-
1
-
-
28644449614
-
Frequent overexpression of epidermal growth factor receptor (EGFR) in mammary high grade ductal carcinomas with myoepithelial differentiation
-
Shien T, Tashiro T, Omatsu M, et al. Frequent overexpression of epidermal growth factor receptor (EGFR) in mammary high grade ductal carcinomas with myoepithelial differentiation. J Clin Pathol 2005;58:1299-304.
-
(2005)
J Clin Pathol
, vol.58
, pp. 1299-1304
-
-
Shien, T.1
Tashiro, T.2
Omatsu, M.3
-
2
-
-
33644873490
-
Overexpression of platelet-derived growth factor receptor α in breast cancer is associated with tumour progression
-
Carvalho I, Milanezi F, Martins A, Reis RM, Schmitt F. Overexpression of platelet-derived growth factor receptor α in breast cancer is associated with tumour progression. Breast Cancer Res 2005;7:R788-95.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Carvalho, I.1
Milanezi, F.2
Martins, A.3
Reis, R.M.4
Schmitt, F.5
-
3
-
-
17144412880
-
Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas
-
Born M, Quintanilla-Fend L, Braselmann H, et al. Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas. J Pathol 2005;205:592-6.
-
(2005)
J Pathol
, vol.205
, pp. 592-596
-
-
Born, M.1
Quintanilla-Fend, L.2
Braselmann, H.3
-
4
-
-
0024546195
-
Tyrosine kinase activity in breast cancer, benign breast disease, and normal breast tissue
-
Hennipman A, van Oirschot BA, Smits J, Rijksen G, Staal GE. Tyrosine kinase activity in breast cancer, benign breast disease, and normal breast tissue. Cancer Res 1989;49:516-21.
-
(1989)
Cancer Res
, vol.49
, pp. 516-521
-
-
Hennipman, A.1
van Oirschot, B.A.2
Smits, J.3
Rijksen, G.4
Staal, G.E.5
-
5
-
-
0035158293
-
Expression of acidic fibroblast growth factor (aFGF) and fibroblast growth factor receptor 4 (FGFR4) in breast fibroadenomas
-
La Rosa S, Sessa F, Colombo L, Tibiletti MG, Furlan D, Capella C. Expression of acidic fibroblast growth factor (aFGF) and fibroblast growth factor receptor 4 (FGFR4) in breast fibroadenomas. J Clin Pathol 2001;54:37-41.
-
(2001)
J Clin Pathol
, vol.54
, pp. 37-41
-
-
La Rosa, S.1
Sessa, F.2
Colombo, L.3
Tibiletti, M.G.4
Furlan, D.5
Capella, C.6
-
6
-
-
3042552362
-
HER-2 gene amplification can be acquired as breast cancer progresses
-
Meng S, Tripathy D, Shete S, et al. HER-2 gene amplification can be acquired as breast cancer progresses. Proc Natl Acad Sci U S A 2004;101:9393-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9393-9398
-
-
Meng, S.1
Tripathy, D.2
Shete, S.3
-
7
-
-
10944249457
-
Expression of insulin-like growth factor 1 receptor in primary breast cancer: Immunohistochemical analysis
-
Shimizu C, Hasegawa T, Tani Y, et al. Expression of insulin-like growth factor 1 receptor in primary breast cancer: immunohistochemical analysis. Hum Pathol 2004;35:1537-42.
-
(2004)
Hum Pathol
, vol.35
, pp. 1537-1542
-
-
Shimizu, C.1
Hasegawa, T.2
Tani, Y.3
-
8
-
-
7344241591
-
Overexpression of the RON gene in human breast carcinoma
-
Maggiora P, Marchio S, Stella MC, et al. Overexpression of the RON gene in human breast carcinoma. Oncogene 1998;16:2927-33.
-
(1998)
Oncogene
, vol.16
, pp. 2927-2933
-
-
Maggiora, P.1
Marchio, S.2
Stella, M.C.3
-
9
-
-
16844363750
-
Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients
-
Lee WY, Chen HH, Chow NH, Su WC, Lin PW, Guo HR. Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients. Clin Cancer Res 2005;11:2222-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2222-2228
-
-
Lee, W.Y.1
Chen, H.H.2
Chow, N.H.3
Su, W.C.4
Lin, P.W.5
Guo, H.R.6
-
10
-
-
0029959639
-
-
Iwama A, Yamaguchi N, Suda T. STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family. EMBO J 1996;15:5866-75.
-
Iwama A, Yamaguchi N, Suda T. STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family. EMBO J 1996;15:5866-75.
-
-
-
-
11
-
-
0034685025
-
Requirement of both tyrosine residues 1330 and 1337 in the C-terminal tail of the RON receptor tyrosine kinase for epithelial cell scattering and migration
-
Xiao ZQ, Chen YQ, Wang MH. Requirement of both tyrosine residues 1330 and 1337 in the C-terminal tail of the RON receptor tyrosine kinase for epithelial cell scattering and migration. Biochem Biophys Res Commun 2000;267:669-75.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 669-675
-
-
Xiao, Z.Q.1
Chen, Y.Q.2
Wang, M.H.3
-
12
-
-
0031975738
-
The role of β-catenin in cell adhesion, signal transduction, and cancer
-
Bullions LC, Levine AJ. The role of β-catenin in cell adhesion, signal transduction, and cancer. Curr Opin Oncol 1998;10:81-7.
-
(1998)
Curr Opin Oncol
, vol.10
, pp. 81-87
-
-
Bullions, L.C.1
Levine, A.J.2
-
13
-
-
0029997180
-
Constitutive activation of the RON gene promotes invasive growth but not transformation
-
Santoro MM, Collesi C, Grisendi S, Gaudino G, Comoglio PM. Constitutive activation of the RON gene promotes invasive growth but not transformation. Mol Cell Biol 1996;16:7072-83.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 7072-7083
-
-
Santoro, M.M.1
Collesi, C.2
Grisendi, S.3
Gaudino, G.4
Comoglio, P.M.5
-
14
-
-
0029838319
-
Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein
-
Wang MH, Montero-Julian FA, Dauny I, Leonard EJ. Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein. Oncogene 1996;13:2167-75.
-
(1996)
Oncogene
, vol.13
, pp. 2167-2175
-
-
Wang, M.H.1
Montero-Julian, F.A.2
Dauny, I.3
Leonard, E.J.4
-
15
-
-
0033060256
-
Induction of cell shape changes through activation of the interleukin-3 common β chain receptor by the RON receptor-type tyrosine kinase
-
Mera A, Suga M, Ando M, Suda T, Yamaguchi N. Induction of cell shape changes through activation of the interleukin-3 common β chain receptor by the RON receptor-type tyrosine kinase. J Biol Chem 1999;274:15766-74.
-
(1999)
J Biol Chem
, vol.274
, pp. 15766-15774
-
-
Mera, A.1
Suga, M.2
Ando, M.3
Suda, T.4
Yamaguchi, N.5
-
16
-
-
0030774077
-
Functional characterization of domains contained in hepatocyte growth factor-like protein
-
Waltz SE, McDowell SA, Muraoka RS, et al. Functional characterization of domains contained in hepatocyte growth factor-like protein. J Biol Chem 1997;272:30526-37.
-
(1997)
J Biol Chem
, vol.272
, pp. 30526-30537
-
-
Waltz, S.E.1
McDowell, S.A.2
Muraoka, R.S.3
-
17
-
-
0034908762
-
Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the β-catenin pathway
-
Danilkovitch-Miagkova A, Miagkov A, Skeel A, Nakaigawa N, Zbar B, Leonard EJ. Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the β-catenin pathway. Mol Cell Biol 2001;21:5857-68.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5857-5868
-
-
Danilkovitch-Miagkova, A.1
Miagkov, A.2
Skeel, A.3
Nakaigawa, N.4
Zbar, B.5
Leonard, E.J.6
-
18
-
-
0032522486
-
Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene
-
Schmidt L, Junker K, Weirich G, et al. Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene. Cancer Res 1998;58:1719-22.
-
(1998)
Cancer Res
, vol.58
, pp. 1719-1722
-
-
Schmidt, L.1
Junker, K.2
Weirich, G.3
-
19
-
-
0035959871
-
Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis
-
Peace BE, Hughes MJ, Degen SJ, Waltz SE. Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis. Oncogene 2001;20:6142-51.
-
(2001)
Oncogene
, vol.20
, pp. 6142-6151
-
-
Peace, B.E.1
Hughes, M.J.2
Degen, S.J.3
Waltz, S.E.4
-
20
-
-
0032514371
-
Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor
-
Santoro MM, Penengo L, Minetto M, Orecchia S, Cilli M, Gaudino G. Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor. Oncogene 1998;17:741-9.
-
(1998)
Oncogene
, vol.17
, pp. 741-749
-
-
Santoro, M.M.1
Penengo, L.2
Minetto, M.3
Orecchia, S.4
Cilli, M.5
Gaudino, G.6
-
21
-
-
0028206124
-
Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells
-
Iwama A, Okano K, Sudo T, Matsuda Y, Suda T. Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells. Blood 1994;83:3160-9.
-
(1994)
Blood
, vol.83
, pp. 3160-3169
-
-
Iwama, A.1
Okano, K.2
Sudo, T.3
Matsuda, Y.4
Suda, T.5
-
22
-
-
0032495551
-
Characterization of the mouse Ron/Stk receptor tyrosine kinase gene
-
Waltz SE, Toms CL, McDowell SA, et al. Characterization of the mouse Ron/Stk receptor tyrosine kinase gene. Oncogene 1998;16:27-42.
-
(1998)
Oncogene
, vol.16
, pp. 27-42
-
-
Waltz, S.E.1
Toms, C.L.2
McDowell, S.A.3
-
23
-
-
0034658479
-
Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor
-
Omer CA, Chen Z, Diehl RE, et al. Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor. Cancer Res 2000;60:2680-8.
-
(2000)
Cancer Res
, vol.60
, pp. 2680-2688
-
-
Omer, C.A.1
Chen, Z.2
Diehl, R.E.3
-
24
-
-
0028174024
-
A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
-
Hofstra RM, Landsvater RM, Ceccherini I, et al. A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature 1994;367:375-6.
-
(1994)
Nature
, vol.367
, pp. 375-376
-
-
Hofstra, R.M.1
Landsvater, R.M.2
Ceccherini, I.3
-
25
-
-
0030799090
-
Activating mutations for the met tyrosine kinase receptor in human cancer
-
Jeffers M, Schmidt L, Nakaigawa N, et al. Activating mutations for the met tyrosine kinase receptor in human cancer. Proc Natl Acad Sci U S A 1997;94:11445-50.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 11445-11450
-
-
Jeffers, M.1
Schmidt, L.2
Nakaigawa, N.3
-
26
-
-
0028181118
-
Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor)
-
Longati P, Bardelli A, Ponzetto C, Naldini L, Comoglio PM. Tyrosines1234-1235 are critical for activation of the tyrosine kinase encoded by the MET proto-oncogene (HGF receptor). Oncogene 1994;9:49-57.
-
(1994)
Oncogene
, vol.9
, pp. 49-57
-
-
Longati, P.1
Bardelli, A.2
Ponzetto, C.3
Naldini, L.4
Comoglio, P.M.5
-
27
-
-
0009013631
-
Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: Establishment of clonality in a human mast cell neoplasm
-
Longley BJ, Tyrrell L, Lu SZ, et al. Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm. Nat Genet 1996;12:312-4.
-
(1996)
Nat Genet
, vol.12
, pp. 312-314
-
-
Longley, B.J.1
Tyrrell, L.2
Lu, S.Z.3
-
28
-
-
17344381429
-
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
-
Schmidt L, Duh FM, Chen F, et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet 1997;16:68-73.
-
(1997)
Nat Genet
, vol.16
, pp. 68-73
-
-
Schmidt, L.1
Duh, F.M.2
Chen, F.3
-
29
-
-
0026472124
-
-
Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD, Muller WJ. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci U S A 1992;89:10578-82.
-
Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD, Muller WJ. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci U S A 1992;89:10578-82.
-
-
-
-
30
-
-
0032547843
-
Reconstitution of mammary gland development in vitro: Requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis
-
Niemann C, Brinkmann V, Spitzer E, et al. Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis. J Cell Biol 1998;143:533-45.
-
(1998)
J Cell Biol
, vol.143
, pp. 533-545
-
-
Niemann, C.1
Brinkmann, V.2
Spitzer, E.3
-
31
-
-
18844475456
-
In vivo effects of hepatocyte growth factor/scatter factor on mouse mammary gland development
-
Yant J, Buluwela L, Niranjan B, Gusterson B, Kamalati T. In vivo effects of hepatocyte growth factor/scatter factor on mouse mammary gland development. Exp Cell Res 1998;241:476-81.
-
(1998)
Exp Cell Res
, vol.241
, pp. 476-481
-
-
Yant, J.1
Buluwela, L.2
Niranjan, B.3
Gusterson, B.4
Kamalati, T.5
-
32
-
-
0037103985
-
Activation of different Wnt/β-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors
-
Miyoshi K, Rosner A, Nozawa M, et al. Activation of different Wnt/β-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors. Oncogene 2002;21:5548-56.
-
(2002)
Oncogene
, vol.21
, pp. 5548-5556
-
-
Miyoshi, K.1
Rosner, A.2
Nozawa, M.3
-
33
-
-
0036733656
-
Pathway pathology: Histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors
-
Rosner A, Miyoshi K, Landesman-Bollag E, et al. Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors. Am J Pathol 2002;161:1087-97.
-
(2002)
Am J Pathol
, vol.161
, pp. 1087-1097
-
-
Rosner, A.1
Miyoshi, K.2
Landesman-Bollag, E.3
-
34
-
-
0029837671
-
A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype
-
Collesi C, Santoro MM, Gaudino G, Comoglio PM. A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype. Mol Cell Biol 1996;16:5518-26.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5518-5526
-
-
Collesi, C.1
Santoro, M.M.2
Gaudino, G.3
Comoglio, P.M.4
-
35
-
-
0033210752
-
Presence of RON receptor tyrosine kinase and its splicing variant in malignant and non-malignant human colonic mucosa
-
Okino T, Egami H, Ohmachi H, et al. Presence of RON receptor tyrosine kinase and its splicing variant in malignant and non-malignant human colonic mucosa. Int J Oncol 1999;15:709-14.
-
(1999)
Int J Oncol
, vol.15
, pp. 709-714
-
-
Okino, T.1
Egami, H.2
Ohmachi, H.3
-
36
-
-
0033859401
-
Identification of a novel splicing product of the RON receptor tyrosine kinase in human colorectal carcinoma cells
-
Wang MH, Kurtz AL, Chen Y. Identification of a novel splicing product of the RON receptor tyrosine kinase in human colorectal carcinoma cells. Carcinogenesis 2000;21:1507-12.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1507-1512
-
-
Wang, M.H.1
Kurtz, A.L.2
Chen, Y.3
-
37
-
-
0031948388
-
Requirement for both She and phosphatidylinositol 3′ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis
-
Webster MA, Hutchinson JN, Rauh MJ, et al. Requirement for both She and phosphatidylinositol 3′ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis. Mol Cell Biol 1998;18:2344-59.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2344-2359
-
-
Webster, M.A.1
Hutchinson, J.N.2
Rauh, M.J.3
-
38
-
-
0034715897
-
Overexpression and activation of the RON receptor tyrosine kinase in a panel of human colorectal carcinoma cell lines
-
Chen YQ, Zhou YQ, Angeloni D, Kurtz, AL, Qiang XZ, Wang MH. Overexpression and activation of the RON receptor tyrosine kinase in a panel of human colorectal carcinoma cell lines. Exp Cell Res 2000;261:229-38.
-
(2000)
Exp Cell Res
, vol.261
, pp. 229-238
-
-
Chen, Y.Q.1
Zhou, Y.Q.2
Angeloni, D.3
Kurtz, A.L.4
Qiang, X.Z.5
Wang, M.H.6
-
39
-
-
0037448657
-
Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: Generation of different splicing RON variants and their oncogenic potential
-
Zhou YQ, He C, Chen YQ, Wang D, Wang MH. Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential. Oncogene 2003;22:186-97.
-
(2003)
Oncogene
, vol.22
, pp. 186-197
-
-
Zhou, Y.Q.1
He, C.2
Chen, Y.Q.3
Wang, D.4
Wang, M.H.5
-
40
-
-
9144240012
-
RNA-mediated gene silencing of the RON receptor tyrosine kinase alters oncogenic phenotypes of human colorectal carcinoma cells
-
Xu XM, Wang D, Shen Q, Chen YQ, Wang MH. RNA-mediated gene silencing of the RON receptor tyrosine kinase alters oncogenic phenotypes of human colorectal carcinoma cells. Oncogene 2004;23:8464-74.
-
(2004)
Oncogene
, vol.23
, pp. 8464-8474
-
-
Xu, X.M.1
Wang, D.2
Shen, Q.3
Chen, Y.Q.4
Wang, M.H.5
-
41
-
-
0032564368
-
Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth
-
Bardelli A, Longati P, Gramaglia D, et al. Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth. Proc Natl Acad Sci U S A 1998;95:14379-83.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14379-14383
-
-
Bardelli, A.1
Longati, P.2
Gramaglia, D.3
-
42
-
-
0032564341
-
The mutationally activated Met receptor mediates motility and metastasis
-
Jeffers M, Fiscella M, Webb CP, Anver M, Koochekpour S, Vande Woude GF. The mutationally activated Met receptor mediates motility and metastasis. Proc Natl Acad Sci U S A 1998;95:14417-22.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14417-14422
-
-
Jeffers, M.1
Fiscella, M.2
Webb, C.P.3
Anver, M.4
Koochekpour, S.5
Vande Woude, G.F.6
-
43
-
-
0030927326
-
Activation of the JNK pathway is essential for transformation by the Met oncogene
-
Rodrigues GA, Park M, Schlessinger J. Activation of the JNK pathway is essential for transformation by the Met oncogene. EMBO J 1997;16:2634-45.
-
(1997)
EMBO J
, vol.16
, pp. 2634-2645
-
-
Rodrigues, G.A.1
Park, M.2
Schlessinger, J.3
|