Lysinyl macrocyclic hexaoxazoles: Synthesis and selective G-quadruplex stabilizing properties

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 913-917

  Rzuczek, Suzanne G ^a   Pilch, Daniel S ^b,c   LaVoie, Edmond J ^a,c   Rice, Joseph E ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

G quadruplex stabilizers; Lysine; Macrocyclic hexaoxazoles; Selective; Synthesis

Indexed keywords

ACETAMIDE; AMINE; DOUBLE STRANDED DNA; HEXAOXAZOLE; LYSINE; LYSINYL MACROCYCLIC HEXAOXAZOLE; N,N DIMETHYLAMINE; NITROGEN; OXAZOLE DERIVATIVE; POLYOXAZOLE; SODIUM ION; UNCLASSIFIED DRUG; VALINE;

ARTICLE; CYCLIZATION; DRUG SELECTIVITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; GUANINE QUADRUPLEX;

DNA; DRUG DESIGN; G-QUADRUPLEXES; LYSINE; MACROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE; OXAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38749119006     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.048     Document Type: Article

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