Neurobiology of craving, conditioned reward and relapse

Current Opinion in Pharmacology

Volumn 5, Issue 1, 2005, Pages 9-19

  Weiss, Friedbert ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; SUCROSE;

COMPULSION; CONDITIONING; DISEASE PREDISPOSITION; DRUG DEPENDENCE; DRUG TARGETING; DRUG USE; DRUG WITHDRAWAL; EVIDENCE BASED MEDICINE; EVOKED RESPONSE; EXPERIENCE; HUMAN; MEDICAL RESEARCH; MOTIVATION; NERVOUS SYSTEM; NEUROANATOMY; NEUROBIOLOGY; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; RECURRENCE RISK; RELAPSE; REVIEW; REWARD; RISK FACTOR; SIGNAL TRANSDUCTION; STATE DEPENDENT LEARNING; STRESS; WITHDRAWAL SYNDROME;

ANIMALS; BRAIN; CONDITIONING (PSYCHOLOGY); CONDITIONING, CLASSICAL; HUMANS; NEUROBIOLOGY; RECURRENCE; REWARD; SUBSTANCE-RELATED DISORDERS;

EID: 12344279071     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2004.11.001     Document Type: Review

References (94)

1. C.P. O'Brien A.R. Childress R. Ehrman S.J. Robbins Conditioning factors in drug abuse: Can they explain compulsion? J Psychopharmacol 12 1998 15-22
2. R. Sinha How does stress increase risk of drug abuse and relapse? Psychopharmacology (Berl) 158 2001 343-359
3. I.H. Franken Drug craving and addiction: Integrating psychological and neuropsychopharmacological approaches Prog Neuropsychopharmacol Biol Psychiatry 27 2003 563-579
4. J.T. Ingjaldsson J.F. Thayer J.C. Laberg Preattentive processing of alcohol stimuli Scand J Psychol 44 2003 161-165
5. S.T. Tiffany Cognitive concepts of craving Alcohol Res Health 23 1999 215-224
6. J. Altman B.J. Everitt S. Glautier A. Markou D. Nutt R. Oretti G.D. Phillips T.W. Robbins The biological, social and clinical bases of drug addiction: Commentary and debate Psychopharmacology (Berl) 125 1996 285-345
7. S.J. Wilson M.A. Sayette J.A. Fiez Prefrontal responses to drug cues: A neurocognitive analysis Nat Neurosci 7 2004 211-214
8. J. Littleton Can craving be modeled in animals? The relapse prevention perspective Addiction 95 Suppl 2 2000 S83-S90
9. R.E. See Neural substrates of conditioned-cued relapse to drug-seeking behavior Pharmacol Biochem Behav 71 2002 517-529
10. B.J. Everitt A. Dickinson T.W. Robbins The neuropsychological basis of addictive behaviour Brain Res Brain Res Rev 36 2001 129-138
11. P.J. Kenny G.F. Koob A. Markou Conditioned facilitation of brain reward function after repeated cocaine administration Behav Neurosci 117 2003 1103-1107
12. D.C. Drummond Theories of drug craving, ancient and modern Addiction 96 2001 33-46
13. S.T. Tiffany B.L. Carter E.G. Singleton Challenges in the manipulation, assessment and interpretation of craving relevant variables Addiction 95 Suppl 2 2000 S177-S187
14. J.L. Katz S.T. Higgins The validity of the reinstatement model of craving and relapse to drug use Psychopharmacology (Berl) 168 2003 21-30
15. M.R. Daglish D.J. Nutt Brain imaging studies in human addicts Eur Neuropsychopharmacol 13 2003 453-458
16. N.S. Miller R.J. Goldsmith Craving for alcohol and drugs in animals and humans: Biology and behavior J Addict Dis 20 2001 87-104
17. R.Z. Goldstein N.D. Volkow Drug addiction and its underlying neurobiological basis: Neuroimaging evidence for the involvement of the frontal cortex Am J Psychiatry 159 2002 1642-1652
18. R.N. Cardinal J.A. Parkinson J. Hall B.J. Everitt Emotion and motivation: The role of the amygdala, ventral striatum, and prefrontal cortex Neurosci Biobehav Rev 26 2002 321-352
19. Y. Shaham U. Shalev L. Lu H. De Wit J. Stewart The reinstatement model of drug relapse: History, methodology and major findings Psychopharmacology (Berl) 168 2003 3-20
20. B.J. Everitt T.W. Robbins Second-order schedules of drug reinforcement in rats and monkeys: Measurement of reinforcing efficacy and drug-seeking behaviour Psychopharmacology (Berl) 153 2000 17-30
21. P. Di Ciano B.J. Everitt Differential control over drug-seeking behavior by drug-associated conditioned reinforcers and discriminative stimuli predictive of drug availability Behav Neurosci 117 2003 952-960
22. N.E. Goeders D.M. Clampitt Potential role for the hypothalamo-pituitary-adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats Psychopharmacology (Berl) 161 2002 222-232
23. G. Di Chiara Nucleus accumbens shell and core dopamine: Differential role in behavior and addiction Behav Brain Res 137 2002 75-114
24. R.A. Fuchs K.A. Evans M.C. Parker R.E. See Differential involvement of the core and shell subregions of the nucleus accumbens in conditioned cue-induced reinstatement of cocaine seeking in rats Psychopharmacology (Berl) 176 2004 459-465
25. P. Di Ciano B.J. Everitt Direct interactions between the basolateral amygdala and nucleus accumbens core underlie cocaine-seeking behavior by rats J Neurosci 24 2004 7167-7173
26. R. Ito T.W. Robbins B.J. Everitt Differential control over cocaine-seeking behavior by nucleus accumbens core and shell Nat Neurosci 7 2004 389-397
27. R.E. See P.J. Kruzich J.W. Grimm Dopamine, but not glutamate, receptor blockade in the basolateral amygdala attenuates conditioned reward in a rat model of relapse to cocaine-seeking behavior Psychopharmacology (Berl) 154 2001 301-310
28. P. Di Ciano B.J. Everitt Contribution of the ventral tegmental area to cocaine-seeking maintained by a drug-paired conditioned stimulus in rats Eur J Neurosci 19 2004 1661-1667
29. U.E. Ghitza A.T. Fabbricatore V. Prokopenko A.P. Pawlak M.O. West Persistent cue-evoked activity of accumbens neurons after prolonged abstinence from self-administered cocaine J Neurosci 23 2003 7239-7245
30. J. McLaughlin R.E. See Selective inactivation of the dorsomedial prefrontal cortex and the basolateral amygdala attenuates conditioned-cued reinstatement of extinguished cocaine-seeking behavior in rats Psychopharmacology (Berl) 168 2003 57-65
31. R.A. Fuchs K.A. Evans M.P. Parker R.E. See Differential involvement of orbitofrontal cortex subregions in conditioned cue-induced and cocaine-primed reinstatement of cocaine seeking in rats J Neurosci 24 2004 6600-6610
32. Fuchs RA, Evans KA, Ledford CC, Parker MP, Case JM, Mehta RH, See RE: The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats. Neuropsychopharmacology 2004, in press
33. I.A. Yun H.L. Fields Basolateral amygdala lesions impair both cue- and cocaine-induced reinstatement in animals trained on a discriminative stimulus task Neuroscience 121 2003 747-757
34. K.M. Kantak Y. Black E. Valencia K. Green-Jordan H.B. Eichenbaum Dissociable effects of lidocaine inactivation of the rostral and caudal basolateral amygdala on the maintenance and reinstatement of cocaine-seeking behavior in rats J Neurosci 22 2002 1126-1136
35. U.E. Ghitza A.T. Fabbricatore V.F. Prokopenko M.O. West Differences between accumbens core and shell neurons exhibiting phasic firing patterns related to drug-seeking behavior during a discriminative-stimulus task J Neurophysiol 92 2004 1608-1614
36. C.A. Miller J.F. Marshall Altered prelimbic cortex output during cue-elicited drug seeking J Neurosci 24 2004 6889-6897
37. T.R. Franklin P.D. Acton J.A. Maldjian J.D. Gray J.R. Croft C.A. Dackis C.P. O'Brien A.R. Childress Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients Biol Psychiatry 51 2002 134-142
38. G. Schoenbaum M.P. Saddoris S.J. Ramus Y. Shaham B. Setlow Cocaine-experienced rats exhibit learning deficits in a task sensitive to orbitofrontal cortex lesions Eur J Neurosci 19 2004 1997-2002
39. N.D. Volkow J.S. Fowler Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex Cereb Cortex 10 2000 318-325
40. G. Fein V. Di Sclafani D.J. Meyerhoff Prefrontal cortical volume reduction associated with frontal cortex function deficit in 6-week abstinent crack-cocaine dependent men Drug Alcohol Depend 68 2002 87-93
41. A. Bechara A.R. Damasio H. Damasio S.W. Anderson Insensitivity to future consequences following damage to human prefrontal cortex Cognition 50 1994 7-15
42. J.W. Grimm L. Lu T. Hayashi B.T. Hope T.P. Su Y. Shaham Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: Implications for incubation of cocaine craving J Neurosci 23 2003 742-747
43. L. Lu J.W. Grimm J. Dempsey Y. Shaham Cocaine seeking over extended withdrawal periods in rats: Different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months Psychopharmacology (Berl) 176 2004 101-108
44. V. Deroche-Gamonet D. Belin P.V. Piazza Evidence for addiction-like behavior in the rat Science 305 2004 1014-1017
45. R. Ciccocioppo R. Martin-Fardon F. Weiss Stimuli associated with a single cocaine experience elicit long-lasting cocaine-seeking Nat Neurosci 7 2004 495-496
46. P. Di Ciano B.J. Everitt Reinstatement and spontaneous recovery of cocaine-seeking following extinction and different durations of withdrawal Behav Pharmacol 13 2002 397-405
47. J.W. Grimm Y. Shaham B.T. Hope Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats Behav Pharmacol 13 2002 379-388
48. J.W. Grimm B.T. Hope R.A. Wise Y. Shaham Neuroadaptation. incubation of cocaine craving after withdrawal Nature 412 2001 141-142
49. L.J. Vanderschuren B.J. Everitt Drug seeking becomes compulsive after prolonged cocaine self-administration Science 305 2004 1017-1019
50. G.F. Koob S.H. Ahmed B. Boutrel S.A. Chen P.J. Kenny A. Markou L.E. O'Dell L.H. Parsons P.P. Sanna Neurobiological mechanisms in the transition from drug use to drug dependence Neurosci Biobehav Rev 27 2004 739-749
51. D.M. Hutcheson B.J. Everitt T.W. Robbins A. Dickinson The role of withdrawal in heroin addiction: Enhances reward or promotes avoidance? Nat Neurosci 4 2001 943-947
52. X. Liu F. Weiss Additive effect of stress and drug cues on reinstatement of ethanol seeking: Exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms J Neurosci 22 2002 7856-7861
53. X. Liu F. Weiss Reversal of ethanol-seeking behavior by D1 and D2 antagonists in an animal model of relapse: Differences in antagonist potency in previously ethanol-dependent versus nondependent rats J Pharmacol Exp Ther 300 2002 882-889
54. R. Ciccocioppo D. Lin R. Martin-Fardon F. Weiss Reinstatement of ethanol-seeking behavior by drug cues following single versus multiple ethanol intoxication in the rat: Effects of naltrexone Psychopharmacology (Berl) 168 2003 208-215
55. X. Liu F. Weiss Stimulus conditioned to foot-shock stress reinstates alcohol-seeking behavior in an animal model of relapse Psychopharmacology (Berl) 168 2003 184-191
56. M.A. Baptista R. Martin-Fardon F. Weiss Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: Comparison between cocaine and a potent conventional reinforcer J Neurosci 24 2004 4723-4727
57. R. Ciccocioppo D. Economidou A. Fedeli S. Angeletti F. Weiss M. Heilig M. Massi Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats Psychopharmacology (Berl) 172 2004 170-178
58. L. Lu J. Dempsey S.Y. Liu J.M. Bossert Y. Shaham A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal J Neurosci 24 2004 1604-1611
59. G.M. Thomas R.L. Huganir MAPK cascade signaling and synaptic plasticity Nat Rev Neurosci 5 2004 173-183
60. M.E. Wolf LTP may trigger addiction Mol Interv 3 2003 248-252
61. L. Lu J.W. Grimm Y. Shaham B.T. Hope Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats J Neurochem 85 2003 1604-1613
62. C.A. Bolanos E.J. Nestler Neurotrophic mechanisms in drug addiction Neuromolecular Med 5 2004 69-83
63. Y. Li B. Kolb T.E. Robinson The location of persistent amphetamine-induced changes in the density of dendritic spines on medium spiny neurons in the nucleus accumbens and caudate-putamen Neuropsychopharmacology 28 2003 1082-1085
64. T.E. Robinson G. Gorny E. Mitton B. Kolb Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex Synapse 39 2001 257-266
65. T.E. Robinson G. Gorny V.R. Savage B. Kolb Widespread but regionally specific effects of experimenter- versus self-administered morphine on dendritic spines in the nucleus accumbens, hippocampus, and neocortex of adult rats Synapse 46 2002 271-279
66. S.D. Norrholm J.A. Bibb E.J. Nestler C.C. Ouimet J.R. Taylor P. Greengard Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5 Neuroscience 116 2003 19-22
67. E. Valjent J.C. Corvol C. Pages M.J. Besson R. Maldonado J. Caboche Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties J Neurosci 20 2000 8701-8709
68. D.A. Baker K. McFarland R.W. Lake H. Shen X.C. Tang S. Toda P.W. Kalivas Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse Nat Neurosci 6 2003 743-749
69. M.S. Bowers K. McFarland R.W. Lake Y.K. Peterson C.C. Lapish M.L. Gregory S.M. Lanier P.W. Kalivas Activator of G protein signaling 3: A gatekeeper of cocaine sensitization and drug seeking Neuron 42 2004 269-281
70. G. Tanda S.R. Goldberg Cannabinoids: Reward, dependence, and underlying neurochemical mechanisms-a review of recent preclinical data Psychopharmacology (Berl) 169 2003 115-134
71. M. Naassila O. Pierrefiche C. Ledent M. Daoust Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice Neuropharmacology 46 2004 243-253
72. S. Gonzalez P.C. Schmid J. Fernandez-Ruiz R. Krebsbach H.H. Schmid J.A. Ramos Region-dependent changes in endocannabinoid transmission in the brain of morphine-dependent rats Addict Biol 8 2003 159-166
73. T.J. De Vries J.R. Homberg R. Binnekade H. Raaso A.N. Schoffelmeer Cannabinoid modulation of the reinforcing and motivational properties of heroin and heroin-associated cues in rats Psychopharmacology (Berl) 168 2003 164-169
74. A.E. Kelley K.C. Berridge The neuroscience of natural rewards: Relevance to addictive drugs J Neurosci 22 2002 3306-3311
75. R.N. Cardinal B.J. Everitt Neural and psychological mechanisms underlying appetitive learning: Links to drug addiction Curr Opin Neurobiol 14 2004 156-162
76. R.M. Carelli Nucleus accumbens cell firing during goal-directed behaviors for cocaine vs 'natural' reinforcement Physiol Behav 76 2002 379-387
77. M.R. Daglish A. Weinstein A.L. Malizia S. Wilson J.K. Melichar A. Lingford-Hughes J.S. Myles P. Grasby D.J. Nutt Functional connectivity analysis of the neural circuits of opiate craving: 'more' rather than 'different'? Neuroimage 20 2003 1964-1970
78. G.F. Koob M. Le Moal Drug addiction, dysregulation of reward, and allostasis Neuropsychopharmacology 24 2001 97-129
79. S.H. Ahmed P.J. Kenny G.F. Koob A. Markou Neurobiological evidence for hedonic allostasis associated with escalating cocaine use Nat Neurosci 5 2002 625-626
80. W. Tang M. Wesley W.M. Freeman B. Liang S.E. Hemby Alterations in ionotropic glutamate receptor subunits during binge cocaine self-administration and withdrawal in rats J Neurochem 89 2004 1021-1033
81. R.J. DiLeone D. Georgescu E.J. Nestler Lateral hypothalamic neuropeptides in reward and drug addiction Life Sci 73 2003 759-768
82. L. Lu J.D. Shepard F.S. Hall Y. Shaham Effect of environmental stressors on opiate and psychostimulant reinforcement, reinstatement and discrimination in rats: A review Neurosci Biobehav Rev 27 2003 457-491
83. A. Le Y. Shaham Neurobiology of relapse to alcohol in rats Pharmacol Ther 94 2002 137-156
84. N.E. Goeders The impact of stress on addiction Eur Neuropsychopharmacol 13 2003 435-441
85. R.W. Foltin M. Haney Conditioned effects of environmental stimuli paired with smoked cocaine in humans Psychopharmacology (Berl) 149 2000 24-33
86. R. Sinha M. Talih R. Malison N. Cooney G.M. Anderson M.J. Kreek Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states Psychopharmacology (Berl) 170 2003 62-72
87. N. Capriles D. Rodaros R.E. Sorge J. Stewart A role for the prefrontal cortex in stress- and cocaine-induced reinstatement of cocaine seeking in rats Psychopharmacology (Berl) 168 2003 66-74
88. S. Scaccianoce F. Matrisciano P. Del Bianco A. Caricasole V. Di Giorgi Gerevini I. Cappuccio D. Melchiorri G. Battaglia F. Nicoletti Endogenous activation of group-II metabotropic glutamate receptors inhibits the hypothalamic-pituitary-adrenocortical axis Neuropharmacology 44 2003 555-561
89. A.M. Linden S.J. Greene M. Bergeron D.D. Schoepp Anxiolytic activity of the mGlu2/3 receptor agonist LY354740 on the elevated plus maze is associated with the suppression of stress-induced c-Fos in the hippocampus and increases in c-Fos induction in several other stress-sensitive brain regions Neuropsychopharmacology 29 2004 502-513
90. C.J. Swanson K.W. Perry D.D. Schoepp The mGlu2/3 receptor agonist, LY354740, blocks immobilization-induced increases in noradrenaline and dopamine release in the rat medial prefrontal cortex J Neurochem 88 2004 194-202
91. R. Ciccocioppo A. Fedeli D. Economidou F. Policani F. Weiss M. Massi The bed nucleus is a neuroanatomical substrate for the anorectic effect of corticotropin-releasing factor and for its reversal by nociceptin/orphanin FQ J Neurosci 23 2003 9445-9451
92. G.R. Valdez E.P. Zorrilla A.J. Roberts G.F. Koob Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence Alcohol 29 2003 55-60
93. K.M. Kantak Y. Black E. Valencia K. Green-Jordan H.B. Eichenbaum Stimulus-response functions of the lateral dorsal striatum and regulation of behavior studied in a cocaine maintenance/cue reinstatement model in rats Psychopharmacology (Berl) 161 2002 278-287
94. Bossert JM, Liu SY, Lu L, Shaham Y: A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking. J Neurosci 2004, 24 in press