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13
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33748931507
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note
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PyBroP = bromo-trispyrrolidino-phosphonium hexafluorophosphate.
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14
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16
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33748925268
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note
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Several condensation reagents were investigated using the corresponding S-trityl derivative: PyBrop, 90%; HATU-HOAt, 78%; PyBop-HOBt, 69%; EDCI-HOBT, 53%.
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17
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24
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33748926995
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note
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Chattopadhyay et al. recently reported the synthesis of its methyl ester. See ref 5e.
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25
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0015520853
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DPPA = diphenyl phosphorazidate. Shioiri, T.; Ninomiya, K.; Yamada, S. J. Am. Chem. Soc. 1972, 94, 6203-6205.
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Shioiri, T.1
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Yamada, S.3
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26
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33748919704
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note
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In the absence of MS4A, the sulfide moiety was partially oxidized. The S-trityl derivative was decomposed under these reaction conditions.
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27
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33748924023
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note
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3 is usually selected for an oxazoline formation. However, the elimination of thiol was observed in this system.
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28
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33748926319
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note
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In the absence of MS5A, ring opening of the oxazoline by hydrolysis was observed.
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29
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0037414956
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You, S.; Razavi, H.; Kelly, J. W. Angew. Chem., Int. Ed. 2003, 42, 83-85.
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You, S.1
Razavi, H.2
Kelly, J.W.3
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30
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33748948805
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note
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Without addition of anisole, the reaction was not complete.
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