A G-quadruplex stabilizer induces M-phase cell cycle arrest

Journal of Biological Chemistry

Volumn 284, Issue 34, 2009, Pages 22535-22543

  Tsai, Yuan Chin ^a   Qi, Haiyan ^a   Lin, Chao Po ^a   Lin, Ren Kuo ^a   Kerrigan, John E ^b   Rzuczek, Suzanne G ^c,d   LaVoie, Edmond J ^c,d   Rice, Joseph E ^c,d   Pilch, Daniel S ^a   Lyu, Yi Lisa ^a   Liu, Leroy F ^a,e  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^c Universidad de Rutgers   (United States)

^d RUTGERS UNIVERSITY   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-PROLIFERATIVE; ANTI-TUMOR ACTIVITIES; ANTIPROLIFERATIVE ACTIVITIES; APOPTOSIS; APOPTOTIC ACTIVITY; BINDING ACTIVITIES; CELL-CYCLE ARREST; CELL-CYCLE PROGRESSION; CELLULAR EFFECTS; DNA CONTENT; EXPRESSION LEVELS; FIBER ASSEMBLIES; G-QUADRUPLEXES; HISTONE H3; INHIBITORY EFFECT; MITOTIC INDEX; MODE OF ACTION; PHASE ARREST; SINGLE-STRANDED DNA; SYNTHETIC ANALOGS; TELOMERASE; TELOMERE FUNCTION; TELOMESTATIN; TIME-LAPSE MICROSCOPY;

BINDING SITES; CELL DEATH; CHROMOSOMES; NUCLEIC ACIDS;

CELL MEMBRANES;

AURORA A KINASE; CASPASE; GUANINE QUADRUPLEX; GUANINE QUADRUPLEX STABILIZER HXDV; HISTONE H3; OXAZOLE DERIVATIVE; TELOMERASE; TELOMESTATIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CENTROSOME; CONTROLLED STUDY; CYTOTOXICITY; DNA CONTENT; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; G-QUADRUPLEXES; HUMANS; MACROCYCLIC COMPOUNDS; MICROSCOPY; TELOMERASE;

EID: 69249094213     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.020230     Document Type: Article

References (52)

1. Parkinson, G. N., Lee, M. P., and Neidle, S. (2002) Nature 417, 876-880
2. Patel, D. J., Phan, A. T., and Kuryavyi, V. (2007) Nucleic Acids Res. 35, 7429-7455
3. Schaffitzel, C., Berger, I., Postberg, J., Hanes, J., Lipps, H. J., and Plückthun, A. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 8572-8577
4. Chang, C. C., Chu, J. F., Kao, F. J., Chiu, Y. C., Lou, P. J., Chen, H. C., and Chang, T. C. (2006) Anal. Chem. 78, 2810-2815
5. Horard, B., and Gilson, E. (2008) Nat. Cell Biol. 10, 113-115
6. Siddiqui-Jain, A., Grand, C. L., Bearss, D. J., and Hurley, L. H. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 11593-11598
7. Didiot, M. C., Tian, Z., Schaeffer, C., Subramanian, M., Mandel, J. L., and Moine, H. (2008) Nucleic Acids Res. 36, 4902-4912
8. Giraldo, R., and Rhodes, D. (1994) EMBO J. 13, 2411-2420
9. Mohaghegh, P., Karow, J. K., Brosh, R. M., Jr., Bohr, V. A., and Hickson, I. D. (2001) Nucleic Acids Res. 29, 2843-2849
10. Sun, H., Yabuki, A., and Maizels, N. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 12444-12449
11. Gomez, D., Wenner, T., Brassart, B., Douarre, C., O'Donohue, M. F., El Khoury, V., Shin-Ya, K., Morjani, H., Trentesaux, C., and Riou, J. F. (2006) J. Biol. Chem. 281, 38721-38729
12. Tauchi, T., Shin-ya, K., Sashida, G., Sumi, M., Okabe, S., Ohyashiki, J. H., and Ohyashiki, K. (2006) Oncogene 25, 5719-5725
13. Phatak, P., Cookson, J. C., Dai, F., Smith, V., Gartenhaus, R. B., Stevens, M. F., and Burger, A. M. (2007) Br. J. Cancer 96, 1223-1233
14. Gowan, S. M., Harrison, J. R., Patterson, L., Valenti, M., Read, M. A., Neidle, S., and Kelland, L. R. (2002) Mol. Pharmacol. 61, 1154-1162
15. Pilch, D. S., Barbieri, C. M., Rzuczek, S. G., Lavoie, E. J., and Rice, J. E. (2008) Biochimie 90, 1233-1249
16. Barbieri, C. M., Srinivasan, A. R., Rzuczek, S. G., Rice, J. E., LaVoie, E. J., and Pilch, D. S. (2007) Nucleic Acids Res. 35, 3272-3286
17. Kim, M. Y., Vankayalapati, H., Shin-Ya, K., Wierzba, K., and Hurley, L. H. (2002) J. Am. Chem. Soc. 124, 2098-2099
18. Binz, N., Shalaby, T., Rivera, P., Shin-ya, K., and Grotzer, M. A. (2005) Eur. J. Cancer 41, 2873-2881
19. Doi, T., Yoshida, M., Shin-ya, K., and Takahashi, T. (2006) Org. Lett. 8, 4165-4167
20. Minhas, G. S., Pilch, D. S., Kerrigan, J. E., LaVoie, E. J., and Rice, J. E. (2006) Bioorg. Med. Chem. Lett. 16, 3891-3895
21. Satyanarayana, M., Rzuczek, S. G., Lavoie, E. J., Pilch, D. S., Liu, A., Liu, L. F., and Rice, J. E. (2008) Bioorg. Med. Chem. Lett. 18, 3802-3804
22. Rzuczek, S. G., Pilch, D. S., LaVoie, E. J., and Rice, J. E. (2008) Bioorg. Med. Chem. Lett. 18, 913-917
23. Qi, H., Lin, C. P., Fu, X., Wood, L. M., Liu, A. A., Tsai, Y. C., Chen, Y., Barbieri, C. M., Pilch, D. S., and Liu, L. F. (2006) Cancer Res. 66, 11808-11816
24. Cimino-Reale, G., Pascale, E., Battiloro, E., Starace, G., Verna, R., and D'Ambrosio, E. (2001) Nucleic Acids Res. 29, E35
25. Bryan, T. M., Marusic, L., Bacchetti, S., Namba, M., and Reddel, R. R. (1997) Hum. Mol. Genet. 6, 921-926
26. Londoño-Vallejo, J. A., Der-Sarkissian, H., Cazes, L., Bacchetti, S., and Reddel, R. R. (2004) Cancer Res. 64, 2324-2327
27. Perrem, K., Colgin, L. M., Neumann, A. A., Yeager, T. R., and Reddel, R. R. (2001) Mol. Cell. Biol. 21, 3862-3875
28. Hayflick, L., and Moorhead, P. S. (1961) Exp. Cell Res. 25, 585-621
29. Karlseder, J., Broccoli, D., Dai, Y., Hardy, S., and de Lange, T. (1999) Science 283, 1321-1325
30. Li, T. K., and Liu, L. F. (2001) Annu. Rev. Pharmacol. Toxicol. 41, 53-77
31. O'Loughlin, C., Heenan, M., Coyle, S., and Clynes, M. (2000) Eur. J. Cancer 36, 1149-1160
32. Parrish, J. Z., and Xue, D. (2006) Chromosoma 115, 89-97
33. Goto, H., Tomono, Y., Ajiro, K., Kosako, H., Fujita, M., Sakurai, M., Okawa, K., Iwamatsu, A., Okigaki, T., Takahashi, T., and Inagaki, M. (1999) J. Biol. Chem. 274, 25543-25549
34. Hoffmann, I., and Karsenti, E. (1994) J. Cell Sci. Suppl. 18, 75-79
35. Carmena, M., and Earnshaw, W. C. (2003) Nat. Rev. Mol. Cell Biol. 4, 842-854
36. Kunitoku, N., Sasayama, T., Marumoto, T., Zhang, D., Honda, S., Kobayashi, O., Hatakeyama, K., Ushio, Y., Saya, H., and Hirota, T. (2003) Dev. Cell 5, 853-864
37. Taguchi, S., Honda, K., Sugiura, K., Yamaguchi, A., Furukawa, K., and Urano, T. (2002) FEBS Lett. 519, 59-65
38. Walter, A. O., Seghezzi, W., Korver, W., Sheung, J., and Lees, E. (2000) Oncogene 19, 4906-4916
39. Mikami-Terao, Y., Akiyama, M., Yuza, Y., Yanagisawa, T., Yamada, O., and Yamada, H. (2008) Cancer Lett. 261, 226-234
40. Kim, M. Y., Gleason-Guzman, M., Izbicka, E., Nishioka, D., and Hurley, L. H. (2003) Cancer Res. 63, 3247-3256
41. Artandi, S. E., and DePinho, R. A. (2000) Curr. Opin. Genet. Dev. 10, 39-46
42. Pardue, M. L., and DeBaryshe, P. G. (2003) Annu. Rev. Genet. 37, 485-511
43. Hars, E. S., Lyu, Y. L., Lin, C. P., and Liu, L. F. (2006) Cancer Res. 66, 8975-8979
44. Ausió, J. (2006) Brief. Funct. Genomics Proteomics 5, 228-243
45. Heit, R., Underhill, D. A., Chan, G., and Hendzel, M. J. (2006) Biochem. Cell Biol. 84, 605-618
46. Ke, Y. W., Dou, Z., Zhang, J., and Yao, X. B. (2003) Cell Res. 13, 69-81
47. Li, J. J., Weroha, S. J., Lingle, W. L., Papa, D., Salisbury, J. L., and Li, S. A. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 18123-18128
48. Evans, R., Naber, C., Steffler, T., Checkland, T., Keats, J., Maxwell, C., Perry, T., Chau, H., Belch, A., Pilarski, L., and Reiman, T. (2008) Leuk Lymphoma 49, 559-569
49. Kumari, S., Bugaut, A., Huppert, J. L., and Balasubramanian, S. (2007) Nat. Chem. Biol. 3, 218-221
50. Saccà, B., Lacroix, L., and Mergny, J. L. (2005) Nucleic Acids Res. 33, 1182-1192
51. Horn, V., Thélu, J., Garcia, A., Albigès-Rizo, C., Block, M. R., and Viallet, J. (2007) Mol. Biol. Cell 18, 1233-1241
52. Huppert, J. L., Bugaut, A., Kumari, S., and Balasubramanian, S. (2008) Nucleic Acids Res. 36, 6260-6268