-
1
-
-
67649739079
-
Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis
-
Altamura S., Muckenthaler M.U. Iron toxicity in diseases of aging: Alzheimer's disease, Parkinson's disease and atherosclerosis. J. Alzheimers Dis. 2009, 16:879-895.
-
(2009)
J. Alzheimers Dis.
, vol.16
, pp. 879-895
-
-
Altamura, S.1
Muckenthaler, M.U.2
-
2
-
-
34547659803
-
Iron load and redox stress in skeletal muscle of aged rats
-
Altun M., Edstrom E., Spooner E., Flores-Moralez A., Bergman E., Tollet-Egnell P., Norstedt G., Kessler B.M., Ulfhake B. Iron load and redox stress in skeletal muscle of aged rats. Muscle Nerve 2007, 36:223-233.
-
(2007)
Muscle Nerve
, vol.36
, pp. 223-233
-
-
Altun, M.1
Edstrom, E.2
Spooner, E.3
Flores-Moralez, A.4
Bergman, E.5
Tollet-Egnell, P.6
Norstedt, G.7
Kessler, B.M.8
Ulfhake, B.9
-
3
-
-
67650091951
-
Age-related iron deposition in the basal ganglia: quantitative analysis in healthy subjects
-
Aquino D., Bizzi A., Grisoli M., Garavaglia B., Bruzzone M.G., Nardocci N., Savoiardo M., Chiapparini L. Age-related iron deposition in the basal ganglia: quantitative analysis in healthy subjects. Radiology 2009, 252:165-172.
-
(2009)
Radiology
, vol.252
, pp. 165-172
-
-
Aquino, D.1
Bizzi, A.2
Grisoli, M.3
Garavaglia, B.4
Bruzzone, M.G.5
Nardocci, N.6
Savoiardo, M.7
Chiapparini, L.8
-
4
-
-
0037069320
-
Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging
-
Atamna H., Killilea D.W., Killilea A.N., Ames B.N. Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:14807-14812.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14807-14812
-
-
Atamna, H.1
Killilea, D.W.2
Killilea, A.N.3
Ames, B.N.4
-
5
-
-
0035930604
-
Heme deficiency selectively interrupts assembly of mitochondrial complex IV in human fibroblasts: revelance to aging
-
Atamna H., Liu J., Ames B.N. Heme deficiency selectively interrupts assembly of mitochondrial complex IV in human fibroblasts: revelance to aging. J. Biol. Chem. 2001, 276:48410-48416.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48410-48416
-
-
Atamna, H.1
Liu, J.2
Ames, B.N.3
-
6
-
-
0037082142
-
The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age
-
Atamna H., Walter P.B., Ames B.N. The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age. Arch. Biochem. Biophys. 2002, 397:345-353.
-
(2002)
Arch. Biochem. Biophys.
, vol.397
, pp. 345-353
-
-
Atamna, H.1
Walter, P.B.2
Ames, B.N.3
-
7
-
-
34548790267
-
Myelin breakdown and iron changes in Huntington's disease: pathogenesis and treatment implications
-
Bartzokis G., Lu P.H., Tishler T.A., Fong S.M., Oluwadara B., Finn J.P., Huang D., Bordelon Y., Mintz J., Perlman S. Myelin breakdown and iron changes in Huntington's disease: pathogenesis and treatment implications. Neurochem. Res. 2007, 32:1655-1664.
-
(2007)
Neurochem. Res.
, vol.32
, pp. 1655-1664
-
-
Bartzokis, G.1
Lu, P.H.2
Tishler, T.A.3
Fong, S.M.4
Oluwadara, B.5
Finn, J.P.6
Huang, D.7
Bordelon, Y.8
Mintz, J.9
Perlman, S.10
-
8
-
-
38649100332
-
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG
-
Berletch J.B., Liu C., Love W.K., Andrews L.G., Katiyar S.K., Tollefsbol T.O. Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG. J. Cell Biochem. 2008, 103:509-519.
-
(2008)
J. Cell Biochem.
, vol.103
, pp. 509-519
-
-
Berletch, J.B.1
Liu, C.2
Love, W.K.3
Andrews, L.G.4
Katiyar, S.K.5
Tollefsbol, T.O.6
-
9
-
-
0021059279
-
Modification of age-induced changes in heme and hemoproteins by testosterone in male rats
-
Bitar M., Weiner M. Modification of age-induced changes in heme and hemoproteins by testosterone in male rats. Mech. Ageing Dev. 1983, 23:285-296.
-
(1983)
Mech. Ageing Dev.
, vol.23
, pp. 285-296
-
-
Bitar, M.1
Weiner, M.2
-
10
-
-
0028891637
-
Transport of iron and other transition metals into cells as revealed by a fluorescent probe
-
Breuer W., Epsztejn S., Millgram P., Cabantchik I.Z. Transport of iron and other transition metals into cells as revealed by a fluorescent probe. Am. J. Physiol. 1995, 268:C1354-C1361.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Breuer, W.1
Epsztejn, S.2
Millgram, P.3
Cabantchik, I.Z.4
-
11
-
-
0024366196
-
Iron absorption and phenolic compounds: importance of different phenolic structures
-
Brune M., Rossander L., Hallberg L. Iron absorption and phenolic compounds: importance of different phenolic structures. Eur. J. Clin. Nutr. 1989, 43:547-557.
-
(1989)
Eur. J. Clin. Nutr.
, vol.43
, pp. 547-557
-
-
Brune, M.1
Rossander, L.2
Hallberg, L.3
-
12
-
-
3042763187
-
Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity
-
Bulteau A.L., O'Neill H.A., Kennedy M.C., Ikeda-Saito M., Isaya G., Szweda L.I. Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity. Science 2004, 305:242-245.
-
(2004)
Science
, vol.305
, pp. 242-245
-
-
Bulteau, A.L.1
O'Neill, H.A.2
Kennedy, M.C.3
Ikeda-Saito, M.4
Isaya, G.5
Szweda, L.I.6
-
13
-
-
34548013116
-
The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload
-
Camaschella C., Campanella A., De F.L., Boschetto L., Merlini R., Silvestri L., Levi S., Iolascon A. The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload. Blood 2007, 110:1353-1358.
-
(2007)
Blood
, vol.110
, pp. 1353-1358
-
-
Camaschella, C.1
Campanella, A.2
De, F.L.3
Boschetto, L.4
Merlini, R.5
Silvestri, L.6
Levi, S.7
Iolascon, A.8
-
14
-
-
5444262935
-
The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast
-
Campanella A., Isaya G., O'Neill H.A., Santambrogio P., Cozzi A., Arosio P., Levi S. The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast. Hum. Mol. Genet. 2004, 13:2279-2288.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2279-2288
-
-
Campanella, A.1
Isaya, G.2
O'Neill, H.A.3
Santambrogio, P.4
Cozzi, A.5
Arosio, P.6
Levi, S.7
-
15
-
-
57649243073
-
Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia
-
Campanella A., Rovelli E., Santambrogio P., Cozzi A., Taroni F., Levi S. Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia. Hum. Mol. Genet. 2009, 18:1-11.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1-11
-
-
Campanella, A.1
Rovelli, E.2
Santambrogio, P.3
Cozzi, A.4
Taroni, F.5
Levi, S.6
-
16
-
-
70349464469
-
2-mediated neurotoxicity in rat primary mesencephalic cultures
-
2-mediated neurotoxicity in rat primary mesencephalic cultures. PLoS One 2009, 4:e7095.
-
(2009)
PLoS One
, vol.4
-
-
Cantu, D.1
Schaack, J.2
Patel, M.3
-
17
-
-
34147165135
-
RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload
-
Cavadini P., Biasiotto G., Poli M., Levi S., Verardi R., Zanella I., Derosas M., Ingrassia R., Corrado M., Arosio P. RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload. Blood 2007, 109:3552-3559.
-
(2007)
Blood
, vol.109
, pp. 3552-3559
-
-
Cavadini, P.1
Biasiotto, G.2
Poli, M.3
Levi, S.4
Verardi, R.5
Zanella, I.6
Derosas, M.7
Ingrassia, R.8
Corrado, M.9
Arosio, P.10
-
18
-
-
64049111816
-
Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity
-
Chen H., Lukas T.J., Du N., Suyeoka G., Neufeld A.H. Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity. Invest. Ophthalmol. Vis. Sci. 2009, 50:1895-1902.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 1895-1902
-
-
Chen, H.1
Lukas, T.J.2
Du, N.3
Suyeoka, G.4
Neufeld, A.H.5
-
19
-
-
68049105099
-
Aging of subcortical nuclei: microstructural, mineralization and atrophy modifications measured in vivo using MRI
-
Cherubini A., Peran P., Caltagirone C., Sabatini U., Spalletta G. Aging of subcortical nuclei: microstructural, mineralization and atrophy modifications measured in vivo using MRI. Neuroimage 2009, 48:29-36.
-
(2009)
Neuroimage
, vol.48
, pp. 29-36
-
-
Cherubini, A.1
Peran, P.2
Caltagirone, C.3
Sabatini, U.4
Spalletta, G.5
-
20
-
-
0029092802
-
A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains
-
Connor J.R., Snyder B.S., Arosio P., Loeffler D.A., LeWitt P. A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains. J. Neurochem. 1995, 65:717-724.
-
(1995)
J. Neurochem.
, vol.65
, pp. 717-724
-
-
Connor, J.R.1
Snyder, B.S.2
Arosio, P.3
Loeffler, D.A.4
LeWitt, P.5
-
21
-
-
0032078775
-
Iron accumulation in aging: modulation by dietary restriction
-
Cook C.I., Yu B.P. Iron accumulation in aging: modulation by dietary restriction. Mech. Ageing Dev. 1998, 102:1-13.
-
(1998)
Mech. Ageing Dev.
, vol.102
, pp. 1-13
-
-
Cook, C.I.1
Yu, B.P.2
-
22
-
-
76549093324
-
Iron-binding activity in yeast frataxin entails a trade off with stability in the alpha1/beta1 acidic ridge region
-
Correia A.R., Wang T., Craig E.A., Gomes C.M. Iron-binding activity in yeast frataxin entails a trade off with stability in the alpha1/beta1 acidic ridge region. Biochem. J. 2010, 426:197-203.
-
(2010)
Biochem. J.
, vol.426
, pp. 197-203
-
-
Correia, A.R.1
Wang, T.2
Craig, E.A.3
Gomes, C.M.4
-
23
-
-
0034941118
-
Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease
-
Curtis A.R., Fey C., Morris C.M., Bindoff L.A., Ince P.G., Chinnery P.F., Coulthard A., Jackson M.J., Jackson A.P., McHale D.P., Hay D., Barker W.A., Markham A.F., Bates D., Curtis A., Burn J. Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease. Nat. Genet. 2001, 28:350-354.
-
(2001)
Nat. Genet.
, vol.28
, pp. 350-354
-
-
Curtis, A.R.1
Fey, C.2
Morris, C.M.3
Bindoff, L.A.4
Ince, P.G.5
Chinnery, P.F.6
Coulthard, A.7
Jackson, M.J.8
Jackson, A.P.9
McHale, D.P.10
Hay, D.11
Barker, W.A.12
Markham, A.F.13
Bates, D.14
Curtis, A.15
Burn, J.16
-
24
-
-
20544441525
-
Micronutrient deficiencies and gender: social and economic costs
-
Darnton-Hill I., Webb P., Harvey P.W., Hunt J.M., Dalmiya N., Chopra M., Ball M.J., Bloem M.W., de Benoist B. Micronutrient deficiencies and gender: social and economic costs. Am. J. Clin. Nutr. 2005, 81:1198S-1205S.
-
(2005)
Am. J. Clin. Nutr.
, vol.81
-
-
Darnton-Hill, I.1
Webb, P.2
Harvey, P.W.3
Hunt, J.M.4
Dalmiya, N.5
Chopra, M.6
Ball, M.J.7
Bloem, M.W.8
de Benoist, B.9
-
25
-
-
34249751450
-
Proteome alterations inrat mitochondria caused by aging
-
Dencher N.A., Frenzel M., Reifschneider N.H., Sugawa M., Krause F. Proteome alterations inrat mitochondria caused by aging. Ann. N. Y. Acad. Sci. 2007, 1100:291-298.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1100
, pp. 291-298
-
-
Dencher, N.A.1
Frenzel, M.2
Reifschneider, N.H.3
Sugawa, M.4
Krause, F.5
-
26
-
-
41049106920
-
Flow cytometric estimation of 'labile iron pool' in human white blood cells reveals a positive association with ageing
-
Doulias P.T., Vlachou C., Boudouri C., Kanavaros P., Siamopoulos K.C., Galaris D. Flow cytometric estimation of 'labile iron pool' in human white blood cells reveals a positive association with ageing. Free Radic. Res. 2008, 42:253-259.
-
(2008)
Free Radic. Res.
, vol.42
, pp. 253-259
-
-
Doulias, P.T.1
Vlachou, C.2
Boudouri, C.3
Kanavaros, P.4
Siamopoulos, K.C.5
Galaris, D.6
-
27
-
-
34249104544
-
Oxidative stress and aberrant signaling in aging and cognitive decline
-
Droge W., Schipper H.M. Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 2007, 6:361-370.
-
(2007)
Aging Cell
, vol.6
, pp. 361-370
-
-
Droge, W.1
Schipper, H.M.2
-
28
-
-
0242422377
-
Mitochondrial ferritin: a new player in iron metabolism
-
Drysdale J., Arosio P., Invernizzi R., Cazzola M., Volz A., Corsi B., Biasiotto G., Levi S. Mitochondrial ferritin: a new player in iron metabolism. Blood Cells Mol. Dis. 2002, 29:376-383.
-
(2002)
Blood Cells Mol. Dis.
, vol.29
, pp. 376-383
-
-
Drysdale, J.1
Arosio, P.2
Invernizzi, R.3
Cazzola, M.4
Volz, A.5
Corsi, B.6
Biasiotto, G.7
Levi, S.8
-
29
-
-
34247143301
-
Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture
-
Dunaief J.L. Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture. Invest. Ophthalmol. Vis. Sci. 2006, 47:4660-4664.
-
(2006)
Invest. Ophthalmol. Vis. Sci.
, vol.47
, pp. 4660-4664
-
-
Dunaief, J.L.1
-
31
-
-
37549026885
-
A novel endotoxin-induced pathway: upregulation of heme oxygenase 1, accumulation of free iron, and free iron-mediated mitochondrial dysfunction
-
Duvigneau J.C., Piskernik C., Haindl S., Kloesch B., Hartl R.T., Huttemann M., Lee I., Ebel T., Moldzio R., Gemeiner M., Redl H., Kozlov A.V. A novel endotoxin-induced pathway: upregulation of heme oxygenase 1, accumulation of free iron, and free iron-mediated mitochondrial dysfunction. Lab. Invest. 2008, 88:70-77.
-
(2008)
Lab. Invest.
, vol.88
, pp. 70-77
-
-
Duvigneau, J.C.1
Piskernik, C.2
Haindl, S.3
Kloesch, B.4
Hartl, R.T.5
Huttemann, M.6
Lee, I.7
Ebel, T.8
Moldzio, R.9
Gemeiner, M.10
Redl, H.11
Kozlov, A.V.12
-
32
-
-
0035229641
-
Assessment of mitochondrial membrane potential in situ using single potentiometric dyes and a novel fluorescence resonance energy transfer technique
-
Dykens J.A., Stout A.K. Assessment of mitochondrial membrane potential in situ using single potentiometric dyes and a novel fluorescence resonance energy transfer technique. Methods Cell Biol. 2001, 65:285-309.
-
(2001)
Methods Cell Biol.
, vol.65
, pp. 285-309
-
-
Dykens, J.A.1
Stout, A.K.2
-
34
-
-
0031570288
-
Fluorescence analysis of the labile iron pool of mammalian cells
-
Epsztejn S., Kakhlon O., Glickstein H., Breuer W., Cabantchik I. Fluorescence analysis of the labile iron pool of mammalian cells. Anal. Biochem. 1997, 248:31-40.
-
(1997)
Anal. Biochem.
, vol.248
, pp. 31-40
-
-
Epsztejn, S.1
Kakhlon, O.2
Glickstein, H.3
Breuer, W.4
Cabantchik, I.5
-
35
-
-
31544445770
-
Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity
-
Gakh O., Park S., Liu G., Macomber L., Imlay J.A., Ferreira G.C., Isaya G. Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity. Hum. Mol. Genet. 2006, 15:467-479.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 467-479
-
-
Gakh, O.1
Park, S.2
Liu, G.3
Macomber, L.4
Imlay, J.A.5
Ferreira, G.C.6
Isaya, G.7
-
36
-
-
57649116080
-
Assembly of the iron-binding protein frataxin in Saccharomyces cerevisiae responds to dynamic changes in mitochondrial iron influx and stress level
-
Gakh O., Smith D.Y., Isaya G. Assembly of the iron-binding protein frataxin in Saccharomyces cerevisiae responds to dynamic changes in mitochondrial iron influx and stress level. J. Biol. Chem. 2008, 283:31500-31510.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31500-31510
-
-
Gakh, O.1
Smith, D.Y.2
Isaya, G.3
-
37
-
-
0034809489
-
Induction of oxidative stress by humic acid through increasing intracellular iron: a possible mechanism leading to atherothrombotic vascular disorder in blackfoot disease
-
Gau R.J., Yang H.L., Suen J.L., Lu F.J. Induction of oxidative stress by humic acid through increasing intracellular iron: a possible mechanism leading to atherothrombotic vascular disorder in blackfoot disease. Biochem. Biophys. Res. Commun. 2001, 283:743-749.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.283
, pp. 743-749
-
-
Gau, R.J.1
Yang, H.L.2
Suen, J.L.3
Lu, F.J.4
-
38
-
-
77949421702
-
Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl) piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in symptomatic and neuroprotective therapy for Parkinson's disease
-
Ghosh B., Antonio T., Reith M.E., Dutta A.K. Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl) piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in symptomatic and neuroprotective therapy for Parkinson's disease. J. Med. Chem. 2010, 53:2114-2125.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 2114-2125
-
-
Ghosh, B.1
Antonio, T.2
Reith, M.E.3
Dutta, A.K.4
-
39
-
-
46749101742
-
Deferiprone targets aconitase: implication for Friedreich's ataxia treatment
-
Goncalves S., Paupe V., Dassa E.P., Rustin P. Deferiprone targets aconitase: implication for Friedreich's ataxia treatment. BMC Neurol. 2008, 8:20.
-
(2008)
BMC Neurol.
, vol.8
, pp. 20
-
-
Goncalves, S.1
Paupe, V.2
Dassa, E.P.3
Rustin, P.4
-
40
-
-
30944445397
-
Neurodegeneration with brain iron accumulation
-
Gregory A., Hayflick S.J. Neurodegeneration with brain iron accumulation. Folia Neuropathol. 2005, 43:286-296.
-
(2005)
Folia Neuropathol.
, vol.43
, pp. 286-296
-
-
Gregory, A.1
Hayflick, S.J.2
-
41
-
-
62149099955
-
Clinical and genetic delineation of neurodegeneration with brain iron accumulation
-
Gregory A., Polster B.J., Hayflick S.J. Clinical and genetic delineation of neurodegeneration with brain iron accumulation. J. Med. Genet. 2009, 46:73-80.
-
(2009)
J. Med. Genet.
, vol.46
, pp. 73-80
-
-
Gregory, A.1
Polster, B.J.2
Hayflick, S.J.3
-
42
-
-
68749103147
-
Age-dependent and gender-specific changes in mouse tissue iron by strain
-
Hahn P., Song Y., Ying G.S., He X., Beard J., Dunaief J.L. Age-dependent and gender-specific changes in mouse tissue iron by strain. Exp. Gerontol. 2009, 44:594-600.
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 594-600
-
-
Hahn, P.1
Song, Y.2
Ying, G.S.3
He, X.4
Beard, J.5
Dunaief, J.L.6
-
43
-
-
84961042345
-
The effect of age on the non-haemin iron in the human brain
-
Hallgren B., Sourander P. The effect of age on the non-haemin iron in the human brain. J. Neurochem. 1958, 3:41-51.
-
(1958)
J. Neurochem.
, vol.3
, pp. 41-51
-
-
Hallgren, B.1
Sourander, P.2
-
44
-
-
43849083422
-
Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy
-
Hofer T., Marzetti E., Xu J., Seo A.Y., Gulec S., Knutson M.D., Leeuwenburgh C., Dupont-Versteegden E.E. Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy. Exp. Gerontol. 2008, 43:563-570.
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 563-570
-
-
Hofer, T.1
Marzetti, E.2
Xu, J.3
Seo, A.Y.4
Gulec, S.5
Knutson, M.D.6
Leeuwenburgh, C.7
Dupont-Versteegden, E.E.8
-
45
-
-
20444383489
-
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron
-
Honda K., Smith M.A., Zhu X., Baus D., Merrick W.C., Tartakoff A.M., Hattier T., Harris P.L., Siedlak S.L., Fujioka H., Liu Q., Moreira P.I., Miller F.P., Nunomura A., Shimohama S., Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J. Biol. Chem. 2005, 280:20978-20986.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20978-20986
-
-
Honda, K.1
Smith, M.A.2
Zhu, X.3
Baus, D.4
Merrick, W.C.5
Tartakoff, A.M.6
Hattier, T.7
Harris, P.L.8
Siedlak, S.L.9
Fujioka, H.10
Liu, Q.11
Moreira, P.I.12
Miller, F.P.13
Nunomura, A.14
Shimohama, S.15
Perry, G.16
-
46
-
-
73449091792
-
Yeast frataxin mutants display decreased superoxide dismutase activities crucial to promote protein oxidative damage
-
Irazusta V., Obis E., Moreno-Cermeno A., Cabiscol E., Ros J., Tamarit J. Yeast frataxin mutants display decreased superoxide dismutase activities crucial to promote protein oxidative damage. Free Radic. Biol. Med. 2009, 48:411-420.
-
(2009)
Free Radic. Biol. Med.
, vol.48
, pp. 411-420
-
-
Irazusta, V.1
Obis, E.2
Moreno-Cermeno, A.3
Cabiscol, E.4
Ros, J.5
Tamarit, J.6
-
47
-
-
39149086065
-
Plantaris muscle of aged rats demonstrates iron accumulation and altered expression of iron regulation proteins
-
Jung S.H., DeRuisseau L.R., Kavazis A.N., Deruisseau K.C. Plantaris muscle of aged rats demonstrates iron accumulation and altered expression of iron regulation proteins. Exp. Physiol. 2008, 93:407-414.
-
(2008)
Exp. Physiol.
, vol.93
, pp. 407-414
-
-
Jung, S.H.1
DeRuisseau, L.R.2
Kavazis, A.N.3
Deruisseau, K.C.4
-
48
-
-
0037108199
-
The labile iron pool: characterization, measurement, and participation in cellular processes(1)
-
Kakhlon O., Cabantchik Z.I. The labile iron pool: characterization, measurement, and participation in cellular processes(1). Free Radic. Biol. Med. 2002, 33:1037-1046.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1037-1046
-
-
Kakhlon, O.1
Cabantchik, Z.I.2
-
49
-
-
3042654997
-
Does cellular iron dysregulation play a causative role in Parkinson's disease?
-
Kaur D., Andersen J. Does cellular iron dysregulation play a causative role in Parkinson's disease?. Ageing Res. Rev. 2004, 3:327-343.
-
(2004)
Ageing Res. Rev.
, vol.3
, pp. 327-343
-
-
Kaur, D.1
Andersen, J.2
-
50
-
-
0142152329
-
Iron accumulation during cellular senescence in human fibroblasts in vitro
-
Killilea D.W., Atamna H., Liao C., Ames B.N. Iron accumulation during cellular senescence in human fibroblasts in vitro. Antioxid. Redox Signal. 2003, 5:507-516.
-
(2003)
Antioxid. Redox Signal.
, vol.5
, pp. 507-516
-
-
Killilea, D.W.1
Atamna, H.2
Liao, C.3
Ames, B.N.4
-
51
-
-
3242666078
-
Iron accumulation during cellular senescence
-
Killilea D.W., Wong S.L., Cahaya H.S., Atamna H., Ames B.N. Iron accumulation during cellular senescence. Ann. N. Y. Acad. Sci. 2004, 1019:365-367.
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1019
, pp. 365-367
-
-
Killilea, D.W.1
Wong, S.L.2
Cahaya, H.S.3
Atamna, H.4
Ames, B.N.5
-
52
-
-
56749085451
-
Body iron metabolism and pathophysiology of iron overload
-
Kohgo Y., Ikuta K., Ohtake T., Torimoto Y., Kato J. Body iron metabolism and pathophysiology of iron overload. Int. J. Hematol. 2008, 88:7-15.
-
(2008)
Int. J. Hematol.
, vol.88
, pp. 7-15
-
-
Kohgo, Y.1
Ikuta, K.2
Ohtake, T.3
Torimoto, Y.4
Kato, J.5
-
53
-
-
0026673628
-
Role of iron in oxidative stress in skeletal muscle atrophied by immobilization
-
Kondo H., Miura M., Kodama J., Ahmed S.M., Itokawa Y. Role of iron in oxidative stress in skeletal muscle atrophied by immobilization. Pflugers Arch. 1992, 421:295-297.
-
(1992)
Pflugers Arch.
, vol.421
, pp. 295-297
-
-
Kondo, H.1
Miura, M.2
Kodama, J.3
Ahmed, S.M.4
Itokawa, Y.5
-
54
-
-
0026755419
-
Intracellular free iron in liver tissue and liver homogenate: studies with electron paramagnetic resonance on the formation of paramagnetic complexes with desferal and nitric oxide
-
Kozlov A.V., Yegorov D.Y., Vladimirov Y.A., Azizova O.A. Intracellular free iron in liver tissue and liver homogenate: studies with electron paramagnetic resonance on the formation of paramagnetic complexes with desferal and nitric oxide. Free Radic. Biol. Med. 1992, 13:9-16.
-
(1992)
Free Radic. Biol. Med.
, vol.13
, pp. 9-16
-
-
Kozlov, A.V.1
Yegorov, D.Y.2
Vladimirov, Y.A.3
Azizova, O.A.4
-
55
-
-
33745205646
-
Intralysosomal iron chelation protects against oxidative stress-induced cellular damage
-
Kurz T., Gustafsson B., Brunk U.T. Intralysosomal iron chelation protects against oxidative stress-induced cellular damage. FEBS J. 2006, 273:3106-3117.
-
(2006)
FEBS J.
, vol.273
, pp. 3106-3117
-
-
Kurz, T.1
Gustafsson, B.2
Brunk, U.T.3
-
56
-
-
0033516467
-
Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria
-
Lange H., Kispal G., Lill R. Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria. J. Biol. Chem. 1999, 274:18989-18996.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18989-18996
-
-
Lange, H.1
Kispal, G.2
Lill, R.3
-
57
-
-
72849119992
-
Iron elevations in the aging Parkinsonian brain: a consequence of impaired iron homeostasis?
-
Lee D.W., Andersen J.K. Iron elevations in the aging Parkinsonian brain: a consequence of impaired iron homeostasis?. J. Neurochem. 2010, 112:332-339.
-
(2010)
J. Neurochem.
, vol.112
, pp. 332-339
-
-
Lee, D.W.1
Andersen, J.K.2
-
58
-
-
26944448935
-
Trace metal regulation of neuronal apoptosis: from genes to behavior
-
Levenson C.W. Trace metal regulation of neuronal apoptosis: from genes to behavior. Physiol. Behav. 2005, 86:399-406.
-
(2005)
Physiol. Behav.
, vol.86
, pp. 399-406
-
-
Levenson, C.W.1
-
60
-
-
67349165712
-
The role of iron in mitochondrial function
-
Levi S., Rovida E. The role of iron in mitochondrial function. Biochim. Biophys. Acta 2009, 1790:629-636.
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 629-636
-
-
Levi, S.1
Rovida, E.2
-
61
-
-
34447502384
-
Green tea catechins upregulate superoxide dismutase and catalase in fruit flies
-
Li Y.M., Chan H.Y., Huang Y., Chen Z.Y. Green tea catechins upregulate superoxide dismutase and catalase in fruit flies. Mol. Nutr. Food Res. 2007, 51:546-554.
-
(2007)
Mol. Nutr. Food Res.
, vol.51
, pp. 546-554
-
-
Li, Y.M.1
Chan, H.Y.2
Huang, Y.3
Chen, Z.Y.4
-
62
-
-
58149251841
-
Chelation of mitochondrial iron prevents seizure-induced mitochondrial dysfunction and neuronal injury
-
Liang L.P., Jarrett S.G., Patel M. Chelation of mitochondrial iron prevents seizure-induced mitochondrial dysfunction and neuronal injury. J. Neurosci. 2008, 28:11550-11556.
-
(2008)
J. Neurosci.
, vol.28
, pp. 11550-11556
-
-
Liang, L.P.1
Jarrett, S.G.2
Patel, M.3
-
63
-
-
33746868343
-
Mechanisms of iron-sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes
-
Lill R., Dutkiewicz R., Elsasser H.P., Hausmann A., Netz D.J., Pierik A.J., Stehling O., Urzica E., Muhlenhoff U. Mechanisms of iron-sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes. Biochim. Biophys. Acta 2006, 1763:652-667.
-
(2006)
Biochim. Biophys. Acta
, vol.1763
, pp. 652-667
-
-
Lill, R.1
Dutkiewicz, R.2
Elsasser, H.P.3
Hausmann, A.4
Netz, D.J.5
Pierik, A.J.6
Stehling, O.7
Urzica, E.8
Muhlenhoff, U.9
-
64
-
-
27644526967
-
A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice
-
Lim J.E., Jin O., Bennett C., Morgan K., Wang F., Trenor C.C., Fleming M.D., Andrews N.C. A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nat. Genet. 2005, 37:1270-1273.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1270-1273
-
-
Lim, J.E.1
Jin, O.2
Bennett, C.3
Morgan, K.4
Wang, F.5
Trenor, C.C.6
Fleming, M.D.7
Andrews, N.C.8
-
65
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin M.T., Beal M.F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006, 443:787-795.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
66
-
-
77449089898
-
Nanoparticle and iron chelators as a potential novel Alzheimer therapy
-
Liu G., Men P., Perry G., Smith M.A. Nanoparticle and iron chelators as a potential novel Alzheimer therapy. Methods Mol. Biol. 2010, 610:123-144.
-
(2010)
Methods Mol. Biol.
, vol.610
, pp. 123-144
-
-
Liu, G.1
Men, P.2
Perry, G.3
Smith, M.A.4
-
67
-
-
62649101836
-
Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli
-
Lukinova N., Iacovelli J., Dentchev T., Wolkow N., Hunter A., Amado D., Ying G.S., Sparrow J.R., Dunaief J.L. Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli. Invest. Ophthalmol. Vis. Sci. 2009, 50:1440-1447.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 1440-1447
-
-
Lukinova, N.1
Iacovelli, J.2
Dentchev, T.3
Wolkow, N.4
Hunter, A.5
Amado, D.6
Ying, G.S.7
Sparrow, J.R.8
Dunaief, J.L.9
-
68
-
-
33645581000
-
Chelation and determination of labile iron in primary hepatocytes by pyridinone fluorescent probes
-
Ma Y., de G.H., Liu Z., Hider R.C., Petrat F. Chelation and determination of labile iron in primary hepatocytes by pyridinone fluorescent probes. Biochem. J. 2006, 395:49-55.
-
(2006)
Biochem. J.
, vol.395
, pp. 49-55
-
-
Ma, Y.1
de, G.H.2
Liu, Z.3
Hider, R.C.4
Petrat, F.5
-
69
-
-
69949091187
-
Response to the increase of oxidative stress and mutation of mitochondrial DNA in aging
-
Ma Y.S., Wu S.B., Lee W.Y., Cheng J.S., Wei Y.H. Response to the increase of oxidative stress and mutation of mitochondrial DNA in aging. Biochim. Biophys. Acta 2009, 1790:1021-1029.
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 1021-1029
-
-
Ma, Y.S.1
Wu, S.B.2
Lee, W.Y.3
Cheng, J.S.4
Wei, Y.H.5
-
70
-
-
76749136290
-
Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy
-
Marzetti E., Hwang J.C., Lees H.A., Wohlgemuth S.E., Dupont-Versteegden E.E., Carter C.S., Bernabei R., Leeuwenburgh C. Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy. Biochim. Biophys. Acta 2010, 1800:235-244.
-
(2010)
Biochim. Biophys. Acta
, vol.1800
, pp. 235-244
-
-
Marzetti, E.1
Hwang, J.C.2
Lees, H.A.3
Wohlgemuth, S.E.4
Dupont-Versteegden, E.E.5
Carter, C.S.6
Bernabei, R.7
Leeuwenburgh, C.8
-
71
-
-
65549136627
-
Sarcopenia of aging: underlying cellular mechanisms and protection by calorie restriction
-
Marzetti E., Lees H.A., Wohlgemuth S.E., Leeuwenburgh C. Sarcopenia of aging: underlying cellular mechanisms and protection by calorie restriction. Biofactors 2009, 35:28-35.
-
(2009)
Biofactors
, vol.35
, pp. 28-35
-
-
Marzetti, E.1
Lees, H.A.2
Wohlgemuth, S.E.3
Leeuwenburgh, C.4
-
72
-
-
33845209693
-
Skeletal muscle apoptosis, sarcopenia and frailty at old age
-
Marzetti E., Leeuwenburgh C. Skeletal muscle apoptosis, sarcopenia and frailty at old age. Exp. Gerontol. 2006, 41:1234-1238.
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 1234-1238
-
-
Marzetti, E.1
Leeuwenburgh, C.2
-
73
-
-
0027316214
-
Inhibition of iron absorption prolongs the life span of Drosophila
-
Massie H.R., Aiello V.R., Williams T.R. Inhibition of iron absorption prolongs the life span of Drosophila. Mech. Ageing Dev. 1993, 67:227-237.
-
(1993)
Mech. Ageing Dev.
, vol.67
, pp. 227-237
-
-
Massie, H.R.1
Aiello, V.R.2
Williams, T.R.3
-
74
-
-
33947623671
-
Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders
-
Mattson M.P. Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders. Antioxid. Redox Signal. 2006, 8:1997-2006.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1997-2006
-
-
Mattson, M.P.1
-
75
-
-
0031058837
-
Use of desferrioxamine in the treatment of aceruloplasminemia
-
Miyajima H., Takahashi Y., Kamata T., Shimizu H., Sakai N., Gitlin J.D. Use of desferrioxamine in the treatment of aceruloplasminemia. Ann. Neurol. 1997, 41:404-407.
-
(1997)
Ann. Neurol.
, vol.41
, pp. 404-407
-
-
Miyajima, H.1
Takahashi, Y.2
Kamata, T.3
Shimizu, H.4
Sakai, N.5
Gitlin, J.D.6
-
76
-
-
1842504357
-
The metabolism of neuronal iron and its pathogenic role in neurological disease: review
-
Moos T., Morgan E.H. The metabolism of neuronal iron and its pathogenic role in neurological disease: review. Ann. N. Y. Acad. Sci. 2004, 1012:14-26.
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1012
, pp. 14-26
-
-
Moos, T.1
Morgan, E.H.2
-
77
-
-
0037101845
-
The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins
-
Muhlenhoff U., Richhardt N., Ristow M., Kispal G., Lill R. The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins. Hum. Mol. Genet. 2002, 11:2025-2036.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2025-2036
-
-
Muhlenhoff, U.1
Richhardt, N.2
Ristow, M.3
Kispal, G.4
Lill, R.5
-
78
-
-
33646696625
-
Frataxin, iron-sulfur clusters, heme, ROS, and aging
-
Napoli E., Taroni F., Cortopassi G.A. Frataxin, iron-sulfur clusters, heme, ROS, and aging. Antioxid. Redox Signal. 2006, 8:506-516.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 506-516
-
-
Napoli, E.1
Taroni, F.2
Cortopassi, G.A.3
-
79
-
-
35449004149
-
Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle
-
O'Connell K., Gannon J., Doran P., Ohlendieck K. Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle. Int. J. Mol. Med. 2007, 20:145-153.
-
(2007)
Int. J. Mol. Med.
, vol.20
, pp. 145-153
-
-
O'Connell, K.1
Gannon, J.2
Doran, P.3
Ohlendieck, K.4
-
80
-
-
62549093116
-
The pathogenesis of Friedreich ataxia and the structure and function of frataxin
-
Pandolfo M., Pastore A. The pathogenesis of Friedreich ataxia and the structure and function of frataxin. J. Neurol. 2009, 256(Suppl. 1):9-17.
-
(2009)
J. Neurol.
, vol.256
, Issue.SUPPL. 1
, pp. 9-17
-
-
Pandolfo, M.1
Pastore, A.2
-
81
-
-
70449724600
-
Black tea theaflavins extend the lifespan of fruit flies
-
Peng C., Chan H.Y., Li Y.M., Huang Y., Chen Z.Y. Black tea theaflavins extend the lifespan of fruit flies. Exp. Gerontol. 2009, 44:773-783.
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 773-783
-
-
Peng, C.1
Chan, H.Y.2
Li, Y.M.3
Huang, Y.4
Chen, Z.Y.5
-
82
-
-
67650497965
-
Volume and iron content in basal ganglia and thalamus
-
Peran P., Cherubini A., Luccichenti G., Hagberg G., Demonet J.F., Rascol O., Celsis P., Caltagirone C., Spalletta G., Sabatini U. Volume and iron content in basal ganglia and thalamus. Hum. Brain Mapp. 2009, 30:2667-2675.
-
(2009)
Hum. Brain Mapp.
, vol.30
, pp. 2667-2675
-
-
Peran, P.1
Cherubini, A.2
Luccichenti, G.3
Hagberg, G.4
Demonet, J.F.5
Rascol, O.6
Celsis, P.7
Caltagirone, C.8
Spalletta, G.9
Sabatini, U.10
-
83
-
-
0035874476
-
Subcellular distribution of chelatable iron: a laser scanning microscopic study in isolated hepatocytes and liver endothelial cells
-
Petrat F., de G.H., Rauen U. Subcellular distribution of chelatable iron: a laser scanning microscopic study in isolated hepatocytes and liver endothelial cells. Biochem. J. 2001, 356:61-69.
-
(2001)
Biochem. J.
, vol.356
, pp. 61-69
-
-
Petrat, F.1
de, G.H.2
Rauen, U.3
-
84
-
-
0036249684
-
The chelatable iron pool in living cells: a methodically defined quantity
-
Petrat F., de G.H., Sustmann R., Rauen U. The chelatable iron pool in living cells: a methodically defined quantity. Biol. Chem. 2002, 383:489-502.
-
(2002)
Biol. Chem.
, vol.383
, pp. 489-502
-
-
Petrat, F.1
de, G.H.2
Sustmann, R.3
Rauen, U.4
-
85
-
-
0037083893
-
Selective determination of mitochondrial chelatable iron in viable cells with a new fluorescent sensor
-
Petrat F., Weisheit D., Lensen M., de G.H., Sustmann R., Rauen U. Selective determination of mitochondrial chelatable iron in viable cells with a new fluorescent sensor. Biochem. J. 2002, 362:137-147.
-
(2002)
Biochem. J.
, vol.362
, pp. 137-147
-
-
Petrat, F.1
Weisheit, D.2
Lensen, M.3
de, G.H.4
Sustmann, R.5
Rauen, U.6
-
86
-
-
67349165691
-
MRI estimates of brain iron concentration in normal aging: comparison of field-dependent (FDRI) and phase (SWI) methods
-
Pfefferbaum A., Adalsteinsson E., Rohlfing T., Sullivan E.V. MRI estimates of brain iron concentration in normal aging: comparison of field-dependent (FDRI) and phase (SWI) methods. Neuroimage 2009, 47:493-500.
-
(2009)
Neuroimage
, vol.47
, pp. 493-500
-
-
Pfefferbaum, A.1
Adalsteinsson, E.2
Rohlfing, T.3
Sullivan, E.V.4
-
87
-
-
0142200240
-
Iron as the malignant spirit in successful ageing
-
Polla A.S., Polla L.L., Polla B.S. Iron as the malignant spirit in successful ageing. Ageing Res. Rev. 2003, 2:25-37.
-
(2003)
Ageing Res. Rev.
, vol.2
, pp. 25-37
-
-
Polla, A.S.1
Polla, L.L.2
Polla, B.S.3
-
88
-
-
38149109254
-
Mass spectrometry-based survey of age-associated protein carbonylation in rat brain mitochondria
-
Prokai L., Yan L.J., Vera-Serrano J.L., Stevens S.M., Forster M.J. Mass spectrometry-based survey of age-associated protein carbonylation in rat brain mitochondria. J. Mass Spectrom. 2007, 42:1583-1589.
-
(2007)
J. Mass Spectrom.
, vol.42
, pp. 1583-1589
-
-
Prokai, L.1
Yan, L.J.2
Vera-Serrano, J.L.3
Stevens, S.M.4
Forster, M.J.5
-
89
-
-
34547602992
-
Assessment of chelatable mitochondrial iron by using mitochondrion-selective fluorescent iron indicators with different iron-binding affinities
-
Rauen U., Springer A., Weisheit D., Petrat F., Korth H.G., de G.H., Sustmann R. Assessment of chelatable mitochondrial iron by using mitochondrion-selective fluorescent iron indicators with different iron-binding affinities. Chembiochem 2007, 8:341-352.
-
(2007)
Chembiochem
, vol.8
, pp. 341-352
-
-
Rauen, U.1
Springer, A.2
Weisheit, D.3
Petrat, F.4
Korth, H.G.5
de, G.H.6
Sustmann, R.7
-
90
-
-
35648947912
-
Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans
-
Rea S.L., Ventura N., Johnson T.E. Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans. PLoS Biol. 2007, 5:e259.
-
(2007)
PLoS Biol.
, vol.5
-
-
Rea, S.L.1
Ventura, N.2
Johnson, T.E.3
-
91
-
-
0004652976
-
Dietary factor influencing iron absorption-an overview
-
John Libbey, London, L. Hallberg, N.-G. Asp (Eds.)
-
Rossander-Hulthen L., Hallberg L. Dietary factor influencing iron absorption-an overview. Iron Nutrition in Health and Disease 1996, 105-115. John Libbey, London. L. Hallberg, N.-G. Asp (Eds.).
-
(1996)
Iron Nutrition in Health and Disease
, pp. 105-115
-
-
Rossander-Hulthen, L.1
Hallberg, L.2
-
92
-
-
0027080934
-
Cellular pool of transient ferric iron, chelatable by deferoxamine and distinct from ferritin, that is involved in oxidative cell injury
-
Rothman R.J., Serroni A., Farber J.L. Cellular pool of transient ferric iron, chelatable by deferoxamine and distinct from ferritin, that is involved in oxidative cell injury. Mol. Pharmacol. 1992, 42:703-710.
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 703-710
-
-
Rothman, R.J.1
Serroni, A.2
Farber, J.L.3
-
93
-
-
17144378216
-
Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis
-
Rouault T.A., Tong W.H. Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis. Nat. Rev. Mol. Cell Biol. 2005, 6:345-351.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 345-351
-
-
Rouault, T.A.1
Tong, W.H.2
-
94
-
-
47249142777
-
Iron-sulfur cluster biogenesis and human disease
-
Rouault T.A., Tong W.H. Iron-sulfur cluster biogenesis and human disease. Trends Genet. 2008, 24:398-407.
-
(2008)
Trends Genet.
, vol.24
, pp. 398-407
-
-
Rouault, T.A.1
Tong, W.H.2
-
95
-
-
39749191225
-
Overexpression of frataxin in the mitochondria increases resistance to oxidative stress and extends lifespan in Drosophila
-
Runko A.P., Griswold A.J., Min K.T. Overexpression of frataxin in the mitochondria increases resistance to oxidative stress and extends lifespan in Drosophila. FEBS Lett. 2008, 582:715-719.
-
(2008)
FEBS Lett.
, vol.582
, pp. 715-719
-
-
Runko, A.P.1
Griswold, A.J.2
Min, K.T.3
-
96
-
-
0142134263
-
Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat
-
Saito K., Ishizaka N., Mitani H., Ohno M., Nagai R. Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat. FEBS Lett. 2003, 551:58-62.
-
(2003)
FEBS Lett.
, vol.551
, pp. 58-62
-
-
Saito, K.1
Ishizaka, N.2
Mitani, H.3
Ohno, M.4
Nagai, R.5
-
97
-
-
35548967459
-
Mitochondrial ferritin expression in adult mouse tissues
-
Santambrogio P., Biasiotto G., Sanvito F., Olivieri S., Arosio P., Levi S. Mitochondrial ferritin expression in adult mouse tissues. J. Histochem. Cytochem. 2007, 55:1129-1137.
-
(2007)
J. Histochem. Cytochem.
, vol.55
, pp. 1129-1137
-
-
Santambrogio, P.1
Biasiotto, G.2
Sanvito, F.3
Olivieri, S.4
Arosio, P.5
Levi, S.6
-
98
-
-
0033525924
-
Oxidative phosphorylation at the fin de siecle
-
Saraste M. Oxidative phosphorylation at the fin de siecle. Science 1999, 283:1488-1493.
-
(1999)
Science
, vol.283
, pp. 1488-1493
-
-
Saraste, M.1
-
99
-
-
0029294664
-
Mitochondrial constituents of corpora amylacea and autofluorescent astrocytic inclusions in senescent human brain
-
Schipper H.M., Cisse S. Mitochondrial constituents of corpora amylacea and autofluorescent astrocytic inclusions in senescent human brain. Glia 1995, 14:55-64.
-
(1995)
Glia
, vol.14
, pp. 55-64
-
-
Schipper, H.M.1
Cisse, S.2
-
100
-
-
0032143836
-
Astrocyte mitochondria: a substrate for iron deposition in the aging rat substantia nigra
-
Schipper H.M., Vininsky R., Brull R., Small L., Brawer J.R. Astrocyte mitochondria: a substrate for iron deposition in the aging rat substantia nigra. Exp. Neurol. 1998, 152:188-196.
-
(1998)
Exp. Neurol.
, vol.152
, pp. 188-196
-
-
Schipper, H.M.1
Vininsky, R.2
Brull, R.3
Small, L.4
Brawer, J.R.5
-
101
-
-
62749165889
-
Overexpression of the yeast frataxin homolog (Yfh1): contrasting effects on iron-sulfur cluster assembly, heme synthesis and resistance to oxidative stress
-
Seguin A., Bayot A., Dancis A., Rogowska-Wrzesinska A., Auchere F., Camadro J.M., Bulteau A.L., Lesuisse E. Overexpression of the yeast frataxin homolog (Yfh1): contrasting effects on iron-sulfur cluster assembly, heme synthesis and resistance to oxidative stress. Mitochondrion 2009, 9:130-138.
-
(2009)
Mitochondrion
, vol.9
, pp. 130-138
-
-
Seguin, A.1
Bayot, A.2
Dancis, A.3
Rogowska-Wrzesinska, A.4
Auchere, F.5
Camadro, J.M.6
Bulteau, A.L.7
Lesuisse, E.8
-
102
-
-
33947169223
-
Gene-specific oxidative lesions in aged rat brain detected by polymerase chain reaction inhibition assay
-
Sen T., Jana S., Sreetama S., Chatterjee U., Chakrabarti S. Gene-specific oxidative lesions in aged rat brain detected by polymerase chain reaction inhibition assay. Free Radic. Res. 2007, 41:288-294.
-
(2007)
Free Radic. Res.
, vol.41
, pp. 288-294
-
-
Sen, T.1
Jana, S.2
Sreetama, S.3
Chatterjee, U.4
Chakrabarti, S.5
-
103
-
-
52449121171
-
Mitochondrial iron accumulation with age and functional consequences
-
Seo A.Y., Xu J., Servais S., Hofer T., Marzetti E., Wohlgemuth S.E., Knutson M.D., Chung H.Y., Leeuwenburgh C. Mitochondrial iron accumulation with age and functional consequences. Aging Cell 2008, 7:706-716.
-
(2008)
Aging Cell
, vol.7
, pp. 706-716
-
-
Seo, A.Y.1
Xu, J.2
Servais, S.3
Hofer, T.4
Marzetti, E.5
Wohlgemuth, S.E.6
Knutson, M.D.7
Chung, H.Y.8
Leeuwenburgh, C.9
-
104
-
-
34347375300
-
Direct interorganellar transfer of iron from endosome to mitochondrion
-
Sheftel A.D., Zhang A.S., Brown C., Shirihai O.S., Ponka P. Direct interorganellar transfer of iron from endosome to mitochondrion. Blood 2007, 110:125-132.
-
(2007)
Blood
, vol.110
, pp. 125-132
-
-
Sheftel, A.D.1
Zhang, A.S.2
Brown, C.3
Shirihai, O.S.4
Ponka, P.5
-
105
-
-
0034213588
-
ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation
-
Shirihai O.S., Gregory T., Yu C., Orkin S.H., Weiss M.J. ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. EMBO J. 2000, 19:2492-2502.
-
(2000)
EMBO J.
, vol.19
, pp. 2492-2502
-
-
Shirihai, O.S.1
Gregory, T.2
Yu, C.3
Orkin, S.H.4
Weiss, M.J.5
-
106
-
-
34447520021
-
Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease
-
Simmons D.A., Casale M., Alcon B., Pham N., Narayan N., Lynch G. Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease. Glia 2007, 55:1074-1084.
-
(2007)
Glia
, vol.55
, pp. 1074-1084
-
-
Simmons, D.A.1
Casale, M.2
Alcon, B.3
Pham, N.4
Narayan, N.5
Lynch, G.6
-
107
-
-
22244446427
-
SIH - a novel lipophilic iron chelator - protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death
-
Simunek T., Boer C., Bouwman R.A., Vlasblom R., Versteilen A.M., Sterba M., Gersl V., Hrdina R., Ponka P., de Lange J.J., Paulus W.J., Musters R.J. SIH - a novel lipophilic iron chelator - protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death. J. Mol. Cell Cardiol. 2005, 39:345-354.
-
(2005)
J. Mol. Cell Cardiol.
, vol.39
, pp. 345-354
-
-
Simunek, T.1
Boer, C.2
Bouwman, R.A.3
Vlasblom, R.4
Versteilen, A.M.5
Sterba, M.6
Gersl, V.7
Hrdina, R.8
Ponka, P.9
de Lange, J.J.10
Paulus, W.J.11
Musters, R.J.12
-
108
-
-
0032819392
-
Effect of age and caloric restriction on bleomycin-chelatable and nonheme iron in different tissues of C57BL/6 mice
-
Sohal R.S., Wennberg-Kirch E., Jaiswal K., Kwong L.K., Forster M.J. Effect of age and caloric restriction on bleomycin-chelatable and nonheme iron in different tissues of C57BL/6 mice. Free Radic. Biol. Med. 1999, 27:287-293.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 287-293
-
-
Sohal, R.S.1
Wennberg-Kirch, E.2
Jaiswal, K.3
Kwong, L.K.4
Forster, M.J.5
-
110
-
-
67349180293
-
Iron in arterial plaque: modifiable risk factor for atherosclerosis
-
Sullivan J.L. Iron in arterial plaque: modifiable risk factor for atherosclerosis. Biochim. Biophys. Acta 2009, 1790:718-723.
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 718-723
-
-
Sullivan, J.L.1
-
111
-
-
59149084006
-
Ceruloplasmin in neurodegenerative diseases
-
Texel S.J., Xu X., Harris Z.L. Ceruloplasmin in neurodegenerative diseases. Biochem. Soc. Trans. 2008, 36:1277-1281.
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 1277-1281
-
-
Texel, S.J.1
Xu, X.2
Harris, Z.L.3
-
112
-
-
0027214389
-
MR detection of brain iron
-
Thomas L.O., Boyko O.B., Anthony D.C., Burger P.C. MR detection of brain iron. AJNR Am. J. Neuroradiol. 1993, 14:1043-1048.
-
(1993)
AJNR Am. J. Neuroradiol.
, vol.14
, pp. 1043-1048
-
-
Thomas, L.O.1
Boyko, O.B.2
Anthony, D.C.3
Burger, P.C.4
-
113
-
-
0034331239
-
Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells
-
Tong W.H., Rouault T. Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells. EMBO J. 2000, 19:5692-5700.
-
(2000)
EMBO J.
, vol.19
, pp. 5692-5700
-
-
Tong, W.H.1
Rouault, T.2
-
114
-
-
30744458144
-
Reduction of Caenorhabditis elegans frataxin increases sensitivity to oxidative stress, reduces lifespan, and causes lethality in a mitochondrial complex II mutant
-
Vazquez-Manrique R.P., Gonzalez-Cabo P., Ros S., Aziz H., Baylis H.A., Palau F. Reduction of Caenorhabditis elegans frataxin increases sensitivity to oxidative stress, reduces lifespan, and causes lethality in a mitochondrial complex II mutant. FASEB J. 2006, 20:172-174.
-
(2006)
FASEB J.
, vol.20
, pp. 172-174
-
-
Vazquez-Manrique, R.P.1
Gonzalez-Cabo, P.2
Ros, S.3
Aziz, H.4
Baylis, H.A.5
Palau, F.6
-
115
-
-
67549136242
-
Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect
-
Veatch J.R., McMurray M.A., Nelson Z.W., Gottschling D.E. Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell 2009, 137:1247-1258.
-
(2009)
Cell
, vol.137
, pp. 1247-1258
-
-
Veatch, J.R.1
McMurray, M.A.2
Nelson, Z.W.3
Gottschling, D.E.4
-
116
-
-
22144462536
-
Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans
-
Ventura N., Rea S., Henderson S.T., Condo I., Johnson T.E., Testi R. Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans. Aging Cell 2005, 4:109-112.
-
(2005)
Aging Cell
, vol.4
, pp. 109-112
-
-
Ventura, N.1
Rea, S.2
Henderson, S.T.3
Condo, I.4
Johnson, T.E.5
Testi, R.6
-
117
-
-
47849117134
-
Iron withholding: a defense against disease
-
Weinberg E.D., Miklossy J. Iron withholding: a defense against disease. J. Alzheimers Dis. 2008, 13:451-463.
-
(2008)
J. Alzheimers Dis.
, vol.13
, pp. 451-463
-
-
Weinberg, E.D.1
Miklossy, J.2
-
118
-
-
28644444443
-
Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking
-
White R.A., Boydston L.A., Brookshier T.R., McNulty S.G., Nsumu N.N., Brewer B.P., Blackmore K. Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking. Genomics 2005, 86:668-673.
-
(2005)
Genomics
, vol.86
, pp. 668-673
-
-
White, R.A.1
Boydston, L.A.2
Brookshier, T.R.3
McNulty, S.G.4
Nsumu, N.N.5
Brewer, B.P.6
Blackmore, K.7
-
119
-
-
47749130452
-
The MCK mouse heart model of Friedreich's ataxia: alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation
-
Whitnall M., Rahmanto Y.S., Sutak R., Xu X., Becker E.M., Mikhael M.R., Ponka P., Richardson D.R. The MCK mouse heart model of Friedreich's ataxia: alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:9757-9762.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 9757-9762
-
-
Whitnall, M.1
Rahmanto, Y.S.2
Sutak, R.3
Xu, X.4
Becker, E.M.5
Mikhael, M.R.6
Ponka, P.7
Richardson, D.R.8
-
120
-
-
51449110339
-
Iron accumulation with age, oxidative stress and functional decline
-
Xu J., Knutson M.D., Carter C.S., Leeuwenburgh C. Iron accumulation with age, oxidative stress and functional decline. PLoS One 2008, 3:e2865.
-
(2008)
PLoS One
, vol.3
-
-
Xu, J.1
Knutson, M.D.2
Carter, C.S.3
Leeuwenburgh, C.4
-
121
-
-
77951843593
-
Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts
-
pii: 40372
-
Ye H., Jeong S.Y., Ghosh M.C., Kovtunovych G., Silvestri L., Ortillo D., Uchida N., Tisdale J., Camaschella C., Rouault T.A. Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts. J. Clin. Invest. 2010, pii: 40372. 10.1172/JCI40372.
-
(2010)
J. Clin. Invest.
-
-
Ye, H.1
Jeong, S.Y.2
Ghosh, M.C.3
Kovtunovych, G.4
Silvestri, L.5
Ortillo, D.6
Uchida, N.7
Tisdale, J.8
Camaschella, C.9
Rouault, T.A.10
-
122
-
-
0033941827
-
Association of age, sex, and race with body iron stores in adults: analysis of NHANES III data
-
Zacharski L.R., Ornstein D.L., Woloshin S., Schwartz L.M. Association of age, sex, and race with body iron stores in adults: analysis of NHANES III data. Am. Heart J. 2000, 140:98-104.
-
(2000)
Am. Heart J.
, vol.140
, pp. 98-104
-
-
Zacharski, L.R.1
Ornstein, D.L.2
Woloshin, S.3
Schwartz, L.M.4
-
123
-
-
39149096860
-
The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin
-
Zanella I., Derosas M., Corrado M., Cocco E., Cavadini P., Biasiotto G., Poli M., Verardi R., Arosio P. The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin. Biochim. Biophys. Acta 2008, 1782:90-98.
-
(2008)
Biochim. Biophys. Acta
, vol.1782
, pp. 90-98
-
-
Zanella, I.1
Derosas, M.2
Corrado, M.3
Cocco, E.4
Cavadini, P.5
Biasiotto, G.6
Poli, M.7
Verardi, R.8
Arosio, P.9
-
124
-
-
33947622592
-
Impaired respiration is positively correlated with decreased life span in Caenorhabditis elegans models of Friedreich Ataxia
-
Zarse K., Schulz T.J., Birringer M., Ristow M. Impaired respiration is positively correlated with decreased life span in Caenorhabditis elegans models of Friedreich Ataxia. FASEB J. 2007, 21:1271-1275.
-
(2007)
FASEB J.
, vol.21
, pp. 1271-1275
-
-
Zarse, K.1
Schulz, T.J.2
Birringer, M.3
Ristow, M.4
-
125
-
-
0035197893
-
Recovery of muscles of old rats after hindlimb immobilisation by external fixation is impaired compared with those of young rats
-
Zarzhevsky N., Carmeli E., Fuchs D., Coleman R., Stein H., Reznick A.Z. Recovery of muscles of old rats after hindlimb immobilisation by external fixation is impaired compared with those of young rats. Exp. Gerontol. 2001, 36:125-140.
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 125-140
-
-
Zarzhevsky, N.1
Carmeli, E.2
Fuchs, D.3
Coleman, R.4
Stein, H.5
Reznick, A.Z.6
-
126
-
-
0035103932
-
Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes
-
Zecca L., Gallorini M., Schunemann V., Trautwein A.X., Gerlach M., Riederer P., Vezzoni P., Tampellini D. Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes. J. Neurochem. 2001, 76:1766-1773.
-
(2001)
J. Neurochem.
, vol.76
, pp. 1766-1773
-
-
Zecca, L.1
Gallorini, M.2
Schunemann, V.3
Trautwein, A.X.4
Gerlach, M.5
Riederer, P.6
Vezzoni, P.7
Tampellini, D.8
-
127
-
-
8344265251
-
Iron, brain ageing and neurodegenerative disorders
-
Zecca L., Youdim M.B., Riederer P., Connor J.R., Crichton R.R. Iron, brain ageing and neurodegenerative disorders. Nat. Rev. Neurosci. 2004, 5:863-873.
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 863-873
-
-
Zecca, L.1
Youdim, M.B.2
Riederer, P.3
Connor, J.R.4
Crichton, R.R.5
-
128
-
-
11144226961
-
Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria
-
Zhang A.S., Sheftel A.D., Ponka P. Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria. Blood 2005, 105:368-375.
-
(2005)
Blood
, vol.105
, pp. 368-375
-
-
Zhang, A.S.1
Sheftel, A.D.2
Ponka, P.3
-
129
-
-
0034935036
-
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome
-
Zhou B., Westaway S.K., Levinson B., Johnson M.A., Gitschier J., Hayflick S.J. A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat. Genet. 2001, 28:345-349.
-
(2001)
Nat. Genet.
, vol.28
, pp. 345-349
-
-
Zhou, B.1
Westaway, S.K.2
Levinson, B.3
Johnson, M.A.4
Gitschier, J.5
Hayflick, S.J.6
-
130
-
-
66749149301
-
Mitochondrial ABC proteins in health and disease
-
Zutz A., Gompf S., Schagger H., Tampe R. Mitochondrial ABC proteins in health and disease. Biochim. Biophys. Acta 2009, 1787:681-690.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 681-690
-
-
Zutz, A.1
Gompf, S.2
Schagger, H.3
Tampe, R.4
|