Testosterone metabolism to 5α-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes

British Journal of Dermatology

Volumn 156, Issue 3, 2007, Pages 428-432

  Makrantonaki, E ^a   Zouboulis, C C ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b DESSAU MEDICAL CENTER   (Germany)

Author keywords

5 reductase inhibitor; Androgens; Lipids; Peroxisome proliferator activated receptors; Sebocytes

Indexed keywords

4 METHYLUMBELLIFERYL HEPTANOATE; 8 CHLORO 1,2,3,4,4A,5,6,10B OCTAHYDRO 4 METHYLBENZO[F]QUINOLIN 3(2H) ONE; ANDROSTANOLONE; HEPTANOIC ACID DERIVATIVE; LACTATE DEHYDROGENASE; LIGAND; LINOLEIC ACID; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; UNCLASSIFIED DRUG; 17 OXOSTEROID; 5 DIHYDRORUBROSTERONE; 5-DIHYDRORUBROSTERONE; ANDROSTANE DERIVATIVE; QUINOLONE DERIVATIVE; STEROID 5ALPHA REDUCTASE;

ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID ANALYSIS; LIPOGENESIS; PRIORITY JOURNAL; SEBACEOUS GLAND; SUPERNATANT; TESTOSTERONE METABOLISM; TESTOSTERONE SYNTHESIS; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; METABOLISM;

17-KETOSTEROIDS; ANDROSTANOLS; CELL PROLIFERATION; CELLS, CULTURED; DRUG SYNERGISM; HUMANS; LIGANDS; LINOLEIC ACID; LIPIDS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; QUINOLONES; SEBACEOUS GLANDS; TESTOSTERONE; TESTOSTERONE 5-ALPHA-REDUCTASE;

EID: 33846953513     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2006.07671.x     Document Type: Article

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