 Genes in bladder cancer. J Urol 2002; 168:2220-6.
    • (2002) J Urol , vol.168 , pp. 2220-2226
    • Shiina, H.1    Igawa, M.2    Shigeno, K.3    Terashima, M.4    Deguchi, M.5    Yamanaka, M.6
  • 136
    • 0037376168 scopus 로고    scopus 로고
    • Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells
    • Stacey DW. Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells. Curr Opin Cell Biol 2003; 15:158-63.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 158-163
    • Stacey, D.W.1
  • 137
    • 69249230769 scopus 로고    scopus 로고
    • Mammalian cell cycle regulation: Several Cdks, numerous cyclins and diverse compensatory mechanisms
    • Satyanarayana A, Kaldis P. Mammalian cell cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 2009; 28:2925-39.
    • (2009) Oncogene , vol.28 , pp. 2925-2939
    • Satyanarayana, A.1    Kaldis, P.2
  • 139
    • 33746814985 scopus 로고    scopus 로고
    • Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function
    • Wang C, Li Z, Lu Y, Du R, Katiyar S, Yang J, et al. Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function. Proc Natl Acad Sci USA 2006; 103:11567-72.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11567-11572
    • Wang, C.1    Li, Z.2    Lu, Y.3    Du, R.4    Katiyar, S.5    Yang, J.6
  • 140
    • 77957966270 scopus 로고    scopus 로고
    • Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
    • Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, et al. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell 2010; 18:329-40.
    • (2010) Cancer Cell , vol.18 , pp. 329-340
    • Aggarwal, P.1    Vaites, L.P.2    Kim, J.K.3    Mellert, H.4    Gurung, B.5    Nakagawa, H.6
  • 141
    • 22844440952 scopus 로고    scopus 로고
    • Inhibition of Smad antiproliferative function by CDK phosphorylation
    • Liu F, Matsuura I. Inhibition of Smad antiproliferative function by CDK phosphorylation. Cell Cycle 2005; 4:63-6.
    • (2005) Cell Cycle , vol.4 , pp. 63-66
    • Liu, F.1    Matsuura, I.2
  • 142
    • 3142546336 scopus 로고    scopus 로고
    • Cyclin-dependent kinases regulate the antiproliferative function of Smads
    • Matsuura I, Denissova NG, Wang G, He D, Long J, Liu F. Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 2004; 430:226-31.
    • (2004) Nature , vol.430 , pp. 226-231
    • Matsuura, I.1    Denissova, N.G.2    Wang, G.3    He, D.4    Long, J.5    Liu, F.6
  • 143
    • 0037047269 scopus 로고    scopus 로고
    • Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors
    • Lin HM, Zhao L, Cheng SY. Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors. J Biol Chem 2002; 277:28733-41.
    • (2002) J Biol Chem , vol.277 , pp. 28733-28741
    • Lin, H.M.1    Zhao, L.2    Cheng, S.Y.3
  • 145
    • 23844491848 scopus 로고    scopus 로고
    • Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism
    • Fu M, Wang C, Rao M, Wu X, Bouras T, Zhang X, et al. Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism. J Biol Chem 2005; 280:29728-42.
    • (2005) J Biol Chem , vol.280 , pp. 29728-29742
    • Fu, M.1    Wang, C.2    Rao, M.3    Wu, X.4    Bouras, T.5    Zhang, X.6
  • 146
    • 0042971664 scopus 로고    scopus 로고
    • Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation
    • Wang C, Pattabiraman N, Zhou JN, Fu M, Sakamaki T, Albanese C, et al. Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation. Mol Cell Biol 2003; 23:6159-73.
    • (2003) Mol Cell Biol , vol.23 , pp. 6159-6173
    • Wang, C.1    Pattabiraman, N.2    Zhou, J.N.3    Fu, M.4    Sakamaki, T.5    Albanese, C.6
  • 147
    • 28544433465 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 4 expression is essential for neu-induced breast tumorigenesis
    • DOI 10.1158/0008-5472.CAN-05-2639
    • Reddy HK, Mettus RV, Rane SG, Grana X, Litvin J, Reddy EP. Cyclin-dependent kinase 4 expression is essential for neu-induced breast tumorigenesis. Cancer Res 2005; 65:10174-8. (Pubitemid 41743706)
    • (2005) Cancer Research , vol.65 , Issue.22 , pp. 10174-10178
    • Reddy, H.K.D.L.1    Mettus, R.V.2    Rane, S.G.3    Grana, X.4    Litvin, J.5    Reddy, E.P.6
  • 149
    • 0028063457 scopus 로고
    • Neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors
    • Morrison BW, Leder P. neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors. Oncogene 1994; 9:3417-26.
    • (1994) Oncogene , vol.9 , pp. 3417-3426
    • Morrison, B.W.1    Leder, P.2
  • 150
    • 36849033467 scopus 로고    scopus 로고
    • Turning the tables: Myc activates Wnt in breast cancer
    • Cowling VH, Cole MD. Turning the tables: Myc activates Wnt in breast cancer. Cell Cycle 2007; 6:2625-7.
    • (2007) Cell Cycle , vol.6 , pp. 2625-2627
    • Cowling, V.H.1    Cole, M.D.2
  • 151
    • 0033961809 scopus 로고    scopus 로고
    • Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway
    • Lee RJ, Albanese C, Fu M, D'Amico M, Lin B, Watanabe G, et al. Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway. Mol Cell Biol 2000; 20:672-83.
    • (2000) Mol Cell Biol , vol.20 , pp. 672-683
    • Lee, R.J.1    Albanese, C.2    Fu, M.3    D'Amico, M.4    Lin, B.5    Watanabe, G.6
  • 153
    • 30344479175 scopus 로고    scopus 로고
    • Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis
    • Landis MW, Pawlyk BS, Li T, Sicinski P, Hinds PW. Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis. Cancer Cell 2006; 9:13-22.
    • (2006) Cancer Cell , vol.9 , pp. 13-22
    • Landis, M.W.1    Pawlyk, B.S.2    Li, T.3    Sicinski, P.4    Hinds, P.W.5
  • 155
    • 0033531241 scopus 로고    scopus 로고
    • Functional domains in cyclin D1: PRb-kinase activity is not essential for transformation
    • Zwicker J, Brusselbach S, Jooss KU, Sewing A, Behn M, Lucibello FC, et al. Functional domains in cyclin D1: pRb-kinase activity is not essential for transformation. Oncogene 1999; 18:19-25.
    • (1999) Oncogene , vol.18 , pp. 19-25
    • Zwicker, J.1    Brusselbach, S.2    Jooss, K.U.3    Sewing, A.4    Behn, M.5    Lucibello, F.C.6
  • 156
  • 157
    • 42449087261 scopus 로고    scopus 로고
    • Switching cyclin D-Cdk4 kinase activity on and off
    • Blain SW. Switching cyclin D-Cdk4 kinase activity on and off. Cell Cycle 2008; 7:892-8.
    • (2008) Cell Cycle , vol.7 , pp. 892-898
    • Blain, S.W.1
  • 159
    • 29244480619 scopus 로고    scopus 로고
    • Cytoplasmic sequestration of cyclin D1 associated with cell cycle withdrawal of neuroblastoma cells
    • DOI 10.1016/j.bbrc.2005.11.181, PII S0006291X05027269
    • Sumrejkanchanakij P, Eto K, Ikeda MA. Cytoplasmic sequestration of cyclin D1 associated with cell cycle withdrawal of neuroblastoma cells. Biochem Biophys Res Commun 2006; 340:302-8. (Pubitemid 41827681)
    • (2006) Biochemical and Biophysical Research Communications , vol.340 , Issue.1 , pp. 302-308
    • Sumrejkanchanakij, P.1    Eto, K.2    Ikeda, M.-A.3
  • 160
    • 0033379842 scopus 로고    scopus 로고
    • Regulation of G(1) cyclin-dependent kinases in the liver: Role of nuclear localization and p27 sequestration
    • Albrecht JH, Rieland BM, Nelsen CJ, Ahonen CL. Regulation of G(1) cyclin-dependent kinases in the liver: role of nuclear localization and p27 sequestration. Am J Physiol 1999; 277:1207-16.
    • (1999) Am J Physiol , vol.277 , pp. 1207-1216
    • Albrecht, J.H.1    Rieland, B.M.2    Nelsen, C.J.3    Ahonen, C.L.4
  • 161
    • 0036235954 scopus 로고    scopus 로고
    • Removal of Cdk inhibitors through both sequestration and downregulation in zearalenone-treated MCF-7 breast cancer cells
    • Ahamed S, Foster JS, Bukovsky A, Diehl JA, Wimalasena J. Removal of Cdk inhibitors through both sequestration and downregulation in zearalenone-treated MCF-7 breast cancer cells. Mol Carcinog 2002; 34:45-58.
    • (2002) Mol Carcinog , vol.34 , pp. 45-58
    • Ahamed, S.1    Foster, J.S.2    Bukovsky, A.3    Diehl, J.A.4    Wimalasena, J.5
  • 163
    • 34247149015 scopus 로고    scopus 로고
    • The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention
    • Alao JP. The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention. Mol Cancer 2007; 6:24.
    • (2007) Mol Cancer , vol.6 , pp. 24
    • Alao, J.P.1
  • 164
    • 10444285015 scopus 로고    scopus 로고
    • Evaluation of cyclin D1 expression and its subcellular distribution in mouse tissues
    • De FM, Fedele V, De LL, Penta R, Cottone G, Cavallotti I, et al. Evaluation of cyclin D1 expression and its subcellular distribution in mouse tissues. J Anat 2004; 205:405-12.
    • (2004) J Anat , vol.205 , pp. 405-412
    • De, F.M.1    Fedele, V.2    De, L.L.3    Penta, R.4    Cottone, G.5    Cavallotti, I.6
  • 166
    • 0033559264 scopus 로고    scopus 로고
    • The p21(Cip1) and p27(Kip1) CDK "inhibitors" are essential activators of cyclin D-dependent kinases in murine fibroblasts
    • Cheng M, Olivier P, Diehl JA, Fero M, Roussel MF, Roberts JM, et al. The p21(Cip1) and p27(Kip1) CDK "inhibitors" are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J 1999; 18:1571-83.
    • (1999) EMBO J , vol.18 , pp. 1571-1583
    • Cheng, M.1    Olivier, P.2    Diehl, J.A.3    Fero, M.4    Roussel, M.F.5    Roberts, J.M.6
  • 168
    • 0016318441 scopus 로고
    • Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium
    • Freedman VH, Shin SI. Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell 1974; 3:355-9.
    • (1974) Cell , vol.3 , pp. 355-359
    • Freedman, V.H.1    Shin, S.I.2
  • 169
    • 0034458577 scopus 로고    scopus 로고
    • Xenograft models of premalignant breast disease
    • Miller FR. Xenograft models of premalignant breast disease. J Mammary Gland Biol Neoplasia 2000; 5:379-91.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 379-391
    • Miller, F.R.1
  • 170
    • 77950114803 scopus 로고    scopus 로고
    • Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines
    • Kadota M, Yang HH, Gomez B, Sato M, Clifford RJ, Meerzaman D, et al. Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines. PLoS One 2010; 5:9201.
    • (2010) PLoS One , vol.5 , pp. 9201
    • Kadota, M.1    Yang, H.H.2    Gomez, B.3    Sato, M.4    Clifford, R.J.5    Meerzaman, D.6
  • 172
    • 52949088321 scopus 로고    scopus 로고
    • Leaving home early: Reexamination of the canonical models of tumor progression
    • Weinberg RA. Leaving home early: reexamination of the canonical models of tumor progression. Cancer Cell 2008; 14:283-4.
    • (2008) Cancer Cell , vol.14 , pp. 283-284
    • Weinberg, R.A.1
  • 175
    • 0026729695 scopus 로고
    • Multistage carcinogenesis in mouse skin
    • DiGiovanni J. Multistage carcinogenesis in mouse skin. Pharmacol Ther 1992; 54:63-128.
    • (1992) Pharmacol Ther , vol.54 , pp. 63-128
    • DiGiovanni, J.1
  • 176
    • 0019829342 scopus 로고
    • Mechanisms of chemical carcinogenesis
    • Miller EC, Miller JA. Mechanisms of chemical carcinogenesis. Cancer 1981; 47:1055-64.
    • (1981) Cancer , vol.47 , pp. 1055-1064
    • Miller, E.C.1    Miller, J.A.2
  • 177
    • 0020789191 scopus 로고
    • Hormone-dependent mammary tumors in mice and rats as a model for human breast cancer (review)
    • Briand P. Hormone-dependent mammary tumors in mice and rats as a model for human breast cancer (review). Anticancer Res 1983; 3:273-81.
    • (1983) Anticancer Res , vol.3 , pp. 273-281
    • Briand, P.1
  • 178
    • 0013857665 scopus 로고
    • Estrogen-induced breast cancer in the rat
    • Cutts JH. Estrogen-induced breast cancer in the rat. Proc Can Cancer Conf 1966; 6:50-68.
    • (1966) Proc Can Cancer Conf , vol.6 , pp. 50-68
    • Cutts, J.H.1
  • 179
    • 0023110431 scopus 로고
    • Laboratory models of breast cancer to aid the elucidation of antiestrogen action
    • Jordan VC. Laboratory models of breast cancer to aid the elucidation of antiestrogen action. J Lab Clin Med 1987; 109:267-77.
    • (1987) J Lab Clin Med , vol.109 , pp. 267-277
    • Jordan, V.C.1
  • 180
    • 0036126095 scopus 로고    scopus 로고
    • Roles of androgens in the development, growth and carcinogenesis of the mammary gland
    • Liao DJ, Dickson RB. Roles of androgens in the development, growth and carcinogenesis of the mammary gland. J Steroid Biochem Mol Biol 2002; 80:175-89.
    • (2002) J Steroid Biochem Mol Biol , vol.80 , pp. 175-189
    • Liao, D.J.1    Dickson, R.B.2
  • 182
    • 0013641814 scopus 로고
    • Mammary tumors of the rat: A review
    • Noble RL, Cutts JH. Mammary tumors of the rat: a review. Cancer Res 1959; 19:1125-39.
    • (1959) Cancer Res , vol.19 , pp. 1125-1139
    • Noble, R.L.1    Cutts, J.H.2
  • 183
    • 0020336540 scopus 로고
    • Prostate carcinoma of the Nb rat in relation to hormones
    • Noble RL. Prostate carcinoma of the Nb rat in relation to hormones. Int Rev Exp Pathol 1982; 23:113-59.
    • (1982) Int Rev Exp Pathol , vol.23 , pp. 113-159
    • Noble, R.L.1
  • 184
    • 0015799154 scopus 로고
    • Enzyme activities in regressing estrone-induced mammary tumors of the rat
    • Cutts JH. Enzyme activities in regressing estrone-induced mammary tumors of the rat. Cancer Res 1973; 33:1235-7.
    • (1973) Cancer Res , vol.33 , pp. 1235-1237
    • Cutts, J.H.1
  • 185
    • 0014368026 scopus 로고
    • Regression of estrone-induced mammary tumors in the rat
    • Cutts JH, Froude GC. Regression of estrone-induced mammary tumors in the rat. Cancer Res 1968; 28:2413-8.
    • (1968) Cancer Res , vol.28 , pp. 2413-2418
    • Cutts, J.H.1    Froude, G.C.2
  • 186
    • 0018192033 scopus 로고
    • Endocrine-induced regression of cancers
    • Huggins C. Endocrine-induced regression of cancers. Am J Surg 1978; 136:233-8.
    • (1978) Am J Surg , vol.136 , pp. 233-238
    • Huggins, C.1
  • 187
    • 0015296594 scopus 로고
    • Regression of stem-cell erythroblastic leukemia after hypophysectomy
    • Huggins C, Oka H. Regression of stem-cell erythroblastic leukemia after hypophysectomy. Cancer Res 1972; 32:239-42.
    • (1972) Cancer Res , vol.32 , pp. 239-242
    • Huggins, C.1    Oka, H.2
  • 188
    • 0021352953 scopus 로고
    • Regression of myelocytic leukemia in rats after hypophysectomy
    • Huggins CB, Ueda N. Regression of myelocytic leukemia in rats after hypophysectomy. Proc Natl Acad Sci USA 1984; 81:598-601.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 598-601
    • Huggins, C.B.1    Ueda, N.2
  • 189
    • 0014151337 scopus 로고
    • Endocrine-induced regression of cancers
    • Huggins C. Endocrine-induced regression of cancers. Cancer Res 1967; 27:1925-30.
    • (1967) Cancer Res , vol.27 , pp. 1925-1930
    • Huggins, C.1
  • 190
    • 0022516374 scopus 로고
    • Conversion of malignant cells into normal ones
    • Shvemberger IN. Conversion of malignant cells into normal ones. Int Rev Cytol 1986; 103:341-86.
    • (1986) Int Rev Cytol , vol.103 , pp. 341-386
    • Shvemberger, I.N.1
  • 191
    • 52049122139 scopus 로고    scopus 로고
    • Tumor dormancy and oncogene addiction
    • Felsher DW. Tumor dormancy and oncogene addiction. APMIS 2008; 116:629-37.
    • (2008) APMIS , vol.116 , pp. 629-637
    • Felsher, D.W.1
  • 192
    • 33750624190 scopus 로고    scopus 로고
    • Oncogene-blocking therapies: New insights from conditional mouse tumor models
    • Hengstler JG, Bockamp EO, Hermes M, et al. Oncogene-blocking therapies: new insights from conditional mouse tumor models. Curr Cancer Drug Targets 2006; 6:603-12.
    • (2006) Curr Cancer Drug Targets , vol.6 , pp. 603-612
    • Hengstler, J.G.1    Bockamp, E.O.2    Hermes, M.3
  • 193
    • 33748934199 scopus 로고    scopus 로고
    • Tumor dormancy: Death and resurrection of cancer as seen through transgenic mouse models
    • Felsher DW. Tumor dormancy: death and resurrection of cancer as seen through transgenic mouse models. Cell Cycle 2006; 5:1808-11.
    • (2006) Cell Cycle , vol.5 , pp. 1808-1811
    • Felsher, D.W.1
  • 194
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 2007; 7:834-46.
    • (2007) Nat Rev Cancer , vol.7 , pp. 834-846
    • Aguirre-Ghiso, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.