-
1
-
-
0032547380
-
Progress in understanding the molecular pathogenesis of human lung cancer
-
Sekido, Y., Fong, K.M., and Minna, J.D. Progress in understanding the molecular pathogenesis of human lung cancer. Biochem Biophys Acta 1998; 1378: F21-F59.
-
(1998)
Biochem Biophys Acta
, vol.1378
, pp. F21-F59
-
-
Sekido, Y.1
Fong, K.M.2
Minna, J.D.3
-
2
-
-
0030738592
-
The interaction of Ras with GTPase-activating proteins
-
Wittinghofer, A., Scheffzek, K., and Ahmadian, M.R. The interaction of Ras with GTPase-activating proteins. FEBS Lett 1997; 410: 63–67.
-
(1997)
FEBS Lett
, vol.410
, pp. 63-67
-
-
Wittinghofer, A.1
Scheffzek, K.2
Ahmadian, M.R.3
-
4
-
-
0031038137
-
Bax suppresses tumorigenesis and stimulates apoptosis in vivo
-
Yin, C., Knudson, C.M., Korsmeyer, S.J., and Van Dyke, T. Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature 1997; 385: 637–640.
-
(1997)
Nature
, vol.385
, pp. 637-640
-
-
Yin, C.1
Knudson, C.M.2
Korsmeyer, S.J.3
Van Dyke, T.4
-
5
-
-
11944271246
-
P53 and chromosome 3 abnormalities, characteristic of malignant lung tumours, are detectable in preinvasive lesions of the bronchus
-
Sundaresan, V., Ganly, P., Hasleton, P., Rudd, R., Sinha, G., Bleehen, N.M., and Rabbitts, P. p53 and chromosome 3 abnormalities, characteristic of malignant lung tumours, are detectable in preinvasive lesions of the bronchus. Oncogene 1992; 7: 1989–1997.
-
(1992)
Oncogene
, vol.7
, pp. 1989-1997
-
-
Sundaresan, V.1
Ganly, P.2
Hasleton, P.3
Rudd, R.4
Sinha, G.5
Bleehen, N.M.6
Rabbitts, P.7
-
6
-
-
0029559378
-
Sequential molecular genetic changes in lung cancer development
-
Chung, G.T., Sundaresan, V., Hasleton, P., Rudd, R., Taylor, R., and Rabbitts, P.H. Sequential molecular genetic changes in lung cancer development. Oncogene 1995; 11: 2591–2598.
-
(1995)
Oncogene
, vol.11
, pp. 2591-2598
-
-
Chung, G.T.1
Sundaresan, V.2
Hasleton, P.3
Rudd, R.4
Taylor, R.5
Rabbitts, P.H.6
-
7
-
-
0029653451
-
Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma
-
Hung, J., Kishimoto, Y., Sugio, K., Virmani, A., Mclntire, D.D., Minna, J.D., and Gazdar, A.F. Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma. JAMA 1995; 273: 558–563.
-
(1995)
JAMA
, vol.273
, pp. 558-563
-
-
Hung, J.1
Kishimoto, Y.2
Sugio, K.3
Virmani, A.4
McLntire, D.D.5
Minna, J.D.6
Gazdar, A.F.7
-
8
-
-
0029082427
-
Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lung cancers
-
Kishimoto, Y., Sugio, K., Hung, J.Y., Virmani, A.K., Mclntire, D.D., Minna, J.D., and Gazdar, A.F. Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lung cancers. J Natl Cancer Inst 1995; 87: 1224–1229.
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 1224-1229
-
-
Kishimoto, Y.1
Sugio, K.2
Hung, J.Y.3
Virmani, A.K.4
McLntire, D.D.5
Minna, J.D.6
Gazdar, A.F.7
-
9
-
-
0027984549
-
K-ras mutations are a relatively late event in the pathogenesis of lung carcinomas
-
Sugio, K., Kishimoto, Y., Virmani, A.K., Hung, J.Y., and Gazdar, A.F. K-ras mutations are a relatively late event in the pathogenesis of lung carcinomas. Cancer Res 1994; 54: 5811–5815.
-
(1994)
Cancer Res
, vol.54
, pp. 5811-5815
-
-
Sugio, K.1
Kishimoto, Y.2
Virmani, A.K.3
Hung, J.Y.4
Gazdar, A.F.5
-
10
-
-
0031886443
-
K-ras point mutation occurs in the early stage of carcinogenesis in lung cancer
-
Sagawa, M., Saito, Y., Fujimura, S., and Linnoila, R.I. K-ras point mutation occurs in the early stage of carcinogenesis in lung cancer. Br J Cancer 1998; 77: 720–723.
-
(1998)
Br J Cancer
, vol.77
, pp. 720-723
-
-
Sagawa, M.1
Saito, Y.2
Fujimura, S.3
Linnoila, R.I.4
-
12
-
-
9044221762
-
Detection of K-ras mutations in lung carcinogenesis: Relationship to prognosis
-
Keohavong, P., DeMichele, M.A., Melacrinos, A.C., Landreneau, R.J., Weyant, R.J., and Siegfried, J.M. Detection of K-ras mutations in lung carcinogenesis: relationship to prognosis. Clin Cancer Res 1996; 2: 411–418.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 411-418
-
-
Keohavong, P.1
DeMichele, M.A.2
Melacrinos, A.C.3
Landreneau, R.J.4
Weyant, R.J.5
Siegfried, J.M.6
-
13
-
-
0028361705
-
C-K-ras and p53 mutations occur very early in adenocarcinoma of the lung
-
Li, Z.H., Zheng, J., Weiss, L.M., and Shibata, D. c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung. Am J Pathol 1994; 144: 303–309.
-
(1994)
Am J Pathol
, vol.144
, pp. 303-309
-
-
Li, Z.H.1
Zheng, J.2
Weiss, L.M.3
Shibata, D.4
-
14
-
-
0030918575
-
The pattern of K-ras mutation in pulmonary adenocarcinoma defines a new pathway of tumour development in the human lung
-
Cooper, C.A., Carey, F.A., Bubb, V.J., Lamb, D., Kerr, K.M., and Wyllie, A.H. The pattern of K-ras mutation in pulmonary adenocarcinoma defines a new pathway of tumour development in the human lung. J Pathol 1997; 181: 401–404.
-
(1997)
J Pathol
, vol.181
, pp. 401-404
-
-
Cooper, C.A.1
Carey, F.A.2
Bubb, V.J.3
Lamb, D.4
Kerr, K.M.5
Wyllie, A.H.6
-
15
-
-
0029933372
-
K-ras oncogene activation in atypical alveolar hyperplasias of the human lung
-
Westra, W.H., Baas, I.O., Hruban, R.H., Askin, F.B., Wilson, K., Offerhaus, G.J., and Slebos, RJ. K-ras oncogene activation in atypical alveolar hyperplasias of the human lung. Cancer Res 1996; 56: 2224–2228.
-
(1996)
Cancer Res
, vol.56
, pp. 2224-2228
-
-
Westra, W.H.1
Baas, I.O.2
Hruban, R.H.3
Askin, F.B.4
Wilson, K.5
Offerhaus, G.J.6
Slebos, R.J.7
-
16
-
-
78651056338
-
Field cancerization in oral stratified squamous epithelium—clinical implications of multicentric origin
-
Slaughter, D.P., Southwick, H.W., and Smejkal, W. “Field cancerization” in oral stratified squamous epithelium—clinical implications of multicentric origin. Cancer 1953; 6: 963–968.
-
(1953)
Cancer
, vol.6
, pp. 963-968
-
-
Slaughter, D.P.1
Southwick, H.W.2
Smejkal, W.3
-
17
-
-
1842359538
-
Mice: Proceedings of an EPA workshop on their use in toxicological testing
-
Published in
-
SENCAR. Mice: Proceedings of an EPA workshop on their use in toxicological testing. Published in, Environ Health Perspect 1986; 68: 3–151.
-
(1986)
Environ Health Perspect
, vol.68
, pp. 3-151
-
-
-
19
-
-
0032578039
-
Epithelial carcinogenesis in the mouse: Correlating the genetics and the biology
-
Frame, S., Crombie, R., Liddell, J., Stuart, D., Linardopoulos, S., Nagase, H., Portella, G., Brown, K., Street, A., Akhurst, R., and Balmain, A. Epithelial carcinogenesis in the mouse: correlating the genetics and the biology. Philos Trans R Soc Lond B Biol Sci 1998; 353: 839–845.
-
(1998)
Philos Trans R Soc Lond B Biol Sci
, vol.353
, pp. 839-845
-
-
Frame, S.1
Crombie, R.2
Liddell, J.3
Stuart, D.4
Linardopoulos, S.5
Nagase, H.6
Portella, G.7
Brown, K.8
Street, A.9
Akhurst, R.10
Balmain, A.11
-
20
-
-
0029782220
-
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasha, v-fos, or human transforming growth factor α
-
Ha, v-fos, or human transforming growth factor α. Cancer Res 1996; 56: 4413–4423.
-
(1996)
Cancer Res
, vol.56
, pp. 4413-4423
-
-
Greenhalgh, D.A.1
Wang, X.-J.2
Donehower, L.A.3
Roop, D.R.4
-
21
-
-
0028143668
-
Role of oncogenes and tumor suppressor genes in multistage carcinogenesis
-
Yuspa, S.H., Dlugosz, A.A., Cheng, C.K., Denning, M.F., Tennenbaum, T., Glick, A.B., and Weinberg, W.C. Role of oncogenes and tumor suppressor genes in multistage carcinogenesis. J Invest Dermatol 1994; 103: 90S-95S.
-
(1994)
J Invest Dermatol
, vol.103
, pp. 90S-95S
-
-
Yuspa, S.H.1
Dlugosz, A.A.2
Cheng, C.K.3
Denning, M.F.4
Tennenbaum, T.5
Glick, A.B.6
Weinberg, W.C.7
-
22
-
-
0026723607
-
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors
-
Nelson, M.A., Futscher, B.W., Kinsella, T., Wymer, J., and Bowden, G.T. Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors. Proc Natl Acad Sci USA 1992; 89: 6398–6402.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6398-6402
-
-
Nelson, M.A.1
Futscher, B.W.2
Kinsella, T.3
Wymer, J.4
Bowden, G.T.5
-
24
-
-
0011493380
-
Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons
-
Bizub, D., Wood, A.W., and Skalka, A.M. Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons. Proc Natl Acad Sci USA 1986; 83: 6048–6052.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6048-6052
-
-
Bizub, D.1
Wood, A.W.2
Skalka, A.M.3
-
25
-
-
0022458856
-
V-ras genes from harvey and BALB murine sarcoma viruses can act as initiators of two stage mouse skin carcinogenesis
-
Brown, K., Quintanilla, M., Ramsden, M., Kerr, I.B., Young, S., and Balmain, A. v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two stage mouse skin carcinogenesis. Cell 1986; 46: 447–456.
-
(1986)
Cell
, vol.46
, pp. 447-456
-
-
Brown, K.1
Quintanilla, M.2
Ramsden, M.3
Kerr, I.B.4
Young, S.5
Balmain, A.6
-
26
-
-
0022527161
-
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
-
Quintanilla, M., Brown, K., Ramsden, M., and Balmain, A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 1986; 322: 78–80.
-
(1986)
Nature
, vol.322
, pp. 78-80
-
-
Quintanilla, M.1
Brown, K.2
Ramsden, M.3
Balmain, A.4
-
27
-
-
0022977903
-
An activated harvey ras oncogene produces benign tumours on mouse epidermal tissue
-
Roop, D.R., Lowy, D.R., Tambourin, P.E., Strickland, J., Harper, J.R., Balaschak, M., Spangler, E.F., and Yuspa, S.H. An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature 1986; 323: 822–824.
-
(1986)
Nature
, vol.323
, pp. 822-824
-
-
Roop, D.R.1
Lowy, D.R.2
Tambourin, P.E.3
Strickland, J.4
Harper, J.R.5
Balaschak, M.6
Spangler, E.F.7
Yuspa, S.H.8
-
28
-
-
0020586334
-
Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming harvey ras oncogene
-
Balmain, A. and Pragnell, I.B. Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey ras oncogene. Nature 1983; 303: 72–74.
-
(1983)
Nature
, vol.303
, pp. 72-74
-
-
Balmain, A.1
Pragnell, I.B.2
-
29
-
-
0021042222
-
Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: Contrasting effects of viruses and chemicals
-
Yuspa, S.H., Vass, W., and Scolnick, E. Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: contrasting effects of viruses and chemicals. Cancer Res 1983; 43: 6021–6030.
-
(1983)
Cancer Res
, vol.43
, pp. 6021-6030
-
-
Yuspa, S.H.1
Vass, W.2
Scolnick, E.3
-
30
-
-
0031966274
-
The traditional toxicologic paradigm is correct: Dose influences mechanism
-
Goodman, J.I. The traditional toxicologic paradigm is correct: dose influences mechanism. Environ Health Perspect 1998; 106: 285–288.
-
(1998)
Environ Health Perspect
, vol.106
, pp. 285-288
-
-
Goodman, J.I.1
-
31
-
-
0032578509
-
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
-
Belinsky, S.A., Nikula, K.J., Palmisano, W.A., Michels, R., Saccomanno, G., Gabrielson, E., Baylin, S.B., and Herman, J.G. Aberrant methylation of pl6(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci USA 1998; 95: 11891–11896.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11891-11896
-
-
Belinsky, S.A.1
Nikula, K.J.2
Palmisano, W.A.3
Michels, R.4
Saccomanno, G.5
Gabrielson, E.6
Baylin, S.B.7
Herman, J.G.8
-
32
-
-
0031594951
-
Coincident alterations of p16lNK4A/CDKN2 and other genes in human lung cancer cell lines
-
Fujishita, T., Mizushima, Y., Kashii, T., and Kobayashi, M. Coincident alterations of p16lNK4A/CDKN2 and other genes in human lung cancer cell lines. Anticancer Res 1998; 18: 1537–1542.
-
(1998)
Anticancer Res
, vol.18
, pp. 1537-1542
-
-
Fujishita, T.1
Mizushima, Y.2
Kashii, T.3
Kobayashi, M.4
-
33
-
-
0029058309
-
Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in Tg
-
AC transgenic mouse skin
-
Owens, D.M., Spalding, J.W., Tennant, R.W., and Smart, R.C. Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in Tg. AC transgenic mouse skin. Cancer Res 1995; 55: 3171–3178.
-
(1995)
Cancer Res
, vol.55
, pp. 3171-3178
-
-
Owens, D.M.1
Spalding, J.W.2
Tennant, R.W.3
Smart, R.C.4
-
34
-
-
0032821287
-
A multihit, multistage model of chemical carcinogenesis
-
Owens, D.M., Wei, S.-J.C., and Smart, R.C. A multihit, multistage model of chemical carcinogenesis. Carcinogenesis 1999; 20: 1837–1844.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1837-1844
-
-
Owens, D.M.1
Wei, S.-J.C.2
Smart, R.C.3
-
35
-
-
75949142944
-
Some biological aspects of skin carcinogenesis
-
Boutwell, R.K. Some biological aspects of skin carcinogenesis. Prog Exp Tumor Res 1964; 19: 207–250.
-
(1964)
Prog Exp Tumor Res
, vol.19
, pp. 207-250
-
-
Boutwell, R.K.1
-
36
-
-
0014353314
-
Co-carcinogenic principles from the seed oil of croton tiglium and from other euphorbiaceae
-
Hecker, E. Co-carcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae. Cancer Res 1968; 28: 2338–2349.
-
(1968)
Cancer Res
, vol.28
, pp. 2338-2349
-
-
Hecker, E.1
-
37
-
-
0020660896
-
Tumor promotion by phorbol esters in skin: Evidence for a memory effect
-
Furstenberger, G., Sorg, B., and Marks, F. Tumor promotion by phorbol esters in skin: evidence for a memory effect. Science 1983; 220: 89–91.
-
(1983)
Science
, vol.220
, pp. 89-91
-
-
Furstenberger, G.1
Sorg, B.2
Marks, F.3
-
38
-
-
0022343002
-
Partial inversion of multistage tumorigenesis in the skin of NMRI mice
-
Furstenberger, G., Kinzel, V., Schwarz, M., and Marks, F. Partial inversion of multistage tumorigenesis in the skin of NMRI mice. Science 1985; 230: 76–78.
-
(1985)
Science
, vol.230
, pp. 76-78
-
-
Furstenberger, G.1
Kinzel, V.2
Schwarz, M.3
Marks, F.4
-
39
-
-
0017716766
-
Effect of tumor-promoting agents on mutation frequencies in cultured V79 chinese hamster cells
-
Lankas, G.R., Baxter, C.S., and Christian, R.T. Effect of tumor-promoting agents on mutation frequencies in cultured V79 Chinese hamster cells. Mutat Res 1977; 45: 153–156.
-
(1977)
Mutat Res
, vol.45
, pp. 153-156
-
-
Lankas, G.R.1
Baxter, C.S.2
Christian, R.T.3
-
40
-
-
0020055891
-
DNA strand breakage in human leukocytes exposed to a tumor promoter, phorbol myristate acetate
-
Birnboim, H.C. DNA strand breakage in human leukocytes exposed to a tumor promoter, phorbol myristate acetate. Science 1982; 215: 1247–1249.
-
(1982)
Science
, vol.215
, pp. 1247-1249
-
-
Birnboim, H.C.1
-
41
-
-
0022372944
-
Tumor promoter 12-O-tetrade-canolyphorbol-13-acetate (TPA)-induced chromosome aberrations in mouse keratinocyte cell lines: A possible genetic mechanism of tumor promotion
-
Dzarlieva-Petrusevska, R.T. and Fusenig, N.E. Tumor promoter 12-O-tetrade-canolyphorbol-13-acetate (TPA)-induced chromosome aberrations in mouse keratinocyte cell lines: a possible genetic mechanism of tumor promotion. Carcinogenesis 1985; 6: 1447–1456.
-
(1985)
Carcinogenesis
, vol.6
, pp. 1447-1456
-
-
Dzarlieva-Petrusevska, R.T.1
Fusenig, N.E.2
-
42
-
-
0023899639
-
Cytogenetic effects caused by phorbol ester tumor promotion in primary mouse keratinocyte cultures: Correlation with the convertogenic activity of TPA in multistage skin carcinogenesis
-
Petrusevska, R.T., Furstenberger, G., Marks, F., and Fusenig, N.E. Cytogenetic effects caused by phorbol ester tumor promotion in primary mouse keratinocyte cultures: correlation with the convertogenic activity of TPA in multistage skin carcinogenesis. Carcinogenesis 1988; 9: 1207–1215.
-
(1988)
Carcinogenesis
, vol.9
, pp. 1207-1215
-
-
Petrusevska, R.T.1
Furstenberger, G.2
Marks, F.3
Fusenig, N.E.4
-
43
-
-
0024521987
-
Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: Correlation between chromosome damage and conversion (stage 1 of tumor promotion) in vivo
-
Furstenberger, G., Schurich, B., Kaina, B., Petrusevska, R.T., Fusenig, N.E., and Marks, F. Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: correlation between chromosome damage and conversion (stage 1 of tumor promotion) in vivo. Carcinogenesis 1989; 10: 749–752.
-
(1989)
Carcinogenesis
, vol.10
, pp. 749-752
-
-
Furstenberger, G.1
Schurich, B.2
Kaina, B.3
Petrusevska, R.T.4
Fusenig, N.E.5
Marks, F.6
-
44
-
-
0027506021
-
Induction and inhibition of tumor progression
-
Warren, B.S., Naylor, M.F., Winberg, L.D., Yoshimi, N., Volpe, J.P., Gimenez-Conti, I., and Slaga, TJ. Induction and inhibition of tumor progression. Proc Soc Exp Biol Med 1993; 202: 9–15.
-
(1993)
Proc Soc Exp Biol Med
, vol.202
, pp. 9-15
-
-
Warren, B.S.1
Naylor, M.F.2
Winberg, L.D.3
Yoshimi, N.4
Volpe, J.P.5
Gimenez-Conti, I.6
Slaga, T.J.7
-
45
-
-
0025916038
-
Overlapping loss of heterozygosity by mitotic recombination on mouse chromosome 7F1-ter in skin carcinogenesis
-
Bianchi, A.B., Navone, N.M., Aldaz, C.M., and Conti, C.J. Overlapping loss of heterozygosity by mitotic recombination on mouse chromosome 7F1-ter in skin carcinogenesis. Proc Natl Acad Sci USA 1991; 88: 7590–7594.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7590-7594
-
-
Bianchi, A.B.1
Navone, N.M.2
Aldaz, C.M.3
Conti, C.J.4
-
46
-
-
0025052266
-
Non-random duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors
-
Bianchi, A.B., Aldaz, C.M., and Conti, C.J. Non-random duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors. Proc Natl Acad Sci USA 1990; 87: 6902–6906.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6902-6906
-
-
Bianchi, A.B.1
Aldaz, C.M.2
Conti, C.J.3
-
47
-
-
0024334362
-
Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions
-
Aldaz, C.M., Trono, D., Larcher, F., Slaga, T.J., and Conti, C.J. Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions. Mol Carcinog 1989; 2: 22–26.
-
(1989)
Mol Carcinog
, vol.2
, pp. 22-26
-
-
Aldaz, C.M.1
Trono, D.2
Larcher, F.3
Slaga, T.J.4
Conti, C.J.5
-
48
-
-
0023140134
-
Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: Relevance to malignancy
-
Aldaz, C.M., Conti, C.J., Klein-Szanto, A.J.P., and Slaga, T.J. Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy. Proc Natl Acad Sci USA 1987; 84: 2029–2032.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2029-2032
-
-
Aldaz, C.M.1
Conti, C.J.2
Klein-Szanto, A.J.P.3
Slaga, T.J.4
-
49
-
-
0022841074
-
Critical genetic determinants and molecular events in multistage skin carcinogenesis
-
Slaga, T.J., O’Connell, J., Rotstein, J., Patskan, G., Morris, R., Aldaz, C.M., and Conti, C.J. Critical genetic determinants and molecular events in multistage skin carcinogenesis. Symp Fundam Cancer Res 1987; 39: 31–44.
-
(1987)
Symp Fundam Cancer Res
, vol.39
, pp. 31-44
-
-
Slaga, T.J.1
O’Connell, J.2
Rotstein, J.3
Patskan, G.4
Morris, R.5
Aldaz, C.M.6
Conti, C.J.7
-
50
-
-
85057680545
-
The health consequences of smoking: Cancer
-
DHHS/PHS 82–50179, Rockville, MD
-
U.S. Surgeon General. The Health Consequences of Smoking: Cancer, 1982. DHHS/PHS 82–50179. U.S. Public Health Service, Office on Smoking and Health; Rockville, MD.
-
(1982)
U.S. Public Health Service, Office on Smoking and Health
-
-
-
51
-
-
0031978189
-
A review of chronic inhalation studies with mainstream cigarette smoke in rats and mice
-
Coggins, C.R.E. A review of chronic inhalation studies with mainstream cigarette smoke in rats and mice. Toxicol Pathol 1998; 26: 307–314.
-
(1998)
Toxicol Pathol
, vol.26
, pp. 307-314
-
-
Coggins, C.R.E.1
-
52
-
-
0031417974
-
The carcinogenicity of environmental tobacco smoke
-
Witschi, H., Espiritu, I., Peake, J.L., Wu, K., Maronpot, R.R., and Pinkerton, K.E. The carcinogenicity of environmental tobacco smoke. Carcinogenesis 1997; 18: 575–586.
-
(1997)
Carcinogenesis
, vol.18
, pp. 575-586
-
-
Witschi, H.1
Espiritu, I.2
Peake, J.L.3
Wu, K.4
Maronpot, R.R.5
Pinkerton, K.E.6
-
53
-
-
0031418658
-
The carcinogenic potential of the gas phase of environmental tobacco smoke
-
Witschi, H., Espiritu, I., Maronpot, R.R., Pinkerton, K.E., and Jones, A.D. The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis 1997; 18: 2035–2042.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2035-2042
-
-
Witschi, H.1
Espiritu, I.2
Maronpot, R.R.3
Pinkerton, K.E.4
Jones, A.D.5
-
54
-
-
0031804604
-
Tobacco smoke as a mouse lung carcinogen
-
Witschi, H. Tobacco smoke as a mouse lung carcinogen. Exp Lung Res 1998; 24: 385–394.
-
(1998)
Exp Lung Res
, vol.24
, pp. 385-394
-
-
Witschi, H.1
-
55
-
-
0031710694
-
The effects of phenethyl isothiocyanate, N-acetylcysteine, and green tea on tobacco-smoke-induced lung tumors in strain A/J mice
-
Witschi, H., Espiritu, I., Yu, M., and Willits, N.H. The effects of phenethyl isothiocyanate, N-acetylcysteine, and green tea on tobacco-smoke-induced lung tumors in strain A/J mice. Carcinogenesis 1998; 19: 1789–1794.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1789-1794
-
-
Witschi, H.1
Espiritu, I.2
Yu, M.3
Willits, N.H.4
-
56
-
-
0032814860
-
Chemoprevention of tobacco-smoke-induced lung tumors in A/J strain mice with dietary myoinositol and dexamethasone
-
Witschi, H., Espiritu, I., and Uyeminami, D. Chemoprevention of tobacco- smoke-induced lung tumors in A/J strain mice with dietary myoinositol and dexamethasone. Carcinogenesis 1999; 20: 1375–1378.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1375-1378
-
-
Witschi, H.1
Espiritu, I.2
Uyeminami, D.3
-
57
-
-
0034020084
-
Chemoprevention of tobacco-smoke lung carcinogenesis in mice after cessation of smoke exposure
-
Witschi, H., Uyeminami, D., Moran, D., and Espiritu, I. Chemoprevention of tobacco-smoke lung carcinogenesis in mice after cessation of smoke exposure. Carcinogenesis 2000; 21: 977–982.
-
(2000)
Carcinogenesis
, vol.21
, pp. 977-982
-
-
Witschi, H.1
Uyeminami, D.2
Moran, D.3
Espiritu, I.4
-
58
-
-
0036201862
-
Lung tumors in A/J mice exposed to environmental tobacco smoke: Estimated potency and implied human risk
-
Bogen, K.T. and Witschi, H. Lung tumors in A/J mice exposed to environmental tobacco smoke: estimated potency and implied human risk. Carcinogenesis 2002; 23: 511–519.
-
(2002)
Carcinogenesis
, vol.23
, pp. 511-519
-
-
Bogen, K.T.1
Witschi, H.2
-
59
-
-
0035286298
-
Pilot studies evaluating the lung tumor yield in cigarette-smoke-exposed mice
-
D’Agostini, F., Balansky, R.M., Bennicelli, C., Lubet, R.A., Kelloff, G.J., and De Flora, S. Pilot studies evaluating the lung tumor yield in cigarette-smoke-exposed mice. Int J Oncol 2001; 18: 607–615.
-
(2001)
Int J Oncol
, vol.18
, pp. 607-615
-
-
D’Agostini, F.1
Balansky, R.M.2
Bennicelli, C.3
Lubet, R.A.4
Kelloff, G.J.5
De Flora, S.6
-
60
-
-
0037443032
-
Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke
-
De Flora, S., Balansky, R.M., D’Agostini, F., Izzotti, A., Camoirano, A., Bennicelli, C., Zhang, Z., Wang, Y., Lubet, R.A., and You, M. Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke. Cancer Res 2003; 63: 793–800.
-
(2003)
Cancer Res
, vol.63
, pp. 793-800
-
-
De Flora, S.1
Balansky, R.M.2
D’Agostini, F.3
Izzotti, A.4
Camoirano, A.5
Bennicelli, C.6
Zhang, Z.7
Wang, Y.8
Lubet, R.A.9
You, M.10
-
61
-
-
0030026224
-
Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse
-
Finch, G.L., Nikula, J.K.J., Belinsky, S.A., Barr, E.B., Stoner, G.D., and Lechner, J.F. Failure of cigarette smoke to induce or promote lung cancer in the A/J Mouse. Cancer Lett 1996; 99: 161–167.
-
(1996)
Cancer Lett
, vol.99
, pp. 161-167
-
-
Finch, G.L.1
Nikula, J.K.J.2
Belinsky, S.A.3
Barr, E.B.4
Stoner, G.D.5
Lechner, J.F.6
-
62
-
-
0031663096
-
Effect of promoter and intron 2 polymorphisms on murine lung K-ras gene expression
-
Jones-Bolin, S.E., Johansson, E., Palmisano, W.A., Anderson, M.W., Wiest, J.S., and Belinsky, S.A. Effect of promoter and intron 2 polymorphisms on murine lung K-ras gene expression. Carcinogenesis 1998; 19: 1503–1508.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1503-1508
-
-
Jones-Bolin, S.E.1
Johansson, E.2
Palmisano, W.A.3
Erson, M.W.4
Wiest, J.S.5
Belinsky, S.A.6
-
63
-
-
14444278728
-
Additional evidence that the K-ras proto-oncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene
-
Lin, L., Festing, M.F.W., Devereux, T.R., Crist, K.A., Christiansen, S.C., Wang, Y., Yang, A., Svenson, K., Paigen, B., Malkinson, A.M., and You, M. Additional evidence that the K-ras proto-oncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene. Exp Lung Res 1998; 24: 481–497.
-
(1998)
Exp Lung Res
, vol.24
, pp. 481-497
-
-
Lin, L.1
Festing, M.F.W.2
Devereux, T.R.3
Crist, K.A.4
Christiansen, S.C.5
Wang, Y.6
Yang, A.7
Svenson, K.8
Paigen, B.9
Malkinson, A.M.10
You, M.11
-
64
-
-
0025121594
-
Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes
-
Saitoh, A., Kimura, M., Takahashi, R., Yokoyama, M., Nomura, T., Izawa, M., Sekiya, T., Nishimura, S., and Katsuki, M. Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes. Oncogene 1990; 5: 1195–1200.
-
(1990)
Oncogene
, vol.5
, pp. 1195-1200
-
-
Saitoh, A.1
Kimura, M.2
Takahashi, R.3
Yokoyama, M.4
Nomura, T.5
Izawa, M.6
Sekiya, T.7
Nishimura, S.8
Katsuki, M.9
-
65
-
-
4444262212
-
Lung tumorigenicity in A/J and rasH2 transgenic mice following mainstream tobacco smoke inhalation
-
Curtin, G.M., Higuchi, M.A., Ayres, P.H., Swauger, J.E., and Mosberg, A.T. Lung tumorigenicity in A/J and rasH2 transgenic mice following mainstream tobacco smoke inhalation. Toxicol Sci 2004; 81: 26–34.
-
(2004)
Toxicol Sci
, vol.81
, pp. 26-34
-
-
Curtin, G.M.1
Higuchi, M.A.2
Ayres, P.H.3
Swauger, J.E.4
Mosberg, A.T.5
-
66
-
-
0035090708
-
Modulation of apoptosis by cigarette smoke and cancer preventive agents in the respiratory tract of rats
-
D’Agostini, F., Balansky, R.M., Izzotti, A., Lubet, R.A., Kelloff, G.J., and De Flora, S. Modulation of apoptosis by cigarette smoke and cancer preventive agents in the respiratory tract of rats. Carcinogenesis 2001; 22: 375–380.
-
(2001)
Carcinogenesis
, vol.22
, pp. 375-380
-
-
D’Agostini, F.1
Balansky, R.M.2
Izzotti, A.3
Lubet, R.A.4
Kelloff, G.J.5
De Flora, S.6
-
68
-
-
0032211455
-
Short-and intermediate-term carcinogenicity testing—a review
-
Part 2: Available experimental models
-
Enzmann, H., Iatropoulos, M., Brunnemann, K.D., Bomhard, E., Ahr, H.J., Schlueter, G., and Williams, G.M. Short-and intermediate-term carcinogenicity testing—a review. Part 2: Available experimental models. Food Chem Toxicol 1998; 36: 997–1013.
-
(1998)
Food Chem Toxicol
, vol.36
, pp. 997-1013
-
-
Enzmann, H.1
Iatropoulos, M.2
Brunnemann, K.D.3
Bomhard, E.4
Ahr, H.J.5
Schlueter, G.6
Williams, G.M.7
-
69
-
-
85018873902
-
Letter to the editor: Response to Dr. Witschi’s letter
-
Wagner, B.M. Letter to the editor: response to Dr. Witschi’s letter. Inhal Toxicol 2001; 13: 731–735.
-
(2001)
Inhal Toxicol
, vol.13
, pp. 731-735
-
-
Wagner, B.M.1
-
70
-
-
1642378592
-
A responsive, sensitive, and reproducible dermal tumor promotion assay for the comparative evaluation of cigarette smoke condensates
-
Meckley, D.R., Hayes, J.R., Van Kampen, K.R., Mosberg, A.T., and Swauger, J.E. A responsive, sensitive, and reproducible dermal tumor promotion assay for the comparative evaluation of cigarette smoke condensates. Regul Toxicol Pharmacol 2004; 39: 135–149.
-
(2004)
Regul Toxicol Pharmacol
, vol.39
, pp. 135-149
-
-
Meckley, D.R.1
Hayes, J.R.2
Van Kampen, K.R.3
Mosberg, A.T.4
Swauger, J.E.5
-
71
-
-
1642358993
-
Comparative study of smoke condensates from 1R4F cigarettes that burn tobacco versus ECLIPSE cigarettes that primarily heat tobacco in the SENCAR mouse dermal tumor promotion assay
-
Meckley, D.R., Hayes, J.R., Van Kampen, K.R., Ayres, P.H., Mosberg, A.T., and Swauger, J.E. Comparative study of smoke condensates from 1R4F cigarettes that burn tobacco versus ECLIPSE cigarettes that primarily heat tobacco in the SENCAR mouse dermal tumor promotion assay. Food Chem Toxicol 2004; 42: 851–863.
-
(2004)
Food Chem Toxicol
, vol.42
, pp. 851-863
-
-
Meckley, D.R.1
Hayes, J.R.2
Van Kampen, K.R.3
Ayres, P.H.4
Mosberg, A.T.5
Swauger, J.E.6
-
72
-
-
85057686584
-
-
Gori, GB, Deputy Director of the Division of Cancer Cause and Prevention, National Cancer Institute; Bethesda, MD
-
Toward Less Hazardous Cigarettes; National Cancer Institute Smoking and Health Program; Gori, GB, Deputy Director of the Division of Cancer Cause and Prevention, National Cancer Institute; Bethesda, MD (1976–1980).
-
(1976)
Toward Less Hazardous Cigarettes; National Cancer Institute Smoking and Health Program
-
-
-
73
-
-
0014560848
-
A study of tobacco carcinogenesis. X. Tumor-promoting activity
-
Wynder, E.L. and Hoffmann, D. A study of tobacco carcinogenesis. X. Tumor- promoting activity. Cancer 1969; 24: 289–301.
-
(1969)
Cancer
, vol.24
, pp. 289-301
-
-
Wynder, E.L.1
Hoffmann, D.2
-
74
-
-
0015043086
-
A study of tobacco carcinogenesis. XI. Tumor initiators, tumor accelerators, and tumor-promoting activity of condensate fractions
-
Hoffmann, D. and Wynder, E.L. A study of tobacco carcinogenesis. XI. Tumor initiators, tumor accelerators, and tumor-promoting activity of condensate fractions. Cancer 1971; 27: 848–864.
-
(1971)
Cancer
, vol.27
, pp. 848-864
-
-
Hoffmann, D.1
Wynder, E.L.2
-
75
-
-
0000980275
-
A study of tobacco carcinogenesis. I. The primary fractions
-
Wynder, E.L. and Wright, G. A study of tobacco carcinogenesis. I. The primary fractions. Cancer 1957; 10: 255–271.
-
(1957)
Cancer
, vol.10
, pp. 255-271
-
-
Wynder, E.L.1
Wright, G.2
-
76
-
-
0000980274
-
A study of tobacco carcinogenesis. II. Dose-response studies
-
Wynder, E.L., Kopf, P., and Ziegler, H. A study of tobacco carcinogenesis. II. Dose-response studies. Cancer 1957; 10: 1193–1200.
-
(1957)
Cancer
, vol.10
, pp. 1193-1200
-
-
Wynder, E.L.1
Kopf, P.2
Ziegler, H.3
-
77
-
-
0000512232
-
Effect of concentrations of benzopyrene in skin carcinogenesis
-
Wynder, E.L., Fritz, L., and Furth, N. Effect of concentrations of benzopyrene in skin carcinogenesis. J Natl Cancer Inst 1957; 19: 361–370.
-
(1957)
J Natl Cancer Inst
, vol.19
, pp. 361-370
-
-
Wynder, E.L.1
Fritz, L.2
Furth, N.3
-
78
-
-
0000319255
-
Study of tobacco carcinogenesis. VII. The study of the higher polycyclic hydrocarbons
-
Wynder, E.L. and Hoffmann, D. A study of tobacco carcinogenesis. VII. The study of the higher polycyclic hydrocarbons. Cancer 1959; 12: 1079–1086.
-
(1959)
Cancer
, vol.12
, pp. 1079-1086
-
-
Wynder, E.L.1
Hoffmann, D.2
-
79
-
-
0001137045
-
A study of tobacco carcinogenesis. VIII. The role of the acidic fractions as promoters
-
Wynder, E.L. and Hoffmann, D. A study of tobacco carcinogenesis. VIII. The role of the acidic fractions as promoters. Cancer 1961; 14: 1306–1315.
-
(1961)
Cancer
, vol.14
, pp. 1306-1315
-
-
Wynder, E.L.1
Hoffmann, D.2
-
80
-
-
0000344894
-
Incomplete carcinogens in cigarette smoke condensate: Tumour-promotion by a phenolic fraction
-
Roe, F.J.C., Salaman, M.H., and Cohen, J. Incomplete carcinogens in cigarette smoke condensate: tumour-promotion by a phenolic fraction. Br J Cancer 1959; 13: 623–633.
-
(1959)
Br J Cancer
, vol.13
, pp. 623-633
-
-
Roe, F.J.C.1
Salaman, M.H.2
Cohen, J.3
-
81
-
-
0000608651
-
The cocarcinogenic activity of cigarette tobacco tar
-
Gellhorn, A. The cocarcinogenic activity of cigarette tobacco tar. Cancer Res 1958; 18: 510–517.
-
(1958)
Cancer Res
, vol.18
, pp. 510-517
-
-
Gellhorn, A.1
-
82
-
-
0013962415
-
The tumor-promoting agents of tobacco leaf and tobacco smoke condensate
-
Van Duuren, B.L., Sivak, A., Segal, A., Orris, L., and Langseth, L. The tumor- promoting agents of tobacco leaf and tobacco smoke condensate. J Natl Cancer Inst 1966; 37: 519–526.
-
(1966)
J Natl Cancer Inst
, vol.37
, pp. 519-526
-
-
Van Duuren, B.L.1
Sivak, A.2
Segal, A.3
Orris, L.4
Langseth, L.5
-
83
-
-
0014790116
-
Initiating action of aromatic hydrocarbons in two-stage carcinogenesis
-
Van Duuren, B.L., Sivak, A., Goldschmidt, B.M., Katz, C., and Melchionne, S. Initiating action of aromatic hydrocarbons in two-stage carcinogenesis. J Natl Cancer Inst 1970; 44: 1167–1173.
-
(1970)
J Natl Cancer Inst
, vol.44
, pp. 1167-1173
-
-
Van Duuren, B.L.1
Sivak, A.2
Goldschmidt, B.M.3
Katz, C.4
Melchionne, S.5
-
84
-
-
0017197097
-
Cocarcinogenic and tumor promoting agents in tobacco carcinogenesis
-
Van Duuren, B.L. and Goldschmidt, B.M. Cocarcinogenic and tumor promoting agents in tobacco carcinogenesis. J Natl Cancer Inst 1976; 56: 1237–1242.
-
(1976)
J Natl Cancer Inst
, vol.56
, pp. 1237-1242
-
-
Van Duuren, B.L.1
Goldschmidt, B.M.2
-
85
-
-
0035681327
-
Synergistic mechanisms in carcinogenesis by poly cyclic aromatic hydrocarbons and by tobacco smoke: A biohistorical perspective with updates
-
Rubin, H. Synergistic mechanisms in carcinogenesis by poly cyclic aromatic hydrocarbons and by tobacco smoke: a biohistorical perspective with updates. Carcinogenesis 2001; 22: 1903–1930.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1903-1930
-
-
Rubin, H.1
-
86
-
-
0037152680
-
Selective clonal expansion and microenvironmental permissiveness in tobacco carcinogenesis
-
Rubin, H. Selective clonal expansion and microenvironmental permissiveness in tobacco carcinogenesis. Oncogene 2002; 21: 7392–7411.
-
(2002)
Oncogene
, vol.21
, pp. 7392-7411
-
-
Rubin, H.1
-
88
-
-
0019722277
-
Mutagenic and carcinogenic potency of extracts of diesel and related environmental emissions: Two-stage carcinogenesis in skin tumor sensitive mice (sencar)
-
Slaga, T., Triplett, L., and Nesnow, S. Mutagenic and carcinogenic potency of extracts of diesel and related environmental emissions: two-stage carcinogenesis in skin tumor sensitive mice (SENCAR). Environ Int 1981; 5: 417–423.
-
(1981)
Environ Int
, vol.5
, pp. 417-423
-
-
Slaga, T.1
Triplett, L.2
Nesnow, S.3
-
89
-
-
0021903955
-
Studies on the tumor initiating, tumor promoting, and tumor co-initiating properties of respiratory carcinogens
-
Nesnow, S., Triplett, L.L., and Slaga, TJ. Studies on the tumor initiating, tumor promoting, and tumor co-initiating properties of respiratory carcinogens. Car-cinog Compr Surv 1985; 8: 257–277.
-
(1985)
Car-Cinog Compr Surv
, vol.8
, pp. 257-277
-
-
Nesnow, S.1
Triplett, L.L.2
Slaga, T.J.3
-
90
-
-
0024486629
-
Mouse skin tumors as predictors of human lung cancer for complex emissions: An overview, skin carcinogenesis: Mechanisms of human relevance
-
Nesnow, S. Mouse skin tumors as predictors of human lung cancer for complex emissions: an overview, skin carcinogenesis: Mechanisms of human relevance. Prog Clin Biol Res 1989; 298: 347–361.
-
(1989)
Prog Clin Biol Res
, vol.298
, pp. 347-361
-
-
Nesnow, S.1
-
91
-
-
0030112306
-
The mouse skin carcinogenesis model
-
Slaga, TJ., Budunova, I.V., Gimenez-Conti, I.B., and Aldaz, C.M. The mouse skin carcinogenesis model. J Invest Dermatol Symp Proc 1996; 1: 151–156.
-
(1996)
J Invest Dermatol Symp Proc
, vol.1
, pp. 151-156
-
-
Slaga, T.J.1
Budunova, I.V.2
Gimenez-Conti, I.B.3
Aldaz, C.M.4
-
92
-
-
4444304726
-
Shortterm in vitro and in vivo analyses for assessing the tumor-promoting potentials of cigarette smoke condensates
-
Curtin, G.M., Hanausek, M., Walaszek, Z., Mosberg, A.T., and Slaga, TJ. Shortterm in vitro and in vivo analyses for assessing the tumor-promoting potentials of cigarette smoke condensates. Toxicol Sci 2004; 81: 14–25.
-
(2004)
Toxicol Sci
, vol.81
, pp. 14-25
-
-
Curtin, G.M.1
Hanausek, M.2
Walaszek, Z.3
Mosberg, A.T.4
Slaga, T.J.5
-
93
-
-
0028963615
-
Role of ornithine decarboxylase in epidermal tumorigenesis
-
Clifford, A., Morgan, D., Yuspa, S.H., Soler, A.P., and Gilmour, S. Role of ornithine decarboxylase in epidermal tumorigenesis. Cancer Res 1995; 55: 1680–1686.
-
(1995)
Cancer Res
, vol.55
, pp. 1680-1686
-
-
Clifford, A.1
Morgan, D.2
Yuspa, S.H.3
Soler, A.P.4
Gilmour, S.5
-
94
-
-
0035881620
-
Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis
-
Feith, D.J., Shantz, L.M., and Pegg, A.E. Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis. Cancer Res 2001; 61: 6073–6081.
-
(2001)
Cancer Res
, vol.61
, pp. 6073-6081
-
-
Feith, D.J.1
Shantz, L.M.2
Pegg, A.E.3
-
95
-
-
0026555236
-
Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetrade-canoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate
-
Gilmour, S.K., Robertson, F.M., Megosh, L., O’Connell, S.M., Mitchell, J., and O’Brien, T.G. Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetrade-canoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate. Carcinogenesis 1992; 13: 51–56.
-
(1992)
Carcinogenesis
, vol.13
, pp. 51-56
-
-
Gilmour, S.K.1
Robertson, F.M.2
Megosh, L.3
O’Connell, S.M.4
Mitchell, J.5
O’Brien, T.G.6
-
96
-
-
0030741841
-
Ornithine decarboxylase over-expression is a sufficient condition for tumor promotion in mouse skin
-
O’Brien, T.G., Megosh, L.C., Gilliard, G., and Soler, A.P. Ornithine decarboxylase over-expression is a sufficient condition for tumor promotion in mouse skin. Cancer Res 1997; 57: 2630–2637.
-
(1997)
Cancer Res
, vol.57
, pp. 2630-2637
-
-
O’Brien, T.G.1
Megosh, L.C.2
Gilliard, G.3
Soler, A.P.4
-
97
-
-
0031691298
-
Cooperation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin
-
Smith, M.K., Trempus, C.S., and Gilmour, S.K. Cooperation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin. Carcinogenesis 1998; 19: 1409–1415.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1409-1415
-
-
Smith, M.K.1
Trempus, C.S.2
Gilmour, S.K.3
-
98
-
-
0032522797
-
Polyamines regulate expression of the neoplastic phenotype in mouse skin
-
Soler, A.P., Gilliard, G., Megosh, L., George, K., and O’Brien, T.G. Polyamines regulate expression of the neoplastic phenotype in mouse skin. Cancer Res 1998; 58: 1654–1659.
-
(1998)
Cancer Res
, vol.58
, pp. 1654-1659
-
-
Soler, A.P.1
Gilliard, G.2
Megosh, L.3
George, K.4
O’Brien, T.G.5
-
99
-
-
0018954858
-
Tumor promotion by abrasion induced epidermal hyperplasia in the skin of mice
-
Argyris, T.S. Tumor promotion by abrasion induced epidermal hyperplasia in the skin of mice. J Invest Dermatol 1980; 75: 360–362.
-
(1980)
J Invest Dermatol
, vol.75
, pp. 360-362
-
-
Argyris, T.S.1
-
100
-
-
0019787422
-
Promotion of carcinomas by repeated abrasion in initiated skin of mice
-
Argyris, T.S. and Slaga, TJ. Promotion of carcinomas by repeated abrasion in initiated skin of mice. Cancer Res 1981; 41: 5193–5195.
-
(1981)
Cancer Res
, vol.41
, pp. 5193-5195
-
-
Argyris, T.S.1
Slaga, T.J.2
-
101
-
-
0030816210
-
Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling
-
Morris, R.J., Coulter, K, Tryson, K., and Steinberg, S.R. Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling. Cancer Res 1997; 57: 3436–3443.
-
(1997)
Cancer Res
, vol.57
, pp. 3436-3443
-
-
Morris, R.J.1
Coulter, K.2
Tryson, K.3
Steinberg, S.R.4
-
102
-
-
0000349342
-
Beryllium, cadmium, mercury and exposures in the glass manufacturing industry
-
International Agency for Research on Cancer. Beryllium, cadmium, mercury and exposures in the glass manufacturing industry. IARC Sci Pub 1993; 58: 119–238.
-
(1993)
IARC Sci Pub
, vol.58
, pp. 119-238
-
-
-
103
-
-
0034732606
-
Cadmium carcinogenesis in review
-
Waalkes, M.P. Cadmium carcinogenesis in review. J Inorg Biochem 2000; 79: 241–244.
-
(2000)
J Inorg Biochem
, vol.79
, pp. 241-244
-
-
Waalkes, M.P.1
-
104
-
-
0020698321
-
Carcinogenicity of cadmium chloride aerosols in wistar rats
-
Takenaka, S., Oldiges, H., Konig, H., Hochrainer, D., and Oberdorster, G. Carcinogenicity of cadmium chloride aerosols in Wistar rats. J Natl Cancer Inst 1983; 70: 367–373.
-
(1983)
J Natl Cancer Inst
, vol.70
, pp. 367-373
-
-
Takenaka, S.1
Oldiges, H.2
Konig, H.3
Hochrainer, D.4
Oberdorster, G.5
-
105
-
-
0345708255
-
Cadmium carcinogenesis
-
Waalkes, M.P. Cadmium carcinogenesis. Mutat Res 2003; 533: 107–120.
-
(2003)
Mutat Res
, vol.533
, pp. 107-120
-
-
Waalkes, M.P.1
-
106
-
-
0030798331
-
Cadmium-induced oxidative cellular damage in human fetal lung fibroblasts (MRC-5 cells)
-
Yang, C.-F., Shen, H.-M., Shen, Y., Zhuang, Z.-X., and Ong, C.-N. Cadmium- induced oxidative cellular damage in human fetal lung fibroblasts (MRC-5 cells). Environ Health Perspect 1997; 105: 712–716.
-
(1997)
Environ Health Perspect
, vol.105
, pp. 712-716
-
-
Yang, C.-F.1
Shen, H.-M.2
Shen, Y.3
Zhuang, Z.-X.4
Ong, C.-N.5
-
107
-
-
0029915960
-
Effect of arsenic and cadmium on the persistence of mutagen-induced dna lesions in human cells
-
Hartmann, A. and Speit, G. Effect of arsenic and cadmium on the persistence of mutagen-induced DNA lesions in human cells. Environ Mol Mutat 1996; 27: 98–104.
-
(1996)
Environ Mol Mutat
, vol.27
, pp. 98-104
-
-
Hartmann, A.1
Speit, G.2
-
108
-
-
0031843623
-
Disturbance of DNA damage recognition after UV-irradiation by nickel (II) and cadmium (II) in mammalian cells
-
Hartmann, M. and Hartwig, A. Disturbance of DNA damage recognition after UV-irradiation by nickel (II) and cadmium (II) in mammalian cells. Carcinogenesis 1998; 19: 617–621.
-
(1998)
Carcinogenesis
, vol.19
, pp. 617-621
-
-
Hartmann, M.1
Hartwig, A.2
-
109
-
-
0031424866
-
Induction and repair inhibition of oxidative DNA damage by nickel (II) and cadmium (II) in mammalian cells
-
Dally, H. and Hartwig, A. Induction and repair inhibition of oxidative DNA damage by nickel (II) and cadmium (II) in mammalian cells. Carcinogenesis 1997; 18: 1021–1026.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1021-1026
-
-
Dally, H.1
Hartwig, A.2
-
110
-
-
0037184672
-
Proto-oncogene amplification and overexpression in cadmium-induced cell transformation
-
Spruill, M.D., Song, B., Whong, W.-Z., and Ong, T. Proto-oncogene amplification and overexpression in cadmium-induced cell transformation. J Toxicol Environ Health 2002; 65: 2131–2144.
-
(2002)
J Toxicol Environ Health
, vol.65
, pp. 2131-2144
-
-
Spruill, M.D.1
Song, B.2
Whong, W.-Z.3
Ong, T.4
-
111
-
-
0034989784
-
Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun, and c-myc protooncogenes: Role of cellular calcium and reactive oxygen species
-
Joseph, P., Muchnok, T.K., Klishis, M.L., Roberts, J.R., Antonini, J.M., Whong, W.Z., and Ong, T. Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun, and c-myc protooncogenes: role of cellular calcium and reactive oxygen species. Toxicol Sci 2001; 61: 295–303.
-
(2001)
Toxicol Sci
, vol.61
, pp. 295-303
-
-
Joseph, P.1
Muchnok, T.K.2
Klishis, M.L.3
Roberts, J.R.4
Antonini, J.M.5
Whong, W.Z.6
Ong, T.7
-
112
-
-
0034193451
-
Cadmium induces c-myc, p53, and c-jun expression in normal human prostate epithelial cells as a prelude to apoptosis
-
Achanzar, W.E., Achanzar, K.B., Lewis, J.G., Webber, M.M., and Waalkes, M.P. Cadmium induces c-myc, p53, and c-jun expression in normal human prostate epithelial cells as a prelude to apoptosis. Toxicol Appl Pharmacol 2000; 164: 291–300.
-
(2000)
Toxicol Appl Pharmacol
, vol.164
, pp. 291-300
-
-
Achanzar, W.E.1
Achanzar, K.B.2
Lewis, J.G.3
Webber, M.M.4
Waalkes, M.P.5
-
113
-
-
0029812847
-
Induction of c-myc and c-jun proto-oncogene expression in rat L6 myoblasts by cadmium is inhibited by zinc preinduction of the metallothionein gene
-
Abshire, M.K., Busard, G.S., Shiraishi, N., and Waalkes, M.P. Induction of c-myc and c-jun proto-oncogene expression in rat L6 myoblasts by cadmium is inhibited by zinc preinduction of the metallothionein gene. J Toxicol Environ Health 1996; 48: 359–377.
-
(1996)
J Toxicol Environ Health
, vol.48
, pp. 359-377
-
-
Abshire, M.K.1
Busard, G.S.2
Shiraishi, N.3
Waalkes, M.P.4
-
114
-
-
0029802357
-
Effects of cadmium on cellular proto-oncogene expression
-
Hechtenberg, S., Schafer, T., Benters, J., and Beyersmann, D. Effects of cadmium on cellular proto-oncogene expression. Ann Clin Lab Sci 1996; 26: 512–521.
-
(1996)
Ann Clin Lab Sci
, vol.26
, pp. 512-521
-
-
Hechtenberg, S.1
Schafer, T.2
Benters, J.3
Beyersmann, D.4
-
115
-
-
0030026739
-
Metal-lothionein-l and ll knockout mice are sensitive to cadmium-induced liver mRNA expression of c-jun and p53
-
Zheng, H., Liu, J., Choo, K.H., Michalska, A.E., and Klaassen, C.D. Metal- lothionein-l and ll knockout mice are sensitive to cadmium-induced liver mRNA expression of c-jun and p53. Toxicol Appl Pharmacol 1996; 136: 229–235.
-
(1996)
Toxicol Appl Pharmacol
, vol.136
, pp. 229-235
-
-
Zheng, H.1
Liu, J.2
Choo, K.H.3
Michalska, A.E.4
Klaassen, C.D.5
-
116
-
-
0034812905
-
Lnvolvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo
-
Huang, C., Zhang, Q., Li, J., Shi, X., Castranova, V., Ju, G., Costa, M., and Dong, Z. lnvolvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo. Mol Cell Biochem 2001; 222: 141–147.
-
(2001)
Mol Cell Biochem
, vol.222
, pp. 141-147
-
-
Huang, C.1
Zhang, Q.2
Li, J.3
Shi, X.4
Castranova, V.5
Ju, G.6
Costa, M.7
Dong, Z.8
-
117
-
-
0037960155
-
Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation
-
Takiguchi, M., Achanzar, W.E., Qu, W., Li, G., and Waalkes, M.P. Effects of cadmium on DNA-(cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. Exp Cell Res 2003; 286: 355–365.
-
(2003)
Exp Cell Res
, vol.286
, pp. 355-365
-
-
Takiguchi, M.1
Achanzar, W.E.2
Qu, W.3
Li, G.4
Waalkes, M.P.5
-
118
-
-
0039136305
-
Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells
-
Meplan, C., Mann, K., and Hainaut, P. Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. J Biol Chem 1999; 274: 31663–31670.
-
(1999)
J Biol Chem
, vol.274
, pp. 31663-31670
-
-
Meplan, C.1
Mann, K.2
Hainaut, P.3
-
119
-
-
0034194773
-
Studies on the mechanisms of cadmium-induced blockage of apoptosis: Possible role of caspase-3 inhibition
-
Yuan, C., Kadiiska, M.B., Achanzar, W.E., Mason, R., and Waalkes, M.P. Studies on the mechanisms of cadmium-induced blockage of apoptosis: possible role of caspase-3 inhibition. Toxicol Appl Pharmacol 2000; 164: 321–329.
-
(2000)
Toxicol Appl Pharmacol
, vol.164
, pp. 321-329
-
-
Yuan, C.1
Kadiiska, M.B.2
Achanzar, W.E.3
Mason, R.4
Waalkes, M.P.5
-
120
-
-
0031706254
-
Cadmium suppresses apoptosis induced by chromium
-
Shimada, H., Shiao, Y.H., Shibata, M.A., and Waalkes, M.P. Cadmium suppresses apoptosis induced by chromium. J Toxicol Environ Health 1998; 54: 159–168.
-
(1998)
J Toxicol Environ Health
, vol.54
, pp. 159-168
-
-
Shimada, H.1
Shiao, Y.H.2
Shibata, M.A.3
Waalkes, M.P.4
-
121
-
-
0036680443
-
Altered apoptotic gene expression and acquired apoptotic resistance in cadmium-transformed human prostate epithelial cells
-
Achanzar, W.E., Webber, M.M., and Waalkes, M.P. Altered apoptotic gene expression and acquired apoptotic resistance in cadmium-transformed human prostate epithelial cells. Prostate 2002; 52: 236–244.
-
(2002)
Prostate
, vol.52
, pp. 236-244
-
-
Achanzar, W.E.1
Webber, M.M.2
Waalkes, M.P.3
-
122
-
-
0030051802
-
Modulation of the antioxidant defense as a factor in apoptosis
-
Briehl, M.M. and Baker, A.F. Modulation of the antioxidant defense as a factor in apoptosis. Cell Death Different 1996; 3: 63–70.
-
(1996)
Cell Death Different
, vol.3
, pp. 63-70
-
-
Briehl, M.M.1
Baker, A.F.2
-
123
-
-
0031954785
-
Metallothionein and apoptosis in primary human hepatocellular carcinoma and metastatic adenocarcinoma
-
Deng, D.X., Chakrabarti, S., Waalkes, M.P., and Cherian, M.G. Metallothionein and apoptosis in primary human hepatocellular carcinoma and metastatic adenocarcinoma. Histopathology 1998; 32: 340–347.
-
(1998)
Histopathology
, vol.32
, pp. 340-347
-
-
Deng, D.X.1
Chakrabarti, S.2
Waalkes, M.P.3
Cherian, M.G.4
-
124
-
-
0032557458
-
Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-k-b and activated protein-1
-
Manna, S.K., Zhang, H.J., Yan, T., Oberley, L.W., and Aggarwal, B.B. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor- induced apoptosis and activation of nuclear transcription factor-K-B and activated protein-1. J Biol Chem 1998; 273: 13245–13254.
-
(1998)
J Biol Chem
, vol.273
, pp. 13245-13254
-
-
Manna, S.K.1
Zhang, H.J.2
Yan, T.3
Oberley, L.W.4
Aggarwal, B.B.5
-
125
-
-
0030799592
-
Enhanced apoptosis in metallothionein null cells
-
Kondo, Y., Rusnak, J.M., Hoyt, D.G., Settineri, C.E., Pitt, B.R., and Lazo, J.S. Enhanced apoptosis in metallothionein null cells. Mol Pharmacol 1997; 52: 195–201.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 195-201
-
-
Kondo, Y.1
Rusnak, J.M.2
Hoyt, D.G.3
Settineri, C.E.4
Pitt, B.R.5
Lazo, J.S.6
-
126
-
-
0029925648
-
The protective role of glutathione peroxidase in apoptosis induced by reactive oxygen species
-
Kayanoki, Y., Fujii, J., lslam, K.N., Suzuki, K., Kawata, S., Matsuzawa, Y., and Taniguchi, N. The protective role of glutathione peroxidase in apoptosis induced by reactive oxygen species. J Biochem 1996; 19: 817–822.
-
(1996)
J Biochem
, vol.19
, pp. 817-822
-
-
Kayanoki, Y.1
Fujii, J.2
Lslam, K.N.3
Suzuki, K.4
Kawata, S.5
Matsuzawa, Y.6
Taniguchi, N.7
-
127
-
-
0030040429
-
Lntracellular redox changes during apoptosis
-
Slater, A.F., Stefan, C., Nobel, l., van den Dobbelsteen, D.J., and Orrenius, S. lntracellular redox changes during apoptosis. Cell Death Different 1996; 3: 57–62.
-
(1996)
Cell Death Different
, vol.3
, pp. 57-62
-
-
Slater, A.F.1
Stefan, C.2
Nobel, L.3
Van Den Dobbelsteen, D.J.4
Orrenius, S.5
-
128
-
-
0025231453
-
Cross-tolerance to hyperoxia following cadmium aerosol pretreatment
-
Hart, B.A., Voss, G.W., Shatos, M., and Doherty, J. Cross-tolerance to hyperoxia following cadmium aerosol pretreatment. Toxicol Appl Pharmacol 1990; 103: 255–270.
-
(1990)
Toxicol Appl Pharmacol
, vol.103
, pp. 255-270
-
-
Hart, B.A.1
Voss, G.W.2
Shatos, M.3
Doherty, J.4
-
129
-
-
0024819942
-
Pulmonary tolerance to cadmium following cadmium aerosol pretreatment
-
Hart, B.A., Voss, G.W., and Willean, C.L. Pulmonary tolerance to cadmium following cadmium aerosol pretreatment. Toxicol Appl Pharmacol 1989; 101: 447–460.
-
(1989)
Toxicol Appl Pharmacol
, vol.101
, pp. 447-460
-
-
Hart, B.A.1
Voss, G.W.2
Willean, C.L.3
-
130
-
-
0022619077
-
Cellular and biochemical response of the rat lung to repeated inhalation of cadmium aerosols
-
Hart, B.A. Cellular and biochemical response of the rat lung to repeated inhalation of cadmium aerosols. Toxicol Appl Pharmacol 1986; 82: 281–291.
-
(1986)
Toxicol Appl Pharmacol
, vol.82
, pp. 281-291
-
-
Hart, B.A.1
-
131
-
-
0029562886
-
Increased oxidant resistance of alveolar epithelial type II cells isolated from rats following repeated exposure to cadmium aerosols
-
Hart, B.A., Eneman, J.D., Gong, Q., and Durieux-Lu, C.C. Increased oxidant resistance of alveolar epithelial type II cells isolated from rats following repeated exposure to cadmium aerosols. Toxicol Lett 1995; 81: 131–139.
-
(1995)
Toxicol Lett
, vol.81
, pp. 131-139
-
-
Hart, B.A.1
Eneman, J.D.2
Gong, Q.3
Durieux-Lu, C.C.4
-
132
-
-
0029019753
-
In vivo expression of metallothionein in rat alveolar macrophages and type ii epithelial cells following repeated cadmium aerosol exposures
-
Hart, B.A., Gong, Q., Eneman, J.D., and Durieux-Lu, C.C. In vivo expression of metallothionein in rat alveolar macrophages and type II epithelial cells following repeated cadmium aerosol exposures. Toxicol Appl Pharmacol 1995; 133: 82–90.
-
(1995)
Toxicol Appl Pharmacol
, vol.133
, pp. 82-90
-
-
Hart, B.A.1
Gong, Q.2
Eneman, J.D.3
Durieux-Lu, C.C.4
-
133
-
-
0028567070
-
The role of cellular antioxidant defense in oxidant carcinogenesis
-
Cerutti, P., Ghosh, R., Oya, Y., and Amstad, P. The role of cellular antioxidant defense in oxidant carcinogenesis. Environ Health Perspect 1994; 102: 123–129.
-
(1994)
Environ Health Perspect
, vol.102
, pp. 123-129
-
-
Cerutti, P.1
Ghosh, R.2
Oya, Y.3
Amstad, P.4
-
134
-
-
0028068186
-
Free radicals, antioxidants, and human disease: Curiosity, cause, or consequence
-
Halliwell, B. Free radicals, antioxidants, and human disease: curiosity, cause, or consequence. The Lancet 1994; 344: 721–724.
-
(1994)
The Lancet
, vol.344
, pp. 721-724
-
-
Halliwell, B.1
-
135
-
-
0034608778
-
Suppressed oxidant-induced apoptosis in cadmium adapted alveolar epithelial cells and its potential involvement in cadmium carcinogenesis
-
Eneman, J.D., Potts, R.J., Osier, M., Shukla, G.S., Lee, C.H., Chiu, J.-F., and Hart, B.A. Suppressed oxidant-induced apoptosis in cadmium adapted alveolar epithelial cells and its potential involvement in cadmium carcinogenesis. Toxicol 2000; 147: 215–228.
-
(2000)
Toxicol
, vol.147
, pp. 215-228
-
-
Eneman, J.D.1
Potts, R.J.2
Osier, M.3
Shukla, G.S.4
Lee, C.H.5
Chiu, J.-F.6
Hart, B.A.7
-
136
-
-
0032539871
-
Bcl-2 expression causes redistribution of glutathione to the nucleus
-
Voehringer, D.W., McConkey, D.J., McDonnel, T.J., Brisbay, S., and Meyn, R.E. Bcl-2 expression causes redistribution of glutathione to the nucleus. Proc Natl Acad Sci USA 1998; 95: 2956–2960.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2956-2960
-
-
Voehringer, D.W.1
McConkey, D.J.2
McDonnel, T.J.3
Brisbay, S.4
Meyn, R.E.5
-
137
-
-
0035819927
-
Cadmium adaptation in the lung—a double-edged sword?
-
Hart, B.A., Potts, R.J., and Watkin, R.D. Cadmium adaptation in the lung—a double-edged sword? Toxicology 2001; 160: 65–70.
-
(2001)
Toxicology
, vol.160
, pp. 65-70
-
-
Hart, B.A.1
Potts, R.J.2
Watkin, R.D.3
-
138
-
-
77957179141
-
Six-month exposure of strain A/J mice to cigarette sidestream smoke: Cell kinetics and lung tumor data
-
Witschi, H., Oreffo, V.I.C., and Pinkerton, K.E. Six-month exposure of strain A/J mice to cigarette sidestream smoke: cell kinetics and lung tumor data. Fundam Appl Toxicol 1995; 26: 32–40.
-
(1995)
Fundam Appl Toxicol
, vol.26
, pp. 32-40
-
-
Witschi, H.1
Oreffo, V.I.C.2
Pinkerton, K.E.3
-
139
-
-
0036667359
-
A mouse lung tumor model of tobacco smoke carcinogenesis
-
Witschi, H., Espiritu, I., Dance, S.T., and Miller, M.S. A mouse lung tumor model of tobacco smoke carcinogenesis. Toxicol Sci 2002; 68: 322–330.
-
(2002)
Toxicol Sci
, vol.68
, pp. 322-330
-
-
Witschi, H.1
Espiritu, I.2
Dance, S.T.3
Miller, M.S.4
-
140
-
-
0037295021
-
Modulation of cigarette-smoke-related end points in mutagenesis and carcinogenesis
-
De Flora, S., D’Agostini, F., Balansky, R., Camoirano, A., Bennicelli, C., Bagnasco, M., Cartiglia, C., Tampa, E., Longobardi, M. G., Lubet, R. A., and Izzotti, A. Modulation of cigarette-smoke-related end points in mutagenesis and carcinogenesis. Mutat Res 2003; 523–524: 237–252.
-
(2003)
Mutat Res
, vol.523-524
, pp. 237-252
-
-
De Flora, S.1
D’Agostini, F.2
Balansky, R.3
Camoirano, A.4
Bennicelli, C.5
Bagnasco, M.6
Cartiglia, C.7
Tampa, E.8
Longobardi, M.G.9
Lubet, R.A.10
Izzotti, A.11
-
141
-
-
0031777185
-
Cyclo-oxygenases 1 and 2
-
Vane, J.R., Bakhle, Y.S., and Botting, R.M. Cyclo-oxygenases 1 and 2. Annu Rev Pharmacol Toxicol 1998; 38: 97–120.
-
(1998)
Annu Rev Pharmacol Toxicol
, vol.38
, pp. 97-120
-
-
Vane, J.R.1
Bakhle, Y.S.2
Botting, R.M.3
-
142
-
-
0035468642
-
Cyclo-oxygenase 2: A pharmacological target for the prevention of cancer
-
Dannenberg, A.J., Altorki, N.K., Boyle, J.O., Dang, C., Howe, L.R., Weksler, B.B., and Subbaramaiah, K. Cyclo-oxygenase 2: A pharmacological target for the prevention of cancer. Lancet Oncol 2001; 2: 544–551.
-
(2001)
Lancet Oncol
, vol.2
, pp. 544-551
-
-
Dannenberg, A.J.1
Altorki, N.K.2
Boyle, J.O.3
Dang, C.4
Howe, L.R.5
Weksler, B.B.6
Subbaramaiah, K.7
-
143
-
-
0033939938
-
Cyclo-oxygenase-2 expression is abundant in alveolar type II cells in lung-cancer-sensitive mouse strains and in premalignant lesions
-
Wardlaw, S.A., March, T.H., and Belinsky, S.A. Cyclo-oxygenase-2 expression is abundant in alveolar type II cells in lung-cancer-sensitive mouse strains and in premalignant lesions. Carcinogenesis 2000; 21: 1371–1377.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1371-1377
-
-
Wardlaw, S.A.1
March, T.H.2
Belinsky, S.A.3
-
144
-
-
0034008165
-
High cyclo-oxygenase 1 (Cox-1) and cyclo-oxygenase-2 (cox-2) contents in mouse lung tumors
-
Bauer, A.K., Dwyer-Nield, L.D., and Malkinson, A.M. High cyclo-oxygenase 1 (COX-1) and cyclo-oxygenase-2 (COX-2) contents in mouse lung tumors. Carcinogenesis 2000; 21: 543–550.
-
(2000)
Carcinogenesis
, vol.21
, pp. 543-550
-
-
Bauer, A.K.1
Dwyer-Nield, L.D.2
Malkinson, A.M.3
-
145
-
-
0037126069
-
Transgenic cyclo-oxygenase-2 overexpression sensitizes mouse skin for carcinogenesis
-
Muller-Decker, K., Neufang, G., Berger, I., Neumann, M., Marks, F., and Furstenberger, G. Transgenic cyclo-oxygenase-2 overexpression sensitizes mouse skin for carcinogenesis. Proc Natl Acad Sci USA 2002; 99: 12483–12488.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12483-12488
-
-
Muller-Decker, K.1
Neufang, G.2
Berger, I.3
Neumann, M.4
Marks, F.5
Furstenberger, G.6
-
146
-
-
0036672423
-
The mouse rasH2/BHT model as an in vivo rapid assay for lung carcinogens
-
Umemura, T., Kodama, Y., Hioki, K., Nomura, T., Nishikawa, A., Hirose, M., and Kurokawa, Y. The mouse rasH2/BHT model as an in vivo rapid assay for lung carcinogens. Jpn J Cancer Res 2002; 93: 861–866.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 861-866
-
-
Umemura, T.1
Kodama, Y.2
Hioki, K.3
Nomura, T.4
Nishikawa, A.5
Hirose, M.6
Kurokawa, Y.7
-
147
-
-
0036597883
-
Tumor-promoting effect of phenolphthalein on development of lung tumors induced by n-ethyl-n-nitrosourea in transgenic mice carrying human prototype c-Ha-rasgene
-
Imaoka, M., Kashida, Y., Watanabe, T., Ueda, M., Onodera, H., Hirose, M., and Mitsumori, K. Tumor-promoting effect of phenolphthalein on development of lung tumors induced by N-ethyl-N-nitrosourea in transgenic mice carrying human prototype c-Ha-ras gene. J Vet Med Sci 2002; 64: 489–493.
-
(2002)
J Vet Med Sci
, vol.64
, pp. 489-493
-
-
Imaoka, M.1
Kashida, Y.2
Watanabe, T.3
Ueda, M.4
Onodera, H.5
Hirose, M.6
Mitsumori, K.7
-
148
-
-
0030965154
-
Induction of cytosolic phospholipase a2 by oncogenic ras in human non-small-cell lung cancer
-
Heasley, L.E., Thaler, S., Nicks, M., Price, B., Skorecki, K., and Nemenoff, R.A. Induction of cytosolic phospholipase A2 by oncogenic ras in human non-small-cell lung cancer. J Biol Chem 1997; 272: 14501–14504.
-
(1997)
J Biol Chem
, vol.272
, pp. 14501-14504
-
-
Heasley, L.E.1
Thaler, S.2
Nicks, M.3
Price, B.4
Skorecki, K.5
Nemenoff, R.A.6
-
149
-
-
0032555484
-
Induction of cyclooxygenase-2 by activated ha-ras oncogene in rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway
-
Sheng, H., Willians, C.S., Shao, J., Liang, P., DuBois, R.N., and Beauchamp, R.D. Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J Biol Chem 1998; 273: 22120–22127.
-
(1998)
J Biol Chem
, vol.273
, pp. 22120-22127
-
-
Sheng, H.1
Willians, C.S.2
Shao, J.3
Liang, P.4
DuBois, R.N.5
Beauchamp, R.D.6
-
150
-
-
0036845260
-
P53-mediated induction of cox-2 counteracts p53-or genotoxic stress-induced apoptosis
-
Han, J.A., Kim, J.I., Ongusaha, P.P., Hwang, D.H., Ballou, L.R., Mahale, A., Aaronson, S.A., and Lee, S.W. P53-mediated induction of COX-2 counteracts p53- or genotoxic stress-induced apoptosis. EMBO J 2002; 21: 5635–5644.
-
(2002)
EMBO J
, vol.21
, pp. 5635-5644
-
-
Han, J.A.1
Kim, J.I.2
Ongusaha, P.P.3
Hwang, D.H.4
Ballou, L.R.5
Mahale, A.6
Aaronson, S.A.7
Lee, S.W.8
-
151
-
-
0842281343
-
A mechanistic study of cigarette smoke and cyclooxygenase-2 on proliferation of gastric cancer cells
-
Shin, V.Y., Liu, E.S., Ye, Y.N., Koo, M.W., Chu, K.M., and Cho, C.H. A mechanistic study of cigarette smoke and cyclooxygenase-2 on proliferation of gastric cancer cells. Toxicol Appl Pharmacol 2004; 195: 103–112.
-
(2004)
Toxicol Appl Pharmacol
, vol.195
, pp. 103-112
-
-
Shin, V.Y.1
Liu, E.S.2
Ye, Y.N.3
Koo, M.W.4
Chu, K.M.5
Cho, C.H.6
-
152
-
-
0025603293
-
The carcinogenic potential of inhaled diesel exhaust: A particle effect?
-
Oberdorster, G. and Yu, C.P. The carcinogenic potential of inhaled diesel exhaust: a particle effect? J Aerosol Sci 1990; 21: S397–401.
-
(1990)
J Aerosol Sci
, vol.21
, pp. S397-S401
-
-
Oberdorster, G.1
Yu, C.P.2
-
153
-
-
0028534540
-
Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers
-
Janssen, Y.M.W., Heintz, N.H., Marsh, J.P., Borm, P.J.A., and Mossman, B.T. Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers. Am J Respir Cell Mol Biol 1994; 11: 522–530.
-
(1994)
Am J Respir Cell Mol Biol
, vol.11
, pp. 522-530
-
-
Janssen, Y.M.W.1
Heintz, N.H.2
Marsh, J.P.3
Borm, P.J.A.4
Mossman, B.T.5
-
154
-
-
0027661830
-
Cell and tissue responses to oxidative damage
-
Janssen, Y.M.W., Borm, P.J.A., Van Houten, B., and Mossman, B.T. Cell and tissue responses to oxidative damage. Lab Invest 1993; 69: 261–274.
-
(1993)
Lab Invest
, vol.69
, pp. 261-274
-
-
Janssen, Y.M.W.1
Borm, P.J.A.2
Van Houten, B.3
Mossman, B.T.4
-
155
-
-
0025902273
-
Endogenous mutagens and the causes of aging and cancer
-
Ames, B.N. and Gold, L.S. Endogenous mutagens and the causes of aging and cancer. Mutat Res 1991; 250: 3–16.
-
(1991)
Mutat Res
, vol.250
, pp. 3-16
-
-
Ames, B.N.1
Gold, L.S.2
-
156
-
-
0029069484
-
A strategy for establishing mode of action of chemical carcinogens as a guide for approaches to risk assessments
-
Butterworth, B.E., Conolly, R.B., and Morgan, K.T. A strategy for establishing mode of action of chemical carcinogens as a guide for approaches to risk assessments. Cancer Lett 1995; 93: 129–146.
-
(1995)
Cancer Lett
, vol.93
, pp. 129-146
-
-
Butterworth, B.E.1
Conolly, R.B.2
Morgan, K.T.3
-
157
-
-
0030297341
-
Particles, inflammation and respiratory tract carcinogenesis
-
Borm, PJ.A., and Driscoll, K.E. Particles, inflammation and respiratory tract carcinogenesis. Toxicol Lett 1996; 88: 109–113.
-
(1996)
Toxicol Lett
, vol.88
, pp. 109-113
-
-
Borm, P.J.A.1
Driscoll, K.E.2
-
158
-
-
0027669902
-
Cytokines and pulmonary fibrosis
-
Gauldie, J., Jordana, M., and Cox, G. Cytokines and pulmonary fibrosis. Thorax 1993; 48: 931–935.
-
(1993)
Thorax
, vol.48
, pp. 931-935
-
-
Gauldie, J.1
Jordana, M.2
Cox, G.3
-
159
-
-
0023794169
-
Free radical mechanisms in chemical pathogenesis
-
Kehrer, J.P., Mossman, B.T., Sevanian, A., Trush, M.A., and Smith, M.T. Free radical mechanisms in chemical pathogenesis. Toxicol Appl Pharmacol 1988; 95: 349–362.
-
(1988)
Toxicol Appl Pharmacol
, vol.95
, pp. 349-362
-
-
Kehrer, J.P.1
Mossman, B.T.2
Sevanian, A.3
Trush, M.A.4
Smith, M.T.5
-
160
-
-
26444516111
-
Role of inflammation in the development of rat lung tumors in response to chronic particle exposure
-
Driscoll, K.E. Role of inflammation in the development of rat lung tumors in response to chronic particle exposure. Inhal Toxicol 1996; 8: 139–153.
-
(1996)
Inhal Toxicol
, vol.8
, pp. 139-153
-
-
Driscoll, K.E.1
-
161
-
-
0028848644
-
Characterizing mutagenesis in the hprt gene of rat alveolar epithelial cells
-
Driscoll, K.E., Deyo, L.C., Howard, B.W., Poynter, J., and Carter, J.M. Characterizing mutagenesis in the hprt gene of rat alveolar epithelial cells. Exp Lung Res 1995; 21: 941–956.
-
(1995)
Exp Lung Res
, vol.21
, pp. 941-956
-
-
Driscoll, K.E.1
Deyo, L.C.2
Howard, B.W.3
Poynter, J.4
Carter, J.M.5
-
162
-
-
5744253379
-
Effect of exposure mode on amounts of radiolabeled cigarette particles in lungs and gastrointestinal tracts of F344 rats
-
Chen, B.T., Benz, J.V., Finch, G.L., Mauderly, J.L., Sabourin, P.J., Yeh, H.C., and Snipes, M.B. Effect of exposure mode on amounts of radiolabeled cigarette particles in lungs and gastrointestinal tracts of F344 rats. Inhal Toxicol 1995; 7: 1095–1108.
-
(1995)
Inhal Toxicol
, vol.7
, pp. 1095-1108
-
-
Chen, B.T.1
Benz, J.V.2
Finch, G.L.3
Mauderly, J.L.4
Sabourin, P.J.5
Yeh, H.C.6
Snipes, M.B.7
-
163
-
-
0036151429
-
Mechanisms of genotoxicity of particles and fibers
-
Schins, R.P.F. Mechanisms of genotoxicity of particles and fibers. Inhal Toxicol 2002; 14: 57–78.
-
(2002)
Inhal Toxicol
, vol.14
, pp. 57-78
-
-
Schins, R.P.F.1
-
164
-
-
0022809670
-
Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair
-
Kasai, H., Crain, P.F., Kuchino, Y., Nishimura, S., Octsuyama, A., and Tanocka, H. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis 1986; 7: 1849–1851.
-
(1986)
Carcinogenesis
, vol.7
, pp. 1849-1851
-
-
Kasai, H.1
Crain, P.F.2
Kuchino, Y.3
Nishimura, S.4
Octsuyama, A.5
Tanocka, H.6
-
165
-
-
0023713873
-
Oxidant-induced DNA damage of target cells
-
Schraufstatter, I., Hyslop, P.A., Jackson, J.H., and Cochrane, C.G. Oxidant- induced DNA damage of target cells. J Clin Invest 1988; 82: 1040–1050.
-
(1988)
J Clin Invest
, vol.82
, pp. 1040-1050
-
-
Schraufstatter, I.1
Hyslop, P.A.2
Jackson, J.H.3
Cochrane, C.G.4
-
166
-
-
0024335402
-
Lron ion-dependent modification of bases in DNA by the super-oxide radical-generating system hypoxanthine/xanthine oxidase
-
Aruoma, O.l., Halliwell, B., and Dizdaroglu, N. lron ion-dependent modification of bases in DNA by the super-oxide radical-generating system hypoxanthine/xanthine oxidase. J Biol Chem 1989; 264: 13024–13028.
-
(1989)
J Biol Chem
, vol.264
, pp. 13024-13028
-
-
Aruoma, O.L.1
Halliwell, B.2
Dizdaroglu, N.3
-
167
-
-
0026093495
-
An overview of the relationship between oxidative stress and chemical carcinogenesis
-
Trush, M.A. and Kensler, T.W. An overview of the relationship between oxidative stress and chemical carcinogenesis. Free Radic Biol Med 1991; 10: 201–209.
-
(1991)
Free Radic Biol Med
, vol.10
, pp. 201-209
-
-
Trush, M.A.1
Kensler, T.W.2
-
168
-
-
0023792883
-
Kinetics of the bronchoalveolar leukocyte response in rats during exposure to equal airborne mass concentrations of quartz, chrysoltile asbestos or titanium dioxide
-
Donaldson, K., Bolton, R.E., Jones, A.D., Brown, G.M., Robertson, M.D., Slight, J., Cowie, H., and Davis, J.M.G. Kinetics of the bronchoalveolar leukocyte response in rats during exposure to equal airborne mass concentrations of quartz, chrysoltile asbestos or titanium dioxide. Thorax 1988; 43: 525–533.
-
(1988)
Thorax
, vol.43
, pp. 525-533
-
-
Donaldson, K.1
Bolton, R.E.2
Jones, A.D.3
Brown, G.M.4
Robertson, M.D.5
Slight, J.6
Cowie, H.7
Davis, J.M.G.8
-
169
-
-
0025168671
-
Contrasting bronchoalveolar leukocyte responses in rats inhaling coal mine dust, quartz, or titanium dioxide: Effects of coal rank, airborne mass concentration, and cessation of exposure
-
Donaldson, K., Brown, G.M., Brown, D.M., Robertson, M.D., Slight, J., Cowie, H., Jones, A.D., Bolton, R.E., and Davis, J.M.G. Contrasting bronchoalveolar leukocyte responses in rats inhaling coal mine dust, quartz, or titanium dioxide: Effects of coal rank, airborne mass concentration, and cessation of exposure. Environ Res 1990; 52: 62–76.
-
(1990)
Environ Res
, vol.52
, pp. 62-76
-
-
Donaldson, K.1
Brown, G.M.2
Brown, D.M.3
Robertson, M.D.4
Slight, J.5
Cowie, H.6
Jones, A.D.7
Bolton, R.E.8
Davis, J.M.G.9
-
170
-
-
0025408909
-
Pulmonary response to silica or titanium dioxide: Inflammatory cells, alveolar macrophage-derived cytokines, and histopathology
-
Driscoll, K.E., Lindenschmidt, R.C., Maurer, J.K., Higgins, J.M., and Ridder, G. Pulmonary response to silica or titanium dioxide: inflammatory cells, alveolar macrophage-derived cytokines, and histopathology. Am J Respir Cell Mol Biol 1990; 2: 381–390.
-
(1990)
Am J Respir Cell Mol Biol
, vol.2
, pp. 381-390
-
-
Driscoll, K.E.1
Lindenschmidt, R.C.2
Maurer, J.K.3
Higgins, J.M.4
Ridder, G.5
-
171
-
-
0034816989
-
Toxicity of fibers and particles—report of the workshop held in munich
-
Germany, October 26–27, 2000
-
Greim, H., Borm, P., Schins, R., Donaldson, K., Driscoll, K., Hartwig, A., Kuempel, E., Oberdorster, G., and Speit, G. Toxicity of fibers and particles—Report of the workshop held in Munich, Germany, October 26–27, 2000. Inhal Toxicol 2001; 13: 737–754.
-
(2001)
Inhal Toxicol
, vol.13
, pp. 737-754
-
-
Greim, H.1
Borm, P.2
Schins, R.3
Donaldson, K.4
Driscoll, K.5
Hartwig, A.6
Kuempel, E.7
Oberdorster, G.8
Speit, G.9
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