Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci

Science

Volumn 299, Issue 5606, 2003, Pages 560-562

  Tulin, Alexei ^a   Spradling, Allan ^a  

^a GEOPHYSICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENES; PHOSPHATES;

STRESS-ACTIVATED GENES;

ENZYMES;

ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE DIPHOSPHATE RIBOSE POLYMERASE; ENZYME; HEAT SHOCK PROTEIN 70; UNCLASSIFIED DRUG;

CHROMOSOME; DNA; GENE;

ARTICLE; CHROMATIN STRUCTURE; CHROMOSOME PUFF; DEVELOPMENTAL STAGE; DROSOPHILA; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; GENE INDUCTION; GENE LOCUS; GENETIC TRANSCRIPTION; LARVA; NONHUMAN; PRIORITY JOURNAL; SALIVARY GLAND; THERMAL EXPOSURE;

ANIMALS; CELL NUCLEUS; CHROMATIN; CHROMOSOMES; DNA; DROSOPHILA; DROSOPHILA PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HEAT-SHOCK RESPONSE; HSP70 HEAT-SHOCK PROTEINS; IMMUNITY, NATURAL; INSECT PROTEINS; MODELS, BIOLOGICAL; MUTATION; NF-KAPPA B; NUCLEOSOMES; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

NEPTUNIA;

EID: 0037462597     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1078764     Document Type: Article

References (13)

1. K. Hagstrom, P. Schedl, Curr. Opin. Genet. Dev. 7, 814 (1997).
2. M. Ziegler, S. L. Oei, Bioessays 23, 543 (2001).
3. A. Tulin, D. Stewart, A. C. Spradling, Genes Dev. 16, 2108 (2002).
4. C. S. Thummel, Insect Biochem. Mol. Biol. 32, 113 (2000).
5. S. Lindquist, Annu. Rev. Biochem. 55, 1151 (1986).
6. CH1 causes a variegated partial expression of the heterochromatic Parp gene (3) in certain tissues, including the larval salivary gland and brain (see Fig. 3B; data not shown).
7. M. Kameoka et al., Biochem. J. 346, 641 (2000).
8. J. A. Hoffmann, M. Reichhart, Nature Immunol. 3, 121 (2002).
9. E. A. Meyerowitz et al., Cold Spring Harbor Symp. 50, 347 (1985).
10. I. L. Cartwright, S. C. R. Elgin, Mol. Cell. Biol. 6, 779 (1986).
11. J. A. Simon, C. A. Sutton, J. T. Lis, Chromosoma 93, 26 (1985).
12. Materials and Methods are available as supporting online material at Science Online.
13. We thank D. Ferrandon, J. Hoffmann, J. Gall, and S. Lindquist for providing materials. T. Murphy and N. Buszczak provided comments on the manuscript. Supported by NIH grant GM27875.