Formation of nuclear HSF1 granules varies depending on stress stimuli

Cell Stress and Chaperones

Volumn 5, Issue 3, 2000, Pages 219-228

  Holmberg, Carina I ^a,b   Illman, Sara A ^a,b   Kallio, Marko ^a   Mikhailov, Andrey ^a   Sistonen, Lea ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; PROTEASOME INHIBITOR; RNA; SERINE;

ARTICLE; CONTROLLED STUDY; HEAT STRESS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

EID: 0033669588     PISSN: 13558145     EISSN: None     Source Type: Journal    
DOI: 10.1379/1466-1268(2000)005<0219:FONHGV>2.0.CO;2     Document Type: Article

References (44)

1. Abnormal proteins serve as eukaryotic stress signals and trigger the activation of heat shock genes
2. Heat shock-induced translational control of HSP70 and globin synthesis in chicken reticulocytes
3. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance
4. Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor 1
5. Transcriptional activity of heat shock factor 1 at 37°C is repressed through phosphorylation on two distinct serine residues by glycogen synthase kinase 3α and protein kinases Cα and Cζ
6. HSF1 granules: A novel stress-induced nuclear compartment of human cells
7. Activation of heat shock factor 1 DNA binding precedes stress-induced serine phosphorylation
8. Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family
9. Phosphorylation of Drosophila heat shock transcription factor
10. Isolation and characterization of full-length cDNA clones from human α-, β-, and γ-actin mRNAs: Skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed
11. Glycogen synthase kinase 3β and extracellular signal-regulated kinase inactivate heat shock transcription factor 1 by facilitating the disappearance of transcriptionally active granules after heat shock
12. The phorbol ester 12-Otetradecanoylphorbol 13-acetate enhances the heat-induced stress response
13. Conventional and novel PKC isoenzymes modify the heat induced stress response but are not activated by heat shock
14. HSF1 transcription factor concentrates in nuclear foci during heat shock: Relationship with transcription sites
15. Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules
16. Salicylate triggers heat shock factor differently than heat
17. Arachidonate is a potent modulator of human heat shock gene transcription
18. Proteasome inhibition leads to the activation of all members of the heat-shockfactor family
19. Proteasome inhibitors MG132 and lactacystin hyperphosphorylate HSF1 and induce hsp70 and hsp27 expression
20. Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation
21. Repression of human heat shock factor I activity at control temperature by phosphorylation
22. Activation in vitro of sequence-specific DNA binding by a human regulatory factor
23. Pharmacological modulation of heat shock factor I by anti-inflammatory drugs results in protection against stress-induced cellular damage
24. Proteasome inhibitors: Valuable new tools for cell biologists
25. Proteasome inhibitors cause induction of heat shock proteins and trehalose, which together confer thermotolerance in Saccharomyces cerevisiae
26. Oxidative stress induces heat shock factor phosphorylation and HSF-dependent activation of yeast metallothionein gene transcription
27. Heat shock response and protein degradation: Regulation of HSF2 by the ubiquitin-proteasome pathway
28. Displacement of sequence-specific transcription factors from mitotic chromatin
29. Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress
30. Proteasome inhibitors activate stress kinases and induce Hsp72: Diverse effects on apoptosis
31. Inhibitors of tyrosine and Ser/Thr phosphatases modulate the heat shock response
32. Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
33. Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells
34. Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway
35. Activation of heat shock gene transcription by HSF1 involves oligomerization, acquisition of DNA binding activity, and nuclear localization and can occur in the absence of stress
36. Expression and purification of human heat shock factor 1
37. Yeast heat shock factor contains separable transient and sustained response transcriptional activators
38. Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation
39. Phosphopeptide mapping and phosphoamino acid analysis on cellulose thin-layer plates
40. A novel hnRNP protein (HAP/SAF-B) enters a subset of hnRNP complexes and relocates in nuclear granules in response to heat shock
41. Maximal stress-induced transcription from the human Hsp70 promoter requires interactions with the basal promoter elements independent of rotational alignment
42. The heat shock factors: Structure and regulation
43. Structure and expression of the human gene encoding major heat shock protein HSP70
44. Evidence that a rapidly turning over protein, normally degraded by the proteasomes, regulates hsp72 gene transcription in HepG2 cells