Short- and intermediate-term carcinogenicity testing - A review Part 2: Available experimental models

Food and Chemical Toxicology

Volumn 36, Issue 11, 1998, Pages 997-1013

  Enzmann, H ^a   Iatropoulos, M ^b   Brunnemann, K D ^b   Bomhard, E ^a   Ahr, H J ^a   Schlueter, G ^a   Williams, G M ^b  

^a BAYER AG   (Germany)

^b AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

ABA=accelerated bioassay; BaP=benzo a pyrene; Carcinogenicity; Colon; CRB=chronic rodent bioassay; DPA=Decision Point Approach; Fish; HAL=hyperplastic adenomatous lesions; In ovo; Initiation; Intermediate term; IOCA=in ovo carcinogenicity assay; Kidney; Lung; MNNG=N methyl N' nitro N nitrosoguanidine; MST=mouse skin tumour; NNK=4 (N methyl N nitrosamino) 1 (3 pyridyl) 1 butanone; Pancreas; Promotion; RLF=rat liver foci; Short term; small intestine; Stomach; Transgenic; Urinary bladder; validation

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; BIRD; BLADDER; BREAST; CARCINOGEN TESTING; CARCINOGENICITY; COLON; DRUG SCREENING; EGG; EMBRYO; FISH; HAMSTER; INVERTEBRATE; KIDNEY; LIVER; LUNG; METHODOLOGY; MODEL; MOUSE; MOUTH CAVITY; NONHUMAN; NOSE; PANCREAS; RAT; REVIEW; SALIVARY GLAND; SKIN; SMALL INTESTINE; STANDARDIZATION; STOMACH; TRANSGENIC ANIMAL; VALIDATION PROCESS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARCINOGENICITY TESTS; CARCINOGENS; CHICK EMBRYO; DOSE-RESPONSE RELATIONSHIP, DRUG; FISHES; HUMANS; MICE; NEOPLASMS, EXPERIMENTAL; RATS; REPRODUCIBILITY OF RESULTS; SPECIES SPECIFICITY;

AVES; RODENTIA; VERTEBRATA;

EID: 0032211455     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(98)00064-7     Document Type: Review

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