P-TEFb kinase recruitment and function at heat shock loci

Genes and Development

Volumn 14, Issue 7, 2000, Pages 792-803

  Lis, John T ^a   Mason, Paul ^a   Peng, J ^b   Price, David H ^b   Werner, Janis ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Cdk9; Cyclin T; Elongation; HSF; Polytene chromosomes; Transcription regulation

Indexed keywords

HEAT SHOCK PROTEIN;

ARTICLE; DROSOPHILA; ENZYME LOCALIZATION; GENE LOCUS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; RNA TRANSLATION; TRANSCRIPTION REGULATION;

ANIMALS; CELL LINE; CHROMOSOME MAPPING; CYCLIN-DEPENDENT KINASE 9; CYCLIN-DEPENDENT KINASES; CYCLINS; DIMERIZATION; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HEAT; HSP70 HEAT-SHOCK PROTEINS; PHOSPHORYLATION; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SALIVARY GLANDS; TRANSCRIPTION, GENETIC; TRANSFECTION;

HEXAPODA;

EID: 0034175631     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Artavanis-Tsakonas, S., P. Schedl, M.-E. Mirault, L. Moran, and J. Lis. 1979. Genes for the 70,000 dalton heat shock protein in two cloned D. melanogaster DNA segments. Cell 17: 9-18.
2. Ashburner, M. 1972. Puffing patterns in Drosophila melanogaster and related species. In Developmental studies on giant chromosomes, (ed. W. Beermann). pp. 101-151. Springer-Verlag, New York, NY.
3. Bieniasz, P.D., T.A. Grdina, H.P. Bogerd, and B.R. Cullen. 1999. Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription. Proc. Natl. Acad. Sci. 96: 7791-7796.
4. Brown, S.A., A.N. Imbalzano, and R.E. Kingston. 1996. Activator-dependent regulation of transcriptional pausing on nucleosomal templates. Genes & Dev. 10: 1479-1490.
5. Clos, J., S. Rabindran, J. Wisnewski, and C. Wu. 1993. Induction temperature of human heat shock factor is reprogrammed in a Drosophila cell environment. Nature 364: 252-255.
6. Crowley, T.E., M.W. Bond, and E.M. Meyerowitz. 1983. The structural genes for three Drosophila glue proteins reside at a single polytene chromosome puff locus. Mol. Cell. Biol. 3: 623-634.
7. Dahmus, M.E. 1994. The role of multisite phosphorylation in the regulation of RNA polymerase II activity. Prog. Nucleic Acid Res. Mol. Biol. 48: 143-179.
8. Dequin, R., H. Saumweber, and J.W. Sedat. 1984. Proteins shifting from the cytoplasm into the nuclei during early embryogenesis of Drosophila melanogaster. Dev. Biol. 104: 37-48.
9. Dvir, A., R.C. Conaway, and J.W. Conaway. 1997. A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes. Proc. Natl. Acad. Sci. 94: 9006-9010.
10. Edwards, M.C., C. Wong, and S.J. Elledge. 1998. Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity. Mol. Cell. Biol. 7: 4291-4300.
11. Garber, M.E., P. Wei, V.N. KewalRamani, T.P. Mayall, C.H. Herrmann, A.P. Rice, D.R. Littman, and K.A. Jones. 1998. The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes & Dev. 12: 3512-3527.
12. Giardina, C. and J.T. Lis. 1995. Sodium salicylate and yeast heat shock gene transcription. J. Biol. Chem. 270: 10369-10372.
13. Giardina, C., M. Perez Riba, and J.T. Lis. 1992. Promoter melting and TFIID complexes on Drosophila genes in-vivo. Genes & Dev. 6: 2190-2200.
14. Goodrich, J.A. and R. Tjian. 1994. Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II. Cell 77: 145-156.
15. Greenleaf, A.L., U. Plagens, M. Jamrich, and E.K.F. Bautz. 1978. RNA polymerase B (or II) in heat induced puffs of Drosophila polytene chromosomes. Chromosoma 65: 127-136.
16. Guay, P.S. and G.M. Guild. 1991. The ecdysone-induced puffing cascade in Drosophila salivary glands: A Broad-Complex early gene regulates intermolt and late gene transcription. Genetics 129: 169-175.
17. Guild, G.M. and E.M. Shore. 1984. Larval salivary gland secretion proteins in Drosophila. Identification and characterization of the Sgs-5 structural gene. J. Mol. Biol. 179: 289-314.
18. Hartzog, G.A., T. Wada, H. Handa, and F. Winston. 1998. Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes & Dev. 12: 357-369.
19. Ish-Horowicz, D. and S.M. Pinchin. 1980. Genomic organization of the 87A7 and 87C1 heat-induced loci of Drosophila melanogaster. J. Mol. Biol. 142: 231-245.
20. Jedlicka, P., M. Mortin, and C. Wu. 1997. Multiple functions of Drosophila heat shock transcription factor in vivo. EMBO J. 16: 2452-2462.
21. Kanazawa, S., T. Okamoto, and B.M. Peterlin. 2000. Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection. Immunity 12: 61-70.
22. Kim, Y.-J., S. Bjorklund, Y. Li, M.H. Sayre, and R.D. Kornberg. 1994. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77: 599-608.
23. Kraus, K.W., Y. Lee, J.T. Lis, and M.F. Wolfner. 1988. Sex-specific control of Drosophila-melanogaster yolk protein 1 gene expression is limited to transcription. Mol. Cell. Biol. 8: 4756-4764.
24. Kraus, W.L., E.T. Manning, and J.T. Kadonaga. 1999. Biochemical analysis of distinct activation functions in p300 that enhance transcription initiation with chromatin templates. Mol. Cell. Biol. 19: 8123-8135.
25. Krumm, A., T. Meulia, M. Brunvand, and M. Groudine. 1992. The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region. Genes & Dev. 6: 2201-2213.
26. Laspia, M.F., P. Wendel, and M.B. Mathews. 1993. HIV-1 Tat overcomes inefficient transcriptional elongation in vitro. J. Mol. Biol. 232: 732-746.
27. Law, A., K. Hirayoshi, T. O'Brien, and J.T. Lis. 1998. Direct cloning of DNA that interacts in vivo with a specific protein: Application to RNA polymerase II and sites of pausing in Drosophila. Nucleic Acids Res. 26: 919-924.
28. Lis, J. 1998. Promoter-associated pausing in promoter architecture and postinitiation transcriptional regulation. Cold Spring Harb. Symp. Quant. Biol. 63: 347-356.
29. Lis, J.T., D. Ish-Horowicz, and S.M. Pinchin. 1981a. Genomic organization and transcription of the αβ heat shock DNA in Drosophila melanogaster. Nucleic Acids Res. 9: 5297-5310.
30. Lis, J.T., W. Neckameyer, R. Dubensky, and N. Costlow. 1981b. Cloning and characterization of nine heat-shock-induced mRNAs of Drosophila melanogaster. Gene 15: 67-80.
31. Lu, H., O. Flores, R. Weinmann, and D. Reinberg. 1991. The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex. Proc. Natl. Acad. Sci. 88: 10004-10008.
32. Mancebo, H.S.Y., G. Lee, J. Flygare, J. Tomassini, P. Luu, Y. Zhu, J. Peng, C. Blau, D. Hazuda, D. Price, and O. Flores. 1997. P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes & Dev. 11: 2633-2644.
33. Marshall, N.F. and D.H. Price. 1995. Purification of P-TEFb, a transcription factor required for the transition into productive elongation. J. Biol. Chem. 270: 12335-12338.
34. Marshall, N.F., J. Peng, Z. Xie, and D.H. Price. 1996. Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase. J. Biol. Chem. 271: 27176-27183.
35. Mirault, M.-E., M. Goldschmidt-Clermont, S. Artavanis-Tsakonas, and P. Schedl. 1979. Organization of the multiple genes for the 70,000-dalton heat-shock protein in Drosophila melanogaster. Proc. Natl. Acad. Sci. 76: 5254-5258.
36. O'Brien, T. and J.T. Lis. 1993. Rapid changes in Drosophila transcription after an instantaneous heat shock. Mol. Cell. Biol. 13: 3456-3463.
37. O'Brien, T., S. Hardin, A. Greenleaf, and J.T. Lis. 1994. Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. Nature 370: 75-77.
38. Peng, J., N.F. Marshall, and D.H. Price. 1998a. Identification of a cyclin subunit required for the function of Drosophila P-TEFb. J. Biol. Chem. 273: 13855-13860.
39. Peng, J., Y. Zhu, J.T. Milton, and D.H. Price. 1998b. Identification of multiple cyclin subunits of human P-TEFb. Genes & Dev. 12: 755-762.
40. Plet, A., D. Eick, and J.M. Blanchard. 1995. Elongation and premature termination of transcripts initiated from c-fos and c-myc promoters show dissimilar patterns. Oncogene 10: 319-328.
41. Price, D.H. 2000. P-TEFb, a cyclin dependent kinase controlling elongation by RNA polymerase II. Mol. Cell. Biol. (in press).
42. Price, D.H., A.E. Sluder, and A.L. Greenleaf. 1987. Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts. J. Biol. Chem. 262: 3244-3255.
43. Rasmussen, E.B. and J.T. Lis. 1993. In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes. Proc. Natl Acad. Sci. 90: 7923-7927.
44. Rougvie, A.E. and J.T. Lis. 1990. Postinitiation transcriptional control in Drosophila melanogaster. Mol. Cell. Biol. 10: 6041-6045.
45. Rubin, G.M. and A.C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218: 348-353.
46. Shopland, L.S. and J.T. Lis. 1996. HSF recruitment and loss at most Drosophila heat shock loci is coordinated and depends on proximal promoter sequences. Chromosoma 105: 158-171.
47. Shopland, L.S., K. Hirayoshi, M. Fernandes, and J.T. Lis. 1995. HSF access to heat shock elements in vivo depends critically on promoter architecture defined by GAGA factor, TFIID, and RNA polymerase II binding sites. Genes & Dev. 9: 2756-2769.
48. Simon, J. and J. Lis. 1987. A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements. Nucleic Acids Res. 15: 2971-2988.
49. Strobl, L.J. and D. Eick. 1992. Hold back of RNA polymerase II at the transcription start site mediates down-regulation of c-myc in vivo. EMBO J. 11: 3307-3314.
50. Svejstrup, J.Q., P. Vichi, and J.M. Egly. 1996. The multiple roles of transcription/repair factor TFIIH. Trends Biochem. Sci. 21: 346-350.
51. Tirode, F., D. Busso, F. Coin, and J.M. Egly. 1999. Reconstitution of the transcription factor TFIIH: Assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7. Mol. Cell 3: 87-95.
52. Wada, T., T. Takagi, Y. Yamaguchi, A. Ferdous, T. Imai, S. Hirose, S. Sugimoto, K. Yano, G.A. Hartzog, F. Winston et al. 1998. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes & Dev. 12: 343-356.
53. Weeks, J.R., S.E. Hardin, J. Shen, J.M. Lee, and A.L. Greenleaf. 1993. Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: Correlations with gene activity and transcript processing. Genes & Dev. 7: 2329-2344.
54. Westwood, J.T., J. Clos, and C. Wu. 1991. Stress-induced oligomerization and chromosomal relocalization of heat-shock factor. Nature 353: 822-827.
55. Wilkins, R.C. and J.T. Lis. 1997. Dynamics of potentiation and activation: GAGA factor and its role in heat shock gene regulation. Nucleic Acids Res. 25: 3963-3968.
56. Wisniewski, J., A. Orosz, R. Allada, and C. Wu. 1996. The C-terminal region of Drosophila heat shock factor (HSF) contains a constitutively functional transactivation domain. Nucleic Acids Res. 24: 367-374.
57. Xiao, H. and J.T. Lis. 1988. Germline transformation used to define key features of heat-shock response elements. Science 239: 1139-1142.
58. Yamaguchi, Y., T. Takagi, T. Wada, K. Yano, A. Furuya, S. Sugimoto, J. Hasegawa, and H. Handa. 1999a. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 97: 41-51.
59. Yamaguchi, Y., T. Wada, D. Watanabe, T. Takagi, J. Hasegawa, and H. Handa. 1999b. Structure and function of the human transcription elongation factor DSIF. J. Biol. Chem. 274: 8085-8092.
60. Zhu, Y., T. Pe'ery, J. Peng, Y. Ramanathan, N. Marshall, T. Marshall, B. Amendt, M.B. Mathews, and D.H. Price. 1997. Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro. Genes & Dev. 11: 2622-2632.