Heat shock protein 70 inhibits α-synuclein fibril formation via preferential binding to prefibrillar species

Journal of Biological Chemistry

Volumn 280, Issue 15, 2005, Pages 14733-14740

  Dedmon, Matthew M ^a   Christodoulou, John ^a   Wilson, Mark R ^b   Dobson, Christopher M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DISEASES; HISTOLOGY; INCLUSIONS; NEUROLOGY; PATHOLOGY; TOXICITY;

CELLULAR TOXICITY; HEAT STOCK PROTEINS; INTRACELLULER PROTEINACEOUS INCLUSIONS; LEWY BODIES;

PROTEINS;

ALPHA SYNUCLEIN; CHAPERONE; HEAT SHOCK PROTEIN 70;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FIBER; HUMAN; HUMAN CELL; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN FUNCTION;

ALPHA-SYNUCLEIN; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; FLOW CYTOMETRY; GENETIC VECTORS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LEWY BODIES; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MOLECULAR CHAPERONES; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SUBCELLULAR FRACTIONS; SYNUCLEINS; THIAZOLES; TIME FACTORS;

EID: 17644383748     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413024200     Document Type: Article

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