Epileptogenic ion channel mutations: From bedside to bench and, hopefully, back again

Epilepsy Research

Volumn 92, Issue 1, 2010, Pages 1-29

  Mantegazza, Massimo ^a,b   Rusconi, Raffaella ^a,b   Scalmani, Paolo ^b   Avanzini, Giuliano ^b   Franceschetti, Silvana ^b  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

Channelopathies; Epilepsy; Excitability; Genetics; Ion currents; Seizures

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA3; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM CHANNEL T TYPE; CHLORIDE CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR4.1; ION CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NICOTINIC RECEPTOR ALPHA4; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ3; POTASSIUM CHANNEL KV1.1; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.3; SODIUM CHANNEL NAV1.7; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

BRAIN SLICE; CHANNELOPATHY; CLINICAL PRACTICE; COMPUTER MODEL; DISEASE MODEL; EPILEPSY; EPILEPTOGENESIS; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE MUTATION; GENE TARGETING; GENETIC LINKAGE; GENETIC VARIABILITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INHERITANCE; MAMMAL CELL; NERVE CELL CULTURE; NONHUMAN; OOCYTE; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; TRANSGENIC ANIMAL; XENOPUS;

ANIMALS; CHANNELOPATHIES; DISEASE MODELS, ANIMAL; EPILEPSY; HUMANS; ION CHANNELS; MUTATION;

EID: 77957887806     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2010.08.003     Document Type: Review

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