Accumulation of pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage

Journal of Biological Chemistry

Volumn 284, Issue 11, 2009, Pages 7284-7293

  Gong, Zihua ^a   Cho, Young Wook ^b   Kim, Ja Eun ^a,c   Ge, Kai ^b   Chen, Junjie ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c Kyung Hee University Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; BINDING DOMAIN; CELL CYCLE; CELL SURVIVAL; CELLULAR EVENTS; CELLULAR SENSITIVITY; DNA BREAKS; DNA DAMAGE RESPONSE; DNA DAMAGES; DNA REPAIR; EUKARYOTIC CELLS; GENOMIC STABILITY; N-TERMINAL; SIGNALING PROTEINS; TRANSACTIVATION DOMAIN; TRANSCRIPTIONAL REGULATION;

CELL DEATH; COORDINATION REACTIONS; DNA; IONIZING RADIATION; NUCLEIC ACIDS;

GENES;

BINDING PROTEIN; CELL PROTEIN; HISTONE H2AX; NUCLEAR PROTEIN; PAX2 TRANSACTIVATION DOMAIN INTERACTION PROTEIN; PAX2 TRANSACTIVATION DOMAIN INTERACTION PROTEIN ASSOCIATED PROTEIN 1; PROTEIN MDC1; PROTEIN RNF8; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CARRIER PROTEIN; DNA BINDING PROTEIN; GAMMA H2AX PROTEIN, MOUSE; GAMMA-H2AX PROTEIN, MOUSE; H2AFX PROTEIN, HUMAN; HISTONE; MDC1 PROTEIN, HUMAN; MDC1 PROTEIN, MOUSE; MIXED LINEAGE LEUKEMIA PROTEIN; MLL PROTEIN, HUMAN; MLL PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; PAXIP1 PROTEIN, HUMAN; PAXIP1 PROTEIN, MOUSE; RNF8 PROTEIN, HUMAN; SIGNAL PEPTIDE; TRANSACTIVATOR PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ANIMAL; CHROMATIN; GAMMA RADIATION; GENETICS; HELA CELL; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; RADIATION EXPOSURE;

EUKARYOTA;

ANIMALS; CARRIER PROTEINS; CELL SURVIVAL; CHROMATIN; DNA BREAKS; DNA-BINDING PROTEINS; GAMMA RAYS; HELA CELLS; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MULTIPROTEIN COMPLEXES; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; TRANS-ACTIVATORS;

EID: 65149092552     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M809158200     Document Type: Article

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