Useful synthesis of the longer array oxazole rings for telomestatin

Heterocycles

Volumn 60, Issue 7, 2003, Pages 1567-1572

  Endoh, Nobuaki ^a   Tsuboi, Katumasa ^a   Kim, Riyong ^a   Yonezawa, Yasuchika ^a   Shin, Chung gi ^a  

^a KANAGAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

OXAZOLE; TELOMESTATIN; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CYCLIZATION; DRUG SYNTHESIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY;

EID: 0037588850     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-03-9783     Document Type: Article

References (21)

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10. In this paper, the symbol Δ2 indicates the position number of double bond of α-dehydroamino acid residue from the N-terminus in sequence.
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14. 2), 5.25(dd, 1H, J=2.0, 6.3 Hz, α-H), 7.09-7.38 (m, 5H, Cbz's Ph), 8.77 (s, 1H, ring-H).
15. 2), 6.97-7.35 (m, 5H, Cbz' Ph), 8.67 (s, 1 × 2/3 H, ring-H), 8.85 (s, 1 × 1/3 H, ring-H).
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17. BOP: Benzyltriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate.
18. 8Si: C, 66.12; H, 6.08; N, 7.34. Found: C, 65.88; H, 5.98; N, 7.73.
19. 8: C, 58.30; H, 4.48; N, 11.33. Found: C, 58.21; H, 4.46; N, 11.50
20. 13Si: C, 63.09; H, 4.83; N, 10.33. Found: C, 63.12; H, 4.92; N, 10.17.
21. +.