Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development

PLoS ONE

Volumn 3, Issue 7, 2008, Pages

  Chiang, Y Jeffrey ^a   Hsiao, Susan J ^c   Yver, Dena ^d   Cushman, Samuel W ^d   Tessarollo, Lino ^b   Smith, Susan ^c   Hodes, Richard J ^a,e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TANKYRASE; TANKYRASE 1; TANKYRASE 2; GLUCOSE; INSULIN; TANKYRASE 2, MOUSE; TANKYRASE-2, MOUSE; TNKS PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE REGULATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEFICIENCY; FEMALE; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; MOUSE MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; TELOMERE; ANIMAL; EMBRYO (ANATOMY); GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHENOTYPE; PHYSIOLOGY;

MUS;

ANIMALS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOSE; INSULIN; MICE; MICE, KNOCKOUT; PHENOTYPE; TANKYRASES;

EID: 50249090605     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002639     Document Type: Article

References (30)

1. Kuimov AN, Kuprash DV, Petrov VN, Vdovichenko KK, Scanlan MJ, et al. (2001) Cloning and characterization of TNKL, a member of tankyrase gene family. Genes Immun 2: 52-55.
2. Smith S, Giriat I, Schmitt A, de Lange T (l998) Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282: 1484-1487.
3. Sbodio JI, Chi NW (2002) Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner. J Biol Chem 277: 31887-31892.
4. Seimiya H, Smith S (2002) The telomeric poly(ADP-ribose) polymerase, tankyrasc 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182). J Biol Chem 277: 14116-14126.
5. Chang W, Dynek JN, Smith S (2005) NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis. Biochem J 391: 177-184.
6. Hsiao SJ, Poitras MF, Cook BD, Liu Y, Smith S (2006) Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping. Mol Cell Biol 26: 2044-2054.
7. Bhackburn EH (2005) Telomeres and telomerase: their mechanisms of action and the effects of altering their functions. FEBS Lett 579: 859-862.
8. Garcia CK, Wright WE, Shay JW (2007) Human diseases of telomerase dysfunction: insights into tissue aging. Nucleic Acids Res 35: 7406-7416.
9. Autexier C, Lue NF (2006) The structure and function of telomerase reverse transcriptase. Annu Rev Biochem 75: 493-517.
10. Cook BD, Dynek JN, Chang W, Shostak G, Smith S (2002) Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol Cell Biol 22: 332-342.
11. Smith S, de Lange T (2000) Tankyrase promotes telomere elongation in human cells. Curr Biol 10: 1299-1302.
12. Chang P, Coughlin M, Mitchison TJ (2005) Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nat Cell Biol.
13. Dynek JN, Smith S (2004) Resolution of sister telomere association is required for progression through mitosis. Science 304: 97-100.
14. Canudas S, Houghtaling BR, Kim JY, Dynek JN, Chang WG, et al. (2007) Protein requirements for sister telomere association in human cells. Embo J 26: 4867-4878.
15. Yeh TY, Sbodio JI, Tsun ZY, Luo B, Chi NW (2007) Insulin-stimulated exocytosis of GLUT4 is enhanced by IRAP and its partner tankyrase. Biochem J 402: 279-290.
16. Chi NWV, Lodish HF (2000) Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles. J Biol Chem 275: 38437-38444.
17. Sbodio JI, Lodish HF, Chi NW (2002) Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase). Biochem J 361: 451-459.
18. Chiang YJ, Nguyen ML, Gurunathan S, Kaminker P, Tessarollo L, et al. (2006) Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice. Mol Cell Biol 26: 2037-2043.
19. Tessarollo L (2001) Gene Knockouts: Manipulating mouse embryonic stem cells. Methods Mol Biol 158: 47-453.
20. Lakso M, Pichel JG, Gorman JR, Sauer B, Okamoto Y, et al. (1996) Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci U S A 93: 5860-5805.
21. Scherthan H, Jerratsch M, Li B, Smith S, Hulten M, et al. (2000) Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores. Mol Biol Cell 11: 4189-4203.
22. Baerlocher GM, Mak J, Tien T, Lansdorp PM (2002) Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls. Cytometry 47: 89-99.
23. Fritsch RD, Shen X, Sims GP, Hathcock KS, Hodes RJ, et al. (2005) Stepwise differentiation of CD4 memory T cells defined by expression of CCR7 and CD27. J Immunol 175: 6489-6497.
24. Gliemann J, Rees WD, Foley JA (1984) The fate of labelled glucose molecules in the rat adipocyte. Dependence on glucose concentration. Biochim Biophys Acta 804: 68-76.
25. Xu X, Weinstein M, Li C, Naski M, Cohen RI, et al. (1998) Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development 125: 753-765.
26. Chang W, Dynek JN, Smith S (2003) TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres. Genes Dev 17: 1328-1333.
27. Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, et al. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91: 25-34.
28. Chiang YJ, Hemann MT, Hathcock KS, Tessarollo L, Feigenbaum L, et al. (2004) Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo. Mol Cell Biol 24: 7024-7031.
29. Erdmann N, Liu Y, Harrington L (2004) Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice. Proc Natl Acad Sci U S A 101: 6080-6085.
30. Hathcock KS, Jeffrey Ghiang Y, Hodes RJ (2005) In vivo regulation of telomerase activity and telomere length. Immunol Rev 205: 104-113.