Quadruplex-interactive agents as telomerase inhibitors: Synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase

Journal of Medicinal Chemistry

Volumn 44, Issue 26, 2001, Pages 4509-4523

  Shi, D F ^a   Wheelhouse, R T ^a,b   Sun, D ^c   Hurley, L H ^a,d,e  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

^c CTRC Institute for Drug Development   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

^e UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,10,15,20 TETRAKIS(N METHYL 4 PYRIDYL)PORPHYRIN CHLORIDE; 5,10,15,20 TETRAKIS[5 (2 FURFURYL) N METHYL 3 PYRIDYL]PORPHYRIN CHLORIDE; DNA; PORPHYRIN DERIVATIVE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; TELOMERE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL-FREE SYSTEM; DNA; ENZYME INHIBITORS; HELA CELLS; HUMANS; MODELS, MOLECULAR; PORPHYRINS; PYRIDINES; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP; TELOMERASE;

EID: 0035924232     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010246u     Document Type: Article

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