Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression

Journal of Biological Chemistry

Volumn 279, Issue 32, 2004, Pages 33909-33918

  Choudhury, Atish D ^a   Xu, Hong ^a   Baer, Richard ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CATALYSIS; CELL CULTURE; COMPLEXATION; DIMERS; GENES; TUMORS;

STEADY-STATE LEVELS; TUMOR SUPPRESSORS;

BIOCHEMISTRY;

BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA1 PROTEIN; E3 LIGASE; GENE PRODUCT; LIGASE; NOCODAZOLE; PROTEASOME; PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL LEVEL; CONJUGATE; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; METAPHASE; MITOSIS; ONCOGENE; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN CONTENT; PROTEIN DEGRADATION; REGULATORY MECHANISM; UBIQUITINATION;

BRCA1 PROTEIN; CELL CYCLE; CELL LINE; CYSTEINE ENDOPEPTIDASES; G1 PHASE; G2 PHASE; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; KINETICS; MITOSIS; MULTIENZYME COMPLEXES; NOCODAZOLE; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; S PHASE; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; URINARY BLADDER NEOPLASMS;

EID: 4043130959     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403646200     Document Type: Article

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