-
1
-
-
1042268168
-
G-quartets 40 years later: From 5'-GMP to molecular biology and supramolecular chemistry
-
Davis, J.T. G-quartets 40 years later: From 5'-GMP to molecular biology and supramolecular chemistry. Angew. Chem. Int. Ed., 2004, 43, 668-698.
-
(2004)
Angew. Chem. Int. Ed
, vol.43
, pp. 668-698
-
-
Davis, J.T.1
-
2
-
-
66549124907
-
The structures of quadruplex nucleic acids and their drug complexes
-
Neidle, S. The structures of quadruplex nucleic acids and their drug complexes. Curr. Opin. Struct. Biol., 2009, 19, 239-250.
-
(2009)
Curr. Opin. Struct. Biol
, vol.19
, pp. 239-250
-
-
Neidle, S.1
-
3
-
-
20144369806
-
Highly prevalent putative quadruplex sequence motifs in human DNA
-
Todd, A.K.; Johnston, M.; Neidle, S. Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res., 2005, 33, 2901-2907.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2901-2907
-
-
Todd, A.K.1
Johnston, M.2
Neidle, S.3
-
4
-
-
20144364292
-
Prevalence of quadruplexes in the human genome
-
Huppert, J.L.; Balasubramanian, S. Prevalence of quadruplexes in the human genome. Nucleic Acids Res., 2005, 33, 2908-2916.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2908-2916
-
-
Huppert, J.L.1
Balasubramanian, S.2
-
5
-
-
33748052721
-
Quadruplex-based molecular beacons as tunable DNA probes
-
Bourdoncle, A.; Torres, A.E.; Gosse, C.; Lacroix, L.; Vekhoff, P.; Le Saux, T.; Jullien, L.; Mergny, J.L. Quadruplex-based molecular beacons as tunable DNA probes. J. Am. Chem. Soc., 2006, 128, 11094-11105.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 11094-11105
-
-
Bourdoncle, A.1
Torres, A.E.2
Gosse, C.3
Lacroix, L.4
Vekhoff, P.5
Le Saux, T.6
Jullien, L.7
Mergny, J.L.8
-
6
-
-
34250845845
-
Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene C- kit
-
Shirude, P.S.; Okumus, B.; Ying, L.M.; Ha, T.; Balasubramanian, S. Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene C- kit. J. Am. Chem. Soc., 2007, 129, 7484-7485.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 7484-7485
-
-
Shirude, P.S.1
Okumus, B.2
Ying, L.M.3
Ha, T.4
Balasubramanian, S.5
-
7
-
-
33846928449
-
G-quadruplexes in promoters throughout the human genome
-
Huppert, J.L.; Balasubramanian, S. G-quadruplexes in promoters throughout the human genome. Nucleic Acids Res., 2007, 35, 406-413.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 406-413
-
-
Huppert, J.L.1
Balasubramanian, S.2
-
8
-
-
38049030699
-
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: Diverse higher order DNA and RNA targets for cancer therapeutics
-
Patel, D.J.; Phan, A.T.; Kuryavyi, V. Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: Diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res., 2007, 35, 7429-7455.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7429-7455
-
-
Patel, D.J.1
Phan, A.T.2
Kuryavyi, V.3
-
9
-
-
47849105417
-
Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions
-
Qin, Y.; Hurley, L.H. Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions. Biochimie, 2008, 90, 1149-1171.
-
(2008)
Biochimie
, vol.90
, pp. 1149-1171
-
-
Qin, Y.1
Hurley, L.H.2
-
10
-
-
37049004147
-
Targeting telomeres and telomerase
-
De Cian, A.; Lacroix, L.; Douarre, C.; Temime-Smaali, N.; Trentesaux, C.; Riou, J.F.; Mergny, J.L. Targeting telomeres and telomerase. Biochimie, 2008, 90, 131-155.
-
(2008)
Biochimie
, vol.90
, pp. 131-155
-
-
de Cian, A.1
Lacroix, L.2
Douarre, C.3
Temime-Smaali, N.4
Trentesaux, C.5
Riou, J.F.6
Mergny, J.L.7
-
12
-
-
0037142071
-
Crystal structure of parallel quadruplexes from human telomeric DNA
-
Parkinson, G.N.; Lee, M.P.H.; Neidle, S. Crystal structure of parallel quadruplexes from human telomeric DNA. Nature, 2002, 417, 876-880.
-
(2002)
Nature
, vol.417
, pp. 876-880
-
-
Parkinson, G.N.1
Lee, M.P.H.2
Neidle, S.3
-
13
-
-
0027918585
-
Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex
-
Wang, Y.; Patel, D.J. Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex. Structure, 1993, 1, 263-282.
-
(1993)
Structure
, vol.1
, pp. 263-282
-
-
Wang, Y.1
Patel, D.J.2
-
14
-
-
33746600695
-
Structure of the human telomere in K+ solution: An intramolecular (3+1) G-quadruplex scaffold
-
Luu, K.N.; Phan, A.T.; Kuryavyi, V.; Lacroix, L.; Patel, D.J. Structure of the human telomere in K+ solution: An intramolecular (3+1) G-quadruplex scaffold. J. Am. Chem. Soc., 2006, 128, 9963-9970.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 9963-9970
-
-
Luu, K.N.1
Phan, A.T.2
Kuryavyi, V.3
Lacroix, L.4
Patel, D.J.5
-
15
-
-
33750970018
-
Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution
-
Phan, A.T.; Luu, K.N.; Patel, D.J. Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution. Nucleic Acids Res., 2006, 34, 5715-5719.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 5715-5719
-
-
Phan, A.T.1
Luu, K.N.2
Patel, D.J.3
-
16
-
-
67749124298
-
Structure of the Human Telomere in K+ Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers
-
Lim, K.W.; Amrane, S.; Bouaziz, S.; Xu, W.X.; Mu, Y.G.; Patel, D.J.; Luu, K.N.; Phan, A.T. Structure of the Human Telomere in K+ Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers. J. Am. Chem. Soc., 2009, 131, 4301-4309.
-
(2009)
J. Am. Chem. Soc
, vol.131
, pp. 4301-4309
-
-
Lim, K.W.1
Amrane, S.2
Bouaziz, S.3
Xu, W.X.4
Mu, Y.G.5
Patel, D.J.6
Luu, K.N.7
Phan, A.T.8
-
17
-
-
0036290781
-
Crystal structure of the potassium form of an Oxytricha nova G-quadruplex
-
Haider, S.; Parkinson, G.N.; Neidle, S. Crystal structure of the potassium form of an Oxytricha nova G-quadruplex. J. Mol. Biol., 2002, 320, 189-200.
-
(2002)
J. Mol. Biol
, vol.320
, pp. 189-200
-
-
Haider, S.1
Parkinson, G.N.2
Neidle, S.3
-
18
-
-
0037423728
-
Structure of a G- quadruplex-ligand complex
-
Haider, S.M.; Parkinson, G.N.; Neidle, S. Structure of a G- quadruplex-ligand complex. J. Mol. Biol., 2003, 326, 117-125.
-
(2003)
J. Mol. Biol
, vol.326
, pp. 117-125
-
-
Haider, S.M.1
Parkinson, G.N.2
Neidle, S.3
-
19
-
-
0242684479
-
Selective recognition of G-quadruplex telomeric DNA by a bis(quinacridine) macrocycle
-
Teulade-Fichou, M.P.; Carrasco, C.; Guittat, L.; Bailly, C.; Alberti, P.; Mergny, J.L.; David, A.; Lehn, J.M.; Wilson, W.D. Selective recognition of G-quadruplex telomeric DNA by a bis(quinacridine) macrocycle. J. Am. Chem. Soc., 2003, 125, 4732-4740.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 4732-4740
-
-
Teulade-Fichou, M.P.1
Carrasco, C.2
Guittat, L.3
Bailly, C.4
Alberti, P.5
Mergny, J.L.6
David, A.7
Lehn, J.M.8
Wilson, W.D.9
-
20
-
-
33644890205
-
Neomycin-capped aromatic platforms: Quadruplex DNA recognition and telomerase inhibition
-
Kaiser, M.; De Cian, A.; Sainlos, M.; Renner, C.; Mergny, J.L.; Telaude-Fichou, M.P. Neomycin-capped aromatic platforms: quadruplex DNA recognition and telomerase inhibition. Org. Biomol. Chem., 2006, 4, 1049-1057.
-
(2006)
Org. Biomol. Chem
, vol.4
, pp. 1049-1057
-
-
Kaiser, M.1
de Cian, A.2
Sainlos, M.3
Renner, C.4
Mergny, J.L.5
Telaude-Fichou, M.P.6
-
21
-
-
47649124369
-
G-quadruplexes: Targets in anticancer drug design
-
Ou, T.M.; Lu, Y.J.; Tan, J.H.; Huang, Z.S.; Wong, K.Y.; Gu, L.Q. G-quadruplexes: Targets in anticancer drug design. ChemMedChem, 2008, 3, 690-713.
-
(2008)
ChemMedChem
, vol.3
, pp. 690-713
-
-
Ou, T.M.1
Lu, Y.J.2
Tan, J.H.3
Huang, Z.S.4
Wong, K.Y.5
Gu, L.Q.6
-
22
-
-
39049147645
-
A hitchhiker's guide to G- quadruplex ligands
-
Monchaud, D.; Teulade-Fichou, M.P. A hitchhiker's guide to G- quadruplex ligands. Org. Biomol. Chem., 2008, 6, 627-636.
-
(2008)
Org. Biomol. Chem
, vol.6
, pp. 627-636
-
-
Monchaud, D.1
Teulade-Fichou, M.P.2
-
23
-
-
66149087629
-
G-Quadruplex DNA Structures and Organic Chemistry: More Than One Connection
-
Franceschin, M. G-Quadruplex DNA Structures and Organic Chemistry: More Than One Connection. Eur. J. Org. Chem., 2009, 2225-2238.
-
(2009)
Eur. J. Org. Chem
, pp. 2225-2238
-
-
Franceschin, M.1
-
24
-
-
55249100310
-
Design of Selective G-quadruplex ligands as potential anticancer agents
-
Tan, J.H.; Gu, L.Q.; Wu, J.Y. Design of Selective G-quadruplex ligands as potential anticancer agents. Mini-Rev. Med. Chem., 2008, 8, 1163-1178.
-
(2008)
Mini-Rev. Med. Chem
, vol.8
, pp. 1163-1178
-
-
Tan, J.H.1
Gu, L.Q.2
Wu, J.Y.3
-
25
-
-
64249133326
-
Targeting G-Quadruplex DNA with Small Molecules
-
Luedtke, N.W. Targeting G-Quadruplex DNA with Small Molecules. Chimia, 2009, 63, 134-139.
-
(2009)
Chimia
, vol.63
, pp. 134-139
-
-
Luedtke, N.W.1
-
26
-
-
0035857396
-
Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus
-
Shin-ya, K.; Wierzba, K.; Matsuo, K.; Ohtani, T.; Yamada, Y.; Furihata, K.; Hayakawa, Y.; Seto, H. Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus. J. Am. Chem. Soc., 2001, 123, 1262-1263.
-
(2001)
J. Am. Chem. Soc
, vol.123
, pp. 1262-1263
-
-
Shin-Ya, K.1
Wierzba, K.2
Matsuo, K.3
Ohtani, T.4
Yamada, Y.5
Furihata, K.6
Hayakawa, Y.7
Seto, H.8
-
27
-
-
36849081775
-
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action
-
De Cian, A.; Cristofari, G.; Reichenbach, P.; De Lemos, E.; Monchaud, D.; Teulade-Fichou, M.P.; Shin-Ya, K.; Lacroix, L.; Lingner, J.; Mergny, J.L. Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proc. Natl. Acad. Sci. U.S.A., 2007, 104, 17347-17352.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 17347-17352
-
-
de Cian, A.1
Cristofari, G.2
Reichenbach, P.3
de Lemos, E.4
Monchaud, D.5
Teulade-Fichou, M.P.6
Shin-Ya, K.7
Lacroix, L.8
Lingner, J.9
Mergny, J.L.10
-
28
-
-
46649106069
-
TRAP-LIG a modified telomere repeat amplification protocol assay to quantitate telomerase inhibition by small molecules
-
Reed, J.; Gunaratnam, M.; Beltran, M.; Reszka, A.P.; Vilar, R.; Neidle, S. TRAP-LIG, a modified telomere repeat amplification protocol assay to quantitate telomerase inhibition by small molecules. Analyt. Biochem., 2008, 380, 99-105.
-
(2008)
Analyt. Biochem
, vol.380
, pp. 99-105
-
-
Reed, J.1
Gunaratnam, M.2
Beltran, M.3
Reszka, A.P.4
Vilar, R.5
Neidle, S.6
-
29
-
-
0037070575
-
Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular G- quadruplex
-
Kim, M.Y.; Vankayalapati, H.; Kazuo, S.; Wierzba, K.; Hurley, L.H. Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular G- quadruplex. J. Am. Chem. Soc., 2002, 124, 2098-2099.
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 2098-2099
-
-
Kim, M.Y.1
Vankayalapati, H.2
Kazuo, S.3
Wierzba, K.4
Hurley, L.H.5
-
30
-
-
21644460419
-
Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure
-
Rezler, E.M.; Seenisamy, J.; Bashyam, S.; Kim, M.Y.; White, E.; Wilson, W.D.; Hurley, L.H. Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure. J. Am. Chem. Soc., 2005, 127, 9439-9447.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 9439-9447
-
-
Rezler, E.M.1
Seenisamy, J.2
Bashyam, S.3
Kim, M.Y.4
White, E.5
Wilson, W.D.6
Hurley, L.H.7
-
31
-
-
33748701981
-
Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: In vitro and in vivo studies in acute leukemia
-
Tauchi, T.; Shin-ya, K.; Sashida, G.; Sumi, M.; Okabe, S.; Ohyashiki, J.H.; Ohyashiki, K. Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia. Oncogene, 2006, 25, 5719-5725.
-
(2006)
Oncogene
, vol.25
, pp. 5719-5725
-
-
Tauchi, T.1
Shin-Ya, K.2
Sashida, G.3
Sumi, M.4
Okabe, S.5
Ohyashiki, J.H.6
Ohyashiki, K.7
-
32
-
-
32144456223
-
The telomerase inhibitor telomestatin induces telomere shortening and cell death in Arabidopsis
-
Zhang, L.L.; Tamura, K.; Shin-ya, K.; Takahashi, H. The telomerase inhibitor telomestatin induces telomere shortening and cell death in Arabidopsis. Biochim. Biophys. Acta: Mol. Cell Res., 2006, 1763, 39-44.
-
(2006)
Biochim. Biophys. Acta: Mol. Cell Res
, vol.1763
, pp. 39-44
-
-
Zhang, L.L.1
Tamura, K.2
Shin-Ya, K.3
Takahashi, H.4
-
33
-
-
33845994055
-
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells
-
Gomez, D.; Wenner, T.; Brassart, B.; Douarre, C.; O'Donohue, M.F.; El Khoury, V.; Shin-Ya, K.; Morjani, H.; Trentesaux, C.; Riou, J.F. Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells. J. Biol. Chem., 2006, 281, 38721-38729.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 38721-38729
-
-
Gomez, D.1
Wenner, T.2
Brassart, B.3
Douarre, C.4
O'Donohue, M.F.5
El Khoury, V.6
Shin-Ya, K.7
Morjani, H.8
Trentesaux, C.9
Riou, J.F.10
-
34
-
-
28244437839
-
Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells
-
Binz, N.; Shalaby, T.; Rivera, P.; Shin-Ya, K.; Grotzer, M.A. Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells. Eur. J. Cancer, 2005, 41, 2873-2881.
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 2873-2881
-
-
Binz, N.1
Shalaby, T.2
Rivera, P.3
Shin-Ya, K.4
Grotzer, M.A.5
-
35
-
-
4744357958
-
Interaction of telomestatin with the telomeric single-strand overhang
-
Gomez, D.; Paterski, R.; Lemarteleur, T.; Shin-ya, K.; Mergny, J.L.; Riou, J.F. Interaction of telomestatin with the telomeric single-strand overhang. J. Biol. Chem., 2004, 279, 41487-41494.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 41487-41494
-
-
Gomez, D.1
Paterski, R.2
Lemarteleur, T.3
Shin-Ya, K.4
Mergny, J.L.5
Riou, J.F.6
-
36
-
-
0037731436
-
The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures
-
Kim, M.Y.; Gleason-Guzman, M.; Izbicka, E.; Nishioka, D.; Hurley, L.H. The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures. Cancer Res., 2003, 63, 3247-3256.
-
(2003)
Cancer Res
, vol.63
, pp. 3247-3256
-
-
Kim, M.Y.1
Gleason-Guzman, M.2
Izbicka, E.3
Nishioka, D.4
Hurley, L.H.5
-
37
-
-
0041353443
-
Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT- 095), against human leukemia cells: Involvement of ATM- dependent DNA damage response pathways
-
Tauchi, T.; Shin-ya, K.; Sashida, G.; Sumi, M.; Nakajima, A.; Shimamoto, T.; Ohyashiki, J.H.; Ohyashiki, K. Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT- 095), against human leukemia cells: involvement of ATM- dependent DNA damage response pathways. Oncogene, 2003, 22, 5338-5347.
-
(2003)
Oncogene
, vol.22
, pp. 5338-5347
-
-
Tauchi, T.1
Shin-Ya, K.2
Sashida, G.3
Sumi, M.4
Nakajima, A.5
Shimamoto, T.6
Ohyashiki, J.H.7
Ohyashiki, K.8
-
38
-
-
70349084987
-
The G-quadruplex ligand telomestatin impairs binding of topoisomerase III alpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells
-
Temime-Smaali, N.; Guittat, L.; Sidibe, A.; Shin-Ya, K.; Trentesaux, C.; Riou, J.F. The G-quadruplex ligand telomestatin impairs binding of topoisomerase III alpha to G-quadruplexforming oligonucleotides and uncaps telomeres in ALT cells. Plos One, 2009, 4.
-
(2009)
Plos One
, pp. 4
-
-
Temime-Smaali, N.1
Guittat, L.2
Sidibe, A.3
Shin-Ya, K.4
Trentesaux, C.5
Riou, J.F.6
-
39
-
-
59649090705
-
Studying telomere replication by Q-CO-FISH: The effect of telomestatin, a potent G- quadruplex ligand
-
Arnoult, N.; Shin-Ya, K.; Londono-Vallejo, J.A. Studying telomere replication by Q-CO-FISH: the effect of telomestatin, a potent G- quadruplex ligand. Cytogenet. Genome Res., 2008, 122, 229-236.
-
(2008)
Cytogenet. Genome Res
, vol.122
, pp. 229-236
-
-
Arnoult, N.1
Shin-Ya, K.2
Londono-Vallejo, J.A.3
-
41
-
-
77957931396
-
-
WO 2004078764
-
Shin-ya, K.; Tauchi, T.; Hoshi, T.; Ono, T.; Hiraki, Y. WO 2004078764, 2004.
-
(2004)
-
-
Shin-Ya, K.1
Tauchi, T.2
Hoshi, T.3
Ono, T.4
Hiraki, Y.5
-
42
-
-
33750177934
-
Synthesis of the penta-oxazole core of telomestatin in a convergent approach to poly-oxazole macrocycles
-
Marson, C.M.; Saadi, M. Synthesis of the penta-oxazole core of telomestatin in a convergent approach to poly-oxazole macrocycles. Org. Biomol. Chem., 2006, 4, 3892-3893.
-
(2006)
Org.Biomol.Chem
, vol.4
, pp. 3892-3893
-
-
Marson, C.M.1
Saadi, M.2
-
43
-
-
33646258754
-
Efficient construction of a doubly functionalized trisoxazole derivative relevant to the synthesis of the novel telomerase inhibitor telomestatin and its analogues
-
Chattopadhyay, S.K.; Biswas, S.; Pal, B.K. Efficient construction of a doubly functionalized trisoxazole derivative relevant to the synthesis of the novel telomerase inhibitor telomestatin and its analogues. Synthesis, 2006, 1289-1294.
-
(2006)
Synthesis
, pp. 1289-1294
-
-
Chattopadhyay, S.K.1
Biswas, S.2
Pal, B.K.3
-
44
-
-
33749261245
-
Convergent synthesis of a 24- membered macrocyclic hexaoxazole derivative related to the novel telomerase inhibitor telomestatin
-
Chattopadhyay, S.K.; Biswas, S. Convergent synthesis of a 24- membered macrocyclic hexaoxazole derivative related to the novel telomerase inhibitor telomestatin. Tetrahedron Lett., 2006, 47, 7897-7900.
-
(2006)
Tetrahedron Lett
, vol.47
, pp. 7897-7900
-
-
Chattopadhyay, S.K.1
Biswas, S.2
-
45
-
-
43749097876
-
Novel polyoxazole-based cyclopeptides from Streptomyces sp. Total synthesis of the cyclopeptide YM-216391 and synthetic studies towards telomestatin
-
Deeley, J.; Bertram, A.; Pattenden, G. Novel polyoxazole-based cyclopeptides from Streptomyces sp. Total synthesis of the cyclopeptide YM-216391 and synthetic studies towards telomestatin. Org. Biomol. Chem., 2008, 6, 1994-2010.
-
(2008)
Org. Biomol. Chem
, vol.6
, pp. 1994-2010
-
-
Deeley, J.1
Bertram, A.2
Pattenden, G.3
-
46
-
-
0037588850
-
Useful synthesis of the longer array oxazole rings for telomestatin
-
Endoh, N.; Tsuboi, K.; Kim, R.; Yonezawa, Y.; Shin, C. Useful synthesis of the longer array oxazole rings for telomestatin. Heterocycles, 2003, 60, 1567-1572.
-
(2003)
Heterocycles
, vol.60
, pp. 1567-1572
-
-
Endoh, N.1
Tsuboi, K.2
Kim, R.3
Yonezawa, Y.4
Shin, C.5
-
47
-
-
34247199404
-
Iterative two-step strategy for C2- C4 ' linked poly-oxazole synthesis using Suzuki-Miyaura cross-coupling reaction
-
Araki, H.; Katoh, T.; Inoue, M. Iterative two-step strategy for C2- C4 ' linked poly-oxazole synthesis using Suzuki-Miyaura cross-coupling reaction. Tetrahedron Lett., 2007, 48, 3713-3717.
-
(2007)
Tetrahedron Lett
, vol.48
, pp. 3713-3717
-
-
Araki, H.1
Katoh, T.2
Inoue, M.3
-
48
-
-
42049096715
-
Convergent synthesis of contiguous tetra- and pentaoxazole ring systems related to some bioactive natural products
-
Chattopadhyay, S.K.; Biswas, S.; Ghosh, S.K. Convergent synthesis of contiguous tetra- and pentaoxazole ring systems related to some bioactive natural products. Synthesis, 2008, 1029-1032.
-
(2008)
Synthesis
, pp. 1029-1032
-
-
Chattopadhyay, S.K.1
Biswas, S.2
Ghosh, S.K.3
-
49
-
-
33748948394
-
Total synthesis of (R)-telomestatin
-
Doi, T.; Yoshida, M.; Shin-ya, K.; Takahashi, T. Total synthesis of (R)-telomestatin. Org. Lett., 2006, 8, 4165-4167.
-
(2006)
Org. Lett
, vol.8
, pp. 4165-4167
-
-
Doi, T.1
Yoshida, M.2
Shin-Ya, K.3
Takahashi, T.4
-
50
-
-
77957954774
-
-
WO 200248153
-
Yamada, S.; Shigeno, K.; Kitagawa, K.; Okajima, S.; Asao, T. WO 200248153, 2002.
-
(2002)
-
-
Yamada, S.1
Shigeno, K.2
Kitagawa, K.3
Okajima, S.4
Asao, T.5
-
51
-
-
33745132752
-
Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles
-
Minhas, G.S.; Pilch, D.S.; Kerrigan, J.E.; LaVoie, E.J.; Rice, J.E. Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles. Bioorg. Med. Chem. Lett., 2006, 16, 3891-3895.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 3891-3895
-
-
Minhas, G.S.1
Pilch, D.S.2
Kerrigan, J.E.3
Lavoie, E.J.4
Rice, J.E.5
-
52
-
-
34250878987
-
Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA
-
Barbieri, C.M.; Srinivasan, A.R.; Rzuczek, S.G.; Rice, J.E.; LaVoie, E.J.; Pilch, D.S. Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA. Nucleic Acids Res., 2007, 35, 3272-3286.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 3272-3286
-
-
Barbieri, C.M.1
Srinivasan, A.R.2
Rzuczek, S.G.3
Rice, J.E.4
Lavoie, E.J.5
Pilch, D.S.6
-
53
-
-
47649122998
-
-
Pilch, D.S.; Barbieri, C.M.; Rzuczek, S.G.; LaVoie, E.J.; Rice, J.E. Targeting human telomeric G-quadruplex DNA with oxazole-containing macrocyclic compounds. Biochimie, 2008, 90, 1233-1249.
-
(2008)
Targeting Human Telomeric G-quadruplex DNA With Oxazole-Containing Macrocyclic Compounds. Biochimie
, vol.90
, pp. 1233-1249
-
-
Pilch, D.S.1
Barbieri, C.M.2
Rzuczek, S.G.3
Lavoie, E.J.4
Rice, J.E.5
-
54
-
-
69249094213
-
G-quadruplex Stabilizer Induces M-phase Cell Cycle Arrest
-
Tsai, Y.C.; Qi, H.Y.; Lin, C.P.; Lin, R.K.; Kerrigan, J.E.; Rzuczek, S.G.; LaVoie, E.J.; Rice, J.E.; Pilch, D.S.; Lyu, Y.L.; Liu, L.F. A G-quadruplex Stabilizer Induces M-phase Cell Cycle Arrest. J. Biol. Chem., 2009, 284, 22535-22543.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 22535-22543
-
-
Tsai, Y.C.1
Qi, H.Y.2
Lin, C.P.3
Lin, R.K.4
Kerrigan, J.E.5
Rzuczek, S.G.6
Lavoie, E.J.7
Rice, J.E.8
Pilch, D.S.9
Lyu, Y.L.10
Liu, L.F.A.11
-
55
-
-
44849098127
-
Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency
-
Satyanarayana, M.; Rzuczek, S.G.; LaVoie, E.J.; Pilch, D.S.; Liu, A.; Liu, L.F.; Rice, J.E. Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency. Bioorg. Med. Chem. Lett., 2008, 18, 3802-3804.
-
(2008)
Bioorg. Med. Chem. Lett
, vol.18
, pp. 3802-3804
-
-
Satyanarayana, M.1
Rzuczek, S.G.2
Lavoie, E.J.3
Pilch, D.S.4
Liu, A.5
Liu, L.F.6
Rice, J.E.7
-
56
-
-
70350330210
-
G- quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer: Greater selectivity than monomer
-
Iida, K.; Tera, M.; Hirokawa, T.; Shin-ya, K.; Nagasawa, K. G- quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer: greater selectivity than monomer. Chem. Commun., 2009, 6481-6483.
-
(2009)
Chem. Commun
, pp. 6481-6483
-
-
Iida, K.1
Tera, M.2
Hirokawa, T.3
Shin-Ya, K.4
Nagasawa, K.5
-
57
-
-
38749119006
-
Lysinyl macrocyclic hexaoxazoles: Synthesis and selective G-quadruplex stabilizing properties
-
Rzuczek, S.G.; Pilch, D.S.; LaVoie, E.J.; Rice, J.E. Lysinyl macrocyclic hexaoxazoles: Synthesis and selective G-quadruplex stabilizing properties. Bioorg. Med. Chem. Lett., 2008, 18, 913-917.
-
(2008)
Bioorg. Med. Chem. Lett
, vol.18
, pp. 913-917
-
-
Rzuczek, S.G.1
Pilch, D.S.2
Lavoie, E.J.3
Rice, J.E.4
-
58
-
-
49649096112
-
Macrocyclic hexaoxazoles as sequence- and mode- selective G-quadruplex binders
-
Tera, M.; Ishizuka, H.; Takagi, M.; Suganuma, M.; Shin-Ya, K.; Nagasawa, K. Macrocyclic hexaoxazoles as sequence- and mode- selective G-quadruplex binders. Angew. Chem. Int. Ed., 2008, 47, 5557-5560.
-
(2008)
Angew. Chem. Int. Ed
, vol.47
, pp. 5557-5560
-
-
Tera, M.1
Ishizuka, H.2
Takagi, M.3
Suganuma, M.4
Shin-Ya, K.5
Nagasawa, K.6
-
59
-
-
77952065213
-
Macrocyclic hexaoxazoles: Influence of aminoalkyl substituents on RNA and DNA G- quadruplex stabilization and cytotoxicity
-
Satyanarayana, M.; Kim, Y.A.; Rzuczek, S.G.; Pilch, D.S.; Liu, A.A.; Liu, L.F.; Rice, J.E.; LaVoie, E.J. Macrocyclic hexaoxazoles: Influence of aminoalkyl substituents on RNA and DNA G- quadruplex stabilization and cytotoxicity. Bioorg. Med. Chem. Lett., 2010, 20, 3150-3154.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 3150-3154
-
-
Satyanarayana, M.1
Kim, Y.A.2
Rzuczek, S.G.3
Pilch, D.S.4
Liu, A.A.5
Liu, L.F.6
Rice, J.E.7
Lavoie, E.J.8
-
60
-
-
60349105930
-
Synthesis of a Potent G-Quadruplex- Binding Macrocyclic Heptaoxazole
-
Tera, M.; Lida, K.; Ishizuka, H.; Takagi, M.; Suganuma, M.; Doi, T.; Shin-ya, K.; Nagasawa, K. Synthesis of a Potent G-Quadruplex- Binding Macrocyclic Heptaoxazole. ChemBioChem, 2009, 10, 431.
-
(2009)
ChemBioChem
, vol.10
, pp. 431
-
-
Tera, M.1
Lida, K.2
Ishizuka, H.3
Takagi, M.4
Suganuma, M.5
Doi, T.6
Shin-Ya, K.7
Nagasawa, K.8
-
61
-
-
33750297406
-
Oxazole-based peptide macrocycles: A new class of G-quadruplex binding ligands
-
Jantos, K.; Rodriguez, R.; Ladame, S.; Shirude, P.S.; Balasubramanian, S. Oxazole-based peptide macrocycles: A new class of G-quadruplex binding ligands. J. Am. Chem. Soc., 2006, 128, 13662-13663.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 13662-13663
-
-
Jantos, K.1
Rodriguez, R.2
Ladame, S.3
Shirude, P.S.4
Balasubramanian, S.5
-
62
-
-
41949093057
-
Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry
-
Bugaut, A.; Jantos, K.; Wietor, J.L.; Rodriguez, R.; Sanders, J.K.M.; Balasubramanian, S. Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry. Angew. Chem. Int. Ed., 2008, 47, 2677-2680.
-
(2008)
Angew. Chem. Int. Ed
, vol.47
, pp. 2677-2680
-
-
Bugaut, A.1
Jantos, K.2
Wietor, J.L.3
Rodriguez, R.4
Sanders, J.K.M.5
Balasubramanian, S.6
-
63
-
-
55049135041
-
Selective extraction of G-quadruplex ligands from a rationally designed scaffold-based dynamic combinatorial library
-
Nielsen, M.C.; Ulven, T. Selective extraction of G-quadruplex ligands from a rationally designed scaffold-based dynamic combinatorial library. Chem. Eur. J., 2008, 14, 9487-9490.
-
(2008)
Chem. Eur. J
, vol.14
, pp. 9487-9490
-
-
Nielsen, M.C.1
Ulven, T.2
-
64
-
-
71849100513
-
Design, synthesis and evaluation of 4,7-diamino-1,10-phenanthroline G-quadruplex ligands
-
Nielsen, M.C.; Borch, J.; Ulven, T. Design, synthesis and evaluation of 4,7-diamino-1,10-phenanthroline G-quadruplex ligands. Bioorg. Med. Chem., 2009, 17, 8241-8246.
-
(2009)
Bioorg. Med. Chem
, vol.17
, pp. 8241-8246
-
-
Nielsen, M.C.1
Borch, J.2
Ulven, T.3
-
65
-
-
72949092489
-
Luedtke, N.W. Guanidinium-modified phthalocyanines as high-affinity g- quadruplex fluorescent probes and transcriptional regulators
-
Alzeer, J.; Vummidi, B.R.; Roth, P.J.C.; Luedtke, N.W. Guanidinium-modified phthalocyanines as high-affinity g- quadruplex fluorescent probes and transcriptional regulators. Angew. Chem. Int. Ed., 2009, 48, 9362-9365.
-
(2009)
Angew. Chem. Int. Ed
, vol.48
, pp. 9362-9365
-
-
Alzeer, J.1
Vummidi, B.R.2
Roth, P.J.C.3
-
66
-
-
77952045784
-
Macrocyclic Pyridyl Polyoxazoles: Selective RNA and DNA G- Quadruplex Ligands as Antitumor Agents
-
Rzuczek, S.G.; Pilch, D.S.; Liu, A.; Liu, L.; LaVoie, E.J.; Rice, J.E. Macrocyclic Pyridyl Polyoxazoles: Selective RNA and DNA G- Quadruplex Ligands as Antitumor Agents. J. Med. Chem., 2010, 53, 3632-3644.
-
(2010)
J. Med. Chem
, vol.53
, pp. 3632-3644
-
-
Rzuczek, S.G.1
Pilch, D.S.2
Liu, A.3
Liu, L.4
Lavoie, E.J.5
Rice, J.E.6
-
67
-
-
36148978139
-
Furan based cyclic Oligopeptides selectively target G-quadruplex
-
Chakraborty, T.K.; Arora, A.; Roy, S.; Kumar, N.; Maiti, S. Furan based cyclic Oligopeptides selectively target G-quadruplex. J. Med. Chem., 2007, 50, 5539-5542.
-
(2007)
J. Med. Chem
, vol.50
, pp. 5539-5542
-
-
Chakraborty, T.K.1
Arora, A.2
Roy, S.3
Kumar, N.4
Maiti, S.5
-
68
-
-
34848865663
-
Macrocyclic and helical oligoamides as a new class of g-quadruplex ligands
-
Shirude, P.S.; Gillies, E.R.; Ladame, S.; Godde, F.; Shin-Ya, K.; Huc, I.; Balasubramanian, S. Macrocyclic and helical oligoamides as a new class of g-quadruplex ligands. J. Am. Chem. Soc., 2007, 129, 11890-11891.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 11890-11891
-
-
Shirude, P.S.1
Gillies, E.R.2
Ladame, S.3
Godde, F.4
Shin-Ya, K.5
Huc, I.6
Balasubramanian, S.7
-
69
-
-
69849087045
-
Bound by a Synthetic Ligand is Highly Dynamic
-
Jena, P.V.; Shirude, P.S.; Okumus, B.; Laxmi-Reddy, K.; Godde, F.; Huc, I.; Balasubramanian, S.; Ha, T. G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic. J. Am. Chem. Soc., 2009, 131, 12522-12523.
-
(2009)
J. Am. Chem. Soc
, vol.131
, pp. 12522-12523
-
-
Jena, P.V.1
Shirude, P.S.2
Okumus, B.3
Laxmi-Reddy, K.4
Godde, F.5
Huc, I.6
Balasubramanian, S.7
Ha, T.8
G-Quadruplex, D.N.A.9
-
70
-
-
0032495774
-
Cationic porphyrins as telomerase inhibitors: The interaction of tetra-(N-methyl-4-pyridyl)porphine with quadruplex DNA
-
Wheelhouse, R.T.; Sun, D.K.; Han, H.Y.; Han, F.X.G.; Hurley, L.H. Cationic porphyrins as telomerase inhibitors: the interaction of tetra-(N-methyl-4-pyridyl)porphine with quadruplex DNA. J. Am. Chem. Soc., 1998, 120, 3261-3262.
-
(1998)
J. Am. Chem. Soc
, vol.120
, pp. 3261-3262
-
-
Wheelhouse, R.T.1
Sun, D.K.2
Han, H.Y.3
Han, F.X.G.4
Hurley, L.H.5
-
71
-
-
0033594341
-
Interactions of TMPyP4 and TMPyP2 with quadruplex DNA. Structural basis for the differential effects on telomerase inhibition
-
Han, F.X.G.; Wheelhouse, R.T.; Hurley, L.H. Interactions of TMPyP4 and TMPyP2 with quadruplex DNA. Structural basis for the differential effects on telomerase inhibition. J. Am. Chem. Soc., 1999, 121, 3561-3570.
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 3561-3570
-
-
Han, F.X.G.1
Wheelhouse, R.T.2
Hurley, L.H.3
-
72
-
-
0033083378
-
Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells
-
Izbicka, E.; Wheelhouse, R.T.; Raymond, E.; Davidson, K.K.; Lawrence, R.A.; Sun, D.Y.; Windle, B.E.; Hurley, L.H.; Von Hoff, D.D. Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells. Cancer Res., 1999, 59, 639-644.
-
(1999)
Cancer Res
, vol.59
, pp. 639-644
-
-
Izbicka, E.1
Wheelhouse, R.T.2
Raymond, E.3
Davidson, K.K.4
Lawrence, R.A.5
Sun, D.Y.6
Windle, B.E.7
Hurley, L.H.8
von Hoff, D.D.9
-
73
-
-
0035924232
-
Quadruplex- interactive agents as telomerase inhibitors: Synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase
-
Shi, D.F.; Wheelhouse, R.T.; Sun, D.Y.; Hurley, L.H. Quadruplex- interactive agents as telomerase inhibitors: Synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase. J. Med. Chem., 2001, 44, 4509-4523.
-
(2001)
J. Med. Chem
, vol.44
, pp. 4509-4523
-
-
Shi, D.F.1
Wheelhouse, R.T.2
Sun, D.Y.3
Hurley, L.H.4
-
74
-
-
0642287888
-
Telomerase inhibition and cell growth arrest by G- quadruplex interactive agent in multiple myeloma
-
Shammas, M.A.; Reis, R.J.S.; Akiyama, M.; Koley, H.; Chauhan, D.; Hideshima, T.; Goyal, R.K.; Hurley, L.H.; Anderson, K.C.; Munshi, N.C. Telomerase inhibition and cell growth arrest by G- quadruplex interactive agent in multiple myeloma. Mol. Cancer Ther., 2003, 2, 825-833.
-
(2003)
Mol. Cancer Ther
, vol.2
, pp. 825-833
-
-
Shammas, M.A.1
Reis, R.J.S.2
Akiyama, M.3
Koley, H.4
Chauhan, D.5
Hideshima, T.6
Goyal, R.K.7
Hurley, L.H.8
Anderson, K.C.9
Munshi, N.C.10
-
75
-
-
0033541133
-
Intercalative G- tetraplex stabilization of telomeric DNA by a cationic porphyrin
-
Haq, I.; Trent, J.O.; Chowdhry, B.Z.; Jenkins, T.C. Intercalative G- tetraplex stabilization of telomeric DNA by a cationic porphyrin. J. Am. Chem. Soc., 1999, 121, 1768-1779.
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 1768-1779
-
-
Haq, I.1
Trent, J.O.2
Chowdhry, B.Z.3
Jenkins, T.C.4
-
76
-
-
65649099650
-
Evidence for the binding mode of porphyrins to G-quadruplex DNA. Phys
-
Wei, C.Y.; Jia, G.Q.; Zhou, J.; Han, G.Y.; Li, C. Evidence for the binding mode of porphyrins to G-quadruplex DNA. Phys. Chem. Chem. Phys., 2009, 11, 4025-4032.
-
(2009)
Chem. Chem. Phys
, vol.11
, pp. 4025-4032
-
-
Wei, C.Y.1
Jia, G.Q.2
Zhou, J.3
Han, G.Y.4
Li, C.5
-
77
-
-
59449107619
-
Ligand Binding to Tandem G Quadruplexes from Human Telomeric DNA
-
Bai, L.P.; Hagihara, M.; Jiang, Z.H.; Nakatani, K. Ligand Binding to Tandem G Quadruplexes from Human Telomeric DNA. ChemBioChem, 2008, 9, 2583-2587.
-
(2008)
ChemBioChem
, vol.9
, pp. 2583-2587
-
-
Bai, L.P.1
Hagihara, M.2
Jiang, Z.H.3
Nakatani, K.4
-
78
-
-
72449126172
-
Shedding Light on the Interaction between TMPyP4 and Human Telomeric Quadruplexes
-
Martino, L.; Pagano, B.; Fotticchia, I.; Neidle, S.; Giancola, C. Shedding Light on the Interaction between TMPyP4 and Human Telomeric Quadruplexes. J. Phys. Chem. B, 2009, 113, 14779-14786.
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 14779-14786
-
-
Martino, L.1
Pagano, B.2
Fotticchia, I.3
Neidle, S.4
Giancola, C.5
-
79
-
-
33744962025
-
Formation of a complex of 5,10,15,20-tetrakis(N-methylpyridinium-4-yl)-21H, 23H-porphyrin with G-quadruplex DNA
-
Mita, H.; Ohyama, T.; Tanaka, Y.; Yamamoto, Y. Formation of a complex of 5,10,15,20-tetrakis(N-methylpyridinium-4-yl)-21H, 23H-porphyrin with G-quadruplex DNA. Biochemistry, 2006, 45, 6765-6772.
-
(2006)
Biochemistry
, vol.45
, pp. 6765-6772
-
-
Mita, H.1
Ohyama, T.2
Tanaka, Y.3
Yamamoto, Y.4
-
80
-
-
33744772345
-
A spectroscopic study on the interactions of porphyrin with G-quadruplex DNAs
-
Wei, C.Y.; Jia, G.Q.; Yuan, J.L.; Feng, Z.C.; Li, C. A spectroscopic study on the interactions of porphyrin with G-quadruplex DNAs. Biochemistry, 2006, 45, 6681-6691.
-
(2006)
Biochemistry
, vol.45
, pp. 6681-6691
-
-
Wei, C.Y.1
Jia, G.Q.2
Yuan, J.L.3
Feng, Z.C.4
Li, C.5
-
81
-
-
68849103475
-
Conformational conversion of DNA G-quadruplex induced by a cationic porphyrin
-
Zhang, H.J.; Xiao, X.; Wang, P.; Pang, S.P.; Qu, F.; Ai, X.C.; Zhang, J.P. Conformational conversion of DNA G-quadruplex induced by a cationic porphyrin. Spectrochim. Acta A, 2009, 74, 243-247.
-
(2009)
Spectrochim. Acta A
, vol.74
, pp. 243-247
-
-
Zhang, H.J.1
Xiao, X.2
Wang, P.3
Pang, S.P.4
Qu, F.5
Ai, X.C.6
Zhang, J.P.7
-
82
-
-
48549090739
-
Spectroscopic study on the binding of a cationic porphyrin to DNA G-quadruplex under different K+ concentrations
-
Zhang, H.J.; Wang, X.F.; Wang, P.; Ai, X.C.; Zhang, J.P. Spectroscopic study on the binding of a cationic porphyrin to DNA G-quadruplex under different K+ concentrations. Photochem. Photobiol. Sci., 2008, 7, 948-955.
-
(2008)
Photochem. Photobiol. Sci
, vol.7
, pp. 948-955
-
-
Zhang, H.J.1
Wang, X.F.2
Wang, P.3
Ai, X.C.4
Zhang, J.P.5
-
83
-
-
0033534146
-
Sequence and structural selectivity of nucleic acid binding ligands
-
Ren, J.S.; Chaires, J.B. Sequence and structural selectivity of nucleic acid binding ligands. Biochemistry, 1999, 38, 16067-16075.
-
(1999)
Biochemistry
, vol.38
, pp. 16067-16075
-
-
Ren, J.S.1
Chaires, J.B.2
-
84
-
-
33847675742
-
Structural basis for binding of porphyrin to human telomeres
-
Parkinson, G.N.; Ghosh, R.; Neidle, S. Structural basis for binding of porphyrin to human telomeres. Biochemistry, 2007, 46, 2390-2397.
-
(2007)
Biochemistry
, vol.46
, pp. 2390-2397
-
-
Parkinson, G.N.1
Ghosh, R.2
Neidle, S.3
-
85
-
-
33644833219
-
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter
-
Phan, A.T.; Kuryavyi, V.; Gaw, H.Y.; Patel, D.J. Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nat. Chem. Biol., 2005, 1, 167-173.
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 167-173
-
-
Phan, A.T.1
Kuryavyi, V.2
Gaw, H.Y.3
Patel, D.J.4
-
86
-
-
49149107193
-
Effect of loop orientation on quadruplex- TMPyP4 interaction
-
Arora, A.; Maiti, S. Effect of loop orientation on quadruplex- TMPyP4 interaction. J. Phys. Chem. B, 2008, 112, 8151-8159.
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 8151-8159
-
-
Arora, A.1
Maiti, S.2
-
87
-
-
33746520122
-
Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element
-
Hurley, L.H.; Von Hoff, D.D.; Siddiqui-Jain, A.; Yang, D.Z. Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element. Semin. Oncol., 2006, 33, 498-512.
-
(2006)
Semin. Oncol
, vol.33
, pp. 498-512
-
-
Hurley, L.H.1
von Hoff, D.D.2
Siddiqui-Jain, A.3
Yang, D.Z.4
-
88
-
-
0037015078
-
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
-
Siddiqui-Jain, A.; Grand, C.L.; Bearss, D.J.; Hurley, L.H. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 11593-11598.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 11593-11598
-
-
Siddiqui-Jain, A.1
Grand, C.L.2
Bearss, D.J.3
Hurley, L.H.4
-
89
-
-
39149144832
-
Antitumor activity of G-quadruplex- interactive agent TMPyP4 in K562 leukemic cells
-
Mikami-Terao, Y.; Akiyama, M.; Yuza, Y.; Yanagisawa, T.; Yamada, O.; Yamada, H. Antitumor activity of G-quadruplex- interactive agent TMPyP4 in K562 leukemic cells. Cancer Lett., 2008, 261, 226-234.
-
(2008)
Cancer Lett
, vol.261
, pp. 226-234
-
-
Mikami-Terao, Y.1
Akiyama, M.2
Yuza, Y.3
Yanagisawa, T.4
Yamada, O.5
Yamada, H.6
-
90
-
-
65749090612
-
Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand
-
del Toro, M.; Bucek, P.; Avino, A.; Jaumot, J.; Gonzalez, C.; Eritja, R.; Gargallo, R. Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand. Biochimie, 2009, 91, 894-902.
-
(2009)
Biochimie
, vol.91
, pp. 894-902
-
-
del Toro, M.1
Bucek, P.2
Avino, A.3
Jaumot, J.4
Gonzalez, C.5
Eritja, R.6
Gargallo, R.7
-
91
-
-
67650436065
-
Antitumor activity of TMPyP4 interacting G-quadruplex in retinoblastoma cell lines
-
Mikami-Terao, Y.; Akiyama, M.; Yuza, Y.; Yanagisawa, T.; Yamada, O.; Kawano, T.; Agawa, M.; Ida, H.; Yamada, H. Antitumor activity of TMPyP4 interacting G-quadruplex in retinoblastoma cell lines. Exp. Eye Res., 2009, 89, 200-208.
-
(2009)
Exp. Eye Res
, vol.89
, pp. 200-208
-
-
Mikami-Terao, Y.1
Akiyama, M.2
Yuza, Y.3
Yanagisawa, T.4
Yamada, O.5
Kawano, T.6
Agawa, M.7
Ida, H.8
Yamada, H.9
-
92
-
-
48649085981
-
Study on the interaction of porphyrin with G-quadruplex DNAs
-
Wei, C.; Han, G.; Jia, G.; Zhou, J.; Li, C. Study on the interaction of porphyrin with G-quadruplex DNAs. Biophys. Chem., 2008, 137, 19-23.
-
(2008)
Biophys. Chem
, vol.137
, pp. 19-23
-
-
Wei, C.1
Han, G.2
Jia, G.3
Zhou, J.4
Li, C.5
-
93
-
-
65749115962
-
The binding mode of porphyrins with cation side arms to (TG(4)T)4 G- quadruplex Spectroscopic evidence
-
Wei, C.Y.; Wang, L.H.; Jia, G.Q.; Zhou, J.; Han, G.Y.; Li, C. The binding mode of porphyrins with cation side arms to (TG(4)T)4 G- quadruplex: Spectroscopic evidence. Biophys. Chem., 2009, 143, 79-84.
-
(2009)
Biophys. Chem
, vol.143
, pp. 79-84
-
-
Wei, C.Y.1
Wang, L.H.2
Jia, G.Q.3
Zhou, J.4
Han, G.Y.5
Li, C.6
-
94
-
-
0032529641
-
Fluorescent dyes specific for quadruplex DNA
-
Arthanari, H.; Basu, S.; Kawano, T.L.; Bolton, P.H. Fluorescent dyes specific for quadruplex DNA. Nucleic Acids Res., 1998, 26, 3724-3728.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3724-3728
-
-
Arthanari, H.1
Basu, S.2
Kawano, T.L.3
Bolton, P.H.4
-
95
-
-
0035870569
-
Substrate-specific inhibition of RecQ helicase
-
Wu, X.; Maizels, N. Substrate-specific inhibition of RecQ helicase. Nucleic Acids Res., 2001, 29, 1765-1771.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 1765-1771
-
-
Wu, X.1
Maizels, N.2
-
96
-
-
33747168762
-
A phenol quaternary ammonium porphyrin as a potent telomerase inhibitor by selective interaction with quadruplex DNA
-
Wang, P.; Ren, L.; He, H.P.; Liang, F.; Zhou, X.; Tan, Z. A phenol quaternary ammonium porphyrin as a potent telomerase inhibitor by selective interaction with quadruplex DNA. ChemBioChem, 2006, 7, 1155-1159.
-
(2006)
ChemBioChem
, vol.7
, pp. 1155-1159
-
-
Wang, P.1
Ren, L.2
He, H.P.3
Liang, F.4
Zhou, X.5
Tan, Z.6
-
97
-
-
50949132208
-
Studies on the interactions of a novel ruthenium(II) complex with G-quadruplex DNA
-
Mei, W.J.; Wei, X.Y.; Liu, Y.J.; Wang, B. Studies on the interactions of a novel ruthenium(II) complex with G-quadruplex DNA. Transition Met. Chem., 2008, 33, 907-910.
-
(2008)
Transition Met. Chem
, vol.33
, pp. 907-910
-
-
Mei, W.J.1
Wei, X.Y.2
Liu, Y.J.3
Wang, B.4
-
98
-
-
33846947206
-
G-quadruplex ligand with 10000-fold selectivity over duplex DNA
-
Dixon, I.M.; Lopez, F.; Tejera, A.M.; Esteve, J.P.; Blasco, M.A.; Pratviel, G.; Meunier, B. A G-quadruplex ligand with 10000-fold selectivity over duplex DNA. J. Am. Chem. Soc., 2007, 129, 1502-1503.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 1502-1503
-
-
Dixon, I.M.1
Lopez, F.2
Tejera, A.M.3
Esteve, J.P.4
Blasco, M.A.5
Pratviel, G.6
Meunier, B.A.7
-
99
-
-
20044382992
-
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure
-
Seenisamy, J.; Bashyam, S.; Gokhale, V.; Vankayalapati, H.; Sun, D.; Siddiqui-Jain, A.; Streiner, N.; Shin-ya, K.; White, E.; Wilson, W.D.; Hurley, L.H. Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure. J. Am. Chem. Soc., 2005, 127, 2944-2959.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 2944-2959
-
-
Seenisamy, J.1
Bashyam, S.2
Gokhale, V.3
Vankayalapati, H.4
Sun, D.5
Siddiqui-Jain, A.6
Streiner, N.7
Shin-Ya, K.8
White, E.9
Wilson, W.D.10
Hurley, L.H.11
-
100
-
-
34547607293
-
Cationic corrole derivatives: A new family of G-quadruplex inducing and stabilizing ligands
-
Fu, B.Q.; Huang, J.; Ren, L.; Weng, X.C.; Zhou, Y.Y.; Du, Y.H.; Wu, X.J.; Zhou, X.; Yang, G.F. Cationic corrole derivatives: a new family of G-quadruplex inducing and stabilizing ligands. Chem. Commun., 2007, 3264-3266.
-
(2007)
Chem. Commun
, pp. 3264-3266
-
-
Fu, B.Q.1
Huang, J.2
Ren, L.3
Weng, X.C.4
Zhou, Y.Y.5
Du, Y.H.6
Wu, X.J.7
Zhou, X.8
Yang, G.F.9
-
101
-
-
33747882880
-
Synthesis and G-quadruplex binding studies of new 4-N- methylpyridinium porphyrins
-
Goncalves, D.P.N.; Ladame, S.; Balasubramanian, S.; Sanders, J.K.M. Synthesis and G-quadruplex binding studies of new 4-N- methylpyridinium porphyrins. Org. Biomol. Chem., 2006, 4, 3337-3342.
-
(2006)
Org. Biomol. Chem
, vol.4
, pp. 3337-3342
-
-
Goncalves, D.P.N.1
Ladame, S.2
Balasubramanian, S.3
Sanders, J.K.M.4
-
102
-
-
55049129800
-
Cationic Metal-Corrole Complexes: Design, Synthesis, and Properties of Guanine-Quadruplex Stabilizers
-
Fu, B.Q.; Zhang, D.; Weng, X.C.; Zhang, M.; Ma, H.; Ma, Y.Z.; Zhou, X. Cationic Metal-Corrole Complexes: Design, Synthesis, and Properties of Guanine-Quadruplex Stabilizers. Chem. Eur. J, 2008, 14, 9431-9441.
-
(2008)
Chem. Eur. J
, vol.14
, pp. 9431-9441
-
-
Fu, B.Q.1
Zhang, D.2
Weng, X.C.3
Zhang, M.4
Ma, H.5
Ma, Y.Z.6
Zhou, X.7
-
103
-
-
33644653403
-
Cyclo n pyrroles: Size and site-specific binding to G-quadruplexes
-
Baker, E.S.; Lee, J.T.; Sessler, J.L.; Bowers, M.T. Cyclo n pyrroles: Size and site-specific binding to G-quadruplexes. J. Am. Chem. Soc., 2006, 128, 2641-2648.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 2641-2648
-
-
Baker, E.S.1
Lee, J.T.2
Sessler, J.L.3
Bowers, M.T.4
-
104
-
-
34250837616
-
Quaternary ammonium zinc phthalocyanine: Inhibiting telomerase by stabilizing G quadruplexes and inducing G-quadruplex structure transition and formation
-
Ren, L.G.; Zhang, A.M.; Huang, J.; Wang, P.; Weng, X.C.; Zhang, L.X.; Liang, F.; Tan, Z.; Zhou, X. Quaternary ammonium zinc phthalocyanine: Inhibiting telomerase by stabilizing G quadruplexes and inducing G-quadruplex structure transition and formation. ChemBioChem, 2007, 8, 775-780.
-
(2007)
ChemBioChem
, vol.8
, pp. 775-780
-
-
Ren, L.G.1
Zhang, A.M.2
Huang, J.3
Wang, P.4
Weng, X.C.5
Zhang, L.X.6
Liang, F.7
Tan, Z.8
Zhou, X.9
-
105
-
-
38049024723
-
Synthesis and evaluation of cationic phthalocyanine derivatives as potential inhibitors of telomerase
-
Zhang, L.X.; Huang, J.; Ren, L.; Bai, M.H.; Wu, L.; Zhai, B.P.; Zhou, X. Synthesis and evaluation of cationic phthalocyanine derivatives as potential inhibitors of telomerase. Bioorg. Med. Chem., 2008, 16, 303-312.
-
(2008)
Bioorg. Med. Chem
, vol.16
, pp. 303-312
-
-
Zhang, L.X.1
Huang, J.2
Ren, L.3
Bai, M.H.4
Wu, L.5
Zhai, B.P.6
Zhou, X.7
-
106
-
-
75149116665
-
Cellular uptake and binding of guanidine- modified phthalocyanines to KRAS/HRAS G-quadruplexes
-
Membrino, A.; Paramasivam, M.; Cogoi, S.; Alzeer, J.; Luedtke, N.W.; Xodo, L.E. Cellular uptake and binding of guanidine- modified phthalocyanines to KRAS/HRAS G-quadruplexes. Chem. Commun., 2010, 46, 625-627.
-
(2010)
Chem. Commun
, vol.46
, pp. 625-627
-
-
Membrino, A.1
Paramasivam, M.2
Cogoi, S.3
Alzeer, J.4
Luedtke, N.W.5
Xodo, L.E.6
-
107
-
-
33751089304
-
Tetramethylpyridiniumporphyrazines - a new class of G- quadruplex inducing and stabilising ligands
-
Goncalves, D.P.N.; Rodriguez, R.; Balasubramanian, S.; Sanders, J.K.M. Tetramethylpyridiniumporphyrazines - a new class of G- quadruplex inducing and stabilising ligands. Chem. Commun., 2006, 4685-4687.
-
(2006)
Chem. Commun
, pp. 4685-4687
-
-
Goncalves, D.P.N.1
Rodriguez, R.2
Balasubramanian, S.3
Sanders, J.K.M.4
-
108
-
-
34447534247
-
Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction
-
Rodriguez, R.; Pantos, G.D.; Goncalves, D.P.N.; Sanders, J.K.M.; Balasubramanian, S. Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction. Angew. Chem. Int. Ed., 2007, 46, 5405-5407.
-
(2007)
Angew. Chem. Int. Ed
, vol.46
, pp. 5405-5407
-
-
Rodriguez, R.1
Pantos, G.D.2
Goncalves, D.P.N.3
Sanders, J.K.M.4
Balasubramanian, S.5
-
109
-
-
46449115901
-
The exploration of macrocycles for drug discovery - an underexploited structural class. Nat
-
Driggers, E.M.; Hale, S.P.; Lee, J.; Terrett, N.K. The exploration of macrocycles for drug discovery - an underexploited structural class. Nat. Rev. Drug. Discov., 2008, 7, 608-624.
-
(2008)
Rev. Drug. Discov
, vol.7
, pp. 608-624
-
-
Driggers, E.M.1
Hale, S.P.2
Lee, J.3
Terrett, N.K.4
-
110
-
-
77957947673
-
One ring to bind them All"-Part I: The efficiency of the macrocyclic scaffold for G-quadruplex DNA recognition
-
article ID 525862, doi:10.4061/2010/525862
-
Monchaud, D.; Granzhan, A.; Saettel, N.; Guédin, A.; Mergny, J.- L.; Telaude-Fichou, M.-P. One ring to bind them All"-Part I: The efficiency of the macrocyclic scaffold for G-quadruplex DNA recognition. J. Nucleic Acids, 2010, article ID 525862, doi:10.4061/2010/525862.
-
(2010)
J. Nucleic Acids
-
-
Monchaud, D.1
Granzhan, A.2
Saettel, N.3
Guédin, A.4
Mergny J.-, L.5
Telaude-Fichou, M.-P.6
-
111
-
-
77957967704
-
One Ring to bind them All"-Part II: Identification of promising G-quadruplex ligands by screening of cyclophane-type macrocycles
-
article ID 460561, doi:10.4061/2010/460561
-
Granzhan, A.; Monchaud, D.; Saettel, N.; Guédin, A.; Mergny, J.- L.; Teulade-Fichou, M.-P. One Ring to bind them All"-Part II: identification of promising G-quadruplex ligands by screening of cyclophane-type macrocycles. J. Nucleic Acids, 2010, article ID 460561, doi:10.4061/2010/460561.
-
(2010)
J. Nucleic Acids
-
-
Granzhan, A.1
Monchaud, D.2
Saettel, N.3
Guédin, A.4
Mergny J.-, L.5
Teulade-Fichou, M.-P.6
-
112
-
-
77957942511
-
Synthesis of macrocyclic hexaoxazole (6OTD) Dimers, containing guanidine and amine functionalized side chains, and an evaluation of their telomeric G4 stabilizing properties
-
article ID 217627, doi:10.4061/2010/217627
-
Iida, K.; Tera, M.; Hirokawa, T.; Shin-ya, K.; Nagasawa, K. Synthesis of macrocyclic hexaoxazole (6OTD) Dimers, containing guanidine and amine functionalized side chains, and an evaluation of their telomeric G4 stabilizing properties. J. Nucleic Acids, 2010, article ID 217627, doi:10.4061/2010/217627.
-
(2010)
J. Nucleic Acids
-
-
Iida, K.1
Tera, M.2
Hirokawa, T.3
Shin-Ya, K.4
Nagasawa, K.5
-
113
-
-
77953185961
-
Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole
-
Tera, M.; Iida, K.; Ikebukuro, K.; Seimiya, H.; Shin-Ya, K.; Nagasawa, K. Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole. Org. Biomol. Chem., 2010, 8, 2749-2755.
-
(2010)
Org. Biomol. Chem
, vol.8
, pp. 2749-2755
-
-
Tera, M.1
Iida, K.2
Ikebukuro, K.3
Seimiya, H.4
Shin-Ya, K.5
Nagasawa, K.6
-
114
-
-
77949831452
-
A chiral wedge molecule inhibits telomerase activity
-
Shinohara, K.-I.; Sannohe, Y.; Kaieda, S.; Tanaka, K.-i.; Osuga, H.; Tahara, H.; Xu, Y.; Kawase, T.; Bando, T.; Sugiyama, H. A chiral wedge molecule inhibits telomerase activity. J. Am. Chem. Soc., 2010, 132, 3778-3782.
-
(2010)
J. Am. Chem. Soc
, vol.132
, pp. 3778-3782
-
-
Shinohara, K.-I.1
Sannohe, Y.2
Kaieda, S.3
Tanaka, K.-I.4
Osuga, H.5
Tahara, H.6
Xu, Y.7
Kawase, T.8
Bando, T.9
Sugiyama, H.10
-
115
-
-
77955423929
-
Furan based cyclic homo-oligopeptides bind G-quadruplex selectively and repress c-MYC transcription
-
Agarwal, T.; Roy, S.; Chakraborty, T.K.; Maiti, S. Furan based cyclic homo-oligopeptides bind G-quadruplex selectively and repress c-MYC transcription. Bioorg. Med. Chem. Lett., 2010, 20, 4346-4349.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 4346-4349
-
-
Agarwal, T.1
Roy, S.2
Chakraborty, T.K.3
Maiti, S.4
|