-
1
-
-
0030741841
-
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin
-
O'Brien, T. G., Megosh, L. C., Gilliard, G., and Peralta Soler, A. Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin. Cancer Res., 57: 2630-2637, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 2630-2637
-
-
O'Brien, T.G.1
Megosh, L.C.2
Gilliard, G.3
Peralta Soler, A.4
-
2
-
-
0016801279
-
Induction of the polyamine biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion
-
O'Brien, T. G., Simsiman, R. C., and Boutwell, R. K. Induction of the polyamine biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion. Cancer Res., 35: 2426-2433, 1975.
-
(1975)
Cancer Res.
, vol.35
, pp. 2426-2433
-
-
O'Brien, T.G.1
Simsiman, R.C.2
Boutwell, R.K.3
-
3
-
-
0022445785
-
Effect of application frequency on epidermal omithine decarboxylase induction by chrysarobin in SENCAR mice
-
Kruszewski, R. H., Chenicek, K. J., and DiGiovanni, J. Effect of application frequency on epidermal omithine decarboxylase induction by chrysarobin in SENCAR mice. Cancer Lett., 32: 263-269, 1986.
-
(1986)
Cancer Lett.
, vol.32
, pp. 263-269
-
-
Kruszewski, R.H.1
Chenicek, K.J.2
DiGiovanni, J.3
-
4
-
-
0025820804
-
Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas
-
Lond.
-
Koza, R. A., Megosh, L. C., Palmieri, M., and O'Brien, T. G. Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas. Carcinogenesis (Lond.), 12: 1619-1625, 1991.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1619-1625
-
-
Koza, R.A.1
Megosh, L.C.2
Palmieri, M.3
O'Brien, T.G.4
-
5
-
-
0023709260
-
Presence of a functionally altered ornithine decarboxylase activity in chrysarobin-promoted mouse epidermal papillomas
-
Lond.
-
O'Brien, T. G., O'Donnell, K., Kruszewski, F. H., and DiGiovanni, J. Presence of a functionally altered ornithine decarboxylase activity in chrysarobin-promoted mouse epidermal papillomas. Carcinogenesis (Lond.), 9: 2081-2085, 1988.
-
(1988)
Carcinogenesis
, vol.9
, pp. 2081-2085
-
-
O'Brien, T.G.1
O'Donnell, K.2
Kruszewski, F.H.3
DiGiovanni, J.4
-
6
-
-
0004713598
-
Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C. 4.1.1.17) by substrate and produce analogues
-
Metcalf, R., Bey, P., Danzin, C., Jung, M. J., Casara, P., and Vevert, J. P. Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C. 4.1.1.17) by substrate and produce analogues. J. Am. Chem. Soc., 100: 2551-2553, 1978.
-
(1978)
J. Am. Chem. Soc.
, vol.100
, pp. 2551-2553
-
-
Metcalf, R.1
Bey, P.2
Danzin, C.3
Jung, M.J.4
Casara, P.5
Vevert, J.P.6
-
7
-
-
0029883123
-
Modulation of murine hair follicle function by alterations in ornithine decarboxylase activity
-
Peralta Soler, A., Gilliard, G., Megosh, L. C., and O'Brien, T. G. Modulation of murine hair follicle function by alterations in ornithine decarboxylase activity. J. Invest. Dermatol., 106: 1108-1113, 1996.
-
(1996)
J. Invest. Dermatol.
, vol.106
, pp. 1108-1113
-
-
Peralta Soler, A.1
Gilliard, G.2
Megosh, L.C.3
O'Brien, T.G.4
-
8
-
-
0023485265
-
Inhibition of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis by α-difluoromethylornithine
-
Homma, Y., Kakizoe, T., Samma, S., and Oyasu, R. Inhibition of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis by α-difluoromethylornithine. Cancer Res., 47: 6176-6179, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 6176-6179
-
-
Homma, Y.1
Kakizoe, T.2
Samma, S.3
Oyasu, R.4
-
9
-
-
0020611569
-
Inhibition of ornithine decarboxylase with 2-difluoromethylornithine: Reduced incidence of dimethylhydrazine-induced colon tumors in mice
-
Kingsworth, A. N., King, W. W. K., Diekema, K. A., McCann, P. P., Ross, J. S., and Malt, R. A. Inhibition of ornithine decarboxylase with 2-difluoromethylornithine: reduced incidence of dimethylhydrazine-induced colon tumors in mice. Cancer Res., 43: 2545-2549, 1983.
-
(1983)
Cancer Res.
, vol.43
, pp. 2545-2549
-
-
Kingsworth, A.N.1
King, W.W.K.2
Diekema, K.A.3
McCann, P.P.4
Ross, J.S.5
Malt, R.A.6
-
10
-
-
0021732215
-
Effect of D,L-α-difluoromethylornithine on murine mammary carcinogenesis
-
Lond.
-
Thompson, H. J., Herbst, E. J., Meeker, L. D., Minocha, R., Ronan, A. M., and Fite, R. Effect of D,L-α-difluoromethylornithine on murine mammary carcinogenesis. Carcinogenesis (Lond.), 5: 1649-1651, 1984.
-
(1984)
Carcinogenesis
, vol.5
, pp. 1649-1651
-
-
Thompson, H.J.1
Herbst, E.J.2
Meeker, L.D.3
Minocha, R.4
Ronan, A.M.5
Fite, R.6
-
11
-
-
0020372815
-
Polyamine biosynthesis and skin tumor promotion: Inhibition of 12-O-tetradecanoyl-phorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase α-difluoromethylornithine
-
Takigawa, M., Verma, A. K., Simsiman, R. C., and Boutwell, R. K. Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoyl-phorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase α-difluoromethylornithine. Biochem. Biophys. Res. Commun., 105: 969-976, 1982.
-
(1982)
Biochem. Biophys. Res. Commun.
, vol.105
, pp. 969-976
-
-
Takigawa, M.1
Verma, A.K.2
Simsiman, R.C.3
Boutwell, R.K.4
-
12
-
-
0023269034
-
Increased survival of CD1 mice bearing dimethylhydrazine induced primary colon and anal cancers by difluoromethylornithine with concomittant increase in angiosarcoma incidence
-
Benrezzak, O., Nigam, V. N., and Madarnas, P. Increased survival of CD1 mice bearing dimethylhydrazine induced primary colon and anal cancers by difluoromethylornithine with concomittant increase in angiosarcoma incidence. Anticancer Res., 7: 251-258, 1987.
-
(1987)
Anticancer Res.
, vol.7
, pp. 251-258
-
-
Benrezzak, O.1
Nigam, V.N.2
Madarnas, P.3
-
13
-
-
0023554317
-
Combination therapy using polyamine synthesis inhibitor α-difluoromethylornithine and Adriamycin in treatment of rats carrying the Dunning R3327 MAT-LyLu prostatic adenocarcinoma
-
Shaw, M. W., Guinan, P. D., McKiel, C. F., Dubin, A., and Rubenstein, M. Combination therapy using polyamine synthesis inhibitor α-difluoromethylornithine and Adriamycin in treatment of rats carrying the Dunning R3327 MAT-LyLu prostatic adenocarcinoma. Prostate, 11: 87-93, 1987.
-
(1987)
Prostate
, vol.11
, pp. 87-93
-
-
Shaw, M.W.1
Guinan, P.D.2
McKiel, C.F.3
Dubin, A.4
Rubenstein, M.5
-
14
-
-
0025311468
-
Evaluation of continuous-infusion α-difluoromethylornithine therapy for colorectal carcinoma
-
Ajani, J. A., Ota, D. M., Grossie, V. B., Jr., Abbruzzese, J. L., Faintuch, J. S., Patt, Y. Z., Jackson, D. E., Levin, B., and Nishioka, K. Evaluation of continuous-infusion α-difluoromethylornithine therapy for colorectal carcinoma. Cancer Chemother. Pharmacol., 26: 223-226, 1990.
-
(1990)
Cancer Chemother. Pharmacol.
, vol.26
, pp. 223-226
-
-
Ajani, J.A.1
Ota, D.M.2
Grossie Jr., V.B.3
Abbruzzese, J.L.4
Faintuch, J.S.5
Patt, Y.Z.6
Jackson, D.E.7
Levin, B.8
Nishioka, K.9
-
15
-
-
0029050287
-
Increased frequency of spontaneous skin tumors in transgenic mice which overexpress omithine decarboxylase
-
Megosh, L., Gilmour, S. K., Rosson, D., Peralta Soler, A., Blessing, M., Sawicki, J. A., and O'Brien, T. G. Increased frequency of spontaneous skin tumors in transgenic mice which overexpress omithine decarboxylase. Cancer Res., 55: 4205-4209, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4205-4209
-
-
Megosh, L.1
Gilmour, S.K.2
Rosson, D.3
Peralta Soler, A.4
Blessing, M.5
Sawicki, J.A.6
O'Brien, T.G.7
-
16
-
-
0017672876
-
Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters
-
O'Brien, T. G., and Diamond, L. Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters. Cancer Res., 37: 3895-3900, 1977.
-
(1977)
Cancer Res.
, vol.37
, pp. 3895-3900
-
-
O'Brien, T.G.1
Diamond, L.2
-
17
-
-
0017072855
-
The induction of ornithine decarboxylase as an early, possibly obligatory event in mouse skin carcinogenesis
-
O'Brien, T. G. The induction of ornithine decarboxylase as an early, possibly obligatory event in mouse skin carcinogenesis. Cancer Res., 36: 2644-2653, 1976.
-
(1976)
Cancer Res.
, vol.36
, pp. 2644-2653
-
-
O'Brien, T.G.1
-
18
-
-
0000382583
-
α-Difluoromethylornithine, an irreversible inhibitor of omithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin
-
Weeks, C. E., Herrmann, A. L., Nelson, F. R., and Slaga, T. J. α-Difluoromethylornithine, an irreversible inhibitor of omithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin. Proc. Natl. Acad. Sci. USA, 79: 6028-6032, 1982.
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 6028-6032
-
-
Weeks, C.E.1
Herrmann, A.L.2
Nelson, F.R.3
Slaga, T.J.4
-
19
-
-
0025041030
-
Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter
-
Bailleul, B., Surani, M. A., White, S., Barton, S. C., Brown, K., Blessing, M., Jorcano, J., and Balmain, A. Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter. Cell, 62: 697-708, 1990.
-
(1990)
Cell
, vol.62
, pp. 697-708
-
-
Bailleul, B.1
Surani, M.A.2
White, S.3
Barton, S.C.4
Brown, K.5
Blessing, M.6
Jorcano, J.7
Balmain, A.8
-
20
-
-
0027478822
-
Transgenic mice as a model to study the role of TGF-β-related molecules in hair follicles
-
Blessing, M., Nanney, L. B., King, L. E., Jones, C. M., and Hogan, B. L. M. Transgenic mice as a model to study the role of TGF-β-related molecules in hair follicles. Genes Dev., 7: 204-215, 1992.
-
(1992)
Genes Dev.
, vol.7
, pp. 204-215
-
-
Blessing, M.1
Nanney, L.B.2
King, L.E.3
Jones, C.M.4
Hogan, B.L.M.5
-
21
-
-
0000425845
-
Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
-
Vassar, R., Rosenberg, M., Ross, S., Tyner, A., and Fuchs, E. Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc. Natl. Acad. Sci. USA, 86: 1563-1567, 1989.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 1563-1567
-
-
Vassar, R.1
Rosenberg, M.2
Ross, S.3
Tyner, A.4
Fuchs, E.5
-
22
-
-
0020593774
-
Successful treatment with DL-α-difluoromethylornithine in established human small cell variant lung carcinoma implants in athymic mice
-
Luk, G. D., Abeloff, M. D., Griffin, C. A., and Baylin, S. B. Successful treatment with DL-α-difluoromethylornithine in established human small cell variant lung carcinoma implants in athymic mice. Cancer Res., 43: 4239-4243, 1983.
-
(1983)
Cancer Res.
, vol.43
, pp. 4239-4243
-
-
Luk, G.D.1
Abeloff, M.D.2
Griffin, C.A.3
Baylin, S.B.4
-
23
-
-
0023717516
-
α-Difluoromethylornithine-induced inhibition of growth of autochthonous experimental colonic tumors produced by azoxymethane in male F344 rats
-
Zhang, S-Z., Luk, G. D., and Hamilton, S. R. α-Difluoromethylornithine-induced inhibition of growth of autochthonous experimental colonic tumors produced by azoxymethane in male F344 rats. Cancer Res., 48: 6498-6503, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 6498-6503
-
-
Zhang, S.-Z.1
Luk, G.D.2
Hamilton, S.R.3
-
24
-
-
0023943457
-
Inhibition of human gastric adenocarcinoma xenograft growth in nude mice by α-difluoromethylornithine
-
Upp, J. R., Jr., Beauchamp, R. D., Townsend, C. M., Jr., Barranco, S. C., Singh, P., Rajaraman, S., James, E., and Thompson, J. C. Inhibition of human gastric adenocarcinoma xenograft growth in nude mice by α-difluoromethylornithine. Cancer Res., 48: 3265-3269, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 3265-3269
-
-
Upp Jr., J.R.1
Beauchamp, R.D.2
Townsend Jr., C.M.3
Barranco, S.C.4
Singh, P.5
Rajaraman, S.6
James, E.7
Thompson, J.C.8
-
25
-
-
0023881236
-
Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy
-
Pegg, A. E. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res., 48: 759-774, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 759-774
-
-
Pegg, A.E.1
-
26
-
-
0011493380
-
Mutagenesis of the Ha-ras oncogene in mouse skin tumours induced by polycyclic aromatic hydrocarbons
-
Bizub, D., Wood, A. W., and Shalka, A. M. Mutagenesis of the Ha-ras oncogene in mouse skin tumours induced by polycyclic aromatic hydrocarbons. Proc. Natl. Acad. Sci. USA, 83: 6048-6052, 1986.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 6048-6052
-
-
Bizub, D.1
Wood, A.W.2
Shalka, A.M.3
-
27
-
-
0022527161
-
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
-
Quintanilla, M., Brown, K., Ramsden, M., and Balmain, A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature (Lond.), 322: 78-80, 1986.
-
(1986)
Nature (Lond.)
, vol.322
, pp. 78-80
-
-
Quintanilla, M.1
Brown, K.2
Ramsden, M.3
Balmain, A.4
-
29
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakumura, Y., White, R., Smits, A. M. M., and Bos, J. L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 319: 525-532, 1988.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
Nakumura, Y.7
White, R.8
Smits, A.M.M.9
Bos, J.L.10
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