Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure

Journal of the American Chemical Society

Volumn 127, Issue 26, 2005, Pages 9439-9447

  Rezler, Evonne M ^a   Seenisamy, Jeyaprakashnarayanan ^a   Bashyam, Sridevi ^a   Kim, Mu Yong ^a   White, Elizabeth ^b   Wilson, W David ^b   Hurley, Laurence H ^a,c,d  

^a UNIVERSITY OF ARIZONA   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOSENSORS; ENZYMES; NUCLEIC ACIDS; OLIGOMERS; STOICHIOMETRY; SURFACE PLASMON RESONANCE;

INCUBATION; OLIGONUCLEOTIDES; TELOMERIC SEQUENCES; TELOMESTATIN;

COPOLYMERS;

5,10,15,20 TETRAKIS(N METHYL 3 PYRIDYL) 26,28 DISELENASAPPHYRIN CHLORIDE; CATION; DNA BINDING PROTEIN; NATURAL PRODUCT; PORPHYRIN DERIVATIVE; POTASSIUM ION; SINGLE STRANDED DNA; SODIUM ION; TAQ POLYMERASE; TELOMERASE INHIBITOR; TELOMESTATIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; DNA PROTEIN COMPLEX; DNA SEQUENCE; DRUG ISOLATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; STOICHIOMETRY; STREPTOMYCES; STREPTOMYCES ANULATUS; SURFACE PLASMON RESONANCE; TELOMERE; TETRAHYMENA;

BINDING SITES; CIRCULAR DICHROISM; DNA; HUMANS; LIGANDS; MOLECULAR STRUCTURE; OLIGONUCLEOTIDES; ONCOGENE PROTEINS; OXAZOLES; POLYMERASE CHAIN REACTION; PORPHYRINS; POTASSIUM; SELENIUM COMPOUNDS; SODIUM; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE; TELOMERE;

EID: 21644460419     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0505088     Document Type: Article

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