Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

Human Molecular Genetics

Volumn 13, Issue 13, 2004, Pages 1389-1405

  Hay, David G ^a,e   Sathasivam, Kirupa ^a   Tobaben, Sönke ^b   Stahl, Bernd ^c   Marber, Michael ^a   Mestril, Ruben ^d   Mahal, Amarbirpal ^a,f   Smith, Donna L ^a,g   Woodman, Ben ^a   Bates, Gillian P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Molecular Design Limited   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d LOYOLA UNIVERSITY CHICAGO   (United States)

^e NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

^g Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; DETERGENT; GELDANAMYCIN; GLUTAMINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; MESSENGER RNA; POLYGLUTAMINE; RADICICOL;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN SLICE; CAENORHABDITIS ELEGANS; CELL AGGREGATION; CELL CULTURE; CELL DEATH; CELL NUCLEUS; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; DROSOPHILA MELANOGASTER; FEMALE; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC MANIPULATION; HEAT SHOCK RESPONSE; HUNTINGTON CHOREA; INHIBITION KINETICS; MALE; MEDICAL ASSESSMENT; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; QUANTITATIVE ANALYSIS; SACCHAROMYCES CEREVISIAE; SOLUBILITY; TRANSGENICS;

ANIMALS; BENZOQUINONES; BRAIN; CELL NUCLEUS; CELLS, CULTURED; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUNTINGTON DISEASE; LACTAMS, MACROCYCLIC; LACTONES; MACROLIDES; MICE; MOLECULAR CHAPERONES; PEPTIDES; QUINONES; RNA, MESSENGER;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MELANOGASTER; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 3242695184     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddh144     Document Type: Article

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