-
2
-
-
0023619575
-
A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants
-
Washington DC
-
Trahy, M , and McCormick, F. A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science (Washington DC), 238: 542-545, 1987.
-
(1987)
Science
, vol.238
, pp. 542-545
-
-
Trahy, M.1
McCormick, F.2
-
3
-
-
0024294392
-
Guanosine triphosphate activating protein (GAP) interacts with the p21 ras effector binding
-
Washington DC
-
Adari, H., Lowy, D. R., Willumsen, B. M., Der, C. J , and McCormick, F. Guanosine triphosphate activating protein (GAP) interacts with the p21 ras effector binding. Science (Washington DC), 240: 518-521, 1988.
-
(1988)
Science
, vol.240
, pp. 518-521
-
-
Adari, H.1
Lowy, D.R.2
Willumsen, B.M.3
Der, C.J.4
McCormick, F.5
-
4
-
-
0024280502
-
The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product
-
Lond.
-
Cales, C., Hancock, J. F., Marshall, C. J., and Hall A. The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product. Nature (Lond.), 332: 548-551, 1988.
-
(1988)
Nature
, vol.332
, pp. 548-551
-
-
Cales, C.1
Hancock, J.F.2
Marshall, C.J.3
Hall, A.4
-
5
-
-
0023681723
-
Cloning of bovine GAP and its interaction with oncogenic ras p21
-
Lond.
-
Vogel, U S., Dixon, R. A. F., Schaber, M. D., Diehl, R. E., Marshall, M. S., Scolnick, E. M., Sigal, I. S., and Gibbs, J. B. Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature (Lond.), 335: 90-93, 1988.
-
(1988)
Nature
, vol.335
, pp. 90-93
-
-
Vogel, U.S.1
Dixon, R.A.F.2
Schaber, M.D.3
Diehl, R.E.4
Marshall, M.S.5
Scolnick, E.M.6
Sigal, I.S.7
Gibbs, J.B.8
-
6
-
-
0024502703
-
ras GTPase activating protein: Signal transmitter and signal terminator
-
McCormick, F. ras GTPase activating protein: signal transmitter and signal terminator. Cell, 56: 5-8, 1989.
-
(1989)
Cell
, vol.56
, pp. 5-8
-
-
McCormick, F.1
-
7
-
-
0023898932
-
The ras gene family and human carcinogenesis
-
Bos, J. L. The ras gene family and human carcinogenesis. Mutat. Res., 195: 255-271, 1988.
-
(1988)
Mutat. Res.
, vol.195
, pp. 255-271
-
-
Bos, J.L.1
-
8
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
Bos, J. L. ras oncogenes in human cancer: a review. Cancer Res., 49: 4682-4689, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
9
-
-
0023707058
-
Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung
-
Rodenhuis, S., Slebos, R. J., Boot, A. J. M., Evers, S. G., Mooi, W. J., Wagenaar, S. S., van Bodegom, P. C., and Bos, I. L. Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung. Cancer Res., 48: 5738-5741, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 5738-5741
-
-
Rodenhuis, S.1
Slebos, R.J.2
Boot, A.J.M.3
Evers, S.G.4
Mooi, W.J.5
Wagenaar, S.S.6
Van Bodegom, P.C.7
Bos, I.L.8
-
10
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancer
-
Lond.
-
Bos, J. L., Fearon, E. R., Hamilton, S. R., Verlaan-de Vries, M., Van Boom, J. H., Van der Eb, E. J., and Vogelstein, B. Prevalence of ras gene mutations in human colorectal cancer. Nature (Lond.), 327: 298-303, 1987.
-
(1987)
Nature
, vol.327
, pp. 298-303
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
Verlaan-de Vries, M.4
Van Boom, J.H.5
Van Der Eb, E.J.6
Vogelstein, B.7
-
11
-
-
0023262990
-
Detection of high incidence of K-ras oncogene during human colon tumorigenesis
-
Lond.
-
Forrester, K., Almoguera, C., Han, K., Grizzle, W. E., and Perucho, M. Detection of high incidence of K-ras oncogene during human colon tumorigenesis. Nature (Lond.), 327: 298-303, 1987.
-
(1987)
Nature
, vol.327
, pp. 298-303
-
-
Forrester, K.1
Almoguera, C.2
Han, K.3
Grizzle, W.E.4
Perucho, M.5
-
12
-
-
0024292722
-
Most of human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
Almoguera, C., Shibata, D., Forrester, K., Martin, J., Arnheim, N., and Perucho, M. Most of human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell, 53: 549-554, 1988.
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, N.5
Perucho, M.6
-
13
-
-
0023735997
-
K-ras codon 12 mutations occur very frequently in pancreas adenocarcinomas
-
Smit, V. T., Boot, A. J. M., Smits, A. M. M., Fleuren, G. J., Cornelisse, C. J., and Bos, J. L. K-ras codon 12 mutations occur very frequently in pancreas adenocarcinomas. Nucleic Acids Res., 16: 7773-7782, 1988.
-
(1988)
Nucleic Acids Res.
, vol.16
, pp. 7773-7782
-
-
Smit, V.T.1
Boot, A.J.M.2
Smits, A.M.M.3
Fleuren, G.J.4
Cornelisse, C.J.5
Bos, J.L.6
-
14
-
-
0006391635
-
Oncogene activation in human breast cancer
-
Cold Spring Harbor
-
Van de Vijver, M. J., Peterse, J. L., Mooi, W. J., Lomans, J., Verbruggen, M., Van de Bersselar, R., Devilee, P., Cornelisse, C., Bos, J. L., Yarnold, J., and Nusse, R. Oncogene activation in human breast cancer Cancer Cells (Cold Spring Harbor), 7: 385-391, 1989.
-
(1989)
Cancer Cells
, vol.7
, pp. 385-391
-
-
Van De Vijver, M.J.1
Peterse, J.L.2
Mooi, W.J.3
Lomans, J.4
Verbruggen, M.5
Van De Bersselar, R.6
Devilee, P.7
Cornelisse, C.8
Bos, J.L.9
Yarnold, J.10
Nusse, R.11
-
15
-
-
0024230919
-
Preferential and novel activation of H-ras in human bladder carcinomas
-
Visvanathan, K. V., Pocock, R. D., and Summerhayes, I. C. Preferential and novel activation of H-ras in human bladder carcinomas. Oncogene Res., 3: 77-86, 1988.
-
(1988)
Oncogene Res.
, vol.3
, pp. 77-86
-
-
Visvanathan, K.V.1
Pocock, R.D.2
Summerhayes, I.C.3
-
16
-
-
0025293818
-
Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products
-
Suzuki, Y., Orita, M., Shiraishi, M., Hayashi, K., and Sekiya, T. Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene, 5: 1037-1043, 1990.
-
(1990)
Oncogene
, vol.5
, pp. 1037-1043
-
-
Suzuki, Y.1
Orita, M.2
Shiraishi, M.3
Hayashi, K.4
Sekiya, T.5
-
17
-
-
0025785811
-
Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines
-
Mitsudomi, T., Viallet, J., Mulshine, J. L., Linnoila, R. I., Minna, J. D., and Gazda, A. F. Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines. Oncogene, 6: 1353-1362, 1991.
-
(1991)
Oncogene
, vol.6
, pp. 1353-1362
-
-
Mitsudomi, T.1
Viallet, J.2
Mulshine, J.L.3
Linnoila, R.I.4
Minna, J.D.5
Gazda, A.F.6
-
18
-
-
0026654238
-
ras gene mutation as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis
-
Sugio, K., Ishida, T., Yokoyama, H., Inoue, T., Sugimachi, K., and Sasazuki, T. ras gene mutation as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis. Cancer Res., 52: 2903-2906, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 2903-2906
-
-
Sugio, K.1
Ishida, T.2
Yokoyama, H.3
Inoue, T.4
Sugimachi, K.5
Sasazuki, T.6
-
19
-
-
0026680448
-
Clinical significance of ras oncogene activation in human lung cancer
-
Rodenhuis, S., and Slebos, R. J. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res., 52 (Suppl.): 2665s-2669s, 1992.
-
(1992)
Cancer Res.
, vol.52
, Issue.SUPPL.
-
-
Rodenhuis, S.1
Slebos, R.J.2
-
20
-
-
0023461268
-
Specific synthesis of DNA synthesis in vitro via a catalyzed polymerase chain reaction
-
Mullis, K. B., and Faloona, F. A. Specific synthesis of DNA synthesis in vitro via a catalyzed polymerase chain reaction. Methods Enzymol., 155: 335-350, 1987.
-
(1987)
Methods Enzymol.
, vol.155
, pp. 335-350
-
-
Mullis, K.B.1
Faloona, F.A.2
-
21
-
-
0023850178
-
Primer-directed enzymatic amplification of DNA with a thermo-stable DNA polymerase
-
Washington DC
-
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. G., Higuchi, R., Horn, G. T., Mullis, K. B., and Erlich, H. A. Primer-directed enzymatic amplification of DNA with a thermo-stable DNA polymerase. Science (Washington DC), 239: 487-491, 1988.
-
(1988)
Science
, vol.239
, pp. 487-491
-
-
Saiki, R.K.1
Gelfand, D.H.2
Stoffel, S.3
Scharf, S.G.4
Higuchi, R.5
Horn, G.T.6
Mullis, K.B.7
Erlich, H.A.8
-
22
-
-
0001430252
-
DNA fragments differing by single base-pair substitutions separated in denaturing gradient gels: Correspondence with melting theory
-
Fischer, S. H., and Lerman, L. S. DNA fragments differing by single base-pair substitutions separated in denaturing gradient gels: correspondence with melting theory. Proc. Natl. Acad Sci. USA, 80: 1579-1583, 1983.
-
(1983)
Proc. Natl. Acad Sci. USA
, vol.80
, pp. 1579-1583
-
-
Fischer, S.H.1
Lerman, L.S.2
-
23
-
-
0026511264
-
Mutational spectrometry: A general approach for hotspot point mutations in selectable genes
-
Keohavong, P., and Thilly, W. G. Mutational spectrometry: a general approach for hotspot point mutations in selectable genes. Proc. Natl. Acad. Sci. USA, 89: 4623-4627, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4623-4627
-
-
Keohavong, P.1
Thilly, W.G.2
-
24
-
-
0000023099
-
Attachment of a 40-base-pair G+C rich sequence to genomic DNA fragments by polymerase chain reaction results in improved detection of single base changes
-
Sheffield, V. C., Cox, D. R., Lerman, L. S., and Myers, R. M. Attachment of a 40-base-pair G+C rich sequence to genomic DNA fragments by polymerase chain reaction results in improved detection of single base changes. Proc. Natl. Acad. Sci. USA, 86: 232-236, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 232-236
-
-
Sheffield, V.C.1
Cox, D.R.2
Lerman, L.S.3
Myers, R.M.4
-
25
-
-
0025042740
-
Molecular analysis of complex human cell population: Mutational spectra of MNNG and ICR-191
-
Cariello, N F., Keohavong, P., Kat, A. G., and Thilly, W. G. Molecular analysis of complex human cell population: mutational spectra of MNNG and ICR-191 Mutat. Res, 231: 165-176, 1990.
-
(1990)
Mutat. Res
, vol.231
, pp. 165-176
-
-
Cariello, N.F.1
Keohavong, P.2
Kat, A.G.3
Thilly, W.G.4
-
26
-
-
0024368667
-
Fidelity of DNA polymerases in DNA amplification
-
Keohavong, P., and Thilly, W. G. Fidelity of DNA polymerases in DNA amplification. Proc. Natl Acad. Sci. USA, 86: 9253-9257, 1989.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 9253-9257
-
-
Keohavong, P.1
Thilly, W.G.2
-
27
-
-
0021126650
-
D Biological properties of human c-H-ras genes mutated at codon 12
-
Lond.
-
Seeburgh, P. H. Colby, W. W., Capon, D. J., Goeddel, D. V., and Levinson, A. D Biological properties of human c-H-ras genes mutated at codon 12. Nature (Lond.), 312: 71-75. 1984.
-
(1984)
Nature
, vol.312
, pp. 71-75
-
-
Seeburgh, P.H.1
Colby, W.W.2
Capon, D.J.3
Goeddel, D.V.4
Levinson, A.5
-
28
-
-
0027407823
-
K-ras mutations in human adenocarcinoma of the lung: Association with smoking and occupational exposure to asbestos
-
Husgafvel-Prusiainen, K., Hackman, P., Ridanpaa, M., Anttila, S., Karjalainen, A., Partanen, T., Taikina-Aho, O., Heikkila, L , and Vaino, H. K-ras mutations in human adenocarcinoma of the lung: association with smoking and occupational exposure to asbestos. Int. J. Cancer, 53: 250-256, 1993.
-
(1993)
Int. J. Cancer
, vol.53
, pp. 250-256
-
-
Husgafvel-Prusiainen, K.1
Hackman, P.2
Ridanpaa, M.3
Anttila, S.4
Karjalainen, A.5
Partanen, T.6
Taikina-Aho, O.7
Heikkila, L.8
Vaino, H.9
-
29
-
-
0025322751
-
Association of point mutation in c-K-ras oncogene in lung adenocarcinoma with particular reference to cytologic subtypes
-
Phila.
-
Kobayashi, T., Tsuda, H., Noguchi, M., Hirohashi, S., Shimosato, Y., Goya, T., and Hayata, Y. Association of point mutation in c-K-ras oncogene in lung adenocarcinoma with particular reference to cytologic subtypes. Cancer (Phila.), 66: 289-294, 1990.
-
(1990)
Cancer
, vol.66
, pp. 289-294
-
-
Kobayashi, T.1
Tsuda, H.2
Noguchi, M.3
Hirohashi, S.4
Shimosato, Y.5
Goya, T.6
Hayata, Y.7
-
30
-
-
0025851146
-
Relationship between K-ras oncogene activation and smoking in adenocarcinoma of the human lung
-
Slebos, R. J. C., Hruban, R. H., Dalesio, O., Mooi, W. J., Offenhaus, G. J. A., and Rodenhuis, S. Relationship between K-ras oncogene activation and smoking in adenocarcinoma of the human lung. J. Natl. Cancer Inst., 83: 1024-1027, 1991
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 1024-1027
-
-
Slebos, R.J.C.1
Hruban, R.H.2
Dalesio, O.3
Mooi, W.J.4
Offenhaus, G.J.A.5
Rodenhuis, S.6
-
31
-
-
0023746566
-
Sequence specificity of mutations induced by benzo(a)pyrene-7,8-diol-9,10-epoxide at endogenous aprt gene in CHO cells
-
Mazur, M., and Glickman, B. W. Sequence specificity of mutations induced by benzo(a)pyrene-7,8-diol-9,10-epoxide at endogenous aprt gene in CHO cells. Somatic Cell Mol. Genet., 14: 393-400, 1988.
-
(1988)
Somatic Cell Mol. Genet.
, vol.14
, pp. 393-400
-
-
Mazur, M.1
Glickman, B.W.2
-
32
-
-
0025152226
-
Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (±)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo(a)pyrene in the coding region of the HPRT gene
-
Chen, R. H., Mahe, R. H , and McCormick, J. J. Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (±)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo(a)pyrene in the coding region of the HPRT gene. Proc. Natl. Acad. Sci USA, 87: 8680-8684, 1990.
-
(1990)
Proc. Natl. Acad. Sci USA
, vol.87
, pp. 8680-8684
-
-
Chen, R.H.1
Mahe, R.H.2
McCormick, J.J.3
-
33
-
-
0024437222
-
Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogenes and lung tumors from A/J mice treated with nitrosamines
-
Belinsky, S. A., Devereux, T. R., Maronpot, R. R., Stoner, G. D., and Anderson, M. W. Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogenes and lung tumors from A/J mice treated with nitrosamines. Cancer Res., 49: 5305-5311, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5305-5311
-
-
Belinsky, S.A.1
Devereux, T.R.2
Maronpot, R.R.3
Stoner, G.D.4
Anderson, M.W.5
-
34
-
-
0023638236
-
Two adjacent mutations at position 12 activate the K-ras 2 oncogene of a human mammary cell line
-
Prosperi, M. T., Even, J., Calvo, F., Lebeau, J., and Goulin, G. Two adjacent mutations at position 12 activate the K-ras 2 oncogene of a human mammary cell line. Oncogene Res., 1: 121-128, 1987.
-
(1987)
Oncogene Res
, vol.1
, pp. 121-128
-
-
Prosperi, M.T.1
Even, J.2
Calvo, F.3
Lebeau, J.4
Goulin, G.5
-
35
-
-
0026425629
-
ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent
-
Mitsudomi, T., Steinberg, S. M., Oie, H. K., Mulshine, J. L., Phelps, R., Viallet, J , Pass, H , Minna, J. D., and Gazda, A. F. ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent. Cancer Res., 51: 4999-5002, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 4999-5002
-
-
Mitsudomi, T.1
Steinberg, S.M.2
Oie, H.K.3
Mulshine, J.L.4
Phelps, R.5
Viallet, J.6
Pass, H.7
Minna, J.D.8
Gazda, A.F.9
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