The role of telomeres in skin aging/photoaging

Micron

Volumn 35, Issue 3, 2004, Pages 155-159

  Kosmadaki, M G ^a,b   Gilchrest, B A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

Author keywords

Senescencee; Sun damage; T oligos

Indexed keywords

EID: 1242299775     PISSN: 09684328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micron.2003.11.002     Document Type: Review

References (46)

1. Ahmed A., Tollefsbol T. Telomeres and telomerase: basic science implications for aging. J. Am. Geriatr. Soc. 49:2001;1105-1109.
2. Allsopp R.C., Vaziri H., Patterson C., Goldstein S., Younglai E.V., Futcher A.B., Greider C.W., Harley C.B. Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl Acad. Sci. USA. 89:1992;10114-10118.
3. Baur J.A., Zou Y., Shay J.W., Wright W.E. Telomere position effect in human cells. Science. 292:2001;2075-2077.
4. Blackburn E.H. Telomere states and cell fates. Nature. 408:2000;53-56.
5. Blackburn E.H. Switching and signaling at the telomere. Cell. 106:2001;661-673.
6. Bodnar A.G., Ouellette M., Frolkis M., Holt S.E., Chiu C.P., Morin G.B., Harley C.B., Shay J.W., Lichtsteiner S., Wright W.E. Extension of life-span by introduction of telomerase into normal human cells. Science. 279:1998;349-352.
7. Cadet J., Douki T., Pouget J.P., Ravanat J.L., Sauvaigo S. Effects of uv and visible radiations on cellular DNA. Curr. Probl. Dermatol. 29:2001;62-73.
8. Campisi J. Replicative senescence: an old lives' tale? Cell. 84:1996;497-500.
9. Chan S.W., Blackburn E.H. New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin. Oncogene. 21:2002;553-563.
10. Eller M.S., Ostrom K., Gilchrest B.A. DNA damage enhances melanogenesis. Proc. Natl Acad. Sci. USA. 93:1996;1087-1092.
11. Eller M.S., Puri N., Hadshiew I.M., Venna S.S., Gilchrest B.A. Induction of apoptosis by telomere 3' overhang-specific DNA. Exp. Cell Res. 276:2002;185-193.
12. Eller M.S., Li G.Z., Firoozabadi R., Puri N., Gilchrest B.A. Induction of a p95/nbs1-mediated s phase checkpoint by telomere 3' overhang specific DNA. Faseb J. 17:2003;152-162.
13. Fisher G.J., Datta S., Wang Z., Li X.Y., Quan T., Chung J.H., Kang S., Voorhees J.J. C-jun-dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid. J. Clin. Invest. 106:2000;663-670.
14. Fry M., Loeb L.A. Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile x syndrome repeat sequence d(cgg)n. J. Biol. Chem. 274:1999;12797-12802.
15. Funk W.D., Wang C.K., Shelton D.N., Harley C.B., Pagon G.D., Hoeffler W.K. Telomerase expression restores dermal integrity to in vitro-aged fibroblasts in a reconstituted skin model. Exp. Cell Res. 258:2000;270-278.
16. Griffith J.D., Comeau L., Rosenfield S., Stansel R.M., Bianchi A., Moss H., de Lange T. Mammalian telomeres end in a large duplex loop. Cell. 97:1999;503-514.
17. Harley C.B., Futcher A.B., Greider C.W. Telomeres shorten during ageing of human fibroblasts. Nature. 345:1990;458-460.
18. Hart R.W., Setlow R.B. Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species. Proc. Natl Acad. Sci. USA. 71:1974;2169-2173.
19. Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37:1965;614-635.
20. Hayflick L. The cellular basis of biological aging. F.C.H.L. Handbook of the Biology of Aging. 1977;159-179 Van Nostrand Reinhold, NewYork.
21. Hayfick L., Moorehead P.S. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25:1961;585-621.
22. Hisama F.M., Chen Y.H., Meyn M.S., Oshima J., Weissman S.M. Wrn or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed werner syndrome fibroblasts. Cancer Res. 60:2000;2372-2376.
23. Jiang X.R., Jimenez G., Chang E., Frolkis M., Kusler B., Sage M., Beeche M., Bodnar A.G., Wahl G.M., Tlsty T.D., Chiu C.P. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat. Genet. 21:1999;111-114.
24. Karlseder J., Broccoli D., Dai Y., Hardy S., de Lange T. P53- and atm-dependent apoptosis induced by telomeres lacking trf2. Science. 283:1999;1321-1325.
25. Li G.Z., Eller M.S., Firoozabadi R., Gilchrest B.A. Evidence that exposure of the telomere 3' overhang sequence induces senescence. Proc. Natl Acad. Sci. USA. 100:2003;527-531.
26. Martindale J.L., Holbrook N.J. Cellular response to oxidative stress: signaling for suicide and survival. J. Cell Physiol. 192:2002;1-15.
27. Medrano E.E., Yang F., Boissy R., Farooqui J., Shah V., Matsumoto K., Nordlund J.J., Park H.Y. Terminal differentiation and senescence in the human melanocyte: repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes. Mol. Biol. Cell. 5:1994;497-509.
28. Ning Y., Xu J.F., Li Y., Chavez L., Riethman H.C., Lansdorp P.M., Weng N.P. Telomere length and the expression of natural telomeric genes in human fibroblasts. Hum. Mol. Genet. 12:2003;1329-1336.
29. Oikawa S., Kawanishi S. Site-specific DNA damage at ggg sequence by oxidative stress may accelerate telomere shortening. FEBS Lett. 453:1999;365-368.
30. Ouellette M.M., McDaniel L.D., Wright W.E., Shay J.W., Schultz R.A. The establishment of telomerase-immortalized cell lines representing human chromosome instability syndromes. Hum. Mol. Genet. 9:2000;403-411.
31. Patrick M.H., Snow J.M. Studies on thymine-derived uv photoproducts in DNA-ii. A comparative analysis of damage caused by 254 nm irradiation and triplet-state photosensitization. Photochem. Photobiol. 25:1977;373-384.
32. Pei X.H., Nakanishi Y., Takayama K., Bai F., Hara N. Benzo[a]pyrene activates the human p53 gene through induction of nuclear factor kappab activity. J. Biol. Chem. 274:1999;35240-35246.
33. Ramirez R.D., Wright W.E., Shay J.W., Taylor R.S. Telomerase activity concentrates in the mitotically active segments of human hair follicles. J. Invest. Dermatol. 108:1997;113-117.
34. Renzing J., Hansen S., Lane D.P. Oxidative stress is involved in the uv activation of p53. J. Cell Sci. 109:(Pt 5):1996;1105-1112.
35. Sekiguchi M., Tsuzuki T. Oxidative nucleotide damage: consequences and prevention. Oncogene. 21:2002;8895-8904.
36. Shen J.C., Gray M.D., Oshima J., Kamath-Loeb A.S., Fry M., Loeb L.A. Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide. J. Biol. Chem. 273:1998;34139-34144.
37. Sohal R.S., Allen R.G. Relationship between metabolic rate, free radicals, differentiation and aging: a unified theory. Basic Life Sci. 35:1985;75-104.
38. van Steensel B., Smogorzewska A., de Lange T. Trf2 protects human telomeres from end-to-end fusions. Cell. 92:1998;401-413.
39. Stein G.H., Dulic V. Molecular mechanisms for the senescent cell cycle arrest. J. Investig. Dermatol. Symp. Proc. 3:1998;14-18.
40. Stewart S.A., Hahn W.C., O'Connor B.F., Banner E.N., Lundberg A.S., Modha P., Mizuno H., Brooks M.W., Fleming M., Zimonjic D.B., Popescu N.C., Weinberg R.A. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proc. Natl Acad. Sci. USA. 99:2002;12606-12611.
41. Vulliamy T.J., Knight S.W., Mason P.J., Dokal I. Very short telomeres in the peripheral blood of patients with x-linked and autosomal dyskeratosis congenita. Blood Cells Mol. Dis. 27:2001;353-357.
42. Wright W.E., Shay J.W. Telomere positional effects and the regulation of cellular senescence. Trends Genet. 8:1992;193-197.
43. Yaar M., Gilchrest B.A. Aging of the skin. Freedberg I.M., Eisen A.Z., Wolff K., Austen K.F., Goldsmith L.A., Katz S.I. Fitzpatrick's Dermatology in General Medicine. 2003;1386-1398 McGraw-Hill, New York.
44. Yasumoto S., Kunimura C., Kikuchi K., Tahara H., Ohji H., Yamamoto H., Ide T., Utakoji T. Telomerase activity in normal human epithelial cells. Oncogene. 13:1996;433-439.
45. Yu C.E., Oshima J., Fu Y.H., Wijsman E.M., Hisama F., Alisch R., Matthews S., Nakura J., Miki T., Ouais S., Martin G.M., Mulligan J., Schellenberg G.D. Positional cloning of the Werner's syndrome gene. Science. 272:1996;258-262.
46. Zhan Q., Carrier F., Fornace A.J. Jr. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell Biol. 13:1993;4242-4250.