-
2
-
-
0032822103
-
Principles of protein folding in the cellular environment
-
Ellis, R.J.; Hartl, F.U. Principles of protein folding in the cellular environment. Curr. Opin. Struct. Biol. 1999, 9, 102-110.
-
(1999)
Curr. Opin. Struct. Biol.
, vol.9
, pp. 102-110
-
-
Ellis, R.J.1
Hartl, F.U.2
-
3
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
Morimoto, R.I. Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev. 2008, 22, 1427-1438.
-
(2008)
Genes Dev.
, vol.22
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
4
-
-
0032842870
-
The fundamentals of protein folding: Bringing together theory and experiment
-
Dobson, C.M.; Karplus, M. The fundamentals of protein folding: bringing together theory and experiment. Curr. Opin. Struct. Biol. 1999, 9, 92-101.
-
(1999)
Curr. Opin. Struct. Biol.
, vol.9
, pp. 92-101
-
-
Dobson, C.M.1
Karplus, M.2
-
5
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl, F.U.; Hayer-Hartl, M. Molecular chaperones in the cytosol: From nascent chain to folded protein. Science 2002, 295, 1852-1858.
-
(2002)
Science
, vol.295
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
6
-
-
0035478585
-
Macromolecular crowding: Obvious but underappreciated
-
Ellis, R.J. Macromolecular crowding: Obvious but underappreciated. Trends Biochem. Sci. 2001, 26, 597-604.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 597-604
-
-
Ellis, R.J.1
-
7
-
-
0025303147
-
Interaction of Hsp 70 with newly synthesized proteins: Implications for protein folding and assembly
-
Beckmann, R.P.; Mizzen, L.E.; Welch, W.J. Interaction of Hsp 70 with newly synthesized proteins: Implications for protein folding and assembly. Science 1990, 248, 850-854.
-
(1990)
Science
, vol.248
, pp. 850-854
-
-
Beckmann, R.P.1
Mizzen, L.E.2
Welch, W.J.3
-
8
-
-
0028361309
-
Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones
-
Frydman, J.; Nimmesgern, E.; Ohtsuka, K.; Hartl, F.U. Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones. Nature 1994, 370, 111-117.
-
(1994)
Nature
, vol.370
, pp. 111-117
-
-
Frydman, J.1
Nimmesgern, E.2
Ohtsuka, K.3
Hartl, F.U.4
-
9
-
-
0030928059
-
Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells
-
Eggers, D.K.; Welch, W.J.; Hansen, W.J. Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells. Mol. Biol. Cell 1997, 8, 1559-1573.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 1559-1573
-
-
Eggers, D.K.1
Welch, W.J.2
Hansen, W.J.3
-
10
-
-
0032489016
-
The Hsp70 and Hsp60 chaperone machines
-
Bukau, B.; Horwich, A.L. The Hsp70 and Hsp60 chaperone machines. Cell 1998, 92, 351-366.
-
(1998)
Cell
, vol.92
, pp. 351-366
-
-
Bukau, B.1
Horwich, A.L.2
-
11
-
-
0033032592
-
Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains
-
Teter, S.A.; Houry, W.A.; Ang, D.; Tradler, T.; Rockabrand, D.; Fischer, G.; Blum, P.; Georgopoulos, C.; Hartl, F.U. Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains. Cell 1999, 97, 755-765.
-
(1999)
Cell
, vol.97
, pp. 755-765
-
-
Teter, S.A.1
Houry, W.A.2
Ang, D.3
Tradler, T.4
Rockabrand, D.5
Fischer, G.6
Blum, P.7
Georgopoulos, C.8
Hartl, F.U.9
-
12
-
-
0033521588
-
In vivo newly translated polypeptides are sequestered in a protected folding environment
-
Thulasiraman, V.; Yang, C.F.; Frydman, J. In vivo newly translated polypeptides are sequestered in a protected folding environment. EMBO J. 1999, 18, 85-95.
-
(1999)
EMBO J.
, vol.18
, pp. 85-95
-
-
Thulasiraman, V.1
Yang, C.F.2
Frydman, J.3
-
13
-
-
0037315208
-
Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery
-
Pratt, W.B.; Toft, D.O. Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. Exp. Biol. Med. (Maywood) 2003, 228, 111-133.
-
(2003)
Exp. Biol. Med. (Maywood)
, vol.228
, pp. 111-133
-
-
Pratt, W.B.1
Toft, D.O.2
-
14
-
-
0037416154
-
The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo
-
Riggs, D.L.; Roberts, P.J.; Chirillo, S.C.; Cheung-Flynn, J.; Prapapanich, V.; Ratajczak, T.; Gaber, R.; Picard, D.; Smith, D.F. The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo. EMBO J. 2003, 22, 1158-1167.
-
(2003)
EMBO J.
, vol.22
, pp. 1158-1167
-
-
Riggs, D.L.1
Roberts, P.J.2
Chirillo, S.C.3
Cheung-Flynn, J.4
Prapapanich, V.5
Ratajczak, T.6
Gaber, R.7
Picard, D.8
Smith, D.F.9
-
15
-
-
0034892432
-
Hsp90: Chaperoning signal transduction
-
Richter, K.; Buchner, J. Hsp90: Chaperoning signal transduction. J. Cell Physiol. 2001, 188, 281-290.
-
(2001)
J. Cell Physiol.
, vol.188
, pp. 281-290
-
-
Richter, K.1
Buchner, J.2
-
16
-
-
5044239107
-
Pathways of chaperone-mediated protein folding in the cytosol
-
Young, J.C.; Agashe, V.R.; Siegers, K.; Hartl, F.U. Pathways of chaperone-mediated protein folding in the cytosol. Nat. Rev. Mol. Cell Biol. 2004, 5, 781-791.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 781-791
-
-
Young, J.C.1
Agashe, V.R.2
Siegers, K.3
Hartl, F.U.4
-
17
-
-
0642377466
-
More than folding: Localized functions of cytosolic chaperones
-
Young, J.C.; Barral, J.M.; Hartl, F.U. More than folding: Localized functions of cytosolic chaperones. Trends Biochem. Sci. 2003, 28, 541-547.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 541-547
-
-
Young, J.C.1
Barral, J.M.2
Hartl, F.U.3
-
18
-
-
0026776331
-
A cytoplasmic chaperonin that catalyzes beta-actin folding
-
Gao, Y.; Thomas, J.O.; Chow, R.L.; Lee, G.H.; Cowan, N.J. A cytoplasmic chaperonin that catalyzes beta-actin folding. Cell 1992, 69, 1043-1050.
-
(1992)
Cell
, vol.69
, pp. 1043-1050
-
-
Gao, Y.1
Thomas, J.O.2
Chow, R.L.3
Lee, G.H.4
Cowan, N.J.5
-
19
-
-
0026650749
-
TCP1 complex is a molecular chaperone in tubulin biogenesis
-
Yaffe, M.B.; Farr, G.W.; Miklos, D.; Horwich, A.L.; Sternlicht, M.L.; Sternlicht, H. TCP1 complex is a molecular chaperone in tubulin biogenesis. Nature 1992, 358, 245-248.
-
(1992)
Nature
, vol.358
, pp. 245-248
-
-
Yaffe, M.B.1
Farr, G.W.2
Miklos, D.3
Horwich, A.L.4
Sternlicht, M.L.5
Sternlicht, H.6
-
20
-
-
0030730821
-
Chaperonin-mediated folding in the eukaryotic cytosol proceeds through rounds of release of native and nonnative forms
-
Farr, G.W.; Scharl, E.C.; Schumacher, R.J.; Sondek, S.; Horwich, A.L. Chaperonin-mediated folding in the eukaryotic cytosol proceeds through rounds of release of native and nonnative forms. Cell 1997, 89, 927-937.
-
(1997)
Cell
, vol.89
, pp. 927-937
-
-
Farr, G.W.1
Scharl, E.C.2
Schumacher, R.J.3
Sondek, S.4
Horwich, A.L.5
-
21
-
-
0031725057
-
Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT
-
Won, K.A.; Schumacher, R.J.; Farr, G.W.; Horwich, A.L.; Reed, S.I. Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. Mol. Cell Biol. 1998, 18, 7584-7589.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 7584-7589
-
-
Won, K.A.1
Schumacher, R.J.2
Farr, G.W.3
Horwich, A.L.4
Reed, S.I.5
-
22
-
-
74249083867
-
On the role of the chaperonin CCT in the just-in-time assembly process of APC/CCdc20
-
Dekker, C. On the role of the chaperonin CCT in the just-in-time assembly process of APC/CCdc20. FEBS Lett. 2010, 584, 477-481.
-
(2010)
FEBS Lett.
, vol.584
, pp. 477-481
-
-
Dekker, C.1
-
23
-
-
0033400674
-
Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC
-
Feldman, D.E.; Thulasiraman, V.; Ferreyra, R.G.; Frydman, J. Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC. Mol. Cell 1999, 4, 1051-1061.
-
(1999)
Mol. Cell
, vol.4
, pp. 1051-1061
-
-
Feldman, D.E.1
Thulasiraman, V.2
Ferreyra, R.G.3
Frydman, J.4
-
24
-
-
23744457478
-
Versatility of the endoplasmic reticulum protein folding factory
-
van Anken, E.; Braakman, I. Versatility of the endoplasmic reticulum protein folding factory. Crit. Rev. Biochem. Mol. Biol. 2005, 40, 191-228.
-
(2005)
Crit. Rev. Biochem. Mol. Biol.
, vol.40
, pp. 191-228
-
-
Van Anken, E.1
Braakman, I.2
-
25
-
-
0034923677
-
The signal recognition particle
-
Keenan, R.J.; Freymann, D.M.; Stroud, R.M.; Walter, P. The signal recognition particle. Annu. Rev. Biochem. 2001, 70, 755-775.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 755-775
-
-
Keenan, R.J.1
Freymann, D.M.2
Stroud, R.M.3
Walter, P.4
-
26
-
-
0142215475
-
Global analysis of protein expression in yeast
-
Ghaemmaghami, S.; Huh, W.K.; Bower, K.; Howson, R.W.; Belle, A.; Dephoure, N.; O'Shea, E.K.; Weissman, J.S. Global analysis of protein expression in yeast. Nature 2003, 425, 737-741.
-
(2003)
Nature
, vol.425
, pp. 737-741
-
-
Ghaemmaghami, S.1
Huh, W.K.2
Bower, K.3
Howson, R.W.4
Belle, A.5
Dephoure, N.6
O'Shea, E.K.7
Weissman, J.S.8
-
27
-
-
3142587059
-
Protein folding and quality control in the endoplasmic reticulum
-
Kleizen, B.; Braakman, I. Protein folding and quality control in the endoplasmic reticulum. Curr. Opin. Cell Biol. 2004, 16, 343-349.
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 343-349
-
-
Kleizen, B.1
Braakman, I.2
-
28
-
-
33646127577
-
Molecular chaperones and protein quality control
-
Bukau, B.; Weissman, J.; Horwich, A. Molecular chaperones and protein quality control. Cell 2006, 125, 443-451.
-
(2006)
Cell
, vol.125
, pp. 443-451
-
-
Bukau, B.1
Weissman, J.2
Horwich, A.3
-
29
-
-
77953028045
-
Endoplasmic reticulum associated protein degradation: A chaperone assisted journey to hell
-
Stolz, A.; Wolf, D.H. Endoplasmic reticulum associated protein degradation: A chaperone assisted journey to hell. Biochim. Biophys. Acta 2010, 1803, 694-705.
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 694-705
-
-
Stolz, A.1
Wolf, D.H.2
-
30
-
-
0037336295
-
Quality control in the endoplasmic reticulum
-
Ellgaard, L.; Helenius, A. Quality control in the endoplasmic reticulum. Nat. Rev. Mol. Cell Biol. 2003, 4, 181-191.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 181-191
-
-
Ellgaard, L.1
Helenius, A.2
-
31
-
-
0032549767
-
BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation
-
Hamman, B.D.; Hendershot, L.M.; Johnson, A.E. BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation. Cell 1998, 92, 747-758.
-
(1998)
Cell
, vol.92
, pp. 747-758
-
-
Hamman, B.D.1
Hendershot, L.M.2
Johnson, A.E.3
-
32
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
Van den Berg, B.; Clemons, W.M., Jr.; Collinson, I.; Modis, Y.; Hartmann, E.; Harrison, S.C.; Rapoport, T.A. X-ray structure of a protein-conducting channel. Nature 2004, 427, 36-44.
-
(2004)
Nature
, vol.427
, pp. 36-44
-
-
Van Den Berg, B.1
Clemons Jr., W.M.2
Collinson, I.3
Modis, Y.4
Hartmann, E.5
Harrison, S.C.6
Rapoport, T.A.7
-
33
-
-
0033208953
-
Role and regulation of the ER chaperone BiP
-
Gething, M.J. Role and regulation of the ER chaperone BiP. Semin. Cell Dev. Biol. 1999, 10, 465-472.
-
(1999)
Semin. Cell Dev. Biol.
, vol.10
, pp. 465-472
-
-
Gething, M.J.1
-
34
-
-
0037428470
-
ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress
-
Cunnea, P.M.; Miranda-Vizuete, A.; Bertoli, G.; Simmen, T.; Damdimopoulos, A.E.; Hermann, S.; Leinonen, S.; Huikko, M.P.; Gustafsson, J.A.; Sitia, R.; Spyrou, G. ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress. J. Biol. Chem. 2003, 278, 1059-1066.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1059-1066
-
-
Cunnea, P.M.1
Miranda-Vizuete, A.2
Bertoli, G.3
Simmen, T.4
Damdimopoulos, A.E.5
Hermann, S.6
Leinonen, S.7
Huikko, M.P.8
Gustafsson, J.A.9
Sitia, R.10
Spyrou, G.11
-
35
-
-
0037013252
-
Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress
-
Shen, Y.; Meunier, L.; Hendershot, L.M. Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress. J. Biol. Chem. 2002, 277, 15947-15956.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15947-15956
-
-
Shen, Y.1
Meunier, L.2
Hendershot, L.M.3
-
36
-
-
0028170231
-
Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum
-
Melnick, J.; Dul, J.L.; Argon, Y. Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum. Nature 1994, 370, 373-375.
-
(1994)
Nature
, vol.370
, pp. 373-375
-
-
Melnick, J.1
Dul, J.L.2
Argon, Y.3
-
37
-
-
0028656507
-
Association of Hsp47, Grp78, and Grp94 with procollagen supports the successive or coupled action of molecular chaperones
-
Ferreira, L.R.; Norris, K.; Smith, T.; Hebert, C.; Sauk, J.J. Association of Hsp47, Grp78, and Grp94 with procollagen supports the successive or coupled action of molecular chaperones. J. Cell Biochem. 1994, 56, 518-526.
-
(1994)
J. Cell Biochem.
, vol.56
, pp. 518-526
-
-
Ferreira, L.R.1
Norris, K.2
Smith, T.3
Hebert, C.4
Sauk, J.J.5
-
38
-
-
0034733916
-
Glycoprotein folding in the endoplasmic reticulum: A tale of three chaperones?
-
High, S.; Lecomte, F.J.; Russell, S.J.; Abell, B.M.; Oliver, J.D. Glycoprotein folding in the endoplasmic reticulum: A tale of three chaperones? FEBS Lett. 2000, 476, 38-41.
-
(2000)
FEBS Lett.
, vol.476
, pp. 38-41
-
-
High, S.1
Lecomte, F.J.2
Russell, S.J.3
Abell, B.M.4
Oliver, J.D.5
-
40
-
-
2442761708
-
The protein disulphide-isomerase family: Unravelling a string of folds
-
Ferrari, D.M.; Soling, H.D. The protein disulphide-isomerase family: Unravelling a string of folds. Biochem. J. 1999, 339, 1-10.
-
(1999)
Biochem. J.
, vol.339
, pp. 1-10
-
-
Ferrari, D.M.1
Soling, H.D.2
-
41
-
-
0032513212
-
Enhanced catalysis of ribonuclease B folding by the interaction of calnexin or calreticulin with ERp57
-
Zapun, A.; Darby, N.J.; Tessier, D.C.; Michalak, M.; Bergeron, J.J.; Thomas, D.Y. Enhanced catalysis of ribonuclease B folding by the interaction of calnexin or calreticulin with ERp57. J. Biol. Chem. 1998, 273, 6009-6012.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6009-6012
-
-
Zapun, A.1
Darby, N.J.2
Tessier, D.C.3
Michalak, M.4
Bergeron, J.J.5
Thomas, D.Y.6
-
42
-
-
70350784082
-
Mitochondrial ATP-independent chaperones
-
Petrakis, N.; Alcock, F.; Tokatlidis, K. Mitochondrial ATP-independent chaperones. IUBMB Life 2009, 61, 909-914.
-
(2009)
IUBMB Life
, vol.61
, pp. 909-914
-
-
Petrakis, N.1
Alcock, F.2
Tokatlidis, K.3
-
43
-
-
71749108967
-
Mitochondrial protein homeostasis: The cooperative roles of chaperones and proteases
-
Voos, W. Mitochondrial protein homeostasis: The cooperative roles of chaperones and proteases. Res. Microbiol. 2009, 160, 718-725.
-
(2009)
Res. Microbiol.
, vol.160
, pp. 718-725
-
-
Voos, W.1
-
44
-
-
74549138158
-
Chaperoning histones during DNA replication and repair
-
Ransom, M.; Dennehey, B.K.; Tyler, J.K. Chaperoning histones during DNA replication and repair. Cell 2010, 140, 183-195.
-
(2010)
Cell
, vol.140
, pp. 183-195
-
-
Ransom, M.1
Dennehey, B.K.2
Tyler, J.K.3
-
45
-
-
77950369259
-
Moonlighting proteins: An intriguing mode of multitasking
-
Huberts, D.H.; van der Klei, I.J. Moonlighting proteins: An intriguing mode of multitasking. Biochim. Biophys. Acta 2010, 1803, 520-525.
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 520-525
-
-
Huberts, D.H.1
Van Der Klei, I.J.2
-
46
-
-
62949096122
-
Moonlighting proteins-an update
-
Jeffery, C.J. Moonlighting proteins-an update. Mol. Biosyst. 2009, 5, 345-350.
-
(2009)
Mol. Biosyst.
, vol.5
, pp. 345-350
-
-
Jeffery, C.J.1
-
47
-
-
9944225262
-
Molecular mechanisms for multitasking: Recent crystal structures of moonlighting proteins
-
Jeffery, C.J. Molecular mechanisms for multitasking: Recent crystal structures of moonlighting proteins. Curr. Opin. Struct. Biol. 2004, 14, 663-668.
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 663-668
-
-
Jeffery, C.J.1
-
48
-
-
2542464938
-
Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function
-
Jang, H.H.; Lee, K.O.; Chi, Y.H.; Jung, B.G.; Park, S.K.; Park, J.H.; Lee, J.R.; Lee, S.S.; Moon, J.C.; Yun, J.W.; Choi, Y.O.; Kim, W.Y.; Kang, J.S.; Cheong, G.W.; Yun, D.J.; Rhee, S.G.; Cho, M.J.; Lee, S.Y. Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function. Cell 2004, 117, 625-635.
-
(2004)
Cell
, vol.117
, pp. 625-635
-
-
Jang, H.H.1
Lee, K.O.2
Chi, Y.H.3
Jung, B.G.4
Park, S.K.5
Park, J.H.6
Lee, J.R.7
Lee, S.S.8
Moon, J.C.9
Yun, J.W.10
Choi, Y.O.11
Kim, W.Y.12
Kang, J.S.13
Cheong, G.W.14
Yun, D.J.15
Rhee, S.G.16
Cho, M.J.17
Lee, S.Y.18
-
49
-
-
23344451043
-
2- induced cell death
-
2- induced cell death. J. Biol. Chem. 2005, 280, 28775-28784.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28775-28784
-
-
Moon, J.C.1
Hah, Y.S.2
Kim, W.Y.3
Jung, B.G.4
Jang, H.H.5
Lee, J.R.6
Kim, S.Y.7
Lee, Y.M.8
Jeon, M.G.9
Kim, C.W.10
Cho, M.J.11
Lee, S.Y.12
-
50
-
-
29344451931
-
Phosphorylation and concomitant structural changes in human 2-Cys peroxiredoxin isotype I differentially regulate its peroxidase and molecular chaperone functions
-
Jang, H.H.; Kim, S.Y.; Park, S.K.; Jeon, H.S.; Lee, Y.M.; Jung, J.H.; Lee, S.Y.; Chae, H.B.; Jung, Y.J.; Lee, K.O.; Lim, C.O.; Chung, W.S.; Bahk, J.D.; Yun, D.J.; Cho, M.J. Phosphorylation and concomitant structural changes in human 2-Cys peroxiredoxin isotype I differentially regulate its peroxidase and molecular chaperone functions. FEBS Lett. 2006, 580, 351-355.
-
(2006)
FEBS Lett.
, vol.580
, pp. 351-355
-
-
Jang, H.H.1
Kim, S.Y.2
Park, S.K.3
Jeon, H.S.4
Lee, Y.M.5
Jung, J.H.6
Lee, S.Y.7
Chae, H.B.8
Jung, Y.J.9
Lee, K.O.10
Lim, C.O.11
Chung, W.S.12
Bahk, J.D.13
Yun, D.J.14
Cho, M.J.15
-
51
-
-
0038644836
-
Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis
-
Zhang, X.; Kurnasov, O.V.; Karthikeyan, S.; Grishin, N.V.; Osterman, A.L.; Zhang, H. Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis. J. Biol. Chem. 2003, 278, 13503-13511.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13503-13511
-
-
Zhang, X.1
Kurnasov, O.V.2
Karthikeyan, S.3
Grishin, N.V.4
Osterman, A.L.5
Zhang, H.6
-
52
-
-
68949210360
-
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme
-
Zhai, R.G.; Rizzi, M.; Garavaglia, S. Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme. Cell Mol. Life Sci. 2009, 66, 2805-2818.
-
(2009)
Cell Mol. Life Sci.
, vol.66
, pp. 2805-2818
-
-
Zhai, R.G.1
Rizzi, M.2
Garavaglia, S.3
-
53
-
-
33845477523
-
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity
-
Zhai, R.G.; Cao, Y.; Hiesinger, P.R.; Zhou, Y.; Mehta, S.Q.; Schulze, K.L.; Verstreken, P.; Bellen, H.J. Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. PLoS Biol. 2006, 4, e416.
-
(2006)
PLoS Biol.
, vol.4
-
-
Zhai, R.G.1
Cao, Y.2
Hiesinger, P.R.3
Zhou, Y.4
Mehta, S.Q.5
Schulze, K.L.6
Verstreken, P.7
Bellen, H.J.8
-
54
-
-
42249103603
-
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
-
Zhai, R.G.; Zhang, F.; Hiesinger, P.R.; Cao, Y.; Haueter, C.M.; Bellen, H.J. NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature 2008, 452, 887-891.
-
(2008)
Nature
, vol.452
, pp. 887-891
-
-
Zhai, R.G.1
Zhang, F.2
Hiesinger, P.R.3
Cao, Y.4
Haueter, C.M.5
Bellen, H.J.6
-
55
-
-
0028363670
-
Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila
-
Cutforth, T.; Rubin, G.M. Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila. Cell 1994, 77, 1027-1036.
-
(1994)
Cell
, vol.77
, pp. 1027-1036
-
-
Cutforth, T.1
Rubin, G.M.2
-
56
-
-
0032924953
-
Hsp90 & Co. A holding for folding
-
Buchner, J. Hsp90 & Co. a holding for folding. Trends Biochem. Sci. 1999, 24, 136-141.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 136-141
-
-
Buchner, J.1
-
57
-
-
0031873752
-
The 90-kDa molecular chaperone family: Structure, function, and clinical applications. A comprehensive review
-
Csermely, P.; Schnaider, T.; Soti, C.; Prohaszka, Z.; Nardai, G. The 90-kDa molecular chaperone family: Structure, function, and clinical applications. A comprehensive review. Pharmacol. Ther. 1998, 79, 129-168.
-
(1998)
Pharmacol. Ther.
, vol.79
, pp. 129-168
-
-
Csermely, P.1
Schnaider, T.2
Soti, C.3
Prohaszka, Z.4
Nardai, G.5
-
58
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent
-
Stebbins, C.E.; Russo, A.A.; Schneider, C.; Rosen, N.; Hartl, F.U.; Pavletich, N.P. Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent. Cell 1997, 89, 239-250.
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
59
-
-
0029003444
-
Structural organization of procaryotic and eucaryotic Hsp90. Influence of divalent cations on structure and function
-
Jakob, U.; Meyer, I.; Bugl, H.; Andre, S.; Bardwell, J.C.; Buchner, J. Structural organization of procaryotic and eucaryotic Hsp90. Influence of divalent cations on structure and function. J. Biol. Chem. 1995, 270, 14412-14419.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14412-14419
-
-
Jakob, U.1
Meyer, I.2
Bugl, H.3
Andre, S.4
Bardwell, J.C.5
Buchner, J.6
-
60
-
-
33744931946
-
Hsp90 recognizes a common surface on client kinases
-
Citri, A.; Harari, D.; Shohat, G.; Ramakrishnan, P.; Gan, J.; Lavi, S.; Eisenstein, M.; Kimchi, A.; Wallach, D.; Pietrokovski, S.; Yarden, Y. Hsp90 recognizes a common surface on client kinases. J. Biol. Chem. 2006, 281, 14361-14369.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14361-14369
-
-
Citri, A.1
Harari, D.2
Shohat, G.3
Ramakrishnan, P.4
Gan, J.5
Lavi, S.6
Eisenstein, M.7
Kimchi, A.8
Wallach, D.9
Pietrokovski, S.10
Yarden, Y.11
-
61
-
-
0036500652
-
C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest
-
Wang, H.; Goode, T.; Iakova, P.; Albrecht, J.H.; Timchenko, N.A. C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest. EMBO J. 2002, 21, 930-941.
-
(2002)
EMBO J.
, vol.21
, pp. 930-941
-
-
Wang, H.1
Goode, T.2
Iakova, P.3
Albrecht, J.H.4
Timchenko, N.A.5
-
62
-
-
0028298227
-
Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombe
-
Shiozaki, K.; Akhavan-Niaki, H.; McGowan, C.H.; Russell, P. Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombe. Mol. Cell Biol. 1994, 14, 3742-3751.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 3742-3751
-
-
Shiozaki, K.1
Akhavan-Niaki, H.2
McGowan, C.H.3
Russell, P.4
-
63
-
-
0029054163
-
Differential expression and regulation of hsp70 and hsp90 by phorbol esters and heat shock
-
Jacquier-Sarlin, M.R.; Jornot, L.; Polla, B.S. Differential expression and regulation of hsp70 and hsp90 by phorbol esters and heat shock. J. Biol. Chem. 1995, 270, 14094-14099.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14094-14099
-
-
Jacquier-Sarlin, M.R.1
Jornot, L.2
Polla, B.S.3
-
64
-
-
32044436263
-
Hsp90: A chaperone for protein folding and gene regulation
-
Zhao, R.; Houry, W.A. Hsp90: A chaperone for protein folding and gene regulation. Biochem. Cell. Biol. 2005, 83, 703-710.
-
(2005)
Biochem. Cell. Biol.
, vol.83
, pp. 703-710
-
-
Zhao, R.1
Houry, W.A.2
-
65
-
-
17044387386
-
Hsp70 chaperones: Cellular functions and molecular mechanism
-
Mayer, M.P.; Bukau, B. Hsp70 chaperones: Cellular functions and molecular mechanism. Cell. Mol. Life Sci. 2007, 62, 670-684.
-
(2007)
Cell. Mol. Life Sci.
, vol.62
, pp. 670-684
-
-
Mayer, M.P.1
Bukau, B.2
-
66
-
-
27944436648
-
Structural basis of interdomain communication in the Hsc70 chaperone
-
Jiang, J.; Prasad, K.; Lafer, E.M.; Sousa, R. Structural basis of interdomain communication in the Hsc70 chaperone. Mol. Cell 2005, 20, 513-524.
-
(2005)
Mol. Cell
, vol.20
, pp. 513-524
-
-
Jiang, J.1
Prasad, K.2
Lafer, E.M.3
Sousa, R.4
-
67
-
-
0034646511
-
Structure of TPR domain-peptide complexes: Critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine
-
Scheufler, C.; Brinker, A.; Bourenkov, G.; Pegoraro, S.; Moroder, L.; Bartunik, H.; Hartl, F.U.; Moarefi, I. Structure of TPR domain-peptide complexes: Critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell 2000, 101, 199-210.
-
(2000)
Cell
, vol.101
, pp. 199-210
-
-
Scheufler, C.1
Brinker, A.2
Bourenkov, G.3
Pegoraro, S.4
Moroder, L.5
Bartunik, H.6
Hartl, F.U.7
Moarefi, I.8
-
68
-
-
0029564954
-
Heat shock transcription factors: Structure and regulation
-
Wu, C. Heat shock transcription factors: Structure and regulation. Annu. Rev. Cell Dev. Biol. 1995, 11, 441-469.
-
(1995)
Annu. Rev. Cell Dev. Biol.
, vol.11
, pp. 441-469
-
-
Wu, C.1
-
69
-
-
0032535245
-
Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
Morimoto, R.I. Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Develop. 1998, 12, 3788-3796. .
-
(1998)
Genes Develop.
, vol.12
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
70
-
-
17744372861
-
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
-
Pirkkala, L.; Nykanen, P.; Sistonen, L. Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J. 2001, 15, 1118-1131.
-
(2001)
FASEB J.
, vol.15
, pp. 1118-1131
-
-
Pirkkala, L.1
Nykanen, P.2
Sistonen, L.3
-
71
-
-
84934443868
-
Heat shock factor 1 as a coordinator of stress and developmental pathways
-
Anckar, J.; Sistonen, L. Heat shock factor 1 as a coordinator of stress and developmental pathways. Adv. Exp. Med. Biol. 2007, 594, 78-88.
-
(2007)
Adv. Exp. Med. Biol.
, vol.594
, pp. 78-88
-
-
Anckar, J.1
Sistonen, L.2
-
72
-
-
0032571397
-
Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis
-
McMillan, D.R.; Xiao, X.; Shao, L.; Graves, K.; Benjamin, I.J. Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis. J. Biol. Chem. 1998, 273, 7523-7528.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7523-7528
-
-
McMillan, D.R.1
Xiao, X.2
Shao, L.3
Graves, K.4
Benjamin, I.J.5
-
73
-
-
0026746491
-
Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells
-
Sistonen, L.; Sarge, K.D.; Phillips, B.; Abravaya, K.; Morimoto, R.I. Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells. Mol. Cell. Biol. 1992, 12, 4104-4111.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 4104-4111
-
-
Sistonen, L.1
Sarge, K.D.2
Phillips, B.3
Abravaya, K.4
Morimoto, R.I.5
-
74
-
-
18544383003
-
Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract
-
Bu, L.; Jin, Y.; Shi, Y.; Chu, R.; Ban, A.; Eiberg, H.; Andres, L.; Jiang, H.; Zheng, G.; Qian, M. Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract. Nat. Genet. 2002, 31, 276-278.
-
(2002)
Nat. Genet.
, vol.31
, pp. 276-278
-
-
Bu, L.1
Jin, Y.2
Shi, Y.3
Chu, R.4
Ban, A.5
Eiberg, H.6
Andres, L.7
Jiang, H.8
Zheng, G.9
Qian, M.10
-
75
-
-
18444415138
-
Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice
-
Kallio, M.; Chang, Y.; Manuel, M.; Alastalo, T.P.; Rallu, M.; Gitton, Y.; Pirkkala, L.; Loones, M.T.; Paslaru, L.; Larney, S. Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice. EMBO J. 2002, 21, 2591-2601.
-
(2002)
EMBO J.
, vol.21
, pp. 2591-2601
-
-
Kallio, M.1
Chang, Y.2
Manuel, M.3
Alastalo, T.P.4
Rallu, M.5
Gitton, Y.6
Pirkkala, L.7
Loones, M.T.8
Paslaru, L.9
Larney, S.10
-
76
-
-
0026665975
-
The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression
-
Abravaya, K.; Myers, M.P.; Murphy, S.P.; Morimoto, R.I. The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression. Genes Develop. 1992, 6, 1153-1164.
-
(1992)
Genes Develop.
, vol.6
, pp. 1153-1164
-
-
Abravaya, K.1
Myers, M.P.2
Murphy, S.P.3
Morimoto, R.I.4
-
77
-
-
0032031725
-
Molecular chaperones as HSF1-specific transcriptional repressors
-
Shi, Y.; Mosser, D.D.; Morimoto, R.I. Molecular chaperones as HSF1-specific transcriptional repressors. Genes Develop. 1998, 12, 654-666.
-
(1998)
Genes Develop.
, vol.12
, pp. 654-666
-
-
Shi, Y.1
Mosser, D.D.2
Morimoto, R.I.3
-
78
-
-
0032555685
-
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
-
Zou, J.; Guo, Y.; Guettouche, T.; Smith, D.F.; Voellmy, R. Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1. Cell 1998, 94, 471-480.
-
(1998)
Cell
, vol.94
, pp. 471-480
-
-
Zou, J.1
Guo, Y.2
Guettouche, T.3
Smith, D.F.4
Voellmy, R.5
-
79
-
-
0024852809
-
Trimerization of a yeast transcriptional activator via a coiled-coil motif
-
Sorger, P.K.; Nelson, H.C. Trimerization of a yeast transcriptional activator via a coiled-coil motif. Cell 1989, 59, 807-813.
-
(1989)
Cell
, vol.59
, pp. 807-813
-
-
Sorger, P.K.1
Nelson, H.C.2
-
80
-
-
0034175631
-
P-TEFb kinase recruitment and function at heat shock loci
-
Lis, J.T.; Mason, P.; Peng, J.; Price, D.H.; Werner, J. P-TEFb kinase recruitment and function at heat shock loci. Genes Develop. 2000, 14, 792-803.
-
(2000)
Genes Develop.
, vol.14
, pp. 792-803
-
-
Lis, J.T.1
Mason, P.2
Peng, J.3
Price, D.H.4
Werner, J.5
-
81
-
-
0024282785
-
Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation
-
Sorger, P.K.; Pelham, H.R. Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation. Cell 1988, 54, 855-864.
-
(1988)
Cell
, vol.54
, pp. 855-864
-
-
Sorger, P.K.1
Pelham, H.R.2
-
82
-
-
0029804194
-
Repression of human heat shock factor 1 activity at control temperature by phosphorylation
-
Knauf, U.; Newton, E.M.; Kyriakis, J.; Kingston, R.E. Repression of human heat shock factor 1 activity at control temperature by phosphorylation. Genes Develop. 1996, 10, 2782-2793.
-
(1996)
Genes Develop.
, vol.10
, pp. 2782-2793
-
-
Knauf, U.1
Newton, E.M.2
Kyriakis, J.3
Kingston, R.E.4
-
83
-
-
0030988941
-
Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation
-
Kline, M.P.; Morimoto, R.I. Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation. Mol. Cell. Biol. 1997, 17, 2107-2115.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2107-2115
-
-
Kline, M.P.1
Morimoto, R.I.2
-
84
-
-
31344444419
-
Inhibition of DNA binding by differential sumoylation of heat shock factors
-
Anckar, J.; Hietakangas, V.; Denessiouk, K.; Thiele, D.J.; Johnson, M.S.; Sistonen, L. Inhibition of DNA binding by differential sumoylation of heat shock factors. Mol. Cell. Biol. 2006, 26, 955-964.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 955-964
-
-
Anckar, J.1
Hietakangas, V.2
Denessiouk, K.3
Thiele, D.J.4
Johnson, M.S.5
Sistonen, L.6
-
85
-
-
25444520537
-
MiR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino, A.; Calin, G.A. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. USA 2005, 102, 13944-13949.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
-
86
-
-
33745084520
-
PI3K signaling and miRNA expression during the response of quiescent human fibroblasts to distinct proliferative stimuli
-
Gu, J.; Iyer, V.R. PI3K signaling and miRNA expression during the response of quiescent human fibroblasts to distinct proliferative stimuli. Genome Biol. 2006, 7, R42.
-
(2006)
Genome Biol.
, vol.7
-
-
Gu, J.1
Iyer, V.R.2
-
88
-
-
43049101535
-
MiRNA modulation of the cellular stress response
-
Babar, I.A.; Slack F.J. miRNA modulation of the cellular stress response. Future Oncol. 2008, 4, 289-298.
-
(2008)
Future Oncol.
, vol.4
, pp. 289-298
-
-
Babar, I.A.1
Slack, F.J.2
-
90
-
-
78149465947
-
Identification of microRNAs associated with hyperthermia-induced cellular stress response
-
DOI: 10.1007/s12192-010-0189-7
-
Wilmink, G.J.; Roth, C.L.; Ibey,B.L.; Ketchum, N.; Bernhard, J.; Cerna, C.Z.; Roach, W.P. Identification of microRNAs associated with hyperthermia-induced cellular stress response. Cell Stress Chaperones 2010, DOI: 10.1007/s12192-010-0189-7.
-
(2010)
Cell Stress Chaperones
-
-
Wilmink, G.J.1
Roth C.L.2
, IbeyB.L.3
Ketchum, N.4
Bernhard, J.5
Cerna, C.Z.6
Roach, W.P.7
-
91
-
-
0027220168
-
Heat Shock in Escherichia coli increases binding of dnaK (the hsp70 homolog) to polypeptides by promoting its phosphorylation
-
Sherman, M.Y.; Goldberg, A.L. Heat Shock in Escherichia coli increases binding of dnaK (the hsp70 homolog) to polypeptides by promoting its phosphorylation. Proc. Natl. Acad. Sci. USA 1993, 90, 8648-8652.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8648-8652
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
92
-
-
0028075838
-
Heat shock-induced phosphorylation of GroEL alters its binding and dissociation from unfolded proteins
-
Sherman, M.; Goldberg, A.L. Heat shock-induced phosphorylation of GroEL alters its binding and dissociation from unfolded proteins. J. Biol. Chem. 1994, 269, 31479-31483.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31479-31483
-
-
Sherman, M.1
Goldberg, A.L.2
-
93
-
-
0026519887
-
Heat shock in Escherichia coli alters the protein-binding properties of the chaperonin groEL by inducing its phosphorylation
-
Sherman, M.Y.; Goldberg, A.L. Heat shock in Escherichia coli alters the protein-binding properties of the chaperonin groEL by inducing its phosphorylation. Nature 1992, 357, 167-169.
-
(1992)
Nature
, vol.357
, pp. 167-169
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
94
-
-
20844444338
-
S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities
-
Martínez-Ruiz, A.; Villanueva, L.; González de Orduña, C.; López-Ferrer, D.; Higueras, M.A.; Tarín, C.; Rodríguez-Crespo, I.; Vázquez, J.; Lamas, S. S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities. Proc. Natl. Acad. Sci. USA 2005, 102, 8525-8530.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 8525-8530
-
-
Martínez-Ruiz, A.1
Villanueva, L.2
González De Orduna, C.3
López-Ferrer, D.4
Higueras, M.A.5
Tarín, C.6
Rodríguez-Crespo, I.7
Vázquez, J.8
Lamas, S.9
-
95
-
-
0033524938
-
Chaperone activity with a redox switch
-
Jakob, U.; Muse, W.; Eser, M.; Bardwell, J.C. Chaperone activity with a redox switch. Cell 1999, 96, 341-352.
-
(1999)
Cell
, vol.96
, pp. 341-352
-
-
Jakob, U.1
Muse, W.2
Eser, M.3
Bardwell, J.C.4
-
96
-
-
11444262208
-
Beyond transcription-new mechanisms for the regulation of molecular chaperones
-
Winter, J.; Jakob, U. Beyond transcription-new mechanisms for the regulation of molecular chaperones. Crit. Rev. Biochem. Mol. Biol. 2004, 39, 297-317.
-
(2004)
Crit. Rev. Biochem. Mol. Biol.
, vol.39
, pp. 297-317
-
-
Winter, J.1
Jakob, U.2
-
98
-
-
31444442284
-
Substrate binding to the molecular chaperone Hsp104 and its regulation by nucleotides
-
Bosl, B.; Grimminger, B.; Walter S. Substrate binding to the molecular chaperone Hsp104 and its regulation by nucleotides. J. Biol. Chem. 2005, 280, 38170-38176.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38170-38176
-
-
Bosl, B.1
Grimminger, B.2
Walter, S.3
-
99
-
-
0027426041
-
ATP-induced protein-Hsp70 complex dissociation requires K+ but not ATP hydrolysis
-
Palleros, D.R.; Reid, K.L.; Shi, L.; William, J.W.; Anthony, L.F. ATP-induced protein-Hsp70 complex dissociation requires K+ but not ATP hydrolysis. Nature 1993, 365, 664-666.
-
(1993)
Nature
, vol.365
, pp. 664-666
-
-
Palleros, D.R.1
Reid, K.L.2
Shi, L.3
William, J.W.4
Anthony, L.F.5
-
100
-
-
0030592538
-
The chaperonin ATPase cycle: Mechanism of allosteric switching and movements of substrate-binding domains in GroEL
-
Roseman, A.M.; Chen, S.; White, H.; Braig, K.; Saibil, H.R. The chaperonin ATPase cycle: Mechanism of allosteric switching and movements of substrate-binding domains in GroEL. Cell 1996, 87, 241-251.
-
(1996)
Cell
, vol.87
, pp. 241-251
-
-
Roseman, A.M.1
Chen, S.2
White, H.3
Braig, K.4
Saibil, H.R.5
-
101
-
-
11844276669
-
Functional specificity of co-chaperone interactions with Hsp90 client proteins
-
Riggs, D.L.; Cox, M.B.; Cheung-Flynn, J.; Prapapanich, V.; Carrigan, P.E.; Smith, D.F. Functional specificity of co-chaperone interactions with Hsp90 client proteins. Crit. Rev. Biochem. Mol Biol. 2004, 39, 279-295.
-
(2004)
Crit. Rev. Biochem. Mol Biol.
, vol.39
, pp. 279-295
-
-
Riggs, D.L.1
Cox, M.B.2
Cheung-Flynn, J.3
Prapapanich, V.4
Carrigan, P.E.5
Smith, D.F.6
-
102
-
-
35548939457
-
Heat shock proteins and protection of the nervous system
-
Brown, I.R. Heat shock proteins and protection of the nervous system. Ann. N. Y. Acad. Sci. 2007, 1113, 147-158.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1113
, pp. 147-158
-
-
Brown, I.R.1
-
103
-
-
33745167938
-
Protein-misfolding diseases and chaperone-based therapeutic approaches
-
Chaudhuri, T.K.; Paul, S. Protein-misfolding diseases and chaperone-based therapeutic approaches. FEBS J. 2006, 273, 1331-1349.
-
(2006)
FEBS J.
, vol.273
, pp. 1331-1349
-
-
Chaudhuri, T.K.1
Paul, S.2
-
104
-
-
7944233158
-
Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
-
Selkoe, D.J. Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases. Nat. Cell Biol. 2004, 6, 1054-1061.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 1054-1061
-
-
Selkoe, D.J.1
-
105
-
-
7044238416
-
Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
-
Forman, M.S.; Trojanowski, J.Q.; Lee, V.M. Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs. Nat. Med. 2004, 10, 1055-1063.
-
(2004)
Nat. Med.
, vol.10
, pp. 1055-1063
-
-
Forman, M.S.1
Trojanowski, J.Q.2
Lee, V.M.3
-
106
-
-
11144243412
-
Modulation of neurodegeneration by molecular chaperones
-
Muchowski, P.J.; Wacker, J.L. Modulation of neurodegeneration by molecular chaperones. Nat. Rev. Neurosci. 2005, 6, 11-22.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 11-22
-
-
Muchowski, P.J.1
Wacker, J.L.2
-
107
-
-
34250899962
-
Neuronal expression of constitutive heat shock proteins: Implications for neurodegenerative diseases
-
Chen, S.; Brown, I.R. Neuronal expression of constitutive heat shock proteins: Implications for neurodegenerative diseases. Cell Stress Chaperones 2007, 12, 51-58.
-
(2007)
Cell Stress Chaperones
, vol.12
, pp. 51-58
-
-
Chen, S.1
Brown, I.R.2
-
108
-
-
0037501731
-
Update on parkinson disease
-
Siderowf, A.; Stern, M. Update on Parkinson Disease. Ann. Intern. Med. 2003, 138, 651-658.
-
(2003)
Ann. Intern. Med.
, vol.138
, pp. 651-658
-
-
Siderowf, A.1
Stern, M.2
-
109
-
-
0038689039
-
Protein aggregation and the ubiquitin proteasome pathway: Gaining the upper hand on neurodegeneration
-
Berke, S.J.; Paulson, H.L. Protein aggregation and the ubiquitin proteasome pathway: Gaining the upper hand on neurodegeneration. Curr. Opin. Genet. Develop. 2003, 13, 253-261.
-
(2003)
Curr. Opin. Genet. Develop.
, vol.13
, pp. 253-261
-
-
Berke, S.J.1
Paulson, H.L.2
-
110
-
-
0036846119
-
TorsinA and heat shock proteins act as molecular chaperones: Suppression of alphasynuclein aggregation
-
McLean, P.J.; Kawamata, H.; Shariff, S.; Hewett, J.; Sharma, N.; Ueda, K.; Breakefield, X.O.; Hyman, B.T. TorsinA and heat shock proteins act as molecular chaperones: Suppression of alphasynuclein aggregation. J. Neurochem. 2002, 83, 846-854.
-
(2002)
J. Neurochem.
, vol.83
, pp. 846-854
-
-
McLean, P.J.1
Kawamata, H.2
Shariff, S.3
Hewett, J.4
Sharma, N.5
Ueda, K.6
Breakefield, X.O.7
Hyman, B.T.8
-
111
-
-
17644383748
-
Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species
-
Dedmon, M.M.; Christodoulou, J.; Wilson, M.R.; Dobson, C.M. Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species. J. Biol. Chem. 2005, 280, 14733-14740.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14733-14740
-
-
Dedmon, M.M.1
Christodoulou, J.2
Wilson, M.R.3
Dobson, C.M.4
-
112
-
-
0742306066
-
Mutant genes responsible for Parkinson's disease
-
Le, W.; Appel, S.H. Mutant genes responsible for Parkinson's disease. Curr. Opin. Pharmacol. 2004, 4, 79-84.
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, pp. 79-84
-
-
Le, W.1
Appel, S.H.2
-
113
-
-
25444514752
-
Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress
-
Li, H.M.; Niki, T.; Taira, T.; Iguchi-Ariga, S.M.; Ariga, H. Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress. Free Radical Res. 2005, 39, 1091-1099.
-
(2005)
Free Radical Res.
, vol.39
, pp. 1091-1099
-
-
Li, H.M.1
Niki, T.2
Taira, T.3
Iguchi-Ariga, S.M.4
Ariga, H.5
-
114
-
-
23344432914
-
Role of molecular chaperones in neurodegenerative disorders
-
Meriin, A.B.; Sherman, M.Y. Role of molecular chaperones in neurodegenerative disorders. Int. J. Hyperther. 2005, 21, 403-419.
-
(2005)
Int. J. Hyperther.
, vol.21
, pp. 403-419
-
-
Meriin, A.B.1
Sherman, M.Y.2
-
115
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck, P.K.; Chan, H.Y.; Trojanowski, J.Q.; Lee, V.M.; Bonini, N.M. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 2002, 295, 865-868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
116
-
-
0038159253
-
Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function
-
Tsai, Y.C.; Fishman, P.S.; Thakor, N.V.; Oyler, G.A. Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function. J. Biol. Chem. 2003, 278, 22044-22055.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22044-22055
-
-
Tsai, Y.C.1
Fishman, P.S.2
Thakor, N.V.3
Oyler, G.A.4
-
117
-
-
28844451001
-
Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice
-
Shen, H.Y.; He, J.C.; Wang, Y.; Huang, Q.Y.; Chen, J.F. Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice. J. Biol. Chem. 2005, 280, 39962-39969.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39962-39969
-
-
Shen, H.Y.1
He, J.C.2
Wang, Y.3
Huang, Q.Y.4
Chen, J.F.5
-
118
-
-
0037052684
-
Immobilization stress induces the expression of alphaBcrystallin in rat hippocampus: Implications of glial activation in stress-mediated hippocampal degeneration
-
Yun, S.J.; Hahm, D.H.; Lee, E.H. Immobilization stress induces the expression of alphaBcrystallin in rat hippocampus: Implications of glial activation in stress-mediated hippocampal degeneration. Neurosci. Lett. 2002, 324, 45-48.
-
(2002)
Neurosci. Lett.
, vol.324
, pp. 45-48
-
-
Yun, S.J.1
Hahm, D.H.2
Lee, E.H.3
-
119
-
-
3242770627
-
Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: Effects on amyloid fibril formation and chaperone activity
-
Rekas, A.; Adda, C.G.; Andrew, A.J.; Barnham, K.J.; Sunde, M.; Galatis, D.; Williamson, N.A.; Masters, C.L.; Anders, R.F.; Robinson, C.V.; Cappai, R.; Carver, J.A. Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: Effects on amyloid fibril formation and chaperone activity. J. Mol. Biol. 2004, 340, 1167-1183.
-
(2004)
J. Mol. Biol.
, vol.340
, pp. 1167-1183
-
-
Rekas, A.1
Adda, C.G.2
Andrew, A.J.3
Barnham, K.J.4
Sunde, M.5
Galatis, D.6
Williamson, N.A.7
Masters, C.L.8
Anders, R.F.9
Robinson, C.V.10
Cappai, R.11
Carver, J.A.12
-
120
-
-
33644640684
-
Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies
-
Uryu, K.; Richter-Landsberg, C.; Welch, W.; Sun, E.; Goldbaum, O.; Norris, E.H.; Pham, C.T.; Yazawa, I. Hilburger, K.; Micsenyi, M.; Giasson, B.I.; Bonini, N.M.; Lee, V.M.; Trojanowski, J.Q. Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies. Am. J. Pathol. 2006, 168, 947-961.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 947-961
-
-
Uryu, K.1
Richter-Landsberg, C.2
Welch, W.3
Sun, E.4
Goldbaum, O.5
Norris, E.H.6
Pham, C.T.7
Yazawa, I.8
Hilburger, K.9
Micsenyi, M.10
Giasson, B.I.11
Bonini, N.M.12
Lee, V.M.13
Trojanowski, J.Q.14
-
121
-
-
0003159315
-
-
Enna, S.J., Coyle, J.T., Eds.; McGraw-Hill Health Professions Division: NewYork, NY, USA
-
Davis, K.L.; Samuels, S.C. Pharmacological Management of Neurological and Psychiatric Disorders; Enna, S.J., Coyle, J.T., Eds.; McGraw-Hill Health Professions Division: NewYork, NY, USA, 1998; pp. 267-316.
-
(1998)
Pharmacological Management of Neurological and Psychiatric Disorders
, pp. 267-316
-
-
Davis, K.L.1
Samuels, S.C.2
-
122
-
-
33847339301
-
NSAIDs and Alzheimer's disease: Epidemiological, animal model and clinical studies
-
McGeer, P.L.; McGeer, E. NSAIDs and Alzheimer's disease: Epidemiological, animal model and clinical studies. Neurobiol. Aging 2007, 28, 639-647
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 639-647
-
-
McGeer, P.L.1
McGeer, E.2
-
123
-
-
0032585829
-
Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease
-
Yoo, B.C.; Seidl, R.; Cairns, N.; Lubec, G. Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease. J Neural Transmission Suppl. 1999, 57, 315-322.
-
(1999)
J Neural Transmission Suppl.
, vol.57
, pp. 315-322
-
-
Yoo, B.C.1
Seidl, R.2
Cairns, N.3
Lubec, G.4
-
124
-
-
0028297910
-
Expression of small heat-shock protein hsp 27 in reactive gliosis in Alzheimer disease and other types of dementia
-
Renkawek, K.; Bosman, G.J.; de Jong, W.W. Expression of small heat-shock protein hsp 27 in reactive gliosis in Alzheimer disease and other types of dementia. Acta Neuropathol. 1994, 87, 511-519.
-
(1994)
Acta Neuropathol.
, vol.87
, pp. 511-519
-
-
Renkawek, K.1
Bosman, G.J.2
De Jong, W.W.3
-
125
-
-
0032475957
-
The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion
-
Yang, Y.; Turner, R.S.; Gaut, J.R. The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion. J. Biol. Chem. 1998, 273, 25552-25555.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25552-25555
-
-
Yang, Y.1
Turner, R.S.2
Gaut, J.R.3
-
126
-
-
33845918172
-
Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro
-
Evans, C.G.; Wisén, S.; Gestwicki, J.E. Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro. J. Biol. Chem. 2006, 281, 33182-33191.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 33182-33191
-
-
Evans, C.G.1
Wisén, S.2
Gestwicki, J.E.3
-
127
-
-
33644960735
-
Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains
-
Wilhelmus, M.M.; Otte-Höller, I.; Wesseling, P.; de Waal, R.M.; Boelens, W.C.; Verbeek, M.M. Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains. Neuropathol. Appl. Neurobiol. 2006, 32, 119-130.
-
(2006)
Neuropathol. Appl. Neurobiol.
, vol.32
, pp. 119-130
-
-
Wilhelmus, M.M.1
Otte-Höller, I.2
Wesseling, P.3
De Waal, R.M.4
Boelens, W.C.5
Verbeek, M.M.6
-
128
-
-
38149110518
-
Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein
-
Fonte, V.; Kipp, D.R.; Yerg, J.; Merin, D.; Forrestal, M.; Wagner, E.; Roberts, C.M.; Link, C.D. Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein. J. Biol. Chem. 2008, 283, 784-791.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 784-791
-
-
Fonte, V.1
Kipp, D.R.2
Yerg, J.3
Merin, D.4
Forrestal, M.5
Wagner, E.6
Roberts, C.M.7
Link, C.D.8
-
129
-
-
11144356089
-
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
-
Petrucelli, L.; Dickson, D.; Kehoe, K.; Taylor, J.; Snyder, H.; Grover, A.; De Lucia, M.; McGowan, E.; Lewis, J.; Prihar, G.; Kim, J.; Dillmann, W.H.; Browne, S.E.; Hall, A.; Voellmy, R.; Tsuboi, Y.; Dawson, T.M.; Wolozin, B.; Hardy, J.; Hutton, M. CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Hum. Mol. Genet. 2004, 13, 703-714.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 703-714
-
-
Petrucelli, L.1
Dickson, D.2
Kehoe, K.3
Taylor, J.4
Snyder, H.5
Grover, A.6
De Lucia, M.7
McGowan, E.8
Lewis, J.9
Prihar, G.10
Kim, J.11
Dillmann, W.H.12
Browne, S.E.13
Hall, A.14
Voellmy, R.15
Tsuboi, Y.16
Dawson, T.M.17
Wolozin, B.18
Hardy, J.19
Hutton, M.20
more..
-
130
-
-
2342444942
-
Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival
-
Shimura, H.; Miura-Shimura, Y.; Kosik, K.S. Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival. J. Biol. Chem. 2004, 279, 17957-17962.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 17957-17962
-
-
Shimura, H.1
Miura-Shimura, Y.2
Kosik, K.S.3
-
131
-
-
0037457966
-
Chaperones increase association of tau protein with microtubules
-
Dou, F.; Netzer, W.J.; Tanemura, K.; Li, F.; Hartl, F.U.; Takashima, A.; Gouras, G.K.; Greengard, P.; Xu, H. Chaperones increase association of tau protein with microtubules. Proc. Natl. Acad. Sci. USA 2003, 100, 721-726.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 721-726
-
-
Dou, F.1
Netzer, W.J.2
Tanemura, K.3
Li, F.4
Hartl, F.U.5
Takashima, A.6
Gouras, G.K.7
Greengard, P.8
Xu, H.9
-
132
-
-
69949170793
-
The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies
-
Bauer, P.O.; Nukina, N. The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies. J. Neurochem. 2009, 110, 1737-1765.
-
(2009)
J. Neurochem.
, vol.110
, pp. 1737-1765
-
-
Bauer, P.O.1
Nukina, N.2
-
133
-
-
0033499931
-
Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease
-
Chai, Y.; Koppenhafer, S.L.; Bonini, N.M.; Paulson, H.L. Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease. J. Neurosci. 1999, 19, 10338-10347
-
(1999)
J. Neurosci.
, vol.19
, pp. 10338-10347
-
-
Chai, Y.1
Koppenhafer, S.L.2
Bonini, N.M.3
Paulson, H.L.4
-
134
-
-
0034641589
-
Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: Their role in suppression of aggregation and cellular toxicity
-
Jana, N.R.; Tanaka, M.; Wang, G.; Nukina, N. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: Their role in suppression of aggregation and cellular toxicity. Hum. Mol. Genet. 2000, 9, 2009-2018.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2009-2018
-
-
Jana, N.R.1
Tanaka, M.2
Wang, G.3
Nukina, N.4
-
135
-
-
0036566675
-
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin
-
Wyttenbach, A.; Sauvageot, O.; Carmichael, J.; Diaz-Latoud, C.; Arrigo, A.P.; Rubinsztein, D.C. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. Hum. Mol. Genet. 2002, 11, 1137-1151.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1137-1151
-
-
Wyttenbach, A.1
Sauvageot, O.2
Carmichael, J.3
Diaz-Latoud, C.4
Arrigo, A.P.5
Rubinsztein, D.C.6
-
136
-
-
0034608868
-
Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils
-
Muchowski, P.J.; Schaffar, G.; Sittler, A.; Wanker, E.E.; Hayer-Hartl, M.K.; Hartl, F.U. Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils. Proc. Natl Acad. Sci. USA 2000, 97, 7841-7846.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 7841-7846
-
-
Muchowski, P.J.1
Schaffar, G.2
Sittler, A.3
Wanker, E.E.4
Hayer-Hartl, M.K.5
Hartl, F.U.6
-
137
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu, A.L.; Murphy, C.T.; Kenyon, C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 2003, 300, 1142-1145.
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
138
-
-
18544392423
-
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
-
Warrick, J.M.; Paulson, H.L.; Gray-Board, G.L.; Bui, Q.T.; Fischbeck, K.H.; Pittman, R.N.; Bonini, N.M. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell 1998, 93, 939-949.
-
(1998)
Cell
, vol.93
, pp. 939-949
-
-
Warrick, J.M.1
Paulson, H.L.2
Gray-Board, G.L.3
Bui, Q.T.4
Fischbeck, K.H.5
Pittman, R.N.6
Bonini, N.M.7
-
139
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
Gunawardena, S.; Her, L.S.; Brusch, R.G.; Laymon, R.A.; Niesman, I.R.; Gordesky-Gold, B., Sintasath, L.; Bonini, N.M.; Goldstein, L.S. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron 2003, 40, 25-40.
-
(2003)
Neuron
, vol.40
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.9
-
140
-
-
0035394668
-
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
-
Cummings, C.J.; Sun, Y.; Opal, P.; Antalffy, B.; Mestril, R.; Orr, H.T.; Dillmann, W.H.; Zoghbi, H.Y. Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum. Mol. Genet. 2001, 10, 1511-1518.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1511-1518
-
-
Cummings, C.J.1
Sun, Y.2
Opal, P.3
Antalffy, B.4
Mestril, R.5
Orr, H.T.6
Dillmann, W.H.7
Zoghbi, H.Y.8
-
141
-
-
84984763363
-
Mechanisms challenges and opportunities in stroke
-
Lo, E.H.; Dalkara, T.; Moskowitz, M.A. Mechanisms, challenges and opportunities in stroke. Nat. Rev. Neurosci. 2003, 4, 399-415.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 399-415
-
-
Lo, E.H.1
Dalkara, T.2
Moskowitz, M.A.3
-
142
-
-
77649126524
-
Heart disease and stroke statistics-2010 update: A report from the American heart association
-
Lloyd-Jones, D.; Adams, R.J.; Brown, T.M.; Carnethon, M.; Dai, S.; De Simone, G.; Ferguson, T.B.; Ford, E.; Furie, K.; Gillespie, C.; Go, A.; Greenlund, K.; Haase, N.; Hailpern, S.; Ho, P.M.; Howard, V.; Kissela, B.; Kittner, S.; Lackland, D.; Lisabeth, L.; Marelli, A.; McDermott, M.M.; Meigs, J.; Mozaffarian, D.; Mussolino, M.; Nichol, G.; Roger, V.L.; Rosamond, W.; Sacco, R.; Sorlie, P.; Thom, T.; Wasserthiel-Smoller, S.; Wong, N.D.; Wylie-Rosett, J. Heart disease and stroke statistics-2010 update: A report from the American Heart Association. Circulation 2010, 121, e46-e215.
-
(2010)
Circulation
, vol.121
-
-
Lloyd-Jones, D.1
Adams, R.J.2
Brown, T.M.3
Carnethon, M.4
Dai, S.5
De Simone, G.6
Ferguson, T.B.7
Ford, E.8
Furie, K.9
Gillespie, C.10
Go, A.11
Greenlund, K.12
Haase, N.13
Hailpern, S.14
Ho, P.M.15
Howard, V.16
Kissela, B.17
Kittner, S.18
Lackland, D.19
Lisabeth, L.20
Marelli, A.21
McDermott, M.M.22
Meigs, J.23
Mozaffarian, D.24
Mussolino, M.25
Nichol, G.26
Roger, V.L.27
Rosamond, W.28
Sacco, R.29
Sorlie, P.30
Thom, T.31
Wasserthiel-Smoller, S.32
Wong, N.D.33
Wylie-Rosett, J.34
more..
-
143
-
-
77955735802
-
Genetics and genomics of stroke: Novel approaches
-
Baird, A.E. Genetics and genomics of stroke: Novel approaches. J. Amer. Coll. Cardiol. 2010, 56, 245-253.
-
(2010)
J. Amer. Coll. Cardiol.
, vol.56
, pp. 245-253
-
-
Baird, A.E.1
-
144
-
-
0034963383
-
Protein aggregation after focal brain ischemia and reperfusion
-
Hu, B.R.; Janelidze, S.; Ginsberg, M.D.; Busto, R.; Perez-Pinzon, M.; Sick, T.J.; Siesjo, B.K.; Liu, C.L. Protein aggregation after focal brain ischemia and reperfusion. J. Cerebr. Blood Flow Metabol. 2001, 21, 865-875.
-
(2001)
J. Cerebr. Blood Flow Metabol.
, vol.21
, pp. 865-875
-
-
Hu, B.R.1
Janelidze, S.2
Ginsberg, M.D.3
Busto, R.4
Perez-Pinzon, M.5
Sick, T.J.6
Siesjo, B.K.7
Liu, C.L.8
-
145
-
-
0034192398
-
Protein aggregation after transient cerebral ischemia
-
Hu, B.R.; Martone, M.E.; Jones, Y.Z.; Liu, C.L. Protein aggregation after transient cerebral ischemia. J. Neurosci. 2000, 20, 3191-3199.
-
(2000)
J. Neurosci.
, vol.20
, pp. 3191-3199
-
-
Hu, B.R.1
Martone, M.E.2
Jones, Y.Z.3
Liu, C.L.4
-
146
-
-
0038354461
-
Shutdown of translation: Lethal or protective? Unfolded protein response versus apoptosis
-
Paschen, W. Shutdown of translation: Lethal or protective? Unfolded protein response versus apoptosis. J. Cerebr. Blood Flow Metabol. 2003, 23, 773-779.
-
(2003)
J. Cerebr. Blood Flow Metabol.
, vol.23
, pp. 773-779
-
-
Paschen, W.1
-
147
-
-
0035190132
-
Endoplasmic reticulum dysfunction-A common denominator for cell injury in acute and degenerative diseases of the brain?
-
Paschen, W.; Frandsen, A. Endoplasmic reticulum dysfunction-a common denominator for cell injury in acute and degenerative diseases of the brain? J. Neurochem. 2001, 79, 719-725.
-
(2001)
J. Neurochem.
, vol.79
, pp. 719-725
-
-
Paschen, W.1
Frandsen, A.2
-
148
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
Taylor, J.P.; Hardy, J.; Fischbeck, K.H. Toxic proteins in neurodegenerative disease. Science 2002, 296, 1991-1995.
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
149
-
-
7644234348
-
Molecular identification of the ischemic penumbra
-
Weinstein, P.R.; Hong, S.; Sharp, F.R. Molecular identification of the ischemic penumbra. Stroke 2004, 35, 2666-2670.
-
(2004)
Stroke
, vol.35
, pp. 2666-2670
-
-
Weinstein, P.R.1
Hong, S.2
Sharp, F.R.3
-
150
-
-
0027492357
-
Induction of 70- kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat
-
Kinouchi, H.; Sharp, F.R.; Hill, M.P.; Koistinaho, J.; Sagar, S.M.; Chan, P.H. Induction of 70- kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat. J. Cerebr. Blood Flow Metabol. 1993, 13, 105-115.
-
(1993)
J. Cerebr. Blood Flow Metabol.
, vol.13
, pp. 105-115
-
-
Kinouchi, H.1
Sharp, F.R.2
Hill, M.P.3
Koistinaho, J.4
Sagar, S.M.5
Chan, P.H.6
-
151
-
-
0034089551
-
Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction
-
Rajdev, S.; Hara, K.; Kokubo, Y.; Mestril, R.; Dillmann, W.; Weinstein, P.R.; Sharp, F.R. Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction. Ann. Neurol. 2000, 47, 782-791.
-
(2000)
Ann. Neurol.
, vol.47
, pp. 782-791
-
-
Rajdev, S.1
Hara, K.2
Kokubo, Y.3
Mestril, R.4
Dillmann, W.5
Weinstein, P.R.6
Sharp, F.R.7
-
152
-
-
0030765644
-
Transgenic mice expressing the human inducible Hsp70 have hippocampal neurons resistant to ischemic injury
-
Plumier, J.C.; Krueger, A.M.; Currie, R.W.; Kontoyiannis, D.; Kollias, G.; Pagoulatos, G.N. Transgenic mice expressing the human inducible Hsp70 have hippocampal neurons resistant to ischemic injury. Cell Stress Chaperones 1997, 2, 162-167.
-
(1997)
Cell Stress Chaperones
, vol.2
, pp. 162-167
-
-
Plumier, J.C.1
Krueger, A.M.2
Currie, R.W.3
Kontoyiannis, D.4
Kollias, G.5
Pagoulatos, G.N.6
-
153
-
-
0035200188
-
Overexpression of HSP72 after induction of experimental stroke protects neurons from ischemic damage
-
Hoehn, B.; Ringer, T.M.; Xu, L.; Giffard, R.G.; Sapolsky, R.M.; Steinberg, G.K.; Yenari, M.A. Overexpression of HSP72 after induction of experimental stroke protects neurons from ischemic damage. J. Cerebr. Blood Flow Metabol. 2001, 21, 1303-1309.
-
(2001)
J. Cerebr. Blood Flow Metabol.
, vol.21
, pp. 1303-1309
-
-
Hoehn, B.1
Ringer, T.M.2
Xu, L.3
Giffard, R.G.4
Sapolsky, R.M.5
Steinberg, G.K.6
Yenari, M.A.7
-
154
-
-
15644377983
-
Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy
-
Yenari, M.A.; Fink, S.L.; Sun, G.H.; Chang, L.K.; Patel, M.K.; Kunis, D.M.; Onley, D.; Ho, D.Y.; Sapolsky, R.M.; Steinberg, G.K. Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy. Ann. Neurol. 1998, 44, 584-591.
-
(1998)
Ann. Neurol.
, vol.44
, pp. 584-591
-
-
Yenari, M.A.1
Fink, S.L.2
Sun, G.H.3
Chang, L.K.4
Patel, M.K.5
Kunis, D.M.6
Onley, D.7
Ho, D.Y.8
Sapolsky, R.M.9
Steinberg, G.K.10
-
155
-
-
0032755381
-
The neuroprotective potential of heat shock protein 70 (HSP70)
-
Yenari, M.A.; Giffard, R.G.; Sapolsky, R.M.; Steinberg, G.K. The neuroprotective potential of heat shock protein 70 (HSP70). Mol. Med. Today 1999, 5, 525-531.
-
(1999)
Mol. Med. Today
, vol.5
, pp. 525-531
-
-
Yenari, M.A.1
Giffard, R.G.2
Sapolsky, R.M.3
Steinberg, G.K.4
-
156
-
-
33846703692
-
Pharmacological induction of heat shock protein exerts neuroprotective effects in experimental intracerebral hemorrhage
-
Sinn, D.I.; Chu, K.; Lee, S.T.; Song, E.C.; Jung, K.H.; Kim, E.H.; Park, D.K.; Kang, K.M.; Kim, M.; Roh, J.K. Pharmacological induction of heat shock protein exerts neuroprotective effects in experimental intracerebral hemorrhage. Brain Res. 2007, 1135, 167-176.
-
(2007)
Brain Res.
, vol.1135
, pp. 167-176
-
-
Sinn, D.I.1
Chu, K.2
Lee, S.T.3
Song, E.C.4
Jung, K.H.5
Kim, E.H.6
Park, D.K.7
Kang, K.M.8
Kim, M.9
Roh, J.K.10
-
157
-
-
29744466461
-
Antiapoptotic and antiinflammatory mechanisms of heat-shock protein protection
-
Yenari, M.A.; Liu, J.; Zheng, Z.; Vexler, Z.S.; Lee, J.E.; Giffard, R.G. Antiapoptotic and antiinflammatory mechanisms of heat-shock protein protection. Ann. N. Y. Acad. Sci. 2005, 1053, 74-83.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1053
, pp. 74-83
-
-
Yenari, M.A.1
Liu, J.2
Zheng, Z.3
Vexler, Z.S.4
Lee, J.E.5
Giffard, R.G.6
-
158
-
-
2342597809
-
Chaperones protein aggregation, and brain protection from hypoxic/ischemic injury
-
Giffard, R.G.; Xu, L.; Zhao, H.; Carrico, W.; Ouyang, Y.; Qiao, Y.; Sapolsky, R.; Steinberg, G.; Hu, B.; Yenari, M.A. Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury. J. Exp. Biol. 2004, 207, 3213-3220.
-
(2004)
J. Exp. Biol.
, vol.207
, pp. 3213-3220
-
-
Giffard, R.G.1
Xu, L.2
Zhao, H.3
Carrico, W.4
Ouyang, Y.5
Qiao, Y.6
Sapolsky, R.7
Steinberg, G.8
Hu, B.9
Yenari, M.A.10
-
159
-
-
70350537407
-
HSP27: Mechanisms of cellular protection against neuronal injury
-
Stetler, R.A.; Gao, Y.; Signore, A.P.; Cao, G.; Chen, J. HSP27: Mechanisms of cellular protection against neuronal injury. Curr. Mol. Med. 2009, 9, 863-872.
-
(2009)
Curr. Mol. Med.
, vol.9
, pp. 863-872
-
-
Stetler, R.A.1
Gao, Y.2
Signore, A.P.3
Cao, G.4
Chen, J.5
-
160
-
-
74049160362
-
Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway
-
Gao, Y.; Liang, W.; Hu, X.; Zhang, W.; Stetler, R.A.; Vosler, P.; Cao, G.; Chen, J. Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway. Stroke 2010, 41, 166-172.
-
(2010)
Stroke
, vol.41
, pp. 166-172
-
-
Gao, Y.1
Liang, W.2
Hu, X.3
Zhang, W.4
Stetler, R.A.5
Vosler, P.6
Cao, G.7
Chen, J.8
-
161
-
-
0141960161
-
Overexpression of HDJ-2 protects astrocytes from ischemia-like injury and reduces redistribution of ubiquitin staining in vitro
-
Qiao, Y.; Ouyang, Y.B.; Giffard, R.G. Overexpression of HDJ-2 protects astrocytes from ischemia-like injury and reduces redistribution of ubiquitin staining in vitro. J. Cerebr. Blood Flow Metabol. 2003, 23, 1113-1116.
-
(2003)
J. Cerebr. Blood Flow Metabol.
, vol.23
, pp. 1113-1116
-
-
Qiao, Y.1
Ouyang, Y.B.2
Giffard, R.G.3
-
162
-
-
38049170584
-
A molecular chaperone inducer protects neurons from ER stress
-
Kudo, T.; Kanemoto, S.; Hara, H.; Morimoto, N.; Morihara, T.; Kimura, R.; Tabira, T.; Imaizumi, K.; Takeda, M. A molecular chaperone inducer protects neurons from ER stress. Cell Death Differentiation 2008, 15, 364-375.
-
(2008)
Cell Death Differentiation
, vol.15
, pp. 364-375
-
-
Kudo, T.1
Kanemoto, S.2
Hara, H.3
Morimoto, N.4
Morihara, T.5
Kimura, R.6
Tabira, T.7
Imaizumi, K.8
Takeda, M.9
-
163
-
-
0035664213
-
Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues
-
Watanabe, M.; Dykes-Hoberg, M.; Culotta, V.C.; Price, D.L.; Wong, P.C.; Rothstein, J.D. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues. Neurobiol. Disease 2001, 8, 933-941.
-
(2001)
Neurobiol. Disease
, vol.8
, pp. 933-941
-
-
Watanabe, M.1
Dykes-Hoberg, M.2
Culotta, V.C.3
Price, D.L.4
Wong, P.C.5
Rothstein, J.D.6
-
164
-
-
0036241765
-
Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60
-
Hansen, J.J.; Dürr, A.; Cournu-Rebeix, I.; Georgopoulos, C.; Ang, D.; Nielsen, M.N.; Davoine, C.S.; Brice, A.; Fontaine, B.; Gregersen, N.; Bross, P. Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60. Am. J. Hum. Genet. 2002, 70, 1328-1332.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 1328-1332
-
-
Hansen, J.J.1
Dürr, A.2
Cournu-Rebeix, I.3
Georgopoulos, C.4
Ang, D.5
Nielsen, M.N.6
Davoine, C.S.7
Brice, A.8
Fontaine, B.9
Gregersen, N.10
Bross, P.11
-
165
-
-
0036267195
-
Hereditary spastic paraplegia: The pace quickens
-
Fink, J.K. Hereditary spastic paraplegia: The pace quickens. Ann. Neurol. 2002, 51, 669-672.
-
(2002)
Ann. Neurol.
, vol.51
, pp. 669-672
-
-
Fink, J.K.1
-
166
-
-
0034019637
-
Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome
-
Stone, D.L.; Slavotinek, A.; Bouffard, G.G.; Banerjee-Basu, S.; Baxevanis, A.D.; Barr, M.; Biesecker, L.G. Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome. Nat. Genet. 2000, 25, 79-82.
-
(2000)
Nat. Genet.
, vol.25
, pp. 79-82
-
-
Stone, D.L.1
Slavotinek, A.2
Bouffard, G.G.3
Banerjee-Basu, S.4
Baxevanis, A.D.5
Barr, M.6
Biesecker, L.G.7
-
167
-
-
0033812186
-
Mutations in MKKS cause Bardet-Biedl syndrome
-
Slavotinek, A.M.; Stone, E.M.; Mykytyn, K.; Heckenlively, J.R.; Green, J.S.; Heon, E.; Musarella, M.A.; Parfrey, P.S.; Sheffield, V.C.; Biesecker, L.G. Mutations in MKKS cause Bardet-Biedl syndrome. Nat. Genet. 2000, 26, 15-16.
-
(2000)
Nat. Genet.
, vol.26
, pp. 15-16
-
-
Slavotinek, A.M.1
Stone, E.M.2
Mykytyn, K.3
Heckenlively, J.R.4
Green, J.S.5
Heon, E.6
Musarella, M.A.7
Parfrey, P.S.8
Sheffield, V.C.9
Biesecker, L.G.10
-
168
-
-
0031934121
-
Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA
-
Litt, M.; Kramer, P.; LaMorticella, D.M.; Murphey, W.; Lovrien, E.W.; Weleber, R.G. Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA. Hum. Mol. Genet. 1998, 7, 471-474.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 471-474
-
-
Litt, M.1
Kramer, P.2
LaMorticella, D.M.3
Murphey, W.4
Lovrien, E.W.5
Weleber, R.G.6
-
169
-
-
17344361902
-
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy
-
Vicart, P.; Caron, A.; Guicheney, P.; Li, Z.; Prévost, M.C.; Faure, A.; Chateau, D.; Chapon, F.; Tomé, F.; Dupret, J.M.; Paulin, D.; Fardeau, M. A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat. Genet. 1998, 20, 92-95.
-
(1998)
Nat. Genet.
, vol.20
, pp. 92-95
-
-
Vicart, P.1
Caron, A.2
Guicheney, P.3
Li, Z.4
Prévost, M.C.5
Faure, A.6
Chateau, D.7
Chapon, F.8
Tomé, F.9
Dupret, J.M.10
Paulin, D.11
Fardeau, M.12
-
170
-
-
0030724879
-
AlphaB-crystallin interacts with intermediate filaments in response to stress
-
Djabali, K.; de Nechaud, B.; Landon, F.; Portier, M.M. AlphaB-crystallin interacts with intermediate filaments in response to stress. J. Cell Sci. 1997, 110, 2759-2769.
-
(1997)
J. Cell Sci.
, vol.110
, pp. 2759-2769
-
-
Djabali, K.1
De Nechaud, B.2
Landon, F.3
Portier, M.M.4
-
171
-
-
0036843239
-
Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome
-
Parvari, R.; Hershkovitz, E.; Grossman, N.; Gorodischer, R.; Loeys, B.; Zecic, A.; Mortier, G.; Gregory, S.; Sharony, R.; Kambouris, M.; Sakati, N.;
-
(2002)
Nat. Genet.
, vol.32
, pp. 448-452
-
-
Parvari, R.1
Hershkovitz, E.2
Grossman, N.3
Gorodischer, R.4
Loeys, B.5
Zecic, A.6
Mortier, G.7
Gregory, S.8
Sharony, R.9
Kambouris, M.10
Sakati, N.11
Meyer, B.F.12
Al Aqeel, A.I.13
Al Humaidan, A.K.14
Al Zanhrani, F.15
Al Swaid, A.16
Al Othman, J.17
Diaz, G.A.18
Weiner, R.19
Khan, K.T.S.20
Gordon, R.21
Gelb, B.D.22
more..
-
172
-
-
0343384355
-
ARSACS a spastic ataxia common in northeastern Quebec, is caused by mutations in a new gene encoding an 11.5-kb ORF
-
Engert, J.C.; Bérubé, P.; Mercier, J.; Doré, C.; Lepage, P.; Ge, B.; Bouchard, J.P.; Mathieu, J.; Melançon, S.B.; Schalling, M.; Lander, E.S.; Morgan, K.; Hudson, T.J.; Richter, A. ARSACS, a spastic ataxia common in northeastern Quebec, is caused by mutations in a new gene encoding an 11.5-kb ORF. Nat. Genet. 2000, 24, 120-125.
-
(2000)
Nat. Genet.
, vol.24
, pp. 120-125
-
-
Engert, J.C.1
Bérubé, P.2
Mercier, J.3
Doré, C.4
Lepage, P.5
Ge, B.6
Bouchard, J.P.7
Mathieu, J.8
Melançon, S.B.9
Schalling, M.10
Lander, E.S.11
Morgan, K.12
Hudson, T.J.13
Richter, A.14
-
173
-
-
36549002244
-
Sacsinopathies: Sacsin-related ataxia
-
Takiyama, Y. Sacsinopathies: Sacsin-related ataxia. Cerebellum 2007, 6, 353-359.
-
(2007)
Cerebellum
, vol.6
, pp. 353-359
-
-
Takiyama, Y.1
-
174
-
-
0019258079
-
Cultured animal-cells exposed to amino-acid-analogs or puromycin rapidly synthesize several polypeptides
-
Hightower, L.E. Cultured animal-cells exposed to amino-acid-analogs or puromycin rapidly synthesize several polypeptides. J. Cell. Physiol. 1980, 102, 407-427.
-
(1980)
J. Cell. Physiol.
, vol.102
, pp. 407-427
-
-
Hightower, L.E.1
-
175
-
-
0023181430
-
Induction of heat shock proteins in Chinese hamster ovary cells and development of thermotolerance by intermediate concentrations of puromycin
-
Lee, Y.J.; Dewey, W.C. Induction of heat shock proteins in Chinese hamster ovary cells and development of thermotolerance by intermediate concentrations of puromycin. J. Cell. Physiol. 1987, 132, 1-11.
-
(1987)
J. Cell. Physiol.
, vol.132
, pp. 1-11
-
-
Lee, Y.J.1
Dewey, W.C.2
-
176
-
-
0033669588
-
Formation of nuclear HSF1 granules varies depending on stress stimuli
-
Holmberg, C.I.; Illman, S.A.; Kallio, M.; Mikhailov, A.; Sistonen, L. Formation of nuclear HSF1 granules varies depending on stress stimuli. Cell Stress Chaperones 2000, 5, 219-228.
-
(2000)
Cell Stress Chaperones
, vol.5
, pp. 219-228
-
-
Holmberg, C.I.1
Illman, S.A.2
Kallio, M.3
Mikhailov, A.4
Sistonen, L.5
-
177
-
-
4143095430
-
Altered Hsp90 function in cancer: A unique therapeutic opportunity
-
Bagatell, R.; Whitesell, L. Altered Hsp90 function in cancer: A unique therapeutic opportunity. Mol. Cancer Ther. 2004, 3, 1021-1030.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1021-1030
-
-
Bagatell, R.1
Whitesell, L.2
-
178
-
-
0033890818
-
Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of Hsp90-binding agents
-
Bagatell, R.; Paine-Murrieta, G.D.; Taylor, C.W.; Pulcini, E.J.; Akinaga, S.; Benjamin, I.J.; Whitesell, L. Induction of a Heat Shock Factor 1-dependent Stress Response Alters the Cytotoxic Activity of Hsp90-binding Agents. Clin. Cancer Res. 2000, 6, 3312-3318.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3312-3318
-
-
Bagatell, R.1
Paine-Murrieta, G.D.2
Taylor, C.W.3
Pulcini, E.J.4
Akinaga, S.5
Benjamin, I.J.6
Whitesell, L.7
-
179
-
-
0035363805
-
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease
-
Sittler, A.; Lurz, R.; Lueder, G.; Priller, J.; Lehrach, H.; Hayer-Hartl, M.K.; Hartl, F.U.; Wanker, E.E. Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. Hum. Mol. Genet. 2001, 10, 1307-1315.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1307-1315
-
-
Sittler, A.1
Lurz, R.2
Lueder, G.3
Priller, J.4
Lehrach, H.5
Hayer-Hartl, M.K.6
Hartl, F.U.7
Wanker, E.E.8
-
180
-
-
3242695184
-
Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach
-
Hay, D.G.; Sathasivam, K.; Tobaben, S.; Stahl, B.; Marber, M.; Mestril, R.; Mahal, A.; Smith, D. L.; Woodman, B.; Bates, G.P. Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach. Hum. Mol. Genet. 2004, 13, 1389-1405.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1389-1405
-
-
Hay, D.G.1
Sathasivam, K.2
Tobaben, S.3
Stahl, B.4
Marber, M.5
Mestril, R.6
Mahal, A.7
Smith, D.L.8
Woodman, B.9
Bates, G.P.10
-
181
-
-
0037046554
-
Neurologists strike gold in drug screen effort
-
Abbott, A. Neurologists strike gold in drug screen effort. Nature 2002, 417, 109.
-
(2002)
Nature
, vol.417
, pp. 109
-
-
Abbott, A.1
-
182
-
-
0042170384
-
Bimoclomol a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1
-
Hargitai, J.; Lewis, H.; Boros, I.; Racz, T.; Fiser, A.; Kurucz, I.; Benjamin, I.; Vigh, L.; Penzes, Z.; Csermely, P.; Latchman, D.S. Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1. Biochem. Biophys. Res. Commun. 2003, 307, 689-695.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.307
, pp. 689-695
-
-
Hargitai, J.1
Lewis, H.2
Boros, I.3
Racz, T.4
Fiser, A.5
Kurucz, I.6
Benjamin, I.7
Vigh, L.8
Penzes, Z.9
Csermely, P.10
Latchman, D.S.11
-
183
-
-
20244367890
-
Bimoclomol: A nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects
-
Vigh, L.; Literati, P.N.; Horvath, I.; Torok, Z.; Balogh, G.; Glatz, A.; Kovacs, E.; Boros, I.; Ferdinandy, P.; Farkas, B.; Jaszlits, L.; Jednakovits, A.; Koranyi, L.; Maresca, B. Bimoclomol: A nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects. Nat. Med. 1997, 3, 1150-1154.
-
(1997)
Nat. Med.
, vol.3
, pp. 1150-1154
-
-
Vigh, L.1
Literati, P.N.2
Horvath, I.3
Torok, Z.4
Balogh, G.5
Glatz, A.6
Kovacs, E.7
Boros, I.8
Ferdinandy, P.9
Farkas, B.10
Jaszlits, L.11
Jednakovits, A.12
Koranyi, L.13
Maresca, B.14
-
184
-
-
1942486792
-
Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
-
Kieran, D.; Kalmar, B.; Dick, J.R.; Riddoch-Contreras, J.; Burnstock, G.; Greensmith, L. Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat. Med. 2004, 10, 402-405.
-
(2004)
Nat. Med.
, vol.10
, pp. 402-405
-
-
Kieran, D.1
Kalmar, B.2
Dick, J.R.3
Riddoch-Contreras, J.4
Burnstock, G.5
Greensmith, L.6
-
185
-
-
0027113344
-
Effect of sodium salicylate on the human heat shock response
-
Jurivich, D.A.; Sistonen, L.; Kroes, R.A.; Morimoto, R.I. Effect of sodium salicylate on the human heat shock response. Science 1992, 255, 1243-1245.
-
(1992)
Science
, vol.255
, pp. 1243-1245
-
-
Jurivich, D.A.1
Sistonen, L.2
Kroes, R.A.3
Morimoto, R.I.4
-
186
-
-
0035936004
-
Nonsteroidal antiinflammatory drugs and the risk of alzheimer's disease
-
Veld, B.A.; Ruitenberg, A.; Hofman, A.; Launer, L.J.; van Duijn, C.M.; Stijnen, T.; Breteler, M.M.; Stricker, B.H. Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease. N. Engl. J. Med. 2001, 345, 1515-1521.
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1515-1521
-
-
Veld, B.A.1
Ruitenberg, A.2
Hofman, A.3
Launer, L.J.4
Van Duijn., C.M.5
Stijnen., T.6
Breteler., M.M.7
Stricker, B.H.8
-
187
-
-
0028054926
-
The role of trehalose synthesis for the acquisition of thermotolerance in yeast. II. Physiological concentrations of trehalose increase the thermal stability of proteins in vitro
-
Hottiger, T.; De Virgilio, C.; Hall, M.N.; Boller, T.; Wiemken, A. The role of trehalose synthesis for the acquisition of thermotolerance in yeast. II. Physiological concentrations of trehalose increase the thermal stability of proteins in vitro. Eur. J. Biochem. 1994, 219, 187-193.
-
(1994)
Eur. J. Biochem.
, vol.219
, pp. 187-193
-
-
Hottiger, T.1
De Virgilio, C.2
Hall, M.N.3
Boller, T.4
Wiemken, A.5
-
188
-
-
0029832863
-
Chemical chaperones interfere with the formation of scrapie prion protein
-
Tatzelt, J.; Prusiner, S.B.; Welch, W.J. Chemical chaperones interfere with the formation of scrapie prion protein. EMBO J. 1996, 15, 6363-6373.
-
(1996)
EMBO J.
, vol.15
, pp. 6363-6373
-
-
Tatzelt, J.1
Prusiner, S.B.2
Welch, W.J.3
-
189
-
-
0023650350
-
Trehalose accumulates in Saccharomyces cerevisiae during exposure to agents that induce heat shock response
-
Attfield, P.V. Trehalose accumulates in Saccharomyces cerevisiae during exposure to agents that induce heat shock response. FEBS Lett. 1987, 225, 259-263.
-
(1987)
FEBS Lett.
, vol.225
, pp. 259-263
-
-
Attfield, P.V.1
-
190
-
-
0032039542
-
Multiple effects of trehalose on protein folding in vitro and in vivo
-
Singer, M.A.; Lindquist, S. Multiple effects of trehalose on protein folding in vitro and in vivo. Mol. Cell 1998, 1, 639-648.
-
(1998)
Mol. Cell
, vol.1
, pp. 639-648
-
-
Singer, M.A.1
Lindquist, S.2
-
191
-
-
1642633757
-
Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease
-
Tanaka, M.; Machida, Y.; Niu, S.; Ikeda, T.; Jana, N.R.; Doi, H.; Kurosawa, M.; Nekooki, M.; Nukina, N. Trehalose alleviates polyglutamine- mediated pathology in a mouse model of Huntington disease. Nature Med. 2004, 10, 148-154.
-
(2004)
Nature Med.
, vol.10
, pp. 148-154
-
-
Tanaka, M.1
Machida, Y.2
Niu, S.3
Ikeda, T.4
Jana, N.R.5
Doi, H.6
Kurosawa, M.7
Nekooki, M.8
Nukina, N.9
-
192
-
-
0345189365
-
Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein
-
Willingham, S.; Outeiro, T.F.; DeVit, M.J.; Lindquist, S.L.; Muchowski, P.J. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science 2003, 302, 1769-1772
-
(2003)
Science
, vol.302
, pp. 1769-1772
-
-
Willingham, S.1
Outeiro, T.F.2
DeVit, M.J.3
Lindquist, S.L.4
Muchowski, P.J.5
-
193
-
-
0031875042
-
The benzoquinone ansamycin 17-allylamino-17- demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin
-
Schulte, T.W.; Neckers, L.M. The benzoquinone ansamycin 17-allylamino-17- demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin. Cancer Chemother. Pharmacol. 1998, 42, 273-279.
-
(1998)
Cancer Chemother. Pharmacol.
, vol.42
, pp. 273-279
-
-
Schulte, T.W.1
Neckers, L.M.2
-
194
-
-
0141484615
-
A highaffinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
-
Kamal, A.; Thao, L.; Sensintaffar, J.; Zhang, L.; Boehm, M.F.; Fritz, L.C.; Burrows, F.J. A highaffinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 2003, 425, 407-410.
-
(2003)
Nature
, vol.425
, pp. 407-410
-
-
Kamal, A.1
Thao, L.2
Sensintaffar, J.3
Zhang, L.4
Boehm, M.F.5
Fritz, L.C.6
Burrows, F.J.7
-
195
-
-
4043112106
-
The induction of heat shock proteins as a potential strategy to treat neurodegenerative disorders
-
Klettner, A. The induction of heat shock proteins as a potential strategy to treat neurodegenerative disorders. Drug News Perspect. 2004, 17, 299-306.
-
(2004)
Drug News Perspect.
, vol.17
, pp. 299-306
-
-
Klettner, A.1
-
196
-
-
33744770333
-
Pharmacologic and genetic inhibition of Hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction
-
Thomas, M.; Harrell, J.M.; Morishima, Y.; Peng, H.M.; Pratt, W.B.; Lieberman, A.P. Pharmacologic and genetic inhibition of Hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction. .Hum. Mol. Genet. 2006, 15, 1876-1883.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1876-1883
-
-
Thomas, M.1
Harrell, J.M.2
Morishima, Y.3
Peng, H.M.4
Pratt, W.B.5
Lieberman, A.P.6
-
197
-
-
34547183507
-
Roles of heat shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies
-
Luo, W.; Dou, F.; Rodina, A.; Chip, S.; Kim, J.; Zhao, Q.; Moulick, K.; Aguirre, J.; Wu, N.; Greengard, P.; Chiosis, G. Roles of heat shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies. Proc. Natl. Acad. Sci. USA 2007, 104, 9511-9516.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 9511-9516
-
-
Luo, W.1
Dou, F.2
Rodina, A.3
Chip, S.4
Kim, J.5
Zhao, Q.6
Moulick, K.7
Aguirre, J.8
Wu, N.9
Greengard, P.10
Chiosis, G.11
-
198
-
-
27144503120
-
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration
-
Waza, M.; Adachi, H.; Katsuno, M.; Minamiyama, M.; Sang, C.; Tanaka, F.; Inukai, A.; Doyu, M.; Sobue, G. 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration. Nature Med. 2005, 11, 1088-1095.
-
(2005)
Nature Med.
, vol.11
, pp. 1088-1095
-
-
Waza, M.1
Adachi, H.2
Katsuno, M.3
Minamiyama, M.4
Sang, C.5
Tanaka, F.6
Inukai, A.7
Doyu, M.8
Sobue, G.9
-
199
-
-
27744436917
-
Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum
-
Dermaut, B.; Kumar-Singh, S.; Rademakers, R.; Theuns, J.; Cruts, M.; Van Broeckhoven, C. Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum. Trends Genet. 2005, 21, 664-672.
-
(2005)
Trends Genet.
, vol.21
, pp. 664-672
-
-
Dermaut, B.1
Kumar-Singh, S.2
Rademakers, R.3
Theuns, J.4
Cruts, M.5
Van Broeckhoven, C.6
-
200
-
-
0030943863
-
Dietary antioxidants and Parkinson disease
-
The Rotterdam Study
-
de Rijk, M.C.; Breteler, M.M.; den Breeijen, J.H.; Launer, L.J.; Grobbee, D.E.; van der Meche, F.G.; Hofman, A. Dietary antioxidants and Parkinson disease. The Rotterdam Study. Arch. Neurol. 1997, 54, 762-765.
-
(1997)
Arch. Neurol.
, vol.54
, pp. 762-765
-
-
De Rijk, M.C.1
Breteler, M.M.2
Den Breeijen, J.H.3
Launer, L.J.4
Grobbee, D.E.5
Van Der Meche, F.G.6
Hofman, A.7
-
201
-
-
0037178579
-
Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study
-
Morris, M.C.; Evans, D.A.; Bienias, J.L.; Tangney, C.C.; Bennett, D.A; Aggarwal, N.; Wilson, R.S.; Scherr, P.A. Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA-J. Am. Med. Assn. 2002, 287, 3230-3237.
-
(2002)
JAMA-J. Am. Med. Assn.
, vol.287
, pp. 3230-3237
-
-
Morris, M.C.1
Evans, D.A.2
Bienias, J.L.3
Tangney, C.C.4
Bennett, D.A.5
Aggarwal, N.6
Wilson, R.S.7
Scherr, P.A.8
-
202
-
-
0032147010
-
Illustration of analysis taking into account complex survey considerations: The association between wine consumption and dementia in the PAQUID study
-
Lemeshow, S.; Letenneur, L.; Dartigues, J.F.; Lafont, S.; Orgogozo, J.M.; Commenges, D. Illustration of analysis taking into account complex survey considerations: The association between wine consumption and dementia in the PAQUID study. Am. J. Epidemiol. 1998, 148, 298-306.
-
(1998)
Am. J. Epidemiol.
, vol.148
, pp. 298-306
-
-
Lemeshow, S.1
Letenneur, L.2
Dartigues, J.F.3
Lafont, S.4
Orgogozo, J.M.5
Commenges, D.6
-
203
-
-
0037090246
-
Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake
-
Checkoway, H.; Powers, K.; Smith-Weller, T.; Franklin, G.M.; Longstreth, W.T.; Swanson, P.D. Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake. Am. J. Epidemiol. 2002, 155, 732-738.
-
(2002)
Am. J. Epidemiol.
, vol.155
, pp. 732-738
-
-
Checkoway, H.1
Powers, K.2
Smith-Weller, T.3
Franklin, G.M.4
Longstreth, W.T.5
Swanson, P.D.6
-
204
-
-
0033835543
-
Intake of flavonoids and risk of dementia
-
Commenges, D.; Scotet,,V.; Renaud, S.; Jacqmin-Gadda, H.; Barberger-Gateau, P.; Dartigues, J.F. Intake of flavonoids and risk of dementia. Eur. J. Epidemiol. 2000, 16, 357-363.
-
(2000)
Eur. J. Epidemiol.
, vol.16
, pp. 357-363
-
-
Commenges, D.1
Scotet, V.2
Renaud, S.3
Jacqmin-Gadda, H.4
Barberger-Gateau, P.5
Dartigues, J.F.6
-
205
-
-
0032435412
-
Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women
-
Cao, G.; Russell, R.M.; Lischner, N.; Prior, R.L. Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women. J. Nutr. 1998, 128, 2383-2390.
-
(1998)
J. Nutr.
, vol.128
, pp. 2383-2390
-
-
Cao, G.1
Russell, R.M.2
Lischner, N.3
Prior, R.L.4
-
206
-
-
0031788259
-
The efficacy of Ginkgo biloba on cognitive function in Alzheimer disease
-
Oken, B.S.; Storzbach, D.M.; Kaye, J.A. The efficacy of Ginkgo biloba on cognitive function in Alzheimer disease. Arch. Neurol. 1998, 55, 1409-1415.
-
(1998)
Arch. Neurol.
, vol.55
, pp. 1409-1415
-
-
Oken, B.S.1
Storzbach, D.M.2
Kaye, J.A.3
-
207
-
-
0027447124
-
Inhibition of human LDL oxidation by resveratrol
-
Frankel, E.N.; Waterhouse, A.L.; Kinsella, J.E. Inhibition of human LDL oxidation by resveratrol. Lancet 1993, 341, 1103-1104.
-
(1993)
Lancet
, vol.341
, pp. 1103-1104
-
-
Frankel, E.N.1
Waterhouse, A.L.2
Kinsella, J.E.3
-
208
-
-
36148942866
-
Resveratrol induces the heat-shock response and protects human cells from severe heat stress
-
Putics, A.; Végh, E.M.; Csermely, P.; Sti, C. Resveratrol Induces the Heat-Shock Response and Protects Human Cells from Severe Heat Stress. Antioxid. Redox Signal. 2008, 10, 65-76.
-
(2008)
Antioxid. Redox Signal.
, vol.10
, pp. 65-76
-
-
Putics, A.1
Végh, E.M.2
Csermely, P.3
Sti, C.4
-
209
-
-
0034096319
-
Apolipoprotein E polymorphism and Alzheimer disease
-
The Indo-US Cross-National Dementia Study
-
Ganguli, M.; Chandra, V.; Kamboh, M.I.; Johnston, J.M.; Dodge, H.H.; Thelma, B.K; Juyal, R.C.; Pandav, R.; Belle, S.H.; DeKosky, S.T. Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study. Arch. Neurol. 2000, 57, 824-830.
-
(2000)
Arch. Neurol.
, vol.57
, pp. 824-830
-
-
Ganguli, M.1
Chandra, V.2
Kamboh, M.I.3
Johnston, J.M.4
Dodge, H.H.5
Thelma, B.K.6
Juyal, R.C.7
Pandav, R.8
Belle, S.H.9
DeKosky, S.T.10
-
210
-
-
67349266285
-
Induction of heat shock response by curcumin in human leukemia cells
-
Teiten, M.H.; Reuter, S.; Schmucker, S.; Dicato, M.; Diederich, M. Induction of heat shock response by curcumin in human leukemia cells. Cancer Lett. 2009, 279, 145-154.
-
(2009)
Cancer Lett.
, vol.279
, pp. 145-154
-
-
Teiten, M.H.1
Reuter, S.2
Schmucker, S.3
Dicato, M.4
Diederich, M.5
|