Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

Nature Neuroscience

Volumn 9, Issue 9, 2006, Pages 1142-1149

  Yu, Frank H ^a   Mantegazza, Massimo ^a,c   Westenbroek, Ruth E ^a   Robbins, Carol A ^a,b   Kalume, Franck ^a   Burton, Kimberly A ^a   Spain, William J ^b   McKnight, G Stanley ^a   Scheuer, Todd ^a   Catterall, William A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; SODIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; BRAIN NERVE CELL; DEATH; DISEASE MODEL; DISEASE SEVERITY; FEEDING; HETEROZYGOTE; HIPPOCAMPUS; HOMOZYGOTE; IMMUNOCYTOCHEMISTRY; INTERNEURON; KNOCKOUT MOUSE; MOUSE; MUTATION; MYOCLONUS EPILEPSY; NONHUMAN; PERINATAL DEATH; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SEIZURE; SODIUM CURRENT; UPREGULATION;

ACTION POTENTIALS; ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EPILEPSIES, MYOCLONIC; GAMMA-AMINOBUTYRIC ACID; GENOTYPE; HUMANS; IMMUNOBLOTTING; INFANT; INTERNEURONS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MUTATION; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PHENOTYPE; SEIZURES; SODIUM CHANNELS; SURVIVAL RATE;

EID: 33748115786     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1754     Document Type: Article

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