The effects of phenethyl isothiocyanate, N-acetylcysteine and green tea on tobacco smoke-induced lung tumors in strain A/J mice

Carcinogenesis

Volumn 19, Issue 10, 1998, Pages 1789-1794

  Witschi, Hanspeter ^a   Espiritu, Imelda ^a   Yu, Mang ^a   Willits, Neil H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; ACETYLCYSTEINE; CIGARETTE SMOKE; CORN OIL; PHENETHYL ISOTHIOCYANATE; PLANT EXTRACT; URETHAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; FEMALE; LUNG CARCINOGENESIS; LUNG TUMOR; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TEA; TOBACCO;

ACETYLCYSTEINE; ANIMALS; ANTICARCINOGENIC AGENTS; FEMALE; ISOTHIOCYANATES; LUNG NEOPLASMS; MALE; MICE; PLANTS, TOXIC; SMOKE; TEA; TOBACCO;

EID: 0031710694     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.10.1789     Document Type: Article

References (39)

1. Benner,S.E., Lippman,S.M. and Hong,W.K. (1995) Chemoprevention of lung cancer. Chest, 107, 316S-321S.
2. van Zandwijk,N. (1995) N-Acetylcysteine (NAC) and glutathione (GSH): antioxidant and chemopreventive properties, with special reference to lung cancer. J. Cell Biochem., 22 (suppl.), 24-32.
3. Karp,D.D. (1997) Lung cancer chemoprevention and management of carcinoma in situ. Semin. Oncol., 24, 402-410.
4. Hecht,S.S. (1995) Chemoprevention by isothiocyanates. J. Cell Biochem., 22 (suppl.), 195-209.
5. van Zandwijk,N., Pastorino,U., De Vries,N. and Dalesio,O. (1993) Euroscan: The European Organization for Research and Treatment of Cancer (EORTC): Chemoprevention Study Lung Cancer. Lung Cancer, 9, 351-356.
6. US EPA (1992) Respiratory Health Effects of Passive Smoking: Lung Cancer and Other Disorders, EPA/600/6-90/006F. Office of Health and Environmental Assessment, US EPA, Washington, DC.
7. Smigel,K. (1996) Beta carotene fails to prevent cancer in two major studies; CARET intervention stopped. J. Natl Cancer Inst., 88, 145.
8. Omenn,G.S., Goodman,G.E., Thornquist,M.D. et al. (1996) Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial [see comments]. J. Natl Cancer Inst., 88, 1550-1559.
9. De Luca,L.M. and Ross,S.A. (1996) Beta-carotene increases lung cancer incidence in cigarette smokers. Nutr. Rev., 54, 178-180.
10. Mohr,U. and Reznik,G. (1978) Tobacco carcinogenesis. In Harris,C.C. (ed.) Pathogenesis and Therapy of Lung Cancer. Marcel Dekker, New York, NY, pp. 263-368.
11. Coggins,C.R.E. (1998) A review of the chronic inhalation studies with mainstream cigarette smoke in rats and mice. Toxicol. Pathol., 26, 307-314.
12. Hecht,S.S. (1997) Approaches to chemoprevention of lung cancer based on carcinogens in tobacco smoke. Environ. Health Perspect., 105 (suppl. 4), 955-963.
13. Stoner,G.D., Adam-Rodwell,G. and Morse,M.A. (1993) Lung tumors in strain A mice: application for studies in cancer chemoprevention. J. Cell Biochem., 17F (suppl.), 95-103.
14. Belinsky,S.A., Stefanski,S.A. and Anderson,M.W. (1993) The A/J mouse lung as a model for developing new chemointervention strategies. Cancer Res., 53, 410-416.
15. Wattenberg,L. (1995) Chalcones, myo-inositol and other novel inhibitors of pulmonary carcinogenesis. J. Cell Biochem., 22 (suppl.), 162-168.
16. Witschi,H.P., Espiritu, I, Peake,J.L., Wu,K., Maronpot,R.R. and Pinkerton,K.E. (1997) The carcinogenicity of environmental tobacco smoke. Carcinogenesis, 18, 575-586.
17. Witschi,H.P., Espiritu,I., Maronpot,R.R., Pinkerton,K.E. and Jones,A.D. (1997) The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis, 18, 2035-2042.
18. Gray,R.H., Adam-Rodwell,G.A., Maris,D., Haskins,J.R. and Stoner,G.D. (1995) Quantitative microscopy of hepatic changes induced by phenethyl isothiocyanate in Fischer-344 rats fed either a cereal-based diet or a purified diet. Toxicol. Pathol., 23, 644-652.
19. Cao,J., Xu,J., Chen,J. and Klaunig,J.E. (1996) Chemopreventive effects of green and black tea on pulmonary and hepatic carcinogenesis. Fundam. Appl. Toxicol., 29, 244-250.
20. De Flora,S., Astengo,M., Serra,D. and Bennicelli,C. (1986) Inhibition of urethan-induced lung tumors in mice by dietary N-acetylcysteine. Cancer Lett., 32, 235-241.
21. Morse,M.A., Eklind,K.I., Hecht,S.S., Jordan,K.G., Choi,C.I., Desai,D.H., Amin,S.G. and Chung,F.L. (1991) Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res., 51, 1846-1850.
22. Morse,M.A., Reinhardt,J.C., Amin,S.G., Hecht,S.S., Stoner,G.D. and Chung,F.L. (1990) Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice. Cancer Lett., 49, 225-230.
23. Teague,S.V., Pinkerton,K.E., Goldsmith,M., Gebremichael,A., Chang,S., Jenkins,R.A. and Moneyhun,J.H. (1994) Sidestream cigarette smoke generation and exposure system for environmental tobacco smoke studies. Inhalation Toxicol., 6, 79-93.
24. Witschi,H.P., Oreffo,V.I.C. and Pinkerton,K.E. (1995) Six month exposure of strain A/J mice to cigarette sidestream smoke: cell kinetics and lung tumor data. Fundam. Appl. Toxicol., 26, 32-40.
25. Witschi,H.P. (1998) Tobacco smoke as a mouse lung carcinogen. Exp. Lung Res., 24, 385-394.
26. Stoner,G.D. and Shimkin,M.B. (1985) Lung tumors in strain A mice as a bioassay for carcinogenicity. In Milman,H. and Weisburger,E.K. (eds.) Handbook of Carcinogen Testing. Noyes Publications, Park Ridge, NJ, pp. 179-214.
27. 6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. Cancer Res., 49, 2894-2897.
28. Hecht,S.S., Morse,M.A., Eklind,K.I. and Chung,F.L. (1991) A/J mouse lung tumorigenesis by the tobacco-specific nitrosamine 4-(methylnitros-amino)-1-(3-pyridyl)-1-butanone and its inhibition by arylalkyl isothiocyanates. Exp. Lung Res., 17, 501-511.
29. Morse,M.A., Eklind,K.I., Amin,S.G. and Chung,F.L. (1992) Effect of frequency of isothiocyanate administration on inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary adenoma formation in A/J mice. Cancer Lett., 62, 77-81.
30. De Flora,S., Cesarone,C.F., Balansky,R.M., Albini,A., D'Agostini,F., Bennicelli,C., Bagnasco,M., Camoirano,A., Scatolini,L. and Rovida,A. (1995) Chemopreventive properties and mechanisms of N-acetylcysteine. The experimental background. J. Cell Biochem., 22 (suppl.), 33-41.
31. Wang,Z.Y., Hong,J.Y., Huang,M.T., Reuhl,K.R., Conney,A.H. and Yang,C.S. (1992) Inhibition of N-nitrosodiethylamine-and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mice by green tea and black tea. Cancer Res., 52, 1943-1947.
32. Lu,Y.P., Lou,Y.R., Xie,J.G., Yen,P., Huang,M.T. and Conney,A.H. (1997) Inhibitory effect of black tea on the growth of established skin tumors in mice: effects on tumor size, apoptosis, mitosis and bromodeoxyuridine incorporation into DNA. Carcinogenesis, 18, 2163-2169.
33. Church,D.W. and Pryor,W.A. (1991) The oxidative stress placed on the lung by cigarette smoke. In Crystal,R.G. and West,J.B. (eds.) The Lung. Scientific Foundations. Raven Press, New York, NY, pp. 1975-1979.
34. Leuchtenberger,C. and Leuchtenberger,R. (1974) Differential response of Snell's and C57 black mice to chronic inhalation of cigarette smoke. Pulmonary carcinogenesis and vascular alterations in lung and heart. Oncology, 29, 122-138.
35. Balansky,R.B., D'Agostini,F., Zanacchi,P. and De Flora,S. (1992) Protection by N-acetylcysteine of the histopathological and cytogenetical damage produced by exposure of rats to cigarette smoke. Cancer Lett., 64, 123-131.
36. Izzotti,A., Balansky,R., Scatolini,L., Rovida,A. and De Flora,S. (1995) Inhibition by N-acetylcysteine of carcinogen-DNA adducts in the tracheal epithelium of rats exposed to cigarette smoke. Carcinogenesis, 16, 669-672.
37. Izzotti,A., Balansky,R.M., Coscia,N., Scatolini,L., D'Agostini,F. and De Flora,S. (1992) Chemoprevention of smoke-related DNA adduct formation in rat lung and heart. Carcinogenesis, 13, 2187-2190.
38. Izzotti,A., Camoirano,A., D'Agostini,F., Sciacca,S., De Naro Papa,F., Cesarone,C.F. and De Flora,S. (1996) Biomarker alterations produced in rat lung by intratracheal instillations of air paniculate extracts and Chemoprevention with oral N-acetylcysteine. Cancer Res., 56, 1533-1538.
39. el-Bayoumy,K., Upadhyaya,P., Desai,D.H., Amin,S., Hoffmann,D. and Wynder,E.L. (1996) Effects of 1,4-phenylenebis(methylene)selenocyanate, phenethyl isothiocyanate, indole-3-carbinol, and d-limonene individually and in combination on the tumorigenicity of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. Anticancer Res., 16, 2709-2712.