The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets

Molecular Cell

Volumn 39, Issue 1, 2010, Pages 8-24

  Krishnakumar, Raga ^a   Kraus, W Lee ^a,b  

^a Department of Obstetrics Gynecology   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,5 ISOQUINOLINEDIOL; 2 (2 METHYL 2 PYRROLIDINYL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 3 AMINOBENZAMIDE; DOXORUBICIN; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OLAPARIB; POLY(ADENOSINE DIPHOSPHATE RIBOSE); SIRTUIN 1; UNCLASSIFIED DRUG; XAV 939;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL NUCLEUS; CHROMATIN STRUCTURE; CHROMOSOME STRUCTURE; DNA DAMAGE; DNA METHYLATION; DNA STRUCTURE; DRUG TARGETING; ENZYME ACTIVE SITE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOME IMPRINTING; HUMAN; INFLAMMATION; NONHUMAN; NUCLEOSOME; NUCLEOTIDE METABOLISM; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REVIEW; STEM CELL; SUMOYLATION; UBIQUITINATION;

ANIMALS; CELL NUCLEUS; CLINICAL TRIALS AS TOPIC; DNA; DNA METHYLATION; HUMANS; MODELS, ANIMAL; POLY(ADP-RIBOSE) POLYMERASES;

EID: 77954274504     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.06.017     Document Type: Review

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