Developmental seizure susceptibility of Kv1.1 potassium channel knockout mice

Developmental Neuroscience

Volumn 21, Issue 3-5, 1999, Pages 320-327

  Rho, Jong M ^a,c   Szot, Patricia ^b   Tempel, Bruce L ^a   Schwartzkroin, Philip A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

Author keywords

c fos; Development; Epilepsy; Flurothyl; Hippocampus; Kv1.1 potassium channel; Neocortex

Indexed keywords

MESSENGER RNA; POTASSIUM CHANNEL; PROTEIN SUBUNIT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA; DISEASE PREDISPOSITION; EPILEPSY; GENE LOCUS; GENE MUTATION; GENOTYPE; IMMEDIATE EARLY GENE; KNOCKOUT MOUSE; MOUSE; MYOKYMIA; NERVE STIMULATION; NEWBORN; NONHUMAN; ONCOGENE C FOS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; SEIZURE SUSCEPTIBILITY;

EID: 0032713742     PISSN: 03785866     EISSN: None     Source Type: Journal    
DOI: 10.1159/000017381     Document Type: Article

References (41)

1. Baumann A, Grupe A, Ackermann A, Pongs O (1988): Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous systems. EMBO J 7:2457-2463.
2. Biervert C, Schroeder BC, Kubisch C, Berkovic SF, Propping P, Jentsch TJ, Steinlein OK (1998): A potassium channel mutation in neonatal human epilepsy. Science 279:403-406.
3. Bosma MM, Allen ML, Martin TM, Tempel BL (1993): PKA-dependent regulation of mKv 1.1, a mouse Shaker-like potassium channel gene, when stably expressed in CHO cells. J Neurosci 13:5242-5250.
4. van Brederode JFM, Rho JM, Cerne R, Tempel BL, Spain W (1998): Evidence of altered inhibition of layer V pyramidal neurons from neocortex of Kv1.1 potassium channel knockout mice. Soc Neurosci Abstr 24:1213.
5. Browne DL, Gancher ST, Nutt JG, Brunt ERP, Smith EA, Kramer P, Litt M (1994): Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNAI. Nat Genet 8:136-140.
6. Chandy KG, Gutman GA (1993): Nomenclature for mammalian potassium channel genes. Trends Pharmacol Sci 14:434.
7. Chandy KG, Williams CB. Spencer RH, Aguilar BA, Ghanshani S, Tempel BL, Gutman GA (1990): A family of three mouse potassium channel genes with intronless coding regions. Science 247:973-975.
8. Charlier C, Singh NA, Ryan SG, Lewis TB, Reos BE, Leach RJ, Leppert M (1998): A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family. Nat Genet 18:53-55.
9. Clark JD, Tempel BL (1998): Hyperalgesia in mice lacking the Kv1.1 potassium channel gene. Neurosci Lett 251:121-124.
10. Dragunow M, Robertson HA (1987): Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus. Nature 329:441-442.
11. Dragunow M, Robertson HA (1988): Localization and induction of c-fos protein-like immunoreactive material in the nuclei of adult mammalian neurons. Brain Res 440:252-260.
12. Franklin KBJ, Paxinos G (1997): The Mouse Brain in Stereotaxic Coordinates. New York, Academic Press.
13. Hille B (1992): Ionic Channels of Excitable Membranes. Sunderland, Sinauer.
14. Kamb A, Tseng CJ, Tanouye MA (1988): Multiple products of the Drosophila Shaker gene may contribute to potassium channel diversity. Neuron 1:421-430.
15. Mello LE, Kohman CM, Tan AM, Cavalheiro EA, Finch DM (1996): Lack of fos-like immunoreactivity after spontaneous seizures or reinduction of status epilepticus by pilocarpine in rats. Neurosci Lett 208:133-137.
16. Morgan JI, Cohen DR, Hempstead JL, Curran T (1987): Mapping patterns of c-fos expression in the central nervous system after seizure. Science 237:192-197.
17. Morgan JI, Curran T (1991): Proto-oncogene transcription factors and epilepsy. Trends Pharmacol Sci 12:343-349.
18. Moshé SL, Albala BJ, Ackermann RF, Engel J Jr (1983): Increased seizure susceptibility of the immature brain. Brain Res 7:81-85.
19. Moshé SL, Velišek L, Holmes GL (1994): Developmental aspects of experimental generalized seizures induced by pentylenetetrazol, bicuculline and flurothyl; in Malafosse A, Genton P, Hirsch E, Marescaux C, Broglin D, Bernasconi R (eds): Idiopathic Generalized Epilepsies: Clinical, Experimental and Genetic Aspects. London, Libbey & Sons, pp 51-64.
20. Motte JE, da Silva Fernandes MJ, Marescaux C, Nehlig A (1997): Effects of pentylenetetrazol-induced status epilepticus on c-Fos and HSP-72 immunoreactivity in the immature rat brain. Mol Brain Res 50:79-84.
21. Murashima YL, Kasamo K, Suzuki J (1996): Developmental and seizure-related regional differences in immediate early gene expression and GABAergic abnormalities in the brain of EL mice. Epilepsy Res 26:3-14.
22. Papazian DM, Schwarz TL, Tempel BL, Jan YN, Jan LY (1987): Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science 237:749-753.
23. Pongs O, Kecskemethy N, Muller R, Krah-Jentgens I, Baumann A, Kiltz HH, Canal I, Llamazares S, Ferrus A (1988): Shaker encodes a family of putative potassium channel proteins in the nervous system of Drosophila. EMBO J 7:1087-1096.
24. Prichard JW, Gallagher BB, Glaser GH (1969): Experimental seizure-threshold testing with flurothyl. J Pharmacol Exp Ther 166:170-178.
25. + channel genotype influences susceptibility to kainate-induced seizures in immature mice. Epilepsia 39(suppl 6):27.
26. + channels. Neuroscience 25:729-749.
27. + channel components from the Shaker locus and differential distribution of splicing variants in Drosophila. Neuron 4:119-127.
28. Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY (1988): Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature 331:137-142.
29. Sheng M, Greenberg ME (1990): The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 4:477-485.
30. Singh NA, Charlier C, Stauffer D, DuPont BR, Leach RJ, Melis R, Ronen GM, Bjerre I, Quattlebaum T, Murphy JV, McHarg ML, Gagnon D, Rosales TO, Peiffer A, Anderson VE, Leppert M (1998): A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns. Nat Genet 18:25-29.
31. Smart SL, Lopantsev V, Zhang CL, Robbins CA, Wang H, Chiu SY, Schwartzkroin PA, Messing A, Tempel BL (1998): Deletion of the Kv1.1 potassium channel causes epilepsy in mice. Neuron 20:809-819.
32. Sonnenberg JL, Mitchelmore C, McGregor-Leon PF, Hempstead J, Morgan JI, Curran T (1989): Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain. J Neurosci Res 24:72-80.
33. Sperber EF, Moshé SL (1988): Age-related differences in seizure susceptibility to flurothyl. Dev Brain Res 39:295-297.
34. Szot P, White SS, Veith RC (1997): Effect of pentylenetetrazol on the expression of tyrosine hydroxylase mRNA and norepinephrine and dopamine transporter mRNA. Mol Brain Res 44: 46-54.
35. Tempel BL (1995): Candidate genes in the childhood epilepsies: Molecular biology of channels and receptors; in Schwartzkroin PA, Moshé SL, Noebels JL, Swann JW (eds): Brain Development and Epilepsy. New York, Oxford University Press, pp 171-194.
36. Tempel BL, Jan YN, Jan LY (1988): Cloning of a probable potassium channel gene from mouse brain. Nature 332:837-839.
37. Tempel BL, Papazian DM, Schwarz TL, Jan YN, Jan LY (1987): Sequence of probable potassium-channel component encoded at the Shaker locus of Drosophila. Science 237:770-775.
38. Truitt EB, Ebesberg EM, Ling ASG (1960): Measurement of brain excitability by use of hexaflurodiethyl ether (Indoclon). J Pharmacol Exp Ther 129:445-453.
39. + channel proteins, to synaptic terminals, somata and dendrites in the mouse brain. J Neurosci 14:4588-4599.
40. Winston SM, Hayward MD, Nestler EJ, Duman R (1990): Chronic electroconvulsive seizures down-regulate expression of the immediate early genes c-fos and c-jun in rat cerebral cortex. J Neurochem 54:1920-1925.
41. Zuberi SM, Stephenson J, McWilliam R, de Silva R, Jamieson A, Tolmie J (1997): Episodic ataxia type 1 and epilepsy: Manifestations of a potassium channelopathy in a Scottish family. Epilepsia 38(suppl 3):104.