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Volumn 588, Issue 11, 2010, Pages 1849-1859

NaV1.1 channels and epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; MESSENGER RNA; SODIUM CHANNEL BLOCKING AGENT; VACCINE; VOLTAGE GATED SODIUM CHANNEL;

EID: 77954529023     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.187484     Document Type: Review
Times cited : (339)

References (78)
  • 3
    • 0024810594 scopus 로고
    • Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development
    • Beckh S, Noda M, Lübbert H, Numa S. Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development. EMBO J 1989, 8:3611-3616.
    • (1989) EMBO J , vol.8 , pp. 3611-3616
    • Beckh, S.1    Noda, M.2    Lübbert, H.3    Numa, S.4
  • 5
    • 62549109964 scopus 로고    scopus 로고
    • Cation-chloride cotransporters and neuronal function
    • Blaesse P, Airaksinen MS, Rivera C, Kaila K. Cation-chloride cotransporters and neuronal function. Neuron 2009, 61:820-838.
    • (2009) Neuron , vol.61 , pp. 820-838
    • Blaesse, P.1    Airaksinen, M.S.2    Rivera, C.3    Kaila, K.4
  • 7
    • 0031029564 scopus 로고    scopus 로고
    • Spatial distribution of synaptically activated sodium concentration changes in cerebellar Purkinje neurons
    • Callaway JC, Ross WN. Spatial distribution of synaptically activated sodium concentration changes in cerebellar Purkinje neurons. J Neurophysiol 1997, 77:145-152.
    • (1997) J Neurophysiol , vol.77 , pp. 145-152
    • Callaway, J.C.1    Ross, W.N.2
  • 8
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • Catterall WA. From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels. Neuron 2000, 26:13-25.
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catterall, W.A.1
  • 9
    • 58149326824 scopus 로고    scopus 로고
    • Inherited neuronal ion channelopathies: new windows on complex neurological diseases
    • Catterall WA, Dib-Hajj S, Meisler MH, Pietrobon D. Inherited neuronal ion channelopathies: new windows on complex neurological diseases. J Neurosci 2008, 28:11768-11777.
    • (2008) J Neurosci , vol.28 , pp. 11768-11777
    • Catterall, W.A.1    Dib-Hajj, S.2    Meisler, M.H.3    Pietrobon, D.4
  • 13
    • 12244289247 scopus 로고    scopus 로고
    • Functional characterization of the D188V mutation in neuronal voltage-gated sodium channel causing generalized epilepsy with febrile seizures plus (GEFS)
    • Cossette P, Loukas A, Lafreniere RG, Rochefort D, Harvey-Girard E, Ragsdale DS, Dunn RJ, Rouleau GA. Functional characterization of the D188V mutation in neuronal voltage-gated sodium channel causing generalized epilepsy with febrile seizures plus (GEFS). Epilepsy Res 2003, 53:107-117.
    • (2003) Epilepsy Res , vol.53 , pp. 107-117
    • Cossette, P.1    Loukas, A.2    Lafreniere, R.G.3    Rochefort, D.4    Harvey-Girard, E.5    Ragsdale, D.S.6    Dunn, R.J.7    Rouleau, G.A.8
  • 17
    • 0034957202 scopus 로고    scopus 로고
    • A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology
    • Engel J. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. Epilepsia 2001, 42:796-803.
    • (2001) Epilepsia , vol.42 , pp. 796-803
    • Engel, J.1
  • 22
    • 74449088183 scopus 로고    scopus 로고
    • Differential expression of exon 5 splice variants of sodium channel α subunit mRNAs in the developing mouse brain
    • Gazina EV, Richards KL, Mokhtar MB, Thomas EA, Reid CA, Petrou S. Differential expression of exon 5 splice variants of sodium channel α subunit mRNAs in the developing mouse brain. Neuroscience 2009, 166:195-200.
    • (2009) Neuroscience , vol.166 , pp. 195-200
    • Gazina, E.V.1    Richards, K.L.2    Mokhtar, M.B.3    Thomas, E.A.4    Reid, C.A.5    Petrou, S.6
  • 23
    • 0035050571 scopus 로고    scopus 로고
    • Resurgence of sodium channel research
    • Goldin AL. Resurgence of sodium channel research. Annu Rev Physiol 2001, 63:871-894.
    • (2001) Annu Rev Physiol , vol.63 , pp. 871-894
    • Goldin, A.L.1
  • 26
    • 0035155962 scopus 로고    scopus 로고
    • Mutant mice as a model for cerebellar ataxia
    • Grusser-Cornehls U, Baurle J. Mutant mice as a model for cerebellar ataxia. Prog Neurobiol 2001, 63:489-540.
    • (2001) Prog Neurobiol , vol.63 , pp. 489-540
    • Grusser-Cornehls, U.1    Baurle, J.2
  • 29
    • 0036369748 scopus 로고    scopus 로고
    • The role of sodium channels in cell adhesion
    • Isom LL. The role of sodium channels in cell adhesion. Front Biosci 2002, 7:12-23.
    • (2002) Front Biosci , vol.7 , pp. 12-23
    • Isom, L.L.1
  • 30
    • 0028972374 scopus 로고
    • Structure and function of the beta-2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM-motif
    • Isom LL, Ragsdale DS, De Jongh KS, Westenbroek RE, Reber BFX, Scheuer T, Catterall WA. Structure and function of the beta-2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM-motif. Cell 1995, 83:433-442.
    • (1995) Cell , vol.83 , pp. 433-442
    • Isom, L.L.1    Ragsdale, D.S.2    De Jongh, K.S.3    Westenbroek, R.E.4    Reber, B.F.X.5    Scheuer, T.6    Catterall, W.A.7
  • 31
    • 0035956420 scopus 로고    scopus 로고
    • Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments
    • Jenkins SM, Bennett V. Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments. J Cell Biol 2001, 155:739-746.
    • (2001) J Cell Biol , vol.155 , pp. 739-746
    • Jenkins, S.M.1    Bennett, V.2
  • 33
    • 33751108977 scopus 로고    scopus 로고
    • Impaired inactivation gate stabilization predicts increased persistent current for an epilepsy-associated SCN1A mutation
    • Kahlig KM, Misra SN, George AL. Impaired inactivation gate stabilization predicts increased persistent current for an epilepsy-associated SCN1A mutation. J Neurosci 2006, 26:10958-10966.
    • (2006) J Neurosci , vol.26 , pp. 10958-10966
    • Kahlig, K.M.1    Misra, S.N.2    George, A.L.3
  • 34
    • 35348904490 scopus 로고    scopus 로고
    • Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy
    • Kalume F, Yu FH, Westenbroek RE, Scheuer T, Catterall WA. Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy. J Neurosci 2007, 27:11065-11074.
    • (2007) J Neurosci , vol.27 , pp. 11065-11074
    • Kalume, F.1    Yu, F.H.2    Westenbroek, R.E.3    Scheuer, T.4    Catterall, W.A.5
  • 36
    • 33644526324 scopus 로고    scopus 로고
    • Relative contributions of axonal and somatic Na channels to action potential initiation in cerebellar Purkinje neurons
    • Khaliq ZM, Raman IM. Relative contributions of axonal and somatic Na channels to action potential initiation in cerebellar Purkinje neurons. J Neurosci 2006, 26:1935-1944.
    • (2006) J Neurosci , vol.26 , pp. 1935-1944
    • Khaliq, Z.M.1    Raman, I.M.2
  • 38
    • 65049088044 scopus 로고    scopus 로고
    • Preclinical assessment of proconvulsant drug activity and its relevance for predicting adverse events in humans
    • Loscher W. Preclinical assessment of proconvulsant drug activity and its relevance for predicting adverse events in humans. Eur J Pharmacol 2009, 610:1-11.
    • (2009) Eur J Pharmacol , vol.610 , pp. 1-11
    • Loscher, W.1
  • 43
    • 35848965669 scopus 로고    scopus 로고
    • The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy
    • Martin MS, Tang B, Papale LA, Yu FH, Catterall WA, Escayg A. The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy. Hum Mol Genet 2007, 16:2892-2899.
    • (2007) Hum Mol Genet , vol.16 , pp. 2892-2899
    • Martin, M.S.1    Tang, B.2    Papale, L.A.3    Yu, F.H.4    Catterall, W.A.5    Escayg, A.6
  • 45
    • 23644439941 scopus 로고    scopus 로고
    • Sodium channel mutations in epilepsy and other neurological disorders
    • Meisler MH, Kearney JA. Sodium channel mutations in epilepsy and other neurological disorders. J Clin Invest 2005, 115:2010-2017.
    • (2005) J Clin Invest , vol.115 , pp. 2010-2017
    • Meisler, M.H.1    Kearney, J.A.2
  • 47
    • 62649142705 scopus 로고    scopus 로고
    • Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy
    • Oakley JC, Kalume F, Yu FH, Scheuer T, Catterall WA. Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy. Proc Natl Acad Sci U S A 2009, 106:3994-3999.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3994-3999
    • Oakley, J.C.1    Kalume, F.2    Yu, F.H.3    Scheuer, T.4    Catterall, W.A.5
  • 49
    • 0034778243 scopus 로고    scopus 로고
    • Severe myoclonic epilepsy in infants: a review based on the Tokyo Women's Medical University series of 84 cases
    • Oguni H, Hayashi K, Awaya Y, Fukuyama Y, Osawa M. Severe myoclonic epilepsy in infants: a review based on the Tokyo Women's Medical University series of 84 cases. Brain Dev 2001, 23:736-748.
    • (2001) Brain Dev , vol.23 , pp. 736-748
    • Oguni, H.1    Hayashi, K.2    Awaya, Y.3    Fukuyama, Y.4    Osawa, M.5
  • 51
    • 0036304363 scopus 로고    scopus 로고
    • Significant correlation of the SCN1A mutations and severe myoclonic epilepsy in infancy
    • Ohmori I, Ouchida M, Ohtsuka Y, Oka E, Shimizu K. Significant correlation of the SCN1A mutations and severe myoclonic epilepsy in infancy. Biochem Biophys Res Commun 2002, 295:17-23.
    • (2002) Biochem Biophys Res Commun , vol.295 , pp. 17-23
    • Ohmori, I.1    Ouchida, M.2    Ohtsuka, Y.3    Oka, E.4    Shimizu, K.5
  • 54
    • 45649085478 scopus 로고    scopus 로고
    • How do mutant Nav1.1 sodium channels cause epilepsy?
    • Ragsdale DS. How do mutant Nav1.1 sodium channels cause epilepsy?. Brain Res Rev 2008, 58:149-159.
    • (2008) Brain Res Rev , vol.58 , pp. 149-159
    • Ragsdale, D.S.1
  • 55
    • 0031010957 scopus 로고    scopus 로고
    • Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons
    • Raman IM, Bean BP. Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. J Neurosci 1997, 17:4517-4526.
    • (1997) J Neurosci , vol.17 , pp. 4517-4526
    • Raman, I.M.1    Bean, B.P.2
  • 56
    • 0033103324 scopus 로고    scopus 로고
    • Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons
    • Raman IM, Bean BP. Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons. J Neurosci 1999a, 19:1664-1674.
    • (1999) J Neurosci , vol.19 , pp. 1664-1674
    • Raman, I.M.1    Bean, B.P.2
  • 57
    • 0032968941 scopus 로고    scopus 로고
    • Properties of sodium currents and action potential firing in isolated cerebellar Purkinje neurons
    • Raman IM, Bean BP. Properties of sodium currents and action potential firing in isolated cerebellar Purkinje neurons. Ann N Y Acad Sci 1999b, 868:93-96.
    • (1999) Ann N Y Acad Sci , vol.868 , pp. 93-96
    • Raman, I.M.1    Bean, B.P.2
  • 59
    • 67649656143 scopus 로고    scopus 로고
    • A rescuable folding defective Nav1.1 (SCN1A) sodium channel mutant causes GEFS+: common mechanism in Nav1.1 related epilepsies?
    • Rusconi R, Combi R, Cestele S, Grioni D, Franceschetti S, Dalpra L, Mantegazza M. A rescuable folding defective Nav1.1 (SCN1A) sodium channel mutant causes GEFS+: common mechanism in Nav1.1 related epilepsies?. Hum Mutat 2009, 30:E747-760.
    • (2009) Hum Mutat , vol.30
    • Rusconi, R.1    Combi, R.2    Cestele, S.3    Grioni, D.4    Franceschetti, S.5    Dalpra, L.6    Mantegazza, M.7
  • 61
    • 0026055009 scopus 로고
    • Developmentally regulated alternative RNA splicing of rat brain sodium channel mRNAs
    • Sarao R, Gupta SK, Auld VJ, Dunn RJ. Developmentally regulated alternative RNA splicing of rat brain sodium channel mRNAs. Nucleic Acids Res 1991, 19:5673-5679.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5673-5679
    • Sarao, R.1    Gupta, S.K.2    Auld, V.J.3    Dunn, R.J.4
  • 63
    • 64449088896 scopus 로고    scopus 로고
    • Dravet syndrome or genetic (generalized) epilepsy with febrile seizures plus?
    • Scheffer IE, Zhang YH, Jansen FE, Dibbens L. Dravet syndrome or genetic (generalized) epilepsy with febrile seizures plus?. Brain Dev 2009, 31:394-400.
    • (2009) Brain Dev , vol.31 , pp. 394-400
    • Scheffer, I.E.1    Zhang, Y.H.2    Jansen, F.E.3    Dibbens, L.4
  • 65
    • 0035478007 scopus 로고    scopus 로고
    • Functional effects of two voltage-gated sodium channel mutations that cause generalized epilepsy with febrile seizures plus type 2
    • Spampanato J, Escayg A, Meisler MH, Goldin AL. Functional effects of two voltage-gated sodium channel mutations that cause generalized epilepsy with febrile seizures plus type 2. J Neurosci 2001, 21:7481-7490.
    • (2001) J Neurosci , vol.21 , pp. 7481-7490
    • Spampanato, J.1    Escayg, A.2    Meisler, M.H.3    Goldin, A.L.4
  • 66
    • 0346106074 scopus 로고    scopus 로고
    • Generalized epilepsy with febrile seizures plus type 2 mutation W1204R alters voltage-dependent gating of Nav1.1 sodium channels
    • Spampanato J, Escayg A, Meisler MH, Goldin AL. Generalized epilepsy with febrile seizures plus type 2 mutation W1204R alters voltage-dependent gating of Nav1.1 sodium channels. Neuroscience 2003, 116:37-48.
    • (2003) Neuroscience , vol.116 , pp. 37-48
    • Spampanato, J.1    Escayg, A.2    Meisler, M.H.3    Goldin, A.L.4
  • 68
    • 0028058194 scopus 로고
    • Active propagation of somatic action potentials into neocortical pyramidal cell dendrites
    • Stuart GJ, Sakmann B. Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature 1994, 367:69-72.
    • (1994) Nature , vol.367 , pp. 69-72
    • Stuart, G.J.1    Sakmann, B.2
  • 73
    • 2342527262 scopus 로고    scopus 로고
    • Localization of voltage-gated ion channels in mammalian brain
    • Trimmer JS, Rhodes KJ. Localization of voltage-gated ion channels in mammalian brain. Annu Rev Physiol 2004, 66:477-519.
    • (2004) Annu Rev Physiol , vol.66 , pp. 477-519
    • Trimmer, J.S.1    Rhodes, K.J.2
  • 74
    • 29844445037 scopus 로고    scopus 로고
    • Single-channel properties of human Nav1.1 and mechanism of channel dysfunction in SCN1A-associated epilepsy
    • Vanoye CG, Lossin C, Rhodes TH, George AL. Single-channel properties of human Nav1.1 and mechanism of channel dysfunction in SCN1A-associated epilepsy. J Gen Physiol 2006, 127:1-14.
    • (2006) J Gen Physiol , vol.127 , pp. 1-14
    • Vanoye, C.G.1    Lossin, C.2    Rhodes, T.H.3    George, A.L.4
  • 76
    • 0024797279 scopus 로고
    • Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons
    • Westenbroek RE, Merrick DK, Catterall WA. Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons. Neuron 1989, 3:695-704.
    • (1989) Neuron , vol.3 , pp. 695-704
    • Westenbroek, R.E.1    Merrick, D.K.2    Catterall, W.A.3
  • 77
    • 0026763362 scopus 로고
    • Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain
    • Westenbroek RE, Noebels JL, Catterall WA. Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain. J Neurosci 1992, 12:2259-2267.
    • (1992) J Neurosci , vol.12 , pp. 2259-2267
    • Westenbroek, R.E.1    Noebels, J.L.2    Catterall, W.A.3


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