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Volumn 114, Issue 3, 2005, Pages 146-154

Imaging of protein movement induced by chromosomal breakage: Tiny 'local' lesions pose great 'global' challenges

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; DNA; HISTONE H2A; PROTEIN P21; RAD50 PROTEIN; RAD51 PROTEIN;

EID: 25144514003     PISSN: 00095915     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00412-005-0011-y     Document Type: Review
Times cited : (93)

References (60)
  • 1
    • 0347988236 scopus 로고    scopus 로고
    • Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains
    • 10.1126/science.1088845
    • Aten JA, Stap J, Krawczyk PM, van Oven CH, Hoebe RA, Essers J, Kanaar R (2004) Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science 303:92-95 10.1126/science.1088845
    • (2004) Science , vol.303 , pp. 92-95
    • Aten, J.A.1    Stap, J.2    Krawczyk, P.M.3    van Oven, C.H.4    Hoebe, R.A.5    Essers, J.6    Kanaar, R.7
  • 2
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • 10.1038/nature01368
    • Bakkenist CJ, Kastan MB (2003) DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499-506 10.1038/nature01368
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 3
    • 3142534591 scopus 로고    scopus 로고
    • Initiating cellular stress responses
    • 10.1016/j.cell.2004.06.023
    • Bakkenist CJ, Kastan MB (2004) Initiating cellular stress responses. Cell 118:9-17 10.1016/j.cell.2004.06.023
    • (2004) Cell , vol.118 , pp. 9-17
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 5
    • 22944462083 scopus 로고    scopus 로고
    • Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are coordinated by Mdc1/NFBD1
    • in press
    • Bekker-Jensen S, Lukas C, Melander F, Bartek J, Lukas J (2005) Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are coordinated by Mdc1/NFBD1. J Cell Biol, in press
    • (2005) J. Cell Biol.
    • Bekker-Jensen, S.1    Lukas, C.2    Melander, F.3    Bartek, J.4    Lukas, J.5
  • 6
    • 0015106896 scopus 로고
    • Chromosomal microdissection by laser. A cytochemical and functional analysis
    • 10.1016/0014-4827(71)90413-7
    • Berns MW, Floyd AD (1971) Chromosomal microdissection by laser. A cytochemical and functional analysis. Exp Cell Res 67:305-310 10.1016/ 0014-4827(71)90413-7
    • (1971) Exp. Cell Res. , vol.67 , pp. 305-310
    • Berns, M.W.1    Floyd, A.D.2
  • 7
    • 0014559251 scopus 로고
    • Effects of laser micro-irradiation on chromosomes
    • 10.1016/0014-4827(69)90016-0
    • Berns MW, Rounds DE, Olson RS (1969) Effects of laser micro-irradiation on chromosomes. Exp Cell Res 56:292-298 10.1016/0014-4827(69)90016-0
    • (1969) Exp. Cell Res. , vol.56 , pp. 292-298
    • Berns, M.W.1    Rounds, D.E.2    Olson, R.S.3
  • 8
    • 0015211375 scopus 로고
    • Chromosome lesions produced with an argon laser microbeam without dye sensitization
    • 5541651
    • Berns MW, Cheng WK, Floyd AD, Onuki Y (1971) Chromosome lesions produced with an argon laser microbeam without dye sensitization. Science 171:903-905 5541651
    • (1971) Science , vol.171 , pp. 903-905
    • Berns, M.W.1    Cheng, W.K.2    Floyd, A.D.3    Onuki, Y.4
  • 9
    • 13944263628 scopus 로고    scopus 로고
    • Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage
    • 10.1038/ng1506
    • Bradshaw PS, Stavropoulos DJ, Meyn MS (2005) Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage. Nat Genet 37:193-197 10.1038/ng1506
    • (2005) Nat. Genet. , vol.37 , pp. 193-197
    • Bradshaw, P.S.1    Stavropoulos, D.J.2    Meyn, M.S.3
  • 11
    • 0035316574 scopus 로고    scopus 로고
    • Chromosome territories, nuclear architecture and gene regulation in mammalian cells
    • 10.1038/35066075
    • Cremer T, Cremer C (2001) Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat Rev Genet 2:292-310 10.1038/ 35066075
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 292-310
    • Cremer, T.1    Cremer, C.2
  • 12
    • 0020464770 scopus 로고
    • Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments
    • 10.1007/BF00333519
    • Cremer T, Cremer C, Schneider T, Baumann H, Hens L, Kirsch-Volders M (1982) Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments. Hum Genet 62:201-209 10.1007/BF00333519
    • (1982) Hum. Genet. , vol.62 , pp. 201-209
    • Cremer, T.1    Cremer, C.2    Schneider, T.3    Baumann, H.4    Hens, L.5    Kirsch-Volders, M.6
  • 14
    • 3042685445 scopus 로고    scopus 로고
    • Phosphorylation of histone H2B at DNA double-strand breaks
    • 10.1084/jem.20032247
    • Fernandez-Capetillo O, Allis CD, Nussenzweig A (2004) Phosphorylation of histone H2B at DNA double-strand breaks. J Exp Med 199:1671-1677 10.1084/ jem.20032247
    • (2004) J. Exp. Med. , vol.199 , pp. 1671-1677
    • Fernandez-Capetillo, O.1    Allis, C.D.2    Nussenzweig, A.3
  • 17
    • 0036153467 scopus 로고    scopus 로고
    • Characterization of CDKN1A (p21) binding to sites of heavy-ion-induced damage: Colocalization with proteins involved in DNA repair
    • 10.1080/09553000110090007
    • Jakob B, Scholz M, Taucher-Scholz G (2002) Characterization of CDKN1A (p21) binding to sites of heavy-ion-induced damage: Colocalization with proteins involved in DNA repair. Int J Radiat Biol 78:75-88 10.1080/ 09553000110090007
    • (2002) Int. J. Radiat. Biol. , vol.78 , pp. 75-88
    • Jakob, B.1    Scholz, M.2    Taucher-Scholz, G.3
  • 18
    • 0038301384 scopus 로고    scopus 로고
    • Biological imaging of heavy charged-particle tracks
    • 12710880
    • Jakob B, Scholz M, Taucher-Scholz G (2003) Biological imaging of heavy charged-particle tracks. Radiat Res 159:676-684 12710880
    • (2003) Radiat. Res. , vol.159 , pp. 676-684
    • Jakob, B.1    Scholz, M.2    Taucher-Scholz, G.3
  • 19
    • 0029899891 scopus 로고    scopus 로고
    • Genetic manipulation of genomes with rare-cutting endonucleases
    • 10.1016/0168-9525(96)10019-6
    • Jasin M (1996) Genetic manipulation of genomes with rare-cutting endonucleases. Trends Genet 12:224-228 10.1016/0168-9525(96)10019-6
    • (1996) Trends Genet. , vol.12 , pp. 224-228
    • Jasin, M.1
  • 20
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • 10.1126/science.1063127
    • Jenuwein T, Allis CD (2001) Translating the histone code. Science 293:1074-1080 10.1126/science.1063127
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 21
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • 10.1038/nature03097
    • Kastan MB, Bartek J (2004) Cell-cycle checkpoints and cancer. Nature 432:316-323 10.1038/nature03097
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 22
    • 0033971720 scopus 로고    scopus 로고
    • Centrosome-independent mitotic spindle formation in vertebrates
    • 10.1016/S0960-9822(99)00276-6
    • Khodjakov A, Cole RW, Oakley BR, Rieder CL (2000) Centrosome-independent mitotic spindle formation in vertebrates. Curr Biol 10:59-67 10.1016/ S0960-9822(99)00276-6
    • (2000) Curr. Biol. , vol.10 , pp. 59-67
    • Khodjakov, A.1    Cole, R.W.2    Oakley, B.R.3    Rieder, C.L.4
  • 23
    • 0346668366 scopus 로고    scopus 로고
    • Specific recruitment of human cohesin to laser-induced DNA damage
    • 10.1074/jbc.M209123200
    • Kim JS, Krasieva TB, LaMorte V, Taylor AM, Yokomori K (2002a) Specific recruitment of human cohesin to laser-induced DNA damage. J Biol Chem 277:45149-45153 10.1074/jbc.M209123200
    • (2002) J. Biol. Chem. , vol.277 , pp. 45149-45153
    • Kim, J.S.1    Krasieva, T.B.2    LaMorte, V.3    Taylor, A.M.4    Yokomori, K.5
  • 24
    • 0036500555 scopus 로고    scopus 로고
    • Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
    • 10.1101/gad.970602
    • Kim ST, Xu B, Kastan MB (2002b) Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev 16:560-570 10.1101/gad.970602
    • (2002) Genes Dev. , vol.16 , pp. 560-570
    • Kim, S.T.1    Xu, B.2    Kastan, M.B.3
  • 25
    • 3242889155 scopus 로고    scopus 로고
    • Interplay between chromatin and cell cycle checkpoints in the context of ATR/ATM-dependent checkpoints
    • 10.1016/j.dnarep.2004.03.010
    • Koundrioukoff S, Polo S, Almouzni G (2004) Interplay between chromatin and cell cycle checkpoints in the context of ATR/ATM-dependent checkpoints. DNA Repair (Amst) 3:969-978 10.1016/j.dnarep.2004.03.010
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 969-978
    • Koundrioukoff, S.1    Polo, S.2    Almouzni, G.3
  • 27
    • 0027190834 scopus 로고
    • A new method for introducing double-strand breaks into cellular DNA
    • 7683818
    • Limoli CL, Ward JF (1993) A new method for introducing double-strand breaks into cellular DNA. Radiat Res 134:160-169 7683818
    • (1993) Radiat. Res. , vol.134 , pp. 160-169
    • Limoli, C.L.1    Ward, J.F.2
  • 28
    • 0038141976 scopus 로고    scopus 로고
    • Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre
    • 10.1038/ncb997
    • Lisby M, Mortensen UH, Rothstein R (2003) Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre. Nat Cell Biol 5:572-577 10.1038/ncb997
    • (2003) Nat. Cell Biol. , vol.5 , pp. 572-577
    • Lisby, M.1    Mortensen, U.H.2    Rothstein, R.3
  • 29
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
    • 10.1016/j.cell.2004.08.015
    • Lisby M, Barlow JH, Burgess RC, Rothstein R (2004) Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins. Cell 118:699-713 10.1016/j.cell.2004.08.015
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 30
    • 0034192363 scopus 로고    scopus 로고
    • Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres
    • 10811102
    • Lombard DB, Guarente L (2000) Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res 60:2331-2334 10811102
    • (2000) Cancer Res. , vol.60 , pp. 2331-2334
    • Lombard, D.B.1    Guarente, L.2
  • 31
    • 4544362848 scopus 로고    scopus 로고
    • Watching the DNA repair ensemble dance
    • 10.1016/j.cell.2004.09.006
    • Lukas J, Bartek J (2004) Watching the DNA repair ensemble dance. Cell 118:666-668 10.1016/j.cell.2004.09.006
    • (2004) Cell , vol.118 , pp. 666-668
    • Lukas, J.1    Bartek, J.2
  • 32
    • 0037341599 scopus 로고    scopus 로고
    • Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
    • 10.1038/ncb945
    • Lukas C, Falck J, Bartkova J, Bartek J, Lukas J (2003) Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat Cell Biol 5:255-260 10.1038/ncb945
    • (2003) Nat. Cell Biol. , vol.5 , pp. 255-260
    • Lukas, C.1    Falck, J.2    Bartkova, J.3    Bartek, J.4    Lukas, J.5
  • 34
    • 3242890575 scopus 로고    scopus 로고
    • Mammalian cell cycle checkpoints: Signalling pathways and their organization in space and time
    • 10.1016/j.dnarep.2004.03.006
    • Lukas J, Lukas C, Bartek J (2004b) Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time. DNA Repair (Amst) 3:997-1007 10.1016/j.dnarep.2004.03.006
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 997-1007
    • Lukas, J.1    Lukas, C.2    Bartek, J.3
  • 35
    • 0037049548 scopus 로고    scopus 로고
    • Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by
    • 10.1083/jcb.200207115
    • Mahy NL, Perry PE, Bickmore WA (2002) Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH. J Cell Biol 159:753-763 10.1083/ jcb.200207115
    • (2002) FISH J. Cell Biol. , vol.159 , pp. 753-763
    • Mahy, N.L.1    Perry, P.E.2    Bickmore, W.A.3
  • 36
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • 11691833
    • Melo JA, Cohen J, Toczyski DP (2001) Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev 15:2809-2821 11691833
    • (2001) Genes Dev. , vol.15 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 37
    • 0037195281 scopus 로고    scopus 로고
    • DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
    • 10.1016/S0960-9822(02)01226-5
    • Mikhailov A, Cole RW, Rieder CL (2002) DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint. Curr Biol 12:1797-1806 10.1016/ S0960-9822(02)01226-5
    • (2002) Curr. Biol. , vol.12 , pp. 1797-1806
    • Mikhailov, A.1    Cole, R.W.2    Rieder, C.L.3
  • 38
    • 0034749425 scopus 로고    scopus 로고
    • DNA damage-dependent nuclear dynamics of the Mre11 complex
    • 10.1128/MCB.21.1.281-288.2001
    • Mirzoeva OK, Petrini JH (2001) DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol Cell Biol 21:281-288 10.1128/MCB.21.1.281-288.2001
    • (2001) Mol. Cell Biol. , vol.21 , pp. 281-288
    • Mirzoeva, O.K.1    Petrini, J.H.2
  • 39
    • 0037226818 scopus 로고    scopus 로고
    • DNA replication-dependent nuclear dynamics of the Mre11 complex
    • 12556560
    • Mirzoeva OK, Petrini JH (2003) DNA replication-dependent nuclear dynamics of the Mre11 complex. Mol Cancer Res 1:207-218 12556560
    • (2003) Mol. Cancer Res. , vol.1 , pp. 207-218
    • Mirzoeva, O.K.1    Petrini, J.H.2
  • 40
    • 18744375181 scopus 로고    scopus 로고
    • Concepts in nuclear architecture
    • 10.1002/bies.20226
    • Misteli T (2005) Concepts in nuclear architecture. BioEssays 27:477-487 10.1002/bies.20226
    • (2005) BioEssays , vol.27 , pp. 477-487
    • Misteli, T.1
  • 41
    • 0032562595 scopus 로고    scopus 로고
    • In situ visualization of DNA double-strand break repair in human fibroblasts
    • 10.1126/science.280.5363.590
    • Nelms BE, Maser RS, MacKay JF, Lagally MG, Petrini JH (1998) In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280:590-592 10.1126/science.280.5363.590
    • (1998) Science , vol.280 , pp. 590-592
    • Nelms, B.E.1    Maser, R.S.2    MacKay, J.F.3    Lagally, M.G.4    Petrini, J.H.5
  • 42
    • 0036948433 scopus 로고    scopus 로고
    • Toward maintaining the genome: DNA damage and replication checkpoints
    • 10.1146/annurev.genet.36.060402.113540
    • Nyberg KA, Michelson RJ, Putnam CW, Weinert TA (2002) Toward maintaining the genome: DNA damage and replication checkpoints. Annu Rev Genet 36:617-656 10.1146/annurev.genet.36.060402.113540
    • (2002) Annu. Rev. Genet. , vol.36 , pp. 617-656
    • Nyberg, K.A.1    Michelson, R.J.2    Putnam, C.W.3    Weinert, T.A.4
  • 44
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • 10.1016/S0960-9822(00)00610-2
    • Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM (2000) A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 10:886-895 10.1016/ S0960-9822(00)00610-2
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 45
    • 0142011461 scopus 로고    scopus 로고
    • The cellular response to DNA double-strand breaks: Defining the sensors and mediators
    • 10.1016/S0962-8924(03)00170-3
    • Petrini JH, Stracker TH (2003) The cellular response to DNA double-strand breaks: Defining the sensors and mediators. Trends Cell Biol 13:458-462 10.1016/S0962-8924(03)00170-3
    • (2003) Trends Cell Biol. , vol.13 , pp. 458-462
    • Petrini, J.H.1    Stracker, T.H.2
  • 46
    • 1642377367 scopus 로고    scopus 로고
    • Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy
    • 14870680
    • Phair RD, Gorski SA, Misteli T (2004a) Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods Enzymol 375:393-414 14870680
    • (2004) Methods Enzymol. , vol.375 , pp. 393-414
    • Phair, R.D.1    Gorski, S.A.2    Misteli, T.3
  • 47
    • 3042760021 scopus 로고    scopus 로고
    • Global nature of dynamic protein-chromatin interactions in vivo: Three-dimensional genome scanning and dynamic interaction networks of chromatin proteins
    • 10.1128/MCB.24.14.6393-6402.2004
    • Phair RD, Scaffidi P, Elbi C, Vecerova J, Dey A, Ozato K, Brown DT, Hager G, Bustin M, Misteli T (2004b) Global nature of dynamic protein-chromatin interactions in vivo: Three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol 24:6393-6402 10.1128/MCB.24.14.6393-6402.2004
    • (2004) Mol. Cell Biol. , vol.24 , pp. 6393-6402
    • Phair, R.D.1    Scaffidi, P.2    Elbi, C.3    Vecerova, J.4    Dey, A.5    Ozato, K.6    Brown, D.T.7    Hager, G.8    Bustin, M.9    Misteli, T.10
  • 48
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • 10.1083/jcb.146.5.905
    • Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146:905-916 10.1083/jcb.146.5.905
    • (1999) J. Cell Biol. , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 49
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • 10.1038/nrc1011
    • Shiloh Y (2003) ATM and related protein kinases: Safeguarding genome integrity. Nat Rev Cancer 3:155-168 10.1038/nrc1011
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 50
    • 5444221921 scopus 로고    scopus 로고
    • Maintaining integrity
    • 10.1038/ncb1004-923
    • Shiloh Y, Lehmann AR (2004) Maintaining integrity. Nat Cell Biol 6:923-928 10.1038/ncb1004-923
    • (2004) Nat. Cell Biol. , vol.6 , pp. 923-928
    • Shiloh, Y.1    Lehmann, A.R.2
  • 51
    • 10944232673 scopus 로고    scopus 로고
    • Postreplicative recruitment of cohesin to double-strand breaks is required for DNA Repair
    • 10.1016/j.molcel.2004.11.026
    • Strom L, Lindroos HB, Shirahige K, Sjogren C (2004) Postreplicative recruitment of cohesin to double-strand breaks is required for DNA Repair. Mol Cell 16:1003-1015 10.1016/j.molcel.2004.11.026
    • (2004) Mol. Cell , vol.16 , pp. 1003-1015
    • Strom, L.1    Lindroos, H.B.2    Shirahige, K.3    Sjogren, C.4
  • 52
    • 0034710152 scopus 로고    scopus 로고
    • Rad51 accumulation at sites of DNA damage and in postreplicative chromatin
    • 10.1083/jcb.150.2.283
    • Tashiro S, Walter J, Shinohara A, Kamada N, Cremer T (2000) Rad51 accumulation at sites of DNA damage and in postreplicative chromatin. J Cell Biol 150:283-291 10.1083/jcb.150.2.283
    • (2000) J. Cell Biol. , vol.150 , pp. 283-291
    • Tashiro, S.1    Walter, J.2    Shinohara, A.3    Kamada, N.4    Cremer, T.5
  • 53
    • 10944262393 scopus 로고    scopus 로고
    • DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain
    • 10.1016/j.molcel.2004.11.027
    • Unal E, Arbel-Eden A, Sattler U, Shroff R, Lichten M, Haber JE, Koshland D (2004) DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol Cell 16:991-1002 10.1016/j.molcel.2004.11.027
    • (2004) Mol. Cell , vol.16 , pp. 991-1002
    • Unal, E.1    Arbel-Eden, A.2    Sattler, U.3    Shroff, R.4    Lichten, M.5    Haber, J.E.6    Koshland, D.7
  • 54
    • 0037328374 scopus 로고    scopus 로고
    • A new system for laser-UVA-microirradiation of living cells
    • 10.1046/j.1365-2818.2003.01117.x
    • Walter J, Cremer T, Miyagawa K, Tashiro S (2003) A new system for laser-UVA-microirradiation of living cells. J Microsc 209:71-75 10.1046/ j.1365-2818.2003.01117.x
    • (2003) J. Microsc. , vol.209 , pp. 71-75
    • Walter, J.1    Cremer, T.2    Miyagawa, K.3    Tashiro, S.4
  • 55
    • 0034730633 scopus 로고    scopus 로고
    • NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/ G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres
    • 10.1074/jbc.C000390200
    • Wu G, Lee WH, Chen PL (2000) NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres. J Biol Chem 275:30618-30622 10.1074/ jbc.C000390200
    • (2000) J. Biol. Chem. , vol.275 , pp. 30618-30622
    • Wu, G.1    Lee, W.H.2    Chen, P.L.3
  • 56
    • 0037843426 scopus 로고    scopus 로고
    • Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1
    • 12750284
    • Wu G, Jiang X, Lee WH, Chen PL (2003) Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1. Cancer Res 63:2589-2595 12750284
    • (2003) Cancer Res. , vol.63 , pp. 2589-2595
    • Wu, G.1    Jiang, X.2    Lee, W.H.3    Chen, P.L.4
  • 57
    • 0036847998 scopus 로고    scopus 로고
    • PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2
    • 10.1038/ncb869
    • Yang S, Kuo C, Bisi JE, Kim MK (2002) PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2. Nat Cell Biol 4:865-870 10.1038/ncb869
    • (2002) Nat. Cell Biol. , vol.4 , pp. 865-870
    • Yang, S.1    Kuo, C.2    Bisi, J.E.3    Kim, M.K.4
  • 58
    • 0036500690 scopus 로고    scopus 로고
    • SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
    • 10.1101/gad.970702
    • Yazdi PT, Wang Y, Zhao S, Patel N, Lee EY, Qin J (2002) SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev 16:571-582 10.1101/gad.970702
    • (2002) Genes Dev. , vol.16 , pp. 571-582
    • Yazdi, P.T.1    Wang, Y.2    Zhao, S.3    Patel, N.4    Lee, E.Y.5    Qin, J.6
  • 59
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • 10.1038/35044005
    • Zhou BB, Elledge SJ (2000) The DNA damage response: Putting checkpoints in perspective. Nature 408:433-439 10.1038/35044005
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2
  • 60
    • 0342561644 scopus 로고    scopus 로고
    • Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
    • 10.1038/77139
    • Zhu XD, Kuster B, Mann M, Petrini JH, de Lange T (2000) Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet 25:347-352 10.1038/77139
    • (2000) Nat. Genet. , vol.25 , pp. 347-352
    • Zhu, X.D.1    Kuster, B.2    Mann, M.3    Petrini, J.H.4    de Lange, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.