Induction of collagen by estradiol: Difference between sun-protected and photodamaged human skin in vivo

Archives of Dermatology

Volumn 144, Issue 9, 2008, Pages 1129-1140

  Rittié, Laure ^a   Kang, Sewon ^a   Voorhees, John J ^a   Fisher, Gary J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GPR30; GREB1; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ANATOMY; ARTICLE; CHEMICAL ANALYSIS; CLINICAL TRIAL; CONTROLLED STUDY; CUTANEOUS PARAMETERS; ENZYME LINKED IMMUNOSORBENT ASSAY; FACE; FEMALE; FOREARM; GENE; GENOMICS; HIP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SKIN; SKIN BIOPSY; SKIN DEFECT; SUN; SYNTHESIS; UNIVERSITY HOSPITAL; VOLUNTEER;

ADMINISTRATION, TOPICAL; AGED; AGED, 80 AND OVER; COLLAGEN TYPE I; COLLAGEN TYPE III; DRUG ADMINISTRATION SCHEDULE; ENVIRONMENTAL EXPOSURE; ESTRADIOL; FACE; FEMALE; FOREARM; GENE EXPRESSION REGULATION; HIP; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; POSTMENOPAUSE; PROCOLLAGEN; RADIATION PROTECTION; RECEPTORS, ESTROGEN; SKIN; SKIN AGING; SUNLIGHT; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 51949096280     PISSN: 0003987X     EISSN: 0003987X     Source Type: Journal    
DOI: 10.1001/archderm.144.9.1129     Document Type: Article

References (60)

1. Yaar M, Eller MS, Glchrest BA. Fifty years of skin aging. J Investig Dermatol Symp Proc. 2002;7(1):51-58.
2. Lavker RM. Cutaneous aging: chronologic versus photoaging. In: Gilchrest BA, ed. Photodamage. Cambridge, MA: Blackwell Science: 1975:123-135.
3. Rittié L, Fisher GJ. UV-light-induced signal cascades and skin aging. Ageing Res Rev. 20021 (4):705-720.
4. Eckes B, Zweers MC, Zhang ZG, et al. Mechanical tension and integrin alpha 2 beta 1 regulate fibroblast functions. J Investig Dermatol Symp Proc. 2006; 11(1):66-72.
5. Varani J. Dame MK, Rittié L, et al. Decreased collagen production In chronologically aged skin: roles of age-dependent alteration In fibroblast function and defective mechanical stimulation. Am J Pathol. 2006;168(6):1861-1868.
6. Varani J, Perone P, Fligiel SE, Fisher GJ, Voorhees JJ. Inhibition of type I procollagen production In photodamage: correlation between presence of high molecular weight collagen fragments and reduced procollagen synthesis. J Invest Dermatol. 2002; 119(1):122-129.
7. Varani J, Spearman D, Perone P, et al. Inhibition of type I procollagen synthesis by damaged collagen In photoaged skin and by collagenase-degraded collagen In vitro. AmJPathol. 2001;158(3):931-942.
8. Wang F, Garza LA, Kang S, et al. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler Injections In photodamaged human skin. Arch Dermatol. 2007;143(2)155-163.
9. Rittié L, Fisher GJ, Voorhees JJ. Retinoid therapy for photoaging. In: Gilchrest BA, Krutman J, eds. Skin Ageing. Berlin, Germany: Springer-Verlag; 2006143-156.
10. Orringer JS, Kang S, Johnson TM, et al. Connective tissue remodeling Induced by carbon dioxide laser resurfacing of photodamaged human skin. Arch Dermatol. 2004140(11)1326-1332.
11. Bolognia JL, Braverman IM, Rousseau ME, Sarrel PM. Skin changes In menopause. Maturitas. 1989;11(4):295-304.
12. Piérard GE, Letawe C, Dowlati A, Piérard-Franchimont C. Effect of hormone replacement therapy for menopause on the mechanical properties of skin. J Am Geriatr Soc. 1995;43(6):662-665.
13. Sumino H, Ichikawa S, Abe M, et al. Effects of aging and postmenopausal hy-poestrogenism on skin elasticity and bone mineral density In Japanese women. Endocr J. 2004;51(2)159-164.
14. Chotnopparatpattara P, Panyakhamlerd K.TaechakraIchana N, Tantivatana J, Chai-kittisilpa S, Limpaphayom KK. An effect of hormone replacement therapy on skin thickness In early postmenopausal women. J Med Assoc Thai. 2001;84(9): 1275-1280.
15. Brincat M, Moniz CF, Studd JW, Darby AJ, Magos A, Cooper D. Sex hormones and skin collagen content In postmenopausal women. Br Med J (Clin Res Ed). 1983;287(6402):1337-1338.
16. Castelo-Branco C, Duran M. Gonzalez-Merlo J. Skin collagen changes related to age and hormone replacement therapy. Maturitas. 1992;15(2):113-119.
17. Affinito P, Palomba S, Sorrentino C, et al. Effects of postmenopausal hypoes-trogenism on skin collagen. Maturitas. 1999:33(3):239-247.
18. Piérard-Franchimont C, Letawe C, Goffin V, Piérard GE. Skin water-holding capacity and transdermal estrogen therapy for menopause: a pilot study. Maturitas. 1995:22(2)151-154.
19. Dunn LB, Damesyn M, Moore AA, Reuben DB, Greendale GA. Does estrogen prevent skin aging? results from the First National Health and Nutrition Examination Survey (NHANES I). Arch Dermatol. 1997;133(3):339-342.
20. Sator PG, Schmidt JB, Sator MO, Huber JC, Honigsmann H. The influence of hormone replacement therapy on skin ageing: a pilot study. Maturitas. 2001; 39(1):43-55.
21. Schmidt JB, Binder M, Demschik G, Bieglmayer C, Reiner A. Treatment of skin aging with topical estrogens. Int J Dermatol. 1996;35(9):669-674.
22. Sumino H, Ichikawa S, Abe M, Endo Y, Ishikawa O, Kurabayashi M. Effects of aging, menopause, and hormone replacement therapy on forearm skin elasticity In women. J Am GeriatrSoc. 2004;52(6):945-949.
23. Wolff EF, Narayan D, Taylor HS. Long-term effects of hormone therapy on skin rigidity and wrinkles. Fertil Steril. 2005;84(2):285-288.
24. Sauerbronn AV, Fonseca AM, Bagnoli VR, Saldiva PH, Pinotti JA. The effects of systemic hormonal replacementtherapy on the skin of postmenopausal women. Int J Gynaecol Obstet. 2000:68(1 ):35-41.
25. Callens A, Vaillant L, Lecomte P, Berson M, Gall Y, Lorette G. Does hormonal skin aging exist? a study of the Influence of different hormone therapy regimens on the skin of postmenopausal women using non-Invasive measurement techniques. Dermatology. 1996; 193(4):289-294.
26. Maheux R. Naud F, Rioux M, et al. A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness. Am J Obstet Gynecol. 1994;170(2):642-649.
27. Brincat M, Moniz CJ, Studd JW, et al. Long-term effects of the menopause and sex hormones on skin thickness. Br J Obstet Gynaecol. 1985;92(3):256-259.
28. Brincat M, Versi E, Moniz CF, Magos A, de Trafford J, Studd JW. Skin collagen changes In postmenopausal women receiving different regimens of estrogen therapy. Obstet Gynecol. 1987:70(1)123-127.
29. Punnonen R. Effect of castration and peroral estrogen therapy on the skin. Ada Obstet Gynecol Scand Suppl. 1972;21:3-44.
30. Haapasaari KM. Raudaskoski T, Kallioinen M. et al. Systemic therapy with estrogen or estrogen with progestin has no effect on skin collagen In postmenopausal women. Maturitas. 1997;27(2):153-162.
31. Oikarinen A. Systemic estrogens have no conclusive beneficial effect on human skin connective tissue. Acta Obstet Gynecol Scand. 2000;79(4):250-254.
32. Varila E, Rantala I, Oikarinen A, et al. The effect of topical oestradiol on skin collagen of postmenopausal women. Br J Obstet Gynaecol. 1995;102(12):985-989.
33. Son ED, Lee JY, Lee S, et al. Topical application of 17β-estradiol increases extracellular matrix protein synthesis by stimulating TGF-β signaling In aged human skin in vivo. J Invest Dermatol. 2005124(6)1149-1161.
34. Creidi P, Faivre B, Agache P, Richard E, Haudiquet V, Sauvanet JP. Effect of a conjugated oestrogen (Premarin) cream on ageing facial skin: a comparative study with a placebo cream. Maturitas. 1994;19(3):211-223.
35. Fuchs KO, Solis O, Tapawan R, Paranjpe J. The effects of an estrogen and gly-colic acid cream on the facial skin of postmenopausal women: a randomized his-tologic study. Cutis. 2003;71(6):481-488.
36. Jemec GB, Serup J. Short-term effects of topical 17 beta-oestradiol on human post-menopausal skin. Maturitas. 1989;11(3):229-234.
37. Taylor HS. Judging a book by Its cover: estrogen and skin aging. Fertil Steril. 2005;84(2):295. dol 10.1016/j.fertnstert.2005.04.017.
38. Draelos ZD. Topical and oral estrogens revisited for antiaging purposes. Fertil Steril. 2005:84(2):291-292.
39. Naftolin F. Prevention during the menopause Is critical for good health: skin studies support protracted hormone therapy. Fertil Steril. 2005;84(2):293-294.
40. Raine-Fenning NJ, Brincat MP, Muscat-Baron Y. Skin aging and menopause: Implications for treatment. Am J Clin Dermatol. 2003;4(6):371-378.
41. Sator PG, Schmidt JB, Rabe T, Zouboulis CC. Skin aging and sex hormones In women-clinical perspectives for intervention by hormone replacement therapy. Exp Dermatol. 2004;13(suppl 4):36-40.
42. Kushner PJ, Webb P, Uht RM, Liu MM, Price RH. Estrogen receptor action through target genes with classical and alternative response elements. Pure Appl Chem. 2003;75(11-12)1757-1769 http://media.lupac.org/publlcations/pac/ 2003/pdfA7511×1757.pdf. Accessed August 27. 2007.
43. Rae JM. Johnson MD. What does an orphan G-protein-coupled receptor have to do with estrogen? Breast Cancer Res. 2005;7(6):243-244.
44. Jimenez SA, Varga J, Olsen A, et al. Functional analysis of human α1(l) procollagen gene promoter: differential activity In collagen-producing and -nonproducing cells and response to transforming growth factor βJ Biol Chem. 1994; 269(17)12684-12691.
45. Quan T, He T, Kang S, Voorhees JJ, Fisher GJ. Solar ultraviolet Irradiation reduces collagen In photoaged human skin by blocking transforming growth factor-β type II receptor/Smad signaling. Am J Pathol. 2004;165(3):741-751.
46. Rittié L, Varani J, Kang S, Voorhees JJ, Fisher GJ. Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGFand amphiregulin in human skin in vivo. J Invest Dermatol. 2006;126(4):732-739.
47. Nimni ME. Collagen: structure, function, and metabolism In normal and fibrotic tissues. Semin Arthritis Rheum. 1983;13(1 ):1-86.
48. Raftogianis R, Creveling C, Weinshilboum R, Weisz J. Estrogen metabolism by conjugation. J Natl Cancer Inst Monogr. 2000;(27):113-124.
49. Peltoketo H, Vihko P, Vihko R. Regulation of estrogen action: role of 17 beta-hydroxysteroid dehydrogenases. Vitam Horm. 1999:55:353-398.
50. Iwamori M. Estrogen sulfatase. Methods Enzymol. 2005;400:293-302.
51. Gamage N, Barnett A, Hempel N, et al. Human sulfotransferases and their role In chemical metabolism. Toxicol Sci. 2006;90(1):5-22.
52. Zhu BT, Lee AJ. NADPH-dependent metabolism of 17β-estradlol and estrone to polar and nonpolar metabolites by human tissues and cytochrome P450 isoforms. Steroids. 2005;70(4):225-244.
53. Bourdeau V, Deschenes J, Metivier R, et al. Genome-wide Identification of high-affinity estrogen response elements In human and mouse. Mol Endocrinol. 2004; 18(6):1411-1427.
54. Meyer WJ III, Henneman DH, Keiser HR, Bartter FC. 17 Alpha estradiol: separation of estrogen effect on collagen from other clinical and biochemical effects In man. Res Commun Chem Pathol Pharmacol. 1976;13(4):685-695.
55. Patriarca MT, Goldman KZ, Dos Santos JM, et al. Effects of topical estradiol on the facial skin collagen of postmenopausal women under oral hormone therapy: a pilot study. EurJ Obstet Gynecol Reprod Biol. 2007;130(2):202-205.
56. Hasselquist MB, Goldberg N, Schroeter A, Spelsberg TC. Isolation and characterization of the estrogen receptor in human skin. J Clin Endocrinol Metab. 1980; 50(1):76-82.
57. Punnonen R, Lövgren T, Kouvonen I. Demonstration of estrogen receptors in the skin. J Endocrinol Invest. 1980:3(3):217-221.
58. Pelletier G, Ren L. Localization of sex steroid receptors in human skin. Histol Histopathol. 2004;19(2):629-636.
59. Zouboulis CC, Chen WC, Thornton MJ, Qin K, Rosenfield R. Sexual hormones in human skin. Horm Metab Res. 2007;39(2):85-95.
60. Hall G, Phillips TJ. Estrogen and skin: the effects of estrogen, menopause, and hormone replacement therapy on the skin. J Am Acad Dermatol. 2005;53(4): 555-568.