메뉴 건너뛰기




Volumn 5, Issue 5, 2003, Pages 507-516

Iron Accumulation During Cellular Senescence in Human Fibroblasts In Vitro

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; HYDROXYLAMINE; IRON; N TERT BUTYLHYDROXYLAMINE; UNCLASSIFIED DRUG;

EID: 0142152329     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/152308603770310158     Document Type: Article
Times cited : (73)

References (50)
  • 1
    • 0035100475 scopus 로고    scopus 로고
    • Cellular transformation by SV40 large T antigen: Interaction with host proteins
    • Ali SH and DeCaprio JA. Cellular transformation by SV40 large T antigen: interaction with host proteins. Semin Cancer Biol 11: 15-23, 2001.
    • (2001) Semin Cancer Biol , vol.11 , pp. 15-23
    • Ali, S.H.1    DeCaprio, J.A.2
  • 3
    • 17344390525 scopus 로고    scopus 로고
    • N-t-Butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts
    • Atamna H, Paler-Martinez A, and Ames BN. N-t-Butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts. J Biol Chem 275: 6741-6748, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 6741-6748
    • Atamna, H.1    Paler-Martinez, A.2    Ames, B.N.3
  • 4
    • 0034806211 scopus 로고    scopus 로고
    • N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro
    • Atamna H, Robinson C, Ingersoll R, Elliott H, and Ames BN. N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro. FASEB J 15: 2196-2204, 2001.
    • (2001) FASEB J , vol.15 , pp. 2196-2204
    • Atamna, H.1    Robinson, C.2    Ingersoll, R.3    Elliott, H.4    Ames, B.N.5
  • 5
    • 0037069320 scopus 로고    scopus 로고
    • Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging
    • Atamna H, Killilea DW, Killilea AN, and Ames BN. Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging. Proc Natl Acad Sci U S A 99: 14807-14812, 2002.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 14807-14812
    • Atamna, H.1    Killilea, D.W.2    Killilea, A.N.3    Ames, B.N.4
  • 6
    • 0037082142 scopus 로고    scopus 로고
    • The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age
    • Atamna H, Walter PB, and Ames BN. The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age. Arch Biochem Biophys 397: 345-353, 2002.
    • (2002) Arch Biochem Biophys , vol.397 , pp. 345-353
    • Atamna, H.1    Walter, P.B.2    Ames, B.N.3
  • 8
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman KB and Ames BN. The free radical theory of aging matures. Physiol Rev 78: 547-581, 1998.
    • (1998) Physiol Rev , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 10
    • 0034531651 scopus 로고    scopus 로고
    • Iron regulatory proteins in pathobiology
    • Cairo G and Pietrangelo A. Iron regulatory proteins in pathobiology. Biochem J352 Pt 2: 241-250, 2000.
    • (2000) Biochem J , vol.352 , Issue.PART 2 , pp. 241-250
    • Cairo, G.1    Pietrangelo, A.2
  • 11
    • 0035827697 scopus 로고    scopus 로고
    • 2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts
    • 2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts. J Biol Chem 276:19738-19745, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 19738-19745
    • Caltagirone, A.1    Weiss, G.2    Pantopoulos, K.3
  • 12
    • 0037238101 scopus 로고    scopus 로고
    • Cellular senescence and apoptosis: How cellular responses might influence aging phenotypes
    • Carnpisi J. Cellular senescence and apoptosis: how cellular responses might influence aging phenotypes. Exp Gerontol 38: 5-11, 2003.
    • (2003) Exp Gerontol , vol.38 , pp. 5-11
    • Carnpisi, J.1
  • 13
    • 15844370375 scopus 로고    scopus 로고
    • SV40 large T antigen transactivates the human cdc2 promoter by inducing a CCAAT box binding factor
    • Chen H, Campisi J, and Padmanabhan R. SV40 large T antigen transactivates the human cdc2 promoter by inducing a CCAAT box binding factor. J Biol Chem 271: 13959-13967, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 13959-13967
    • Chen, H.1    Campisi, J.2    Padmanabhan, R.3
  • 14
    • 0032524563 scopus 로고    scopus 로고
    • 2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication
    • 2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. Biochem J 332 (Pt 1): 43-50, 1998.
    • (1998) Biochem J , vol.332 , Issue.PART 1 , pp. 43-50
    • Chen, Q.M.1    Bartholomew, J.C.2    Campisi, J.3    Acosta, M.4    Reagan, J.D.5    Ames, B.N.6
  • 15
    • 0026590705 scopus 로고
    • Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease
    • Connor JR, Snyder BS, Beard JL, Fine RE, and Mufson EJ. Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease. J Neurosci Res 31: 327-335, 1992.
    • (1992) J Neurosci Res , vol.31 , pp. 327-335
    • Connor, J.R.1    Snyder, B.S.2    Beard, J.L.3    Fine, R.E.4    Mufson, E.J.5
  • 16
    • 0029921312 scopus 로고    scopus 로고
    • Molecular markers of senescence in fibroblast-like cultures
    • Cristofalo VJ and Pignolo RJ. Molecular markers of senescence in fibroblast-like cultures. Exp Gerontol 31: 111-123, 1996.
    • (1996) Exp Gerontol , vol.31 , pp. 111-123
    • Cristofalo, V.J.1    Pignolo, R.J.2
  • 18
    • 0033826764 scopus 로고    scopus 로고
    • Iron regulatory proteins and the molecular control of mammalian iron metabolism
    • Eisenstein RS. Iron regulatory proteins and the molecular control of mammalian iron metabolism. Annu Rev Nutr 20: 627-662, 2000.
    • (2000) Annu Rev Nutr , vol.20 , pp. 627-662
    • Eisenstein, R.S.1
  • 19
  • 21
    • 18644370269 scopus 로고    scopus 로고
    • A newly established neuronal rho-0 cell line highly susceptible to oxidative stress accumulates iron and other metals. Relevance to the origin of metal ion deposits in brains with neurodegenerative disorders
    • Fukuyama R, Nakayama A, Nakase T, Toba H, Mukainaka T, Sakaguchi H, Saiwaki T, Sakurai H, Wada M, and Fushiki S. A newly established neuronal rho-0 cell line highly susceptible to oxidative stress accumulates iron and other metals. Relevance to the origin of metal ion deposits in brains with neurodegenerative disorders. J Biol Chem 277: 41455-41462, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 41455-41462
    • Fukuyama, R.1    Nakayama, A.2    Nakase, T.3    Toba, H.4    Mukainaka, T.5    Sakaguchi, H.6    Saiwaki, T.7    Sakurai, H.8    Wada, M.9    Fushiki, S.10
  • 22
    • 0034571026 scopus 로고    scopus 로고
    • Oxidative stress, aging and the proteasomal system
    • Grune T. Oxidative stress, aging and the proteasomal system. Biogerontology 1: 31-40, 2000.
    • (2000) Biogerontology , vol.1 , pp. 31-40
    • Grune, T.1
  • 23
  • 24
    • 84961042345 scopus 로고
    • The effect of age on the non-haemin iron in the human brain
    • Hallgren B and Sourander P. The effect of age on the non-haemin iron in the human brain. J Neurochem 3: 41-51, 1958.
    • (1958) J Neurochem , vol.3 , pp. 41-51
    • Hallgren, B.1    Sourander, P.2
  • 25
    • 0023284933 scopus 로고
    • Free radicals and metal ions in health and disease
    • Halliwell B. Free radicals and metal ions in health and disease. Proc Nutr Soc 46: 13-26, 1987.
    • (1987) Proc Nutr Soc , vol.46 , pp. 13-26
    • Halliwell, B.1
  • 26
    • 0026034279 scopus 로고
    • Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: An X-ray microanalysis
    • Hirsch EC, Brandel JP, Galle P, Javoy-Agid F, and Agid Y. Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis. J Neurochem 56: 446-451, 1991.
    • (1991) J Neurochem , vol.56 , pp. 446-451
    • Hirsch, E.C.1    Brandel, J.P.2    Galle, P.3    Javoy-Agid, F.4    Agid, Y.5
  • 27
    • 0034832956 scopus 로고    scopus 로고
    • Regulation of cellular senescence by p53
    • Itahana K, Dimri G, and Campisi J. Regulation of cellular senescence by p53. Eur J Biochem 268: 2784-2791, 2001.
    • (2001) Eur J Biochem , vol.268 , pp. 2784-2791
    • Itahana, K.1    Dimri, G.2    Campisi, J.3
  • 28
    • 0037133319 scopus 로고    scopus 로고
    • Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha-lipoic acid
    • Liu J, Killilea DW, and Ames BN. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha-lipoic acid. Proc Natl Acad Sci U S A 99: 1876-1881, 2002.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1876-1881
    • Liu, J.1    Killilea, D.W.2    Ames, B.N.3
  • 29
    • 0028214727 scopus 로고
    • Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein
    • Liu S, Thweatt R, Lumpkin CK Jr, and Goldstein S. Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein. Proc Natl Acad Sci U S A 91: 2186-2190, 1994.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 2186-2190
    • Liu, S.1    Thweatt, R.2    Lumpkin C.K., Jr.3    Goldstein, S.4
  • 30
    • 0021988116 scopus 로고
    • Iron accumulation during development and ageing of Drosophila
    • Massie HR, Aiello VR, and Williams TR. Iron accumulation during development and ageing of Drosophila. Mech Ageing Dev 29: 215-220, 1985.
    • (1985) Mech Ageing Dev , vol.29 , pp. 215-220
    • Massie, H.R.1    Aiello, V.R.2    Williams, T.R.3
  • 31
    • 0027316214 scopus 로고
    • Inhibition of iron absorption prolongs the life span of Drosophila
    • Massie HR, Aiello VR, and Williams TR. Inhibition of iron absorption prolongs the life span of Drosophila. Mech Ageing Dev 67: 227-237, 1993.
    • (1993) Mech Ageing Dev , vol.67 , pp. 227-237
    • Massie, H.R.1    Aiello, V.R.2    Williams, T.R.3
  • 33
    • 0036069457 scopus 로고    scopus 로고
    • An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells
    • Nunez-Millacura C, Tapia V, Munoz P, Maccioni RB, and Nunez MT. An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells. J Neurochem 82: 240-248, 2002.
    • (2002) J Neurochem , vol.82 , pp. 240-248
    • Nunez-Millacura, C.1    Tapia, V.2    Munoz, P.3    Maccioni, R.B.4    Nunez, M.T.5
  • 34
    • 0017619294 scopus 로고
    • Extension of the lifespan of cultured normal human diploid cells by vitamin E: A reevaluation
    • Packer L and Smith JR. Extension of the lifespan of cultured normal human diploid cells by vitamin E: a reevaluation. Proc Natl Acad Sci U S A 74: 1640-1641, 1977.
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 1640-1641
    • Packer, L.1    Smith, J.R.2
  • 35
    • 0029055581 scopus 로고
    • Rapid responses to oxidative stress mediated by iron regulatory protein
    • Pantopoulos K and Hentze MW. Rapid responses to oxidative stress mediated by iron regulatory protein. EMBO J 14:2917-2924, 1995.
    • (1995) EMBO J , vol.14 , pp. 2917-2924
    • Pantopoulos, K.1    Hentze, M.W.2
  • 38
    • 0025748840 scopus 로고
    • Oxidants and antioxidants in proliferative senescence
    • Poot M. Oxidants and antioxidants in proliferative senescence. Mutat Res 256: 177-189, 1991.
    • (1991) Mutat Res , vol.256 , pp. 177-189
    • Poot, M.1
  • 39
    • 0026800818 scopus 로고
    • High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men
    • Salonen JT, Nyyssonen K, Korpela H, Tuomilehto J, Seppanen R, and Salonen R. High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. Circulation 86: 803-811, 1992.
    • (1992) Circulation , vol.86 , pp. 803-811
    • Salonen, J.T.1    Nyyssonen, K.2    Korpela, H.3    Tuomilehto, J.4    Seppanen, R.5    Salonen, R.6
  • 40
    • 0030885482 scopus 로고    scopus 로고
    • Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
    • Smith MA, Harris PL, Sayre LM, and Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci U S A 94: 9866-9868, 1997.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9866-9868
    • Smith, M.A.1    Harris, P.L.2    Sayre, L.M.3    Perry, G.4
  • 41
    • 0022346218 scopus 로고
    • Iron induces oxidative stress and may alter the rate of aging in the housefly, Musca domestica
    • Sohal RS, Allen RG, Farmer KJ, and Newton RK. Iron induces oxidative stress and may alter the rate of aging in the housefly, Musca domestica. Mech Ageing Dev 32: 33-38, 1985.
    • (1985) Mech Ageing Dev , vol.32 , pp. 33-38
    • Sohal, R.S.1    Allen, R.G.2    Farmer, K.J.3    Newton, R.K.4
  • 42
    • 0018848490 scopus 로고
    • Altered accumulation of zinc by aging human fibroblasts in culture
    • Sugarman B and Munro HN. Altered accumulation of zinc by aging human fibroblasts in culture. Life Sci 26: 915-920, 1980.
    • (1980) Life Sci , vol.26 , pp. 915-920
    • Sugarman, B.1    Munro, H.N.2
  • 43
    • 0026806469 scopus 로고
    • Stored iron and ischemic heart disease. Empirical support for a new paradigm
    • Sullivan JL. Stored iron and ischemic heart disease. Empirical support for a new paradigm. Circulation 86: 1036-1037, 1992.
    • (1992) Circulation , vol.86 , pp. 1036-1037
    • Sullivan, J.L.1
  • 44
    • 0033862936 scopus 로고    scopus 로고
    • Regulation of the expression of human ferrochelatase by intracellular iron levels
    • Taketani S, Adachi Y, and Nakahashi Y. Regulation of the expression of human ferrochelatase by intracellular iron levels. Eur J Biochem 267: 4685-4692, 2000.
    • (2000) Eur J Biochem , vol.267 , pp. 4685-4692
    • Taketani, S.1    Adachi, Y.2    Nakahashi, Y.3
  • 45
    • 0002207121 scopus 로고    scopus 로고
    • The role of iron and mitochondria in aging
    • edited by Cadenas E and Packer L. New York: Marcel Dekker, Inc
    • Walter PB, Beckman KB, and Ames BN. The role of iron and mitochondria in aging. In: Understanding the Process of Aging, edited by Cadenas E and Packer L. New York: Marcel Dekker, Inc., 1999, pp. 203-227.
    • (1999) Understanding the Process of Aging , pp. 203-227
    • Walter, P.B.1    Beckman, K.B.2    Ames, B.N.3
  • 48
    • 0032704374 scopus 로고    scopus 로고
    • The role of iron in Parkinson disease and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity
    • Yantiri F and Andersen JK. The role of iron in Parkinson disease and 1-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine toxicity. IUBMB Life 48: 139-141, 1999.
    • (1999) IUBMB Life , vol.48 , pp. 139-141
    • Yantiri, F.1    Andersen, J.K.2
  • 49
    • 0002982378 scopus 로고    scopus 로고
    • Iron
    • edited by Ziegler EE and Filer LJ. Washington, DC: ILSI Press
    • Yip R and Dallman PR. Iron. In: Present Knowledge in Nutrition, edited by Ziegler EE and Filer LJ. Washington, DC: ILSI Press, 1996, pp. 277-292.
    • (1996) Present Knowledge in Nutrition , pp. 277-292
    • Yip, R.1    Dallman, P.R.2
  • 50
    • 0027329926 scopus 로고
    • The role of iron in senescence of dopaminergic neurons in Parkinson's disease
    • Youdim MB and Riederer P. The role of iron in senescence of dopaminergic neurons in Parkinson's disease. J Neural Transm Suppl 40: 57-67, 1993.
    • (1993) J Neural Transm Suppl , vol.40 , pp. 57-67
    • Youdim, M.B.1    Riederer, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.