The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvβ1

Neuron

Volumn 49, Issue 5, 2006, Pages 697-706

  Schulte, Uwe ^b   Thumfart, Jörg Oliver ^a   Klöcker, Nikolaj ^a   Sailer, Claudia A ^a,c   Bildl, Wolfgang ^a   Biniossek, Martin ^a   Dehn, Doris ^d   Deller, Thomas ^d   Eble, Silke ^a   Abbass, Karen ^b   Wangler, Tanja ^b   Knaus, Hans Günther ^c   Fakler, Bernd ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b LOGOPHARM GMBH   (Germany)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; LEUCINE RICH GLIOMA INACTIVATED GENE 1 PROTEIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KV1; VOLTAGE GATED POTASSIUM CHANNEL SUBUNIT KVBETA1;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL KINETICS; COMPLEX FORMATION; CONTROLLED STUDY; EPILEPTIC DISCHARGE; GENE INACTIVATION; GENETIC LINKAGE; HIPPOCAMPUS; NERVE ENDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN CONTENT; PROTEIN DEFECT; PROTEIN FUNCTION; RAT; TEMPORAL LOBE EPILEPSY;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; BRAIN; BRAIN CHEMISTRY; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; HUMANS; IMMUNOHISTOCHEMISTRY; KV1.1 POTASSIUM CHANNEL; KV1.2 POTASSIUM CHANNEL; MASS SPECTROMETRY; MEMBRANE POTENTIALS; MUTAGENESIS; MUTATION; NEURAL INHIBITION; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; PROTEINS; RATS; SEQUENCE ALIGNMENT; SILVER STAINING; TRANSFECTION; XENOPUS;

EID: 33344456574     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2006.01.033     Document Type: Article

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