Iron chelation protects the retinal pigment epithelial cell line ARPE-19 against cell death triggered by diverse stimuli

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 3, 2009, Pages 1440-1447

  Lukinova, Nina ^a   Iacovelli, Jared ^a   Dentchev, Tzvete ^a   Wolkow, Natalie ^a   Hunter, Allan ^a   Amado, Defne ^a   Ying, Gui Shuang ^b   Sparrow, Janet R ^c   Dunaief, Joshua L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Columbia College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SALICYLALDEHYDE; SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE; STAUROSPORINE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; A2E COMPOUND; ALDEHYDE; ANTI FAS MONOCLONAL ANTIBODY; ANTI-FAS MONOCLONAL ANTIBODY; FENTON'S REAGENT; HYDRAZONE DERIVATIVE; IRON; IRON CHELATING AGENT; MONOCLONAL ANTIBODY; PYRIDINIUM DERIVATIVE; RETINOID;

ARTICLE; BLUE LIGHT; CELL DEATH; CELL LINE; CELL PROTECTION; CONTROLLED STUDY; ENZYME RELEASE; HUMAN; HUMAN CELL; IRON CHELATION; PIGMENT EPITHELIUM; PRIORITY JOURNAL; APOPTOSIS; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALDEHYDES; ANTIBODIES, MONOCLONAL; APOPTOSIS; CELL LINE; CELL SURVIVAL; CYTOPROTECTION; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; HYDRAZONES; HYDROGEN PEROXIDE; IRON; IRON CHELATING AGENTS; L-LACTATE DEHYDROGENASE; PYRIDINIUM COMPOUNDS; REACTIVE OXYGEN SPECIES; RETINAL PIGMENT EPITHELIUM; RETINOIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAUROSPORINE;

EID: 62649101836     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2545     Document Type: Article

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