IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury

Experimental Neurology

Volumn 215, Issue 1, 2009, Pages 53-59

  Hollis II, Edmund R ^a   Lu, Paul ^a,b   Blesch, Armin ^a   Tuszynski, Mark H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Axon regeneration; Growth factor; NBI 31772; Spinal cord injury; Subcortical lesion

Indexed keywords

SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL REGENERATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; FEMALE; FISCHER 344 RAT; GENE DELIVERY SYSTEM; GENE TARGETING; NERVE CELL; NERVE FIBER GROWTH; NERVE FIBER TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL TRACT; RAT; SPINAL CORD INJURY;

ANIMALS; ANIMALS, NEWBORN; BONE MARROW CELLS; CATECHOLS; CELL SURVIVAL; CELLS, CULTURED; CHOLERA TOXIN; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GLIAL FIBRILLARY ACIDIC PROTEIN; INSULIN-LIKE GROWTH FACTOR I; ISOQUINOLINES; NERVE REGENERATION; NEURONS; PYRAMIDAL TRACTS; RATS; RATS, INBRED F344; SPINAL CORD INJURIES; TRANSFECTION; TYROSINE 3-MONOOXYGENASE;

EID: 57449092483     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.09.014     Document Type: Article

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