Rats with extended access to cocaine exhibit increased stress reactivity and sensitivity to the anxiolytic-like effects of the mGluR 2/3 agonist LY379268 during abstinence

Neuropsychopharmacology

Volumn 33, Issue 8, 2008, Pages 1818-1826

  Aujla, Harinder ^a   Martin Fardon, Rémi ^a   Weiss, Friedbert ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Abstinence; Cocaine; Defensive burying; Escalation; Metabotropic glutamate; Stress

Indexed keywords

4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; COCAINE; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; INSTRUMENTAL CONDITIONING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; RAT; RELAPSE; RISK ASSESSMENT; STRESS; TRANQUILIZING ACTIVITY; WITHDRAWAL SYNDROME;

AMINO ACIDS; ANIMALS; ANTI-ANXIETY AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; COCAINE-RELATED DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSHOCK; EXCITATORY AMINO ACID AGONISTS; FOOD; MALE; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; REINFORCEMENT (PSYCHOLOGY); STRESS, PSYCHOLOGICAL; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 45149124518     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301588     Document Type: Article

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