-
1
-
-
0242352380
-
Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration
-
Carrascosa C., Torres-Aleman I., Lopez-Lopez C., Carro E., Espejo L., Torrado S., et al. Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration. Biomaterials 25 4 (2004) 707-714
-
(2004)
Biomaterials
, vol.25
, Issue.4
, pp. 707-714
-
-
Carrascosa, C.1
Torres-Aleman, I.2
Lopez-Lopez, C.3
Carro, E.4
Espejo, L.5
Torrado, S.6
-
2
-
-
0345862282
-
Insulin-like growth factor I and Alzheimer's disease: therapeutic prospects?
-
Carro E.T.-A.I. Insulin-like growth factor I and Alzheimer's disease: therapeutic prospects?. Exp Rev Neurother 4 1 (2004) 79-86
-
(2004)
Exp Rev Neurother
, vol.4
, Issue.1
, pp. 79-86
-
-
Carro, E.T.-A.I.1
-
3
-
-
0035426212
-
Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy
-
Carro E., Trejo J.L., Busiguina S., and Torres-Aleman I. Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy. J Neurosci 21 15 (2001) 5678-5684
-
(2001)
J Neurosci
, vol.21
, Issue.15
, pp. 5678-5684
-
-
Carro, E.1
Trejo, J.L.2
Busiguina, S.3
Torres-Aleman, I.4
-
4
-
-
0036917631
-
Serum insulin-like growth factor I regulates brain amyloid-beta levels
-
Carro E., Trejo J.L., Gomez-Isla T., LeRoith D., and Torres-Aleman I. Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat Med 8 12 (2002) 1390-1397
-
(2002)
Nat Med
, vol.8
, Issue.12
, pp. 1390-1397
-
-
Carro, E.1
Trejo, J.L.2
Gomez-Isla, T.3
LeRoith, D.4
Torres-Aleman, I.5
-
5
-
-
0030710114
-
The 'amyloid cascade hypothesis' of AD: decoy or real McCoy?
-
Davis J.N., and Chisholm J.C. The 'amyloid cascade hypothesis' of AD: decoy or real McCoy?. Trends Neurosci 20 12 (1997) 558-559
-
(1997)
Trends Neurosci
, vol.20
, Issue.12
, pp. 558-559
-
-
Davis, J.N.1
Chisholm, J.C.2
-
6
-
-
0025269152
-
Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity
-
DeKosky S.T., and Scheff S.W. Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Ann Neurol 27 5 (1990) 457-464
-
(1990)
Ann Neurol
, vol.27
, Issue.5
, pp. 457-464
-
-
DeKosky, S.T.1
Scheff, S.W.2
-
7
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
Dodart J.C., Bales K.R., Gannon K.S., Greene S.J., DeMattos R.B., Mathis C., et al. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat Neurosci 5 5 (2002) 452-457
-
(2002)
Nat Neurosci
, vol.5
, Issue.5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
DeMattos, R.B.5
Mathis, C.6
-
8
-
-
0035942734
-
Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory
-
Dubnau J., Grady L., Kitamoto T., and Tully T. Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory. Nature 411 6836 (2001) 476-480
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 476-480
-
-
Dubnau, J.1
Grady, L.2
Kitamoto, T.3
Tully, T.4
-
9
-
-
0141542236
-
Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia
-
Fernandez A.M., de la Vega A.G., and Torres-Aleman I. Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia. Proc Natl Acad Sci USA 95 3 (1998) 1253-1258
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.3
, pp. 1253-1258
-
-
Fernandez, A.M.1
de la Vega, A.G.2
Torres-Aleman, I.3
-
10
-
-
0034281379
-
Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase-deficient mouse together with monoamine changes in cerebellum and ventral striatum
-
Frisch C., Dere E., Silva M.A., Godecke A., Schrader J., and Huston J.P. Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase-deficient mouse together with monoamine changes in cerebellum and ventral striatum. J Neurosci 20 17 (2000) 6694-6700
-
(2000)
J Neurosci
, vol.20
, Issue.17
, pp. 6694-6700
-
-
Frisch, C.1
Dere, E.2
Silva, M.A.3
Godecke, A.4
Schrader, J.5
Huston, J.P.6
-
11
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 5580 (2002) 353-356
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
12
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274 5284 (1996) 99-102
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
-
13
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase
-
Jankowsky J.L., Fadale D.J., Anderson J., Xu G.M., Gonzales V., Jenkins N.A., et al. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Hum Mol Genet 13 2 (2004) 159-170
-
(2004)
Hum Mol Genet
, vol.13
, Issue.2
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
-
14
-
-
0035468905
-
New developments in animal models of Alzheimer's disease
-
Janus C., Phinney A.L., Chishti M.A., and Westaway D. New developments in animal models of Alzheimer's disease. Curr Neurol Neurosci Rep 1 5 (2001) 451-457
-
(2001)
Curr Neurol Neurosci Rep
, vol.1
, Issue.5
, pp. 451-457
-
-
Janus, C.1
Phinney, A.L.2
Chishti, M.A.3
Westaway, D.4
-
15
-
-
0034091707
-
Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation
-
Kumar-Singh S., Dewachter I., Moechars D., Lubke U., De Jonghe C., Ceuterick C., et al. Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation. Neurobiol Dis 7 1 (2000) 9-22
-
(2000)
Neurobiol Dis
, vol.7
, Issue.1
, pp. 9-22
-
-
Kumar-Singh, S.1
Dewachter, I.2
Moechars, D.3
Lubke, U.4
De Jonghe, C.5
Ceuterick, C.6
-
16
-
-
0032888131
-
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
-
Lue L.F., Kuo Y.M., Roher A.E., Brachova L., Shen Y., Sue L., et al. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease. Am J Pathol 155 3 (1999) 853-862
-
(1999)
Am J Pathol
, vol.155
, Issue.3
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
-
17
-
-
0035830408
-
Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease
-
Masliah E., Mallory M., Alford M., DeTeresa R., Hansen L.A., McKeel Jr. D.W., et al. Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease. Neurology 56 1 (2001) 127-129
-
(2001)
Neurology
, vol.56
, Issue.1
, pp. 127-129
-
-
Masliah, E.1
Mallory, M.2
Alford, M.3
DeTeresa, R.4
Hansen, L.A.5
McKeel Jr., D.W.6
-
18
-
-
0041856595
-
Epidemiology of neurodegeneration
-
Mayeux R. Epidemiology of neurodegeneration. Annu Rev Neurosci 26 (2003) 81-104
-
(2003)
Annu Rev Neurosci
, vol.26
, pp. 81-104
-
-
Mayeux, R.1
-
19
-
-
0035863456
-
Modulating astrogliosis after neurotrauma
-
McGraw J., Hiebert G.W., and Steeves J.D. Modulating astrogliosis after neurotrauma. J Neurosci Res 63 2 (2001) 109-115
-
(2001)
J Neurosci Res
, vol.63
, Issue.2
, pp. 109-115
-
-
McGraw, J.1
Hiebert, G.W.2
Steeves, J.D.3
-
20
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean C.A., Cherny R.A., Fraser F.W., Fuller S.J., Smith M.J., Beyreuther K., et al. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 46 6 (1999) 860-866
-
(1999)
Ann Neurol
, vol.46
, Issue.6
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
-
21
-
-
0021173996
-
Developments of a water-maze procedure for studying spatial learning in the rat
-
Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Meth 11 1 (1984) 47-60
-
(1984)
J Neurosci Meth
, vol.11
, Issue.1
, pp. 47-60
-
-
Morris, R.1
-
22
-
-
0036808469
-
Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer's disease
-
Mufson E.J., Counts S.E., and Ginsberg S.D. Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer's disease. Neurochem Res 27 10 (2002) 1035-1048
-
(2002)
Neurochem Res
, vol.27
, Issue.10
, pp. 1035-1048
-
-
Mufson, E.J.1
Counts, S.E.2
Ginsberg, S.D.3
-
23
-
-
0035930579
-
Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton
-
Okamoto P.M., Gamby C., Wells D., Fallon J., and Vallee R.B. Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton. J Biol Chem 276 51 (2001) 48458-48465
-
(2001)
J Biol Chem
, vol.276
, Issue.51
, pp. 48458-48465
-
-
Okamoto, P.M.1
Gamby, C.2
Wells, D.3
Fallon, J.4
Vallee, R.B.5
-
24
-
-
0034623956
-
Insulin-like growth factor-I stimulates dephosphorylation of Ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B)
-
Pons S., and Torres-Aleman I. Insulin-like growth factor-I stimulates dephosphorylation of Ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B). J Biol Chem 275 49 (2000) 38620-38625
-
(2000)
J Biol Chem
, vol.275
, Issue.49
, pp. 38620-38625
-
-
Pons, S.1
Torres-Aleman, I.2
-
25
-
-
0141707862
-
PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation
-
Richards J.G., Higgins G.A., Ouagazzal A.M., Ozmen L., Kew J.N., Bohrmann B., et al. PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation. J Neurosci 23 26 (2003) 8989-9003
-
(2003)
J Neurosci
, vol.23
, Issue.26
, pp. 8989-9003
-
-
Richards, J.G.1
Higgins, G.A.2
Ouagazzal, A.M.3
Ozmen, L.4
Kew, J.N.5
Bohrmann, B.6
-
26
-
-
0030972777
-
Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma
-
Rostworowski M., Balasingam V., Chabot S., Owens T., and Yong V.W. Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma. J Neurosci 17 10 (1997) 3664-3674
-
(1997)
J Neurosci
, vol.17
, Issue.10
, pp. 3664-3674
-
-
Rostworowski, M.1
Balasingam, V.2
Chabot, S.3
Owens, T.4
Yong, V.W.5
-
27
-
-
0035950225
-
Clearing the Brain's Amyloid Cobwebs
-
Selkoe D.J. Clearing the Brain's Amyloid Cobwebs. Neuron 32 2 (2001) 177-180
-
(2001)
Neuron
, vol.32
, Issue.2
, pp. 177-180
-
-
Selkoe, D.J.1
-
28
-
-
0034521392
-
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
-
Shibata M., Yamada S., Kumar S.R., Calero M., Bading J., Frangione B., et al. Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest 106 12 (2000) 1489-1499
-
(2000)
J Clin Invest
, vol.106
, Issue.12
, pp. 1489-1499
-
-
Shibata, M.1
Yamada, S.2
Kumar, S.R.3
Calero, M.4
Bading, J.5
Frangione, B.6
-
29
-
-
0033178980
-
Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics
-
Strazielle N., and Ghersi-Egea J.F. Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics. J Neurosci 19 15 (1999) 6275-6289
-
(1999)
J Neurosci
, vol.19
, Issue.15
, pp. 6275-6289
-
-
Strazielle, N.1
Ghersi-Egea, J.F.2
-
30
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki N., Cheung T.T., Cai X.D., Odaka A., Otvos Jr. L., Eckman C., et al. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 264 5163 (1994) 1336-1340
-
(1994)
Science
, vol.264
, Issue.5163
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
-
31
-
-
1642379156
-
Role of insulin-like growth factor I signaling in neurodegenerative diseases
-
Trejo J.L., Carro E., Garcia-Galloway E., and Torres-Aleman I. Role of insulin-like growth factor I signaling in neurodegenerative diseases. J Mol Med 82 3 (2004) 156-162
-
(2004)
J Mol Med
, vol.82
, Issue.3
, pp. 156-162
-
-
Trejo, J.L.1
Carro, E.2
Garcia-Galloway, E.3
Torres-Aleman, I.4
-
32
-
-
11844258289
-
Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span
-
von Kienlin M., Kunnecke B., Metzger F., Steiner G., Richards J.G., Ozmen L., et al. Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span. Neurobiol Dis 18 1 (2005) 32-39
-
(2005)
Neurobiol Dis
, vol.18
, Issue.1
, pp. 32-39
-
-
von Kienlin, M.1
Kunnecke, B.2
Metzger, F.3
Steiner, G.4
Richards, J.G.5
Ozmen, L.6
-
33
-
-
0346156091
-
Synaptic frailty and clathrin-mediated synaptic vesicle trafficking in Alzheimer's disease
-
Yao P.J. Synaptic frailty and clathrin-mediated synaptic vesicle trafficking in Alzheimer's disease. Trends Neurosci 27 1 (2004) 24-29
-
(2004)
Trends Neurosci
, vol.27
, Issue.1
, pp. 24-29
-
-
Yao, P.J.1
-
34
-
-
0037343844
-
Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease
-
Yao P.J., Zhu M., Pyun E.I., Brooks A.I., Therianos S., Meyers V.E., et al. Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease. Neurobiol Dis 12 2 (2003) 97-109
-
(2003)
Neurobiol Dis
, vol.12
, Issue.2
, pp. 97-109
-
-
Yao, P.J.1
Zhu, M.2
Pyun, E.I.3
Brooks, A.I.4
Therianos, S.5
Meyers, V.E.6
-
35
-
-
0030604067
-
Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier
-
Zlokovic B.V. Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier. Life Sci 59 18 (1996) 1483-1497
-
(1996)
Life Sci
, vol.59
, Issue.18
, pp. 1483-1497
-
-
Zlokovic, B.V.1
|