Synthesis and evaluation of cationic phthalocyanine derivatives as potential inhibitors of telomerase

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 1, 2008, Pages 303-312

  Zhang, Lixia ^a   Huang, Jing ^a   Ren, Lige ^a   Bai, Minghui ^a   Wu, Lin ^a   Zhai, Baoping ^a   Zhou, Xiang ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

G quadruplex; Phthalocyanine; Telomerase inhibitor

Indexed keywords

CATION; DNA; DNA POLYMERASE; PHTHALOCYANINE DERIVATIVE; TELOMERASE; TELOMERASE INHIBITOR;

ARTICLE; CIRCULAR DICHROISM; DNA SYNTHESIS INHIBITION; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; IC 50; STRUCTURE ACTIVITY RELATION; TELOMERE; TELOMERIC REPEAT AMPLIFICATION PROTOCOL;

CIRCULAR DICHROISM; ENZYME INHIBITORS; G-QUADRUPLEXES; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; STRUCTURE-ACTIVITY RELATIONSHIP; TELOMERASE; TEMPERATURE;

EID: 38049024723     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.09.037     Document Type: Article

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