Yeast frataxin mutants display decreased superoxide dismutase activity crucial to promote protein oxidative damage

Free Radical Biology and Medicine

Volumn 48, Issue 3, 2010, Pages 411-420

  Irazusta, Verónica ^a   Obis, Elia ^a   Moreno Cermeño, Armando ^a   Cabiscol, Elisa ^a   Ros, Joaquim ^a   Tamarit, Jordi ^a  

^a UNIVERSITY OF LLEIDA   (Spain)

Author keywords

Frataxin; Free radicals; Friedreich ataxia; Iron overload; Iron toxicity; Metal catalyzed oxidation; Protein carbonylation; Superoxide dismutase; Yeast

Indexed keywords

ADENYLATE KINASE; ALPHA ACTIN; BINDING PROTEIN; CATALASE; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; ELONGATION FACTOR 1ALPHA; FRATAXIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN; IRON; KETOL ACID REDUCTOISOMERASE; MAGNESIUM BINDING PROTEIN; MANGANESE; MANGANESE SUPEROXIDE DISMUTASE; MENADIONE; MITOCHONDRIAL ENZYME; MITOCHONDRIAL PROTEIN; PEROXIREDOXIN; PHOSPHOGLYCERATE KINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PYRUVATE KINASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME INACTIVATION; FRIEDREICH ATAXIA; IRON CHELATION; IRON OVERLOAD; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; YEAST CELL;

COPPER; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION REGULATION, FUNGAL; IRON; IRON-BINDING PROTEINS; MANGANESE; MUTATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEINS; SACCHAROMYCES CEREVISIAE; SUPEROXIDE DISMUTASE;

EID: 73449091792     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.11.010     Document Type: Article

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