Metallothionein and apoptosis in primary human hepatocellular carcinoma and metastatic adenocarcinoma

Histopathology

Volumn 32, Issue 4, 1998, Pages 340-347

  Deng, D X ^a   Chakrabarti, S ^a   Waalkes, M P ^b   Cherian, M G ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Adenocarcinoma; Apoptosis; Metallothionein; Metastasis; Primary hepatocellular carcinoma

Indexed keywords

METALLOTHIONEIN;

ADENOCARCINOMA; APOPTOSIS; ARTICLE; CELL PROLIFERATION; ENZYME INDUCTION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER METASTASIS; PRIORITY JOURNAL;

ADENOCARCINOMA; ADULT; AGED; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MALE; METALLOTHIONEIN; MIDDLE AGED;

EID: 0031954785     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.1998.00348.x     Document Type: Article

References (43)

1. Cherian MG. Metallothionein and its interaction with Metals. In Goyer RA and Cherian MG eds. Toxicology of Metals Biochemical Aspects. Berlin, Heidelberg: Springer-Verlag Inc., 1995; 121-132.
2. Chan HM, Cherian MG. Ontogenic changes in hepatic metallothionein isoforms in prenatal and newborn rats. Biochem. Cell. Biol. 1993; 71; 133-140.
3. Panemangalore M, Banerjee D, Onosaka S, Cherian MG. Changes in the intracellular accumulation and distribution of metallothionein in rat liver and kidney during postnatal development. Dev. Biol. 1983; 97; 95-102.
4. Masters BA, Kelly EJ, Quaife CJ, Brinster RL, Palmiter RD. Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc. Natl. Acad. Sci. USA 1994; 91; 584-588.
5. Michalska AE, Choo KH. Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc. Natl. Acad. Sci. USA 1993; 90; 8088-8092.
6. Sato M, Bremner I. Oxygen free radicals and metallothionein. Free. Radic. Biol. Med. 1993; 14; 325-337.
7. Nartey N, Cherian MG, Banerjee D. Immunohistochemical localization of metallothionein in human thyroid tumours. Am. J. Pathol. 1987; 129; 177-182.
8. Kontozoglou TE, Banerjee D, Cherian MG. Immunohistochemical localization of metallothionein in human testicular embryonal carcinoma cells. Archiv. A. Pathol. Anat. 1989; 415; 545-549.
9. Chin JL, Banerjee D, Kadhim SA, Kontozoglou TE, Chauvin PJ, Cherian MG. Metallothioneinin testicular germ cell tumours and drug resistance. Cancer 1993; 72; 3029-3035.
10. Bahnson RR, Banner BF, Ernstoff MS et al. Immunohistochemical localization of metallothionein in transitional cell carcinoma of the bladder. J. Urol. 1991; 46; 1518-1520.
11. Chauvin PJ, Cherian MG, Wysocki GP, Pringle GA. A comparison of metallothionein expression in human normal and neoplastic salivary gland tissue using immunohistochemistry. The Toxicologist 1992; 12; 379.
12. Haerslev T, Jakobsen K, Nedergaard L et al. Immunohistochemical detection of metallothionein in primary breast carcinomas and their axillary lymph node metastases. Pathol. Res. Pract. 1994; 190; 675-681.
13. Oyama T, Take H, Hikino T, lino Y, Nakajima T. Immunohisto-chemical expression of metallothionein in invasive breast cancer in relation to proliferative activity. histology and prognosis. Oncology 1996; 53; 112-117.
14. Goulding H, Jasani B, Pereira H et al. Metallothionein expression in human breast cancer. Br. J. Cancer 1995; 72; 968-972.
15. Douglas-Jones AG, Sehmid KW, Bier B et al. Metallothionein expression in duct carcinoma in situ of the breast. Human Pathol. 1995; 26; 217-222.
16. Haerslev T. Jacobsen GK, Zodeler K. The prognostic significance of immunohistochemically detectable metallothionein in primary breast carcinomas. APMIS 1995; 103; 279-285.
17. Bier B, Douglas-Jones A, Totsch M et al. Immunohistochemical demonstration of metallothionein in normal human breast tissue and benign and malignant breast lesions. Breast Cancer Res. Treat. 1994; 30; 213-221.
18. Zelger B, Hittmair A, Schir M et al. Immunohistochemically demonstrated metallothionein expression in malignant melanoma. Histopathology 1993; 23; 257-264.
19. Ohshio G, Imamura T, Okada N et al. Immunohistochemical study of metallothionein in pancreatic carcinomas. J. Cancer Res. Clin. Oncol. 1996; 122; 351-355.
20. Giuffre G, Barresi G, Sturniolo GC, Sarnelli R, Inca RD, Tuccari G. Immunohistochemical expression of metallothionein in normal human colorectal mucosa. in adenomas, and in adenocarcinomas and their associated metastases. Histopathology 1996; 29; 347-354.
21. Ofner D, Maier H, Riedmann B et al. Immunohistochemical metallothionein expression in colorectal adenocarcinoma: correlation with tumor stage and patient survival. Virchows Arch. 1994; 425; 491-497.
22. Cherian MG. The significance of the nuclear and cytoplasmic localization of metallothionein in human liver and tumour cells. Environ. Health Perspect. 1994; 102; 131-135.
23. Tuccari G, Giuffre G, Barresi G. Immunohistochemical expression of metallothionein in colorectal adenocarcinoma. Virchows. Arch. 1996; 427; 547-548.
24. Mills JJ, Chari RS, Boyer IJ, Gould MN, Jirtle RL. Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol. Cancer Res. 1995; 55; 979-983.
25. Steller H. Mechanisms and genes of cellular suicide. Sci. 1995; 267; 1445-1449.
26. Nicholson DW, Ali A, Thornberry NA et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376; 37-43.
27. White E. Life, death, and the pursuit of apoptosis. Genes Dev. 1996; 10; 1-15.
28. Hockenbery DM, Oltvai Zn Yin XM et al. Bcl-2 functions in an anti-oxidant pathway to prevent tumour. Cell 1993; 75; 241-251.
29. Lazo JS, Schwarz MA, Pitt BR. Metallothionein and cell death. In Collery PH, Poirier LA, Littlefield NA, Etienne JC eds. Metal Ions in Biology and Medicine. Paris: John Libbey Eurotext, 1994; 15-16b.
30. Sunderman FW Jr. The influence of zine on apoptosis. Ann. Clin. Lab. Sci. 1995; 25; 134-142.
31. McCabe MJ JR, Jiang SA, Orrenius S. Chelation of intracellular zinc triggers apoptosis in mature thymocytes. Lab. Invest. 1993; 69; 101-110.
32. Oberhammer F, Wilson JW, Dive C et al. Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 Kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 1993; 12; 3679-3684.
33. Cai L, Koropatnick J, Cherian MG. Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitro. Chem. Biol. Internet. 1995; 96; 143-155.
34. Nartey NO, Banerjee D, Cherian MG. Immunohistochemical localization of metallothionein in cell nucleus and cytoplasm of fetal human liver and kidney and its changes during development. Pathology 1987; 19; 233-228.
35. McCarty KS Jr, Miller LS, Cox EB, Konrath J, McCarty KS Sr. Estrogen Receptor Analyses: Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies. Arch. Pathol. Lab. Med. 1985; 109; 716-721.
36. Ansari B, Coates PJ, Creenstein BD et al. In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states. J. Pathol. 1993; 170; 1-8.
37. Onosaka S, Min KS, Fukuhara C et al. Concentrations of metallothionein and metals in malignant and non-malignant tissues in human liver. Toxicology 1986; 38; 261-268.
38. Waalkes MP, Diwan BA. Weghorst CM et al. Further evidence of the tumor-suppressive effects of cadmium in the B6C3F1 mouse liver and lung: late stage vulnerability of tumours to cadmium and the role of metallothionein. J. Pharmacol. Exp. Ther. 1993; 266; 1656-1663.
39. Waalkes MP, Diwan BA, Rehm S et al. Down-regulation of metallothionein expression in human and murine hepatocellular tumours: association with the tumour-necrotizing and antineo-plastic effects of cadmium in mice. J. Pharmacol. Exp. Ther. 1996; 277; 1026-1033.
40. Koropatnick J, Pearson J. Zinc treatment. metallothionein expression and resistance to cisplatin in mouse melanoma cells. Somat. Cell. Mol. Genet. 1990; 16; 529-537.
41. Yin XM, Oltvai ZN, Korsmeyer SJ. BH1 and BH2 domains of bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 1994; 369; 321-323.
42. Yin XM, Oltvai ZN, Veis-Novack DJ et al. Bcl-2 gene family and the regulation of programmed cell death. Cold Spring Harb. Symp. Quant. Biol. 1994; 59; 387-393.
43. Chubatsu LS, Meneghim R. Metallothionein protects DNA from oxidative damage. Biochem. J. 1993; 291; 193-198.