A phenol quaternary ammonium porphyrin as a potent telomerase inhibitor by selective interaction with quadruplex DNA

ChemBioChem

Volumn 7, Issue 8, 2006, Pages 1155-1159

  Wang, Ping ^a   Ren, Lige ^a   He, Hanping ^a   Liang, Feng ^a   Zhou, Xiang ^a   Tan, Zheng ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

G quadruplexes; Inhibitors; Phenol; Porphyrins; Quaternary ammonium; Telomerases

Indexed keywords

5,10,15,20 TETRA[4 HYDROXY 3 (TRIMETHYLAMMONIUM)METHYLPHENYL]PORPHYRIN; 5,10,15,20 TETRAKIS(N METHYL 4 PYRIDYL) 21H,23H PORPHYRIN; AMMONIA; DNA; DNA POLYMERASE; DOUBLE STRANDED DNA; GUANINE DERIVATIVE; PHENOL; PORPHYRIN; PORPHYRIN DERIVATIVE; QUINONE DERIVATIVE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOSENSOR; CIRCULAR DICHROISM; DNA CROSS LINKING; DRUG INHIBITION; DRUG SYNTHESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; ULTRAVIOLET RADIATION;

DNA; ENZYME INHIBITORS; MOLECULAR CONFORMATION; PHENOL; PORPHYRINS; SURFACE PLASMON RESONANCE; TAQ POLYMERASE; TELOMERASE;

EID: 33747168762     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200600036     Document Type: Article

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