Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA

Nucleic Acids Research

Volumn 35, Issue 10, 2007, Pages 3272-3286

  Barbieri, Christopher M ^a   Srinivasan, Annankoil R ^a   Rzuczek, Suzanne G ^b   Rice, Joseph E ^b   LaVoie, Edmond J ^b,c   Pilch, Daniel S ^a,c,d  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ANTINEOPLASTIC AGENT; DNA; MACROCYCLIC COMPOUND; OLIGONUCLEOTIDE; OXAZOLE DERIVATIVE; POTASSIUM ION; TELOMESTATIN; 2 AMINOPURINE; LIGAND; QUADRUPLEX DNA; UNCLASSIFIED DRUG;

ABSORPTION SPECTROPHOTOMETRY; ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG TARGETING; ENERGY TRANSFER; ENTROPY; FLUORESCENCE SPECTROSCOPY; INTERCALATION COMPLEX; MATHEMATICAL COMPUTING; PRIORITY JOURNAL; STEADY STATE; STOICHIOMETRY; TELOMERE; TEMPERATURE DEPENDENCE; THERMODYNAMICS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; HUMAN; METABOLISM; SPECTROFLUOROMETRY;

2-AMINOPURINE; ADENINE; ANTINEOPLASTIC AGENTS; BINDING SITES; DNA; ENTROPY; HUMANS; LIGANDS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OXAZOLES; SPECTROMETRY, FLUORESCENCE; TELOMERE;

EID: 34250878987     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm188     Document Type: Article

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