Short-term in vitro and in vivo analyses for assessing the tumor-promoting potentials of cigarette smoke condensates

Toxicological Sciences

Volumn 81, Issue 1, 2004, Pages 14-25

  Curtin, Geoffrey M ^a   Hanausek, Margaret ^b   Walaszek, Zbigniew ^b   Mosberg, Arnold T ^a   Slaga, Thomas J ^b  

^a R J REYNOLDS TOBACCO COMPANY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Inflammation; Short term analyses; Sustained epidermal hyperplasia; Tumor promotion

Indexed keywords

ADENOSINE TRIPHOSPHATE; CIGARETTE SMOKE CONDENSATE; CYTOCHROME C; DNA BASE; FREE RADICAL; MYELOPEROXIDASE; SALICYLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; CELL PROLIFERATION; CLINICAL PROTOCOL; CONTROLLED STUDY; CYTOTOXICITY; DNA MODIFICATION; DOSE RESPONSE; ENZYME ACTIVITY; EPIDERMIS HYPERPLASIA; FEMALE; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE MIGRATION; MEDICAL ASSESSMENT; MOUSE; NONHUMAN; ONCOGENE H RAS; SKIN CARCINOGENESIS; SKIN INFLAMMATION; SKIN TUMOR; SKINFOLD THICKNESS; STATISTICAL SIGNIFICANCE; TUMOR PROMOTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BODY WEIGHT; CARCINOGENICITY TESTS; CARCINOGENS; CELL PROLIFERATION; CYTOCHROMES C; DNA ADDUCTS; GENES, RAS; HYDROXYL RADICAL; HYPERPLASIA; INFLAMMATION; LEUKOCYTES; LUMINESCENT MEASUREMENTS; MICE; MICE, INBRED SENCAR; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXIDASE; SALICYLATES; SKIN; SKIN NEOPLASMS; SMOKE; SUPEROXIDES;

NICOTIANA TABACUM;

EID: 4444304726     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh172     Document Type: Article

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