Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2

Molecular Pharmacology

Volumn 64, Issue 4, 2003, Pages 798-810

  Schaffhauser, Hervé ^a   Rowe, Blake A ^a   Morales, Sylvia ^a   Chavez Noriega, Laura E ^a   Yin, Ruoyuan ^a   Jachec, Christine ^a   Rao, Sara P ^a   Bain, Gretchen ^a   Pinkerton, Anthony B ^a   Vernier, Jean Michel ^a   Bristow, Linda J ^a   Varney, Mark A ^a   Daggett, Lorrie P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; G PROTEIN COUPLED RECEPTOR; GLUTAMATE RECEPTOR; LY 487379; METABOTROPIC RECEPTOR; N [4 (2 METHOXYPHENOXY)PHENYL] N (2,2,2 TRIFLUROETHYLSULFONYL)PYRID 3 YLMETHYLAMINE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BRAIN SLICE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; DOSE RESPONSE; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BINDING SITES; CALCIUM; CELL MEMBRANE; CEREBRAL CORTEX; CHO CELLS; CRICETINAE; CYCLOPROPANES; DENTATE GYRUS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HIPPOCAMPUS; HUMANS; MOLECULAR SEQUENCE DATA; PERFORANT PATHWAY; PROTEIN STRUCTURE, TERTIARY; PYRIDINES; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; SEQUENCE HOMOLOGY, AMINO ACID; SULFONAMIDES; TRITIUM; XANTHENES;

EID: 0141569348     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.4.798     Document Type: Article

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