메뉴 건너뛰기




Volumn 10, Issue 2, 2010, Pages 109-123

Molecular determinants of the cardiometabolic phenotype

Author keywords

Cardiometabolic syndrome; Dyslipidemia; Hypertension; Inflammation; Insulin resistance; Metabolic syndrome; Obesity; Substrate metabolism

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPOCYTOKINE; ANTIINFLAMMATORY AGENT; C REACTIVE PROTEIN; ETANERCEPT; FATTY ACID; FIBRIC ACID DERIVATIVE; FIBRINOGEN; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLIXIMAB; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OSTEOPONTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECOMBINANT LEPTIN; RIMONABANT; ROSIGLITAZONE; SULFONYLUREA; TELMISARTAN; TRIACYLGLYCEROL; UNINDEXED DRUG;

EID: 77954080527     PISSN: 18715303     EISSN: None     Source Type: Journal    
DOI: 10.2174/187153010791213119     Document Type: Article
Times cited : (4)

References (250)
  • 3
    • 0037126526 scopus 로고    scopus 로고
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). (2002) Circulation, 106, 3143-3421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 4
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome--a new worldwide definition
    • and Group, I.D.F.E.T.F.C
    • Alberti, K.G.; Zimmet, P.; Shaw, J. and Group, I.D.F.E.T.F.C. (2005) The metabolic syndrome--a new worldwide definition. Lancet, 366, 1059-1062.
    • (2005) Lancet , vol.366 , pp. 1059-1062
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 5
    • 0037407403 scopus 로고    scopus 로고
    • NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older
    • Alexander, C.M.; Landsman, P.B.; Teutsch, S.M. and Haffner, S.M. (2003) NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III partici- pants age 50 years and older. Diabetes, 52, 1210-1214.
    • (2003) Diabetes , vol.52 , pp. 1210-1214
    • Alexander, C.M.1    Landsman, P.B.2    Teutsch, S.M.3    Haffner, S.M.4
  • 6
    • 34250866507 scopus 로고    scopus 로고
    • Metabolic syndrome is associated with abnormal left ventricular diastolic function independent of left ventricular mass
    • de las Fuentes, L.; Brown, A.L.; Mathews, S.J.; Waggoner, A.D.; Soto, P.F.; Gropler, R.J. and Davila-Roman, V.G. (2007) Metabolic syndrome is associated with abnormal left ventricular diastolic function independent of left ventricular mass. Eur. Heart J., 28, 553-559.
    • (2007) Eur. Heart J , vol.28 , pp. 553-559
    • de las Fuentes, L.1    Brown, A.L.2    Mathews, S.J.3    Waggoner, A.D.4    Soto, P.F.5    Gropler, R.J.6    Davila-Roman, V.G.7
  • 7
    • 23844443889 scopus 로고    scopus 로고
    • Metabolic syndrome and echocardiographic left ventricular mass in blacks: The Atherosclerosis Risk in Communities (ARIC) Study
    • Burchfiel, C.M.; Skelton, T.N.; Andrew, M.E.; Garrison, R.J.; Arnett, D.K.; Jones, D.W. and Taylor, H.A.Jr. (2005) Metabolic syndrome and echocardiographic left ventricular mass in blacks: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation, 112, 819-827.
    • (2005) Circulation , vol.112 , pp. 819-827
    • Burchfiel, C.M.1    Skelton, T.N.2    Andrew, M.E.3    Garrison, R.J.4    Arnett, D.K.5    Jones, D.W.6    Taylor Jr., H.A.7
  • 9
    • 0031898535 scopus 로고    scopus 로고
    • Is metabolic syndrome a discrete entity in the general population? Evidence from the Caerphilly and Speedwell population studies
    • Yarnell, J.W.; Patterson, C.C.; Bainton, D. and Sweetnam, P.M. (1998) Is metabolic syndrome a discrete entity in the general popu- lation? Evidence from the Caerphilly and Speedwell population studies. Heart, 79, 248-252.
    • (1998) Heart , vol.79 , pp. 248-252
    • Yarnell, J.W.1    Patterson, C.C.2    Bainton, D.3    Sweetnam, P.M.4
  • 11
    • 34447118721 scopus 로고    scopus 로고
    • Prognostic impact of metabolic syndrome by different definitions in a population with high prevalence of obesity and diabetes: The Strong Heart Study
    • de Simone, G.; Devereux, R.B.; Chinali, M.; Best, L.G.; Lee, E.T.; Galloway, J.M.; Resnick, H.E. and Investigators, S.H.S. (2007) Prognostic impact of metabolic syndrome by different definitions in a population with high prevalence of obesity and diabetes: the Strong Heart Study. Diabetes Care, 30, 1851-1856.
    • (2007) Diabetes Care , vol.30 , pp. 1851-1856
    • de Simone, G.1    Devereux, R.B.2    Chinali, M.3    Best, L.G.4    Lee, E.T.5    Galloway, J.M.6    Resnick, H.E.7    Investigators, S.H.S.8
  • 12
    • 4444222221 scopus 로고    scopus 로고
    • Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
    • Malik, S.; Wong, N.D.; Franklin, S.S.; Kamath, T.V.; L'Italien, G.J.; Pio, J.R. and Williams, G.R. (2004) Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation, 110, 1245-1250.
    • (2004) Circulation , vol.110 , pp. 1245-1250
    • Malik, S.1    Wong, N.D.2    Franklin, S.S.3    Kamath, T.V.4    L'Italien, G.J.5    Pio, J.R.6    Williams, G.R.7
  • 13
    • 33646124715 scopus 로고    scopus 로고
    • Different impact of the metabolic syndrome on left ventricular structure and function in hypertensive men and women
    • Schillaci, G.; Pirro, M.; Pucci, G.; Mannarino, M.R.; Gemelli, F.; Siepi, D.; Vaudo, G. and Mannarino, E. (2006) Different impact of the metabolic syndrome on left ventricular structure and function in hypertensive men and women. Hypertension, 47, 881-886.
    • (2006) Hypertension , vol.47 , pp. 881-886
    • Schillaci, G.1    Pirro, M.2    Pucci, G.3    Mannarino, M.R.4    Gemelli, F.5    Siepi, D.6    Vaudo, G.7    Mannarino, E.8
  • 15
    • 7944236172 scopus 로고    scopus 로고
    • Prevalence of coronary heart disease and carotid arterial thickening in patients with the metabolic syndrome (The ARIC Study)
    • McNeill, A.M.; Rosamond, W.D.; Girman, C.J.; Heiss, G.; Golden, S.H.; Duncan, B.B.; East, H.E. and Ballantyne, C. (2004) Preva- lence of coronary heart disease and carotid arterial thickening in patients with the metabolic syndrome (The ARIC Study). Am. J. Cardiol., 94, 1249-1254.
    • (2004) Am. J. Cardiol , vol.94 , pp. 1249-1254
    • McNeill, A.M.1    Rosamond, W.D.2    Girman, C.J.3    Heiss, G.4    Golden, S.H.5    Duncan, B.B.6    East, H.E.7    Ballantyne, C.8
  • 16
    • 30744460648 scopus 로고    scopus 로고
    • Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study
    • Rutter, M.K.; Meigs, J.B.; Sullivan, L.M.; D'Agostino, R.B.Sr. and Wilson, P.W. (2005) Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study. Diabetes, 54, 3252-3257.
    • (2005) Diabetes , vol.54 , pp. 3252-3257
    • Rutter, M.K.1    Meigs, J.B.2    Sullivan, L.M.3    D'Agostino Sr., R.B.4    Wilson, P.W.5
  • 17
  • 18
    • 33750040555 scopus 로고    scopus 로고
    • Metabolic syndrome and risk for heart failure in middle-aged men
    • Ingelsson, E.; Arnlov, J.; Lind, L. and Sundstrom, J. (2006) Meta- bolic syndrome and risk for heart failure in middle-aged men. Heart, 92, 1409-1413.
    • (2006) Heart , vol.92 , pp. 1409-1413
    • Ingelsson, E.1    Arnlov, J.2    Lind, L.3    Sundstrom, J.4
  • 20
    • 0347716449 scopus 로고    scopus 로고
    • Association of the metabolic syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey
    • Ninomiya, J.K.; L'Italien, G.; Criqui, M.H.; Whyte, J.L.; Gamst, A. and Chen, R.S. (2004) Association of the metabolic syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey. Circulation, 109, 42-46.
    • (2004) Circulation , vol.109 , pp. 42-46
    • Ninomiya, J.K.1    L'Italien, G.2    Criqui, M.H.3    Whyte, J.L.4    Gamst, A.5    Chen, R.S.6
  • 21
    • 33846365989 scopus 로고    scopus 로고
    • Metabolic syndrome and risk of incident cardiovascular events and death: A systematic review and meta-analysis of longitudinal studies
    • Gami, A.S.; Witt, B.J.; Howard, D.E.; Erwin, P.J.; Gami, L.A.; Somers, V.K. and Montori, V.M. (2007) Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J. Am. Coll. Cardiol., 49, 403-414.
    • (2007) J. Am. Coll. Cardiol , vol.49 , pp. 403-414
    • Gami, A.S.1    Witt, B.J.2    Howard, D.E.3    Erwin, P.J.4    Gami, L.A.5    Somers, V.K.6    Montori, V.M.7
  • 22
    • 4444329030 scopus 로고    scopus 로고
    • National Cholesterol Education Program versus World Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study
    • Hunt, K.J.; Resendez, R.G.; Williams, K.; Haffner, S.M. and Stern, M.P. (2004) National Cholesterol Education Program versus World Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study. Circulation, 110, 1251-1257.
    • (2004) Circulation , vol.110 , pp. 1251-1257
    • Hunt, K.J.1    Resendez, R.G.2    Williams, K.3    Haffner, S.M.4    Stern, M.P.5
  • 27
    • 0031435338 scopus 로고    scopus 로고
    • Heritability of cardiovascular risk parameters in subjects with increased susceptibility to non-insulin-dependent diabetes mellitus
    • Bo, S.; Cavallo-Perin, P.; Scaglione, L. and Pagano, G. (1997) Heritability of cardiovascular risk parameters in subjects with in- creased susceptibility to non-insulin-dependent diabetes mellitus. Acta Diabetol., 34, 280-284.
    • (1997) Acta Diabetol , vol.34 , pp. 280-284
    • Bo, S.1    Cavallo-Perin, P.2    Scaglione, L.3    Pagano, G.4
  • 29
    • 0032953097 scopus 로고    scopus 로고
    • Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study
    • Poulsen, P.; Kyvik, K.O.; Vaag, A. and Beck-Nielsen, H. (1999) Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study. Diabetologia, 42, 139-145.
    • (1999) Diabetologia , vol.42 , pp. 139-145
    • Poulsen, P.1    Kyvik, K.O.2    Vaag, A.3    Beck-Nielsen, H.4
  • 31
    • 0030063437 scopus 로고    scopus 로고
    • Genetic and environmental influences on insulin levels and the insulin resistance syndrome: An analysis of women twins
    • Mayer, E.J.; Newman, B.; Austin, M.A.; Zhang, D.; Quesenberry, C.P. Jr.; Edwards, K. and Selby, J.V. (1996) Genetic and environ- mental influences on insulin levels and the insulin resistance syndrome: an analysis of women twins. Am. J. Epidemiol., 143, 323-332.
    • (1996) Am. J. Epidemiol , vol.143 , pp. 323-332
    • Mayer, E.J.1    Newman, B.2    Austin, M.A.3    Zhang, D.4    Quesenberry, C.P.5    Edwards, K.6    Selby, J.V.7
  • 32
    • 0032699817 scopus 로고    scopus 로고
    • General characteristics of the insulin resistance syndrome: Prevalence and heritability. European Group for the study of Insulin Resistance (EGIR)
    • discussion 75-82
    • Beck-Nielsen, H. (1999) General characteristics of the insulin resistance syndrome: prevalence and heritability. European Group for the study of Insulin Resistance (EGIR). Drugs, 58 (Suppl 1), 7-10; discussion 75-82.
    • (1999) Drugs , vol.58 , Issue.SUPPL. 1 , pp. 7-10
    • Beck-Nielsen, H.1
  • 33
    • 26244455316 scopus 로고    scopus 로고
    • Heritabilities of the metabolic syndrome and its components in the Northern Manhattan Family Study
    • Lin, H.F.; Boden-Albala, B.; Juo, S.H.; Park, N.; Rundek, T. and Sacco, R.L. (2005) Heritabilities of the metabolic syndrome and its components in the Northern Manhattan Family Study. Diabetologia, 48, 2006-2012.
    • (2005) Diabetologia , vol.48 , pp. 2006-2012
    • Lin, H.F.1    Boden-Albala, B.2    Juo, S.H.3    Park, N.4    Rundek, T.5    Sacco, R.L.6
  • 34
    • 0035004489 scopus 로고    scopus 로고
    • Genetic versus environmental aetiology of the metabolic syndrome among male and female twins
    • Poulsen, P.; Vaag, A.; Kyvik, K. and Beck-Nielsen, H. (2001) Genetic versus environmental aetiology of the metabolic syndrome among male and female twins. Diabetologia, 44, 537-543.
    • (2001) Diabetologia , vol.44 , pp. 537-543
    • Poulsen, P.1    Vaag, A.2    Kyvik, K.3    Beck-Nielsen, H.4
  • 35
    • 4344628938 scopus 로고    scopus 로고
    • Heritability of ambulatory and office blood pressure phenotypes in Swedish families
    • Fava, C.; Burri, P.; Almgren, P.; Groop, L., Hulthen, U.L. and Melander, O. (2004) Heritability of ambulatory and office blood pressure phenotypes in Swedish families. J. Hypertens., 22, 1717-1721.
    • (2004) J. Hypertens , vol.22 , pp. 1717-1721
    • Fava, C.1    Burri, P.2    Almgren, P.3    Groop, L.4    Hulthen, U.L.5    Melander, O.6
  • 37
    • 51849137780 scopus 로고    scopus 로고
    • Prevalence and heritability of the metabolic syndrome and its individual components in a Dutch isolate: The Erasmus Rucphen Family study
    • Henneman, P.; Aulchenko, Y.S.; Frants, R.R.; van Dijk, K.W.; Oostra, B.A. and van Duijn, C.M. (2008) Prevalence and heritabil- ity of the metabolic syndrome and its individual components in a Dutch isolate: the Erasmus Rucphen Family study. J. Med. Genet., 45, 572-577.
    • (2008) J. Med. Genet , vol.45 , pp. 572-577
    • Henneman, P.1    Aulchenko, Y.S.2    Frants, R.R.3    van Dijk, K.W.4    Oostra, B.A.5    van Duijn, C.M.6
  • 41
    • 0033966429 scopus 로고    scopus 로고
    • Role of hypertension, diabetes, obesity, and race in the development of symptomatic myocardial dysfunction in a predominantly minority population with normal coronary arteries
    • Dwyer, E.M.; Asif, M.; Ippolito, T. and Gillespie, M. (2000) Role of hypertension, diabetes, obesity, and race in the development of symptomatic myocardial dysfunction in a predominantly minority population with normal coronary arteries. Am. Heart J., 139, 297-304.
    • (2000) Am. Heart J , vol.139 , pp. 297-304
    • Dwyer, E.M.1    Asif, M.2    Ippolito, T.3    Gillespie, M.4
  • 42
    • 0029943783 scopus 로고    scopus 로고
    • Impact of ambulatory blood pressure on left ventricular diastolic dysfunction in uncomplicated arterial systemic hypertension
    • Galderisi, M.; Petrocelli, A.; Alfieri, A.; Garofalo, M. and de Divitiis, O. (1996) Impact of ambulatory blood pressure on left ventricular diastolic dysfunction in uncomplicated arterial systemic hypertension. Am. J. Cardiol., 77, 597-601.
    • (1996) Am. J. Cardiol , vol.77 , pp. 597-601
    • Galderisi, M.1    Petrocelli, A.2    Alfieri, A.3    Garofalo, M.4    de Divitiis, O.5
  • 43
    • 0021451873 scopus 로고
    • Left ventricular hypertrophy. Relation of structure to diastolic function in hypertension
    • Shapiro, L.M. and McKenna, W.J. (1984) Left ventricular hyper- trophy. Relation of structure to diastolic function in hypertension. Br. Heart J., 51, 637.
    • (1984) Br. Heart J , vol.51 , pp. 637
    • Shapiro, L.M.1    McKenna, W.J.2
  • 44
    • 0029127729 scopus 로고
    • Prevalence and determinants of cardiac and vascular hypertrophy in hypertension
    • Roman, M.J.; Pickering, T.G.; Pini, R.; Schwartz, J.E. and Devereux, R.B. (1995) Prevalence and determinants of cardiac and vascular hypertrophy in hypertension. Hypertension, 26, 369-373.
    • (1995) Hypertension , vol.26 , pp. 369-373
    • Roman, M.J.1    Pickering, T.G.2    Pini, R.3    Schwartz, J.E.4    Devereux, R.B.5
  • 45
    • 34249739139 scopus 로고    scopus 로고
    • Risk factors for the progression of coronary artery calcification in asymptomatic subjects: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)
    • Kronmal, R.A.; McClelland, R.L.; Detrano, R.; Shea, S.; Lima, J.A.; Cushman, M.; Bild, D.E. and Burke, G.L. (2007) Risk factors for the progression of coronary artery calcification in asymptomatic subjects: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation, 115, 2722-2730.
    • (2007) Circulation , vol.115 , pp. 2722-2730
    • Kronmal, R.A.1    McClelland, R.L.2    Detrano, R.3    Shea, S.4    Lima, J.A.5    Cushman, M.6    Bild, D.E.7    Burke, G.L.8
  • 48
    • 31944451578 scopus 로고    scopus 로고
    • Risk factors for arterial hypertension in adults with initial optimal blood pressure: The Strong Heart Study
    • and Strong Heart Study, I
    • de Simone, G.; Devereux, R.B.; Chinali, M.; Roman, M.J.; Best, L.G.; Welty, T.K.; Lee, E.T.; Howard, B.V. and Strong Heart Study, I. (2006) Risk factors for arterial hypertension in adults with initial optimal blood pressure: the Strong Heart Study. Hypertension, 47, 162-167.
    • (2006) Hypertension , vol.47 , pp. 162-167
    • de Simone, G.1    Devereux, R.B.2    Chinali, M.3    Roman, M.J.4    Best, L.G.5    Welty, T.K.6    Lee, E.T.7    Howard, B.V.8
  • 52
    • 0036845379 scopus 로고    scopus 로고
    • Abdomi- nal obesity, muscle composition, and insulin resistance in premenopausal women
    • Ross, R.; Freeman, J.; Hudson, R. and Janssen, I. (2002) Abdomi- nal obesity, muscle composition, and insulin resistance in premenopausal women. J. Clin. Endocrinol. Metab., 87, 5044-5051.
    • (2002) J. Clin. Endocrinol. Metab , vol.87 , pp. 5044-5051
    • Ross, R.1    Freeman, J.2    Hudson, R.3    Janssen, I.4
  • 53
    • 20744439123 scopus 로고    scopus 로고
    • Relation of high-sensitivity C-reactive protein, interleukin-6, tumor necrosis factor-alpha, and fibrinogen to abdominal adipose tissue, blood pressure, and cholesterol and triglyceride levels in healthy postmenopausal women
    • Piche, M.E.; Lemieux, S.; Weisnagel, S.J.; Corneau, L.; Nadeau, A. and Bergeron, J. (2005). Relation of high-sensitivity C-reactive protein, interleukin-6, tumor necrosis factor-alpha, and fibrinogen to abdominal adipose tissue, blood pressure, and cholesterol and triglyceride levels in healthy postmenopausal women. Am. J. Cardiol., 96, 92-97.
    • (2005) Am. J. Cardiol , vol.96 , pp. 92-97
    • Piche, M.E.1    Lemieux, S.2    Weisnagel, S.J.3    Corneau, L.4    Nadeau, A.5    Bergeron, J.6
  • 55
    • 0025084193 scopus 로고
    • Assessment of cardiac function in patients who were morbidly obese
    • Alaud-din, A.; Meterissian, S.; Lisbona, R.; MacLean, L.D. and Forse, R.A. (1990) Assessment of cardiac function in patients who were morbidly obese. Surgery, 108, 809-818.
    • (1990) Surgery , vol.108 , pp. 809-818
    • Alaud-Din, A.1    Meterissian, S.2    Lisbona, R.3    Maclean, L.D.4    Forse, R.A.5
  • 56
    • 0032196819 scopus 로고    scopus 로고
    • Effects of obesity and weight loss on cardiac function and valvular performance
    • Karason, K.; Wallentin, I.; Larsson, B. and Sjostrom, L. (1998) Effects of obesity and weight loss on cardiac function and valvular performance. Obes. Res., 6, 422-429.
    • (1998) Obes. Res , vol.6 , pp. 422-429
    • Karason, K.1    Wallentin, I.2    Larsson, B.3    Sjostrom, L.4
  • 57
    • 0025773972 scopus 로고
    • The impact of obesity on left ventricular mass and geometry. The Framingham Heart Study
    • Lauer, M.S.; Anderson, K.M.; Kannel, W.B. and Levy, D. (1991) The impact of obesity on left ventricular mass and geometry. The Framingham Heart Study. JAMA, 266, 231-236.
    • (1991) JAMA , vol.266 , pp. 231-236
    • Lauer, M.S.1    Anderson, K.M.2    Kannel, W.B.3    Levy, D.4
  • 58
    • 0028827534 scopus 로고
    • Rela- tion of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss
    • Alpert, M.A.; Lambert, C.R.; Panayiotou, H.; Terry, B.E.; Cohen, M.V.; Massey, C.V.; Hashimi, M.W. and Mukerji, V. (1995) Rela- tion of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss. Am. J. Cardiol., 76, 1194-1197.
    • (1995) Am. J. Cardiol , vol.76 , pp. 1194-1197
    • Alpert, M.A.1    Lambert, C.R.2    Panayiotou, H.3    Terry, B.E.4    Cohen, M.V.5    Massey, C.V.6    Hashimi, M.W.7    Mukerji, V.8
  • 62
    • 35848935201 scopus 로고    scopus 로고
    • Cause-specific excess deaths associated with underweight, overweight, and obesity
    • Flegal, K.M.; Graubard, B.I.; Williamson, D.F. and Gail, M.H. (2007) Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA, 298, 2028-2037.
    • (2007) JAMA , vol.298 , pp. 2028-2037
    • Flegal, K.M.1    Graubard, B.I.2    Williamson, D.F.3    Gail, M.H.4
  • 64
    • 0028355370 scopus 로고
    • Relation of obesity and gender to left ventricular hypertrophy in normotensive and hypertensive adults
    • de Simone, G.; Devereux, R.B., Roman, M.J.; Alderman, M.H. and Laragh, J.H. (1994) Relation of obesity and gender to left ventricular hypertrophy in normotensive and hypertensive adults. Hypertension, 23, 600-606.
    • (1994) Hypertension , vol.23 , pp. 600-606
    • de Simone, G.1    Devereux, R.B.2    Roman, M.J.3    Alderman, M.H.4    Laragh, J.H.5
  • 65
    • 41149105807 scopus 로고    scopus 로고
    • Left ventricular mass predicts heart failure not related to previous myocardial infarction: The Cardiovascular Health Study
    • de Simone, G.; Gottdiener, J.S.; Chinali, M. and Maurer, M.S. (2008) Left ventricular mass predicts heart failure not related to previous myocardial infarction: the Cardiovascular Health Study. Eur. Heart J., 29, 741-747.
    • (2008) Eur. Heart J , vol.29 , pp. 741-747
    • de Simone, G.1    Gottdiener, J.S.2    Chinali, M.3    Maurer, M.S.4
  • 68
    • 31544480404 scopus 로고    scopus 로고
    • Cardiovascular mortality in overweight subjects: The key role of associated risk factors
    • Thomas, F.; Bean, K.; Pannier, B.; Oppert, J.M.; Guize, L. and Benetos, A. (2005) Cardiovascular mortality in overweight subjects: the key role of associated risk factors. Hypertension, 46, 654-659.
    • (2005) Hypertension , vol.46 , pp. 654-659
    • Thomas, F.1    Bean, K.2    Pannier, B.3    Oppert, J.M.4    Guize, L.5    Benetos, A.6
  • 69
    • 35348846641 scopus 로고    scopus 로고
    • Disparate effects of left ventricular geometry and obesity on mortality in patients with preserved left ventricular ejection fraction
    • Lavie, C.J.; Milani, R.V.; Ventura, H.O.; Cardenas, G.A.; Mehra, M.R. and Messerli, F.H. (2007) Disparate effects of left ventricular geometry and obesity on mortality in patients with preserved left ventricular ejection fraction. Am. J. Cardiol., 100, 1460-1464.
    • (2007) Am. J. Cardiol , vol.100 , pp. 1460-1464
    • Lavie, C.J.1    Milani, R.V.2    Ventura, H.O.3    Cardenas, G.A.4    Mehra, M.R.5    Messerli, F.H.6
  • 72
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • Bansal, S.; Buring, J.E.; Rifai, N.; Mora, S.; Sacks, F.M. and Ridker, P.M. (2007) Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA, 298, 309-316.
    • (2007) JAMA , vol.298 , pp. 309-316
    • Bansal, S.1    Buring, J.E.2    Rifai, N.3    Mora, S.4    Sacks, F.M.5    Ridker, P.M.6
  • 74
    • 0036336187 scopus 로고    scopus 로고
    • Prevalence of 'hypertriglyceridemic waist' in men who participated in the Quebec Health Survey: Association with atherogenic and diabetogenic metabolic risk factors
    • Lemieux, I.; Almeras, N.; Mauriege, P.; Blanchet, C.; Dewailly, E.; Bergeron, J. and Despres, J.P. (2002) Prevalence of 'hypertriglyceridemic waist' in men who participated in the Quebec Health Survey: association with atherogenic and diabetogenic metabolic risk factors. Can. J. Cardiol., 18, 725-732.
    • (2002) Can. J. Cardiol , vol.18 , pp. 725-732
    • Lemieux, I.1    Almeras, N.2    Mauriege, P.3    Blanchet, C.4    Dewailly, E.5    Bergeron, J.6    Despres, J.P.7
  • 75
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study
    • Gordon, T.; Castelli, W.P.; Hjortland, M.C.; Kannel, W.B. and Dawber, T.R. (1977) High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am. J. Med., 62, 707-714.
    • (1977) Am. J. Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3    Kannel, W.B.4    Dawber, T.R.5
  • 76
    • 0036637538 scopus 로고    scopus 로고
    • Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: The San Antonio Heart Study
    • Hanley, A.J.; Williams, K.; Stern, M.P. and Haffner, S.M. (2002) Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: the San Antonio Heart Study. Diabetes Care, 25, 1177-1184.
    • (2002) Diabetes Care , vol.25 , pp. 1177-1184
    • Hanley, A.J.1    Williams, K.2    Stern, M.P.3    Haffner, S.M.4
  • 77
    • 58149348524 scopus 로고    scopus 로고
    • All-cause mortality risk predictors in a preventive cardiology clinic cohort-examining diabetes and individual metabolic syndrome criteria: A PRECIS database study
    • Doshi, K.B.; Kashyap, S.R.; Brennan, D.M.; Hoar, B.M.; Cho, L. and Hoogwerf, B.J. (2009) All-cause mortality risk predictors in a preventive cardiology clinic cohort-examining diabetes and individual metabolic syndrome criteria: a PRECIS database study. Diabetes Obes. Metab., 11, 102-108.
    • (2009) Diabetes Obes. Metab , vol.11 , pp. 102-108
    • Doshi, K.B.1    Kashyap, S.R.2    Brennan, D.M.3    Hoar, B.M.4    Cho, L.5    Hoogwerf, B.J.6
  • 78
    • 0034019968 scopus 로고    scopus 로고
    • Diabetes mellitus, coronary heart disease incidence, and death from all causes in African American and European American women: The NHANES I epidemiologic follow-up study
    • Gillum, R.F.; Mussolino, M.E. and Madans, J.H. (2000) Diabetes mellitus, coronary heart disease incidence, and death from all causes in African American and European American women: The NHANES I epidemiologic follow-up study. J. Clin. Epidemiol., 53, 511-518.
    • (2000) J. Clin. Epidemiol , vol.53 , pp. 511-518
    • Gillum, R.F.1    Mussolino, M.E.2    Madans, J.H.3
  • 79
    • 65349085059 scopus 로고    scopus 로고
    • Trends in allcause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005
    • Preis, S.R.; Hwang, S.J.; Coady, S.; Pencina, M.J.; D'Agostino, R.B.Sr.; Savage, P.J.; Levy, D. and Fox, C.S. (2009) Trends in allcause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005. Circulation, 119, 1728-1735.
    • (2009) Circulation , vol.119 , pp. 1728-1735
    • Preis, S.R.1    Hwang, S.J.2    Coady, S.3    Pencina, M.J.4    D'Agostino Sr., R.B.5    Savage, P.J.6    Levy, D.7    Fox, C.S.8
  • 80
    • 0030025673 scopus 로고    scopus 로고
    • Hypertension and associated metabolic abnormalities - the role of insulin resistance and the sympathoadrenal system
    • Reaven, G.M.; Litheli, H. and Landsberg, L. (1996) Hypertension and associated metabolic abnormalities - the role of insulin resistance and the sympathoadrenal system. N. Engl. J. Med., 334, 374.
    • (1996) N. Engl. J. Med , vol.334 , pp. 374
    • Reaven, G.M.1    Litheli, H.2    Landsberg, L.3
  • 81
    • 0035089472 scopus 로고    scopus 로고
    • The renin-angiotensin system and natriuretic peptides in obesity-associated hypertension. J. Mol
    • Engeli, S. and Sharma, A.M. (2001) The renin-angiotensin system and natriuretic peptides in obesity-associated hypertension. J. Mol. Med., 79, 21-29.
    • (2001) Med , vol.79 , pp. 21-29
    • Engeli, S.1    Sharma, A.M.2
  • 83
    • 0037015288 scopus 로고    scopus 로고
    • Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: Effects of short- and long-term simvastatin treatment
    • Ceriello, A.; Taboga, C.; Tonutti, L.; Quagliaro, L.; Piconi, L.; Bais, B.; Da Ros, R. and Motz, E. (2002) Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment. Circulation, 106, 1211-1218.
    • (2002) Circulation , vol.106 , pp. 1211-1218
    • Ceriello, A.1    Taboga, C.2    Tonutti, L.3    Quagliaro, L.4    Piconi, L.5    Bais, B.6    da Ros, R.7    Motz, E.8
  • 84
    • 0034003574 scopus 로고    scopus 로고
    • Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulinresistant prediabetic stage of a type II diabetic rat model
    • Mizushige, K.; Yao, L.; Noma, T.; Kiyomoto, H.; Yu, Y.; Hosomi, N.; Ohmori, K. and Matsuo, H. (2000) Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulinresistant prediabetic stage of a type II diabetic rat model. Circulation, 101, 899-907.
    • (2000) Circulation , vol.101 , pp. 899-907
    • Mizushige, K.1    Yao, L.2    Noma, T.3    Kiyomoto, H.4    Yu, Y.5    Hosomi, N.6    Ohmori, K.7    Matsuo, H.8
  • 89
    • 0030002580 scopus 로고    scopus 로고
    • The progression from hypertension to congestive heart failure
    • Levy, D.; Larson, M.G.; Vasan, R.S.; Kannel, W.B. and Ho, K.K. (1996) The progression from hypertension to congestive heart failure. JAMA, 275, 1557-1562.
    • (1996) JAMA , vol.275 , pp. 1557-1562
    • Levy, D.1    Larson, M.G.2    Vasan, R.S.3    Kannel, W.B.4    Ho, K.K.5
  • 90
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
    • Stratton, I.M.; Adler, A.I.; Neil, H.A.; Matthews, D.R.; Manley, S.E.; Cull, C.A.; Hadden, D.; Turner, R.C. and Holman, R.R. (2000) Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ, 321, 405-412.
    • (2000) BMJ , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.3    Matthews, D.R.4    Manley, S.E.5    Cull, C.A.6    Hadden, D.7    Turner, R.C.8    Holman, R.R.9
  • 93
    • 0038488294 scopus 로고    scopus 로고
    • Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus
    • Diamant, M.; Lamb, H.J.; Groeneveld, Y.; Endert, E.L.; Smit, J.W.; Bax, J.J.; Romijn, J.A.; de Roos, A. and Radder, J.K. (2003) Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus. J. Am. Coll. Cardiol., 42, 328-335.
    • (2003) J. Am. Coll. Cardiol , vol.42 , pp. 328-335
    • Diamant, M.1    Lamb, H.J.2    Groeneveld, Y.3    Endert, E.L.4    Smit, J.W.5    Bax, J.J.6    Romijn, J.A.7    de Roos, A.8    Radder, J.K.9
  • 95
    • 0042532204 scopus 로고    scopus 로고
    • Patients with early diabetic heart disease demonstrate a normal myocardial response to dobutamine
    • Fang, Z.Y.; Najos-Valencia, O.; Leano, R. and Marwick, T.H. (2003) Patients with early diabetic heart disease demonstrate a normal myocardial response to dobutamine. J. Am. Coll. Cardiol., 42, 446-453.
    • (2003) J. Am. Coll. Cardiol , vol.42 , pp. 446-453
    • Fang, Z.Y.1    Najos-Valencia, O.2    Leano, R.3    Marwick, T.H.4
  • 96
    • 33645280925 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: The search for a unifying hypothesis
    • Poornima, I.G.; Parikh, P. and Shannon, R.P. (2006) Diabetic cardiomyopathy: the search for a unifying hypothesis. Circ. Res., 98, 596-605.
    • (2006) Circ. Res , vol.98 , pp. 596-605
    • Poornima, I.G.1    Parikh, P.2    Shannon, R.P.3
  • 98
    • 14744295045 scopus 로고    scopus 로고
    • Tissue Doppler imaging for the detection and quantitation of myocardial dysfunction in patients with type 2 diabetes mellitus
    • Von Bibra, H.; Thrainsdottir, I.S.; Hansen, A.; Dounis, V.; Malmberg, K. and Ryden, L. (2005) Tissue Doppler imaging for the detection and quantitation of myocardial dysfunction in patients with type 2 diabetes mellitus. Diab. Vasc. Dis. Res., 2, 24-30.
    • (2005) Diab. Vasc. Dis. Res , vol.2 , pp. 24-30
    • von Bibra, H.1    Thrainsdottir, I.S.2    Hansen, A.3    Dounis, V.4    Malmberg, K.5    Ryden, L.6
  • 99
    • 33748515649 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus
    • Westermann, D.; Rutschow, S.; Van Linthout, S.; Linderer, A.; Bucker-Gartner, C.; Sobirey, M.; Riad, A.; Pauschinger, M.; Schultheiss, H.P. and Tschope, C. (2006) Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus. Diabetologia, 49, 2507-2513.
    • (2006) Diabetologia , vol.49 , pp. 2507-2513
    • Westermann, D.1    Rutschow, S.2    van Linthout, S.3    Linderer, A.4    Bucker-Gartner, C.5    Sobirey, M.6    Riad, A.7    Pauschinger, M.8    Schultheiss, H.P.9    Tschope, C.10
  • 100
    • 4143140134 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Evidence, mechanisms, and therapeutic implications
    • Fang, Z.Y.; Prins, J.B. and Marwick, T.H. (2004) Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications. Endocr. Rev., 25, 543-567.
    • (2004) Endocr. Rev , vol.25 , pp. 543-567
    • Fang, Z.Y.1    Prins, J.B.2    Marwick, T.H.3
  • 101
    • 0035897696 scopus 로고    scopus 로고
    • Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)
    • Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). (2001) JAMA, 285, 2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 102
    • 43449132399 scopus 로고    scopus 로고
    • Cardiometabolic risk: A Framingham perspective
    • Wilson, P.W. and Meigs, J.B. (2008) Cardiometabolic risk: a Framingham perspective. Int. J. Obes. (Lond), 32 (Suppl 2), S17-S20.
    • (2008) Int. J. Obes. (Lond) , vol.32 , Issue.SUPPL. 2
    • Wilson, P.W.1    Meigs, J.B.2
  • 103
    • 3042755369 scopus 로고    scopus 로고
    • Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: Subgroup analyses of the Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival, S
    • Pyorala, K.; Ballantyne, C.M.; Gumbiner, B.; Lee, M.W.; Shah, A.; Davies, M.J.; Mitchel, Y.B.; Pedersen, T.R.; Kjekshus, J. and Scandinavian Simvastatin Survival, S. (2004) Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: subgroup analyses of the Scandinavian Simvastatin Survival Study (4S). Diabetes Care, 27, 1735-1740.
    • (2004) Diabetes Care , vol.27 , pp. 1735-1740
    • Pyorala, K.1    Ballantyne, C.M.2    Gumbiner, B.3    Lee, M.W.4    Shah, A.5    Davies, M.J.6    Mitchel, Y.B.7    Pedersen, T.R.8    Kjekshus, J.9
  • 104
    • 0032513756 scopus 로고    scopus 로고
    • Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: Meta-analyses of prospective studies
    • Danesh, J.; Collins, R.; Appleby, P. and Peto, R. (1998) Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. JAMA, 279, 1477-1482.
    • (1998) JAMA , vol.279 , pp. 1477-1482
    • Danesh, J.1    Collins, R.2    Appleby, P.3    Peto, R.4
  • 105
    • 0037024226 scopus 로고    scopus 로고
    • Effects of cholesterol and inflammationsensitive plasma proteins on incidence of myocardial infarction and stroke in men
    • Engstrom, G.; Lind, P.; Hedblad, B.; Stavenow, L.; Janzon, L. and Lindgarde, F. (2002) Effects of cholesterol and inflammationsensitive plasma proteins on incidence of myocardial infarction and stroke in men. Circulation, 105, 2632-2637.
    • (2002) Circulation , vol.105 , pp. 2632-2637
    • Engstrom, G.1    Lind, P.2    Hedblad, B.3    Stavenow, L.4    Janzon, L.5    Lindgarde, F.6
  • 108
  • 110
    • 40949120497 scopus 로고    scopus 로고
    • From a glucocentric to a lipocentric approach towards metabolic syndrome
    • Mittra, S.; Bansal, V.S. and Bhatnagar, P.K. (2008) From a glucocentric to a lipocentric approach towards metabolic syndrome. Drug Discov. Today, 13, 211-218.
    • (2008) Drug Discov. Today , vol.13 , pp. 211-218
    • Mittra, S.1    Bansal, V.S.2    Bhatnagar, P.K.3
  • 111
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Chinetti, G.; Fruchart, J.C. and Staels, B. (2000) Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm. Res., 49, 497-505.
    • (2000) Inflamm. Res , vol.49 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.C.2    Staels, B.3
  • 112
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha
    • Suganami, T.; Nishida, J. and Ogawa, Y. (2005) A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler. Thromb. Vasc. Biol., 25, 2062-2068.
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 113
    • 12844262139 scopus 로고    scopus 로고
    • The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study
    • McNeill, A.M.; Rosamond, W.D.; Girman, C.J.; Golden, S.H.; Schmidt, M.I.; East, H.E.; Ballantyne, C.M. and Heiss, G. (2005) The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care, 28, 385-390.
    • (2005) Diabetes Care , vol.28 , pp. 385-390
    • McNeill, A.M.1    Rosamond, W.D.2    Girman, C.J.3    Golden, S.H.4    Schmidt, M.I.5    East, H.E.6    Ballantyne, C.M.7    Heiss, G.8
  • 114
    • 12444296524 scopus 로고    scopus 로고
    • Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus
    • Heilbronn, L.; Smith, S.R. and Ravussin, E. (2004) Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus. Int. J. Obes. Relat. Metab. Disord., 28 (Suppl 4), S12-S21.
    • (2004) Int. J. Obes. Relat. Metab. Disord , vol.28 , Issue.SUPPL. 4
    • Heilbronn, L.1    Smith, S.R.2    Ravussin, E.3
  • 116
    • 29244465509 scopus 로고    scopus 로고
    • Human fat cell lipolysis: Biochemistry, regulation and clinical role
    • Arner, P. (2005) Human fat cell lipolysis: biochemistry, regulation and clinical role. Best Pract. Res. Clin. Endocrinol. Metab., 19, 471-482.
    • (2005) Best Pract. Res. Clin. Endocrinol. Metab , vol.19 , pp. 471-482
    • Arner, P.1
  • 118
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle, P.J.; Garland, P.B.; Hales, C.N. and Newsholme, E.A. (1963) The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet, 1, 785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 119
    • 0035125917 scopus 로고    scopus 로고
    • Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover
    • Unger, R.H. and Zhou, Y.T. (2001) Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover. Diabetes, 40, S118.
    • (2001) Diabetes , vol.40
    • Unger, R.H.1    Zhou, Y.T.2
  • 120
    • 33646806826 scopus 로고    scopus 로고
    • Lipotoxicity, overnutrition and energy metabolism in aging
    • Slawik, M. and Vidal-Puig, A.J. (2006) Lipotoxicity, overnutrition and energy metabolism in aging. Ageing Res. Rev., 5, 144-164.
    • (2006) Ageing Res. Rev , vol.5 , pp. 144-164
    • Slawik, M.1    Vidal-Puig, A.J.2
  • 122
    • 0037219524 scopus 로고    scopus 로고
    • Myocardial fatty acid metabolism: Independent predictor of left ventricular mass in hypertensive heart disease
    • de las Fuentes, L.; Herrero, P.; Peterson, L.R.; Kelly, D.P.; Gropler, R.J. and Davila-Roman, V.G.; eds
    • de las Fuentes, L.; Herrero, P.; Peterson, L.R.; Kelly, D.P.; Gropler, R.J. and Davila-Roman, V.G.; eds. Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease. Hypertension. Vol. 41. 2003. 83-87.
    • Hypertension , vol.41 , pp. 83-87
  • 125
    • 0037417725 scopus 로고    scopus 로고
    • A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
    • Finck, B.N.; Han, X.; Courtois, M.; Aimond, F.; Nerbonne, J.M.; Kovacs, A.; Gross, R.W. and Kelly, D.P. (2003) A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proc. Natl. Acad. Sci. USA, 100, 1226-1231.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1226-1231
    • Finck, B.N.1    Han, X.2    Courtois, M.3    Aimond, F.4    Nerbonne, J.M.5    Kovacs, A.6    Gross, R.W.7    Kelly, D.P.8
  • 126
    • 0033933236 scopus 로고    scopus 로고
    • Deactivation of peroxisome proliferatoractivated receptor-alpha during cardiac hypertrophic growth
    • Barger, P.M.; Brandt, J.M.; Leone, T.C.; Weinheimer, C.J. and Kelly, D.P. (2000) Deactivation of peroxisome proliferatoractivated receptor-alpha during cardiac hypertrophic growth. J. Clin. Invest., 105, 1723-1730.
    • (2000) J. Clin. Invest , vol.105 , pp. 1723-1730
    • Barger, P.M.1    Brandt, J.M.2    Leone, T.C.3    Weinheimer, C.J.4    Kelly, D.P.5
  • 128
    • 29244474362 scopus 로고    scopus 로고
    • Plasma triglyceride level is an independent predictor of altered left ventricular relaxation
    • de las Fuentes, L.; Waggoner, A.D.; Brown, A.L. and Davila-Roman, V.G. (2005) Plasma triglyceride level is an independent predictor of altered left ventricular relaxation. J. Am. Soc. Echocardiogr., 18, 1285-1291.
    • (2005) J. Am. Soc. Echocardiogr , vol.18 , pp. 1285-1291
    • de las Fuentes, L.1    Waggoner, A.D.2    Brown, A.L.3    Davila-Roman, V.G.4
  • 129
    • 0032854610 scopus 로고    scopus 로고
    • Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm
    • Abumrad, N.; Coburn, C. and Ibrahimi, A. (1999) Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. Biochim. Biophys. Acta, 1441, 4-13.
    • (1999) Biochim. Biophys. Acta , vol.1441 , pp. 4-13
    • Abumrad, N.1    Coburn, C.2    Ibrahimi, A.3
  • 130
    • 0031759759 scopus 로고    scopus 로고
    • Muscle contraction increases palmitate esterification and oxidation and triacylglycerol oxidation
    • Dyck, D.J. and Bonen, A. (1998) Muscle contraction increases palmitate esterification and oxidation and triacylglycerol oxidation. Am. J. Physiol. Endocrinol. Metab., 275, E888-E896.
    • (1998) Am. J. Physiol. Endocrinol. Metab , vol.275
    • Dyck, D.J.1    Bonen, A.2
  • 132
    • 0029087541 scopus 로고
    • Heart CD36 expression is increased in murine models of diabetes and in mice fed a high fat diet
    • Greenwalt, D.E.; Scheck, S.H. and Rhinehart-Jones, T. (1995) Heart CD36 expression is increased in murine models of diabetes and in mice fed a high fat diet. J. Clin. Invest., 96, 1382-1388.
    • (1995) J. Clin. Invest , vol.96 , pp. 1382-1388
    • Greenwalt, D.E.1    Scheck, S.H.2    Rhinehart-Jones, T.3
  • 134
    • 0035968175 scopus 로고    scopus 로고
    • Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy
    • Hajri, T.; Ibrahimi, A.; Coburn, C.T.; Knapp, F.F.Jr.; Kurtz, T.; Pravenec, M. and Abumrad, N.A. (2001) Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy. J. Biol. Chem., 276, 23661-23666.
    • (2001) J. Biol. Chem , vol.276 , pp. 23661-23666
    • Hajri, T.1    Ibrahimi, A.2    Coburn, C.T.3    Knapp Jr., F.F.4    Kurtz, T.5    Pravenec, M.6    Abumrad, N.A.7
  • 138
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz, P.; Nagy, L.; Alvarez, J.G.; Thomazy, V.A. and Evans, R.M. (1998) PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell, 93, 241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 139
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy, L.; Tontonoz, P.; Alvarez, J.G.; Chen, H. and Evans, R.M. (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell, 93, 229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 140
    • 33644660537 scopus 로고    scopus 로고
    • PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease
    • Finck, B.N. and Kelly, D.P. (2006) PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J. Clin. Invest., 116, 615-622.
    • (2006) J. Clin. Invest , vol.116 , pp. 615-622
    • Finck, B.N.1    Kelly, D.P.2
  • 141
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin, J.; Handschin, C. and Spiegelman, B.M. (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab., 1, 361-370.
    • (2005) Cell Metab , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 147
    • 0037392395 scopus 로고    scopus 로고
    • Pegylated human recombinant leptin (PEG-OB) causes additional weight loss in severely energy-restricted, overweight men
    • Hukshorn, C.J.; Westerterp-Plantenga, M.S. and Saris, W.H. (2003) Pegylated human recombinant leptin (PEG-OB) causes additional weight loss in severely energy-restricted, overweight men. Am. J. Clin. Nutr., 77, 771-776.
    • (2003) Am. J. Clin. Nutr , vol.77 , pp. 771-776
    • Hukshorn, C.J.1    Westerterp-Plantenga, M.S.2    Saris, W.H.3
  • 148
    • 40949127502 scopus 로고    scopus 로고
    • Hypoadiponectinemia as a marker of adipocyte dysfunction--part II: The functional significance of low adiponectin secretion
    • Stern, N.; Osher, E. and Greenman, Y. (2007) Hypoadiponectinemia as a marker of adipocyte dysfunction--part II: the functional significance of low adiponectin secretion. J. Cardiometab. Syndr., 2, 288-294.
    • (2007) J. Cardiometab. Syndr , vol.2 , pp. 288-294
    • Stern, N.1    Osher, E.2    Greenman, Y.3
  • 149
    • 38449089805 scopus 로고    scopus 로고
    • Hypoadiponectinemia as a marker of adipocyte dysfunction -- Part I: The biology of adiponectin
    • Stern, N.; Osher, E. and Greenman, Y. (2007) Hypoadiponectinemia as a marker of adipocyte dysfunction -- Part I: the biology of adiponectin. J. Cardiometab. Syndr., 2, 174-182.
    • (2007) J. Cardiometab. Syndr , vol.2 , pp. 174-182
    • Stern, N.1    Osher, E.2    Greenman, Y.3
  • 150
    • 0030458404 scopus 로고    scopus 로고
    • Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha
    • Zhang, B.; Berger, J.; Hu, E.; Szalkowski, D.; White-Carrington, S.; Spiegelman, B.M. and Moller, D.E. (1996) Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha. Mol. Endocrinol., 10, 1457-1466.
    • (1996) Mol. Endocrinol , vol.10 , pp. 1457-1466
    • Zhang, B.1    Berger, J.2    Hu, E.3    Szalkowski, D.4    White-Carrington, S.5    Spiegelman, B.M.6    Moller, D.E.7
  • 151
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • Kern, P.A.; Saghizadeh, M.; Ong, J.M.; Bosch, R.J.; Deem, R. and Simsolo, R.B. (1995) The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J. Clin. Invest., 95, 2111-2119.
    • (1995) J. Clin. Invest , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizadeh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 152
    • 0035908632 scopus 로고    scopus 로고
    • C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
    • Pradhan, A.D.; Manson, J.E.; Rifai, N.; Buring, J.E. and Ridker, P.M. (2001) C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA, 286, 327-334.
    • (2001) JAMA , vol.286 , pp. 327-334
    • Pradhan, A.D.1    Manson, J.E.2    Rifai, N.3    Buring, J.E.4    Ridker, P.M.5
  • 153
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai, D.; Yuan, M.; Frantz, D.F.; Melendez, P.A.; Hansen, L.; Lee, J. and Shoelson, S.E. (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat. Med., 11, 183-190.
    • (2005) Nat. Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5    Lee, J.6    Shoelson, S.E.7
  • 154
    • 0035979775 scopus 로고    scopus 로고
    • Reversal of obesity- and dietinduced insulin resistance with salicylates or targeted disruption of Ikkbeta
    • Yuan, M.; Konstantopoulos, N.; Lee, J.; Hansen, L.; Li, Z.W.; Karin, M. and Shoelson, S.E. (2001) Reversal of obesity- and dietinduced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science, 293, 1673-1677.
    • (2001) Science , vol.293 , pp. 1673-1677
    • Yuan, M.1    Konstantopoulos, N.2    Lee, J.3    Hansen, L.4    Li, Z.W.5    Karin, M.6    Shoelson, S.E.7
  • 155
    • 28544453229 scopus 로고    scopus 로고
    • Role of nuclear factor-kappaB in the immune system and bone
    • Jimi, E. and Ghosh, S. (2005) Role of nuclear factor-kappaB in the immune system and bone. Immunol. Rev., 208, 80-87.
    • (2005) Immunol. Rev , vol.208 , pp. 80-87
    • Jimi, E.1    Ghosh, S.2
  • 156
    • 28944444198 scopus 로고    scopus 로고
    • Nuclear factor-kappaB
    • Zingarelli, B. (2005) Nuclear factor-kappaB. Crit. Care Med., 33, S414-S416.
    • (2005) Crit. Care Med , vol.33
    • Zingarelli, B.1
  • 158
    • 0142085794 scopus 로고    scopus 로고
    • NF-kappaB as an integrator of diverse signaling pathways: The heart of myocardial signaling?
    • Jones, W.K.; Brown, M.; Ren, X.; He, S. and McGuinness, M. (2003) NF-kappaB as an integrator of diverse signaling pathways: the heart of myocardial signaling? Cardiovasc. Toxicol., 3, 229-254.
    • (2003) Cardiovasc. Toxicol , vol.3 , pp. 229-254
    • Jones, W.K.1    Brown, M.2    Ren, X.3    He, S.4    McGuinness, M.5
  • 159
    • 13444256258 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase protects the heart against cardiac remodeling in mice with heart failure resulting from myocardial infarction
    • Liu, Y.H.; Wang, D.; Rhaleb, N.E.; Yang, X.P.; Xu, J.; Sankey, S.S.; Rudolph, A.E. and Carretero, O.A. (2005) Inhibition of p38 mitogen-activated protein kinase protects the heart against cardiac remodeling in mice with heart failure resulting from myocardial infarction. J. Card. Fail., 11, 74-81.
    • (2005) J. Card. Fail , vol.11 , pp. 74-81
    • Liu, Y.H.1    Wang, D.2    Rhaleb, N.E.3    Yang, X.P.4    Xu, J.5    Sankey, S.S.6    Rudolph, A.E.7    Carretero, O.A.8
  • 160
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogenactivated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis, J.M. and Avruch, J. (2001) Mammalian mitogenactivated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev., 81, 807-869.
    • (2001) Physiol. Rev , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 161
    • 0036843158 scopus 로고    scopus 로고
    • Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death
    • Bueno, O.F. and Molkentin, J.D. (2002) Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death. Circ. Res., 91, 776-781.
    • (2002) Circ. Res , vol.91 , pp. 776-781
    • Bueno, O.F.1    Molkentin, J.D.2
  • 162
    • 0037040161 scopus 로고    scopus 로고
    • p38 Mitogenactivated protein kinase mediates a negative inotropic effect in cardiac myocytes
    • Liao, P.; Wang, S.Q.; Wang, S.; Zheng, M.; Zheng, M.; Zhang, S.J.; Cheng, H.; Wang, Y. and Xiao, R.P. (2002) p38 Mitogenactivated protein kinase mediates a negative inotropic effect in cardiac myocytes. Circ. Res., 90, 190-196.
    • (2002) Circ. Res , vol.90 , pp. 190-196
    • Liao, P.1    Wang, S.Q.2    Wang, S.3    Zheng, M.4    Zheng, M.5    Zhang, S.J.6    Cheng, H.7    Wang, Y.8    Xiao, R.P.9
  • 163
    • 0029791412 scopus 로고    scopus 로고
    • PPARalpha and PPARgamma activators direct a distinct tissuespecific transcriptional response via a PPRE in the lipoprotein lipase gene
    • Schoonjans, K.; Peinado-Onsurbe, J.; Lefebvre, A.M.; Heyman, R.A.; Briggs, M.; Deeb, S.; Staels, B. and Auwerx, J. (1996) PPARalpha and PPARgamma activators direct a distinct tissuespecific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J., 15, 5336-5348.
    • (1996) EMBO J , vol.15 , pp. 5336-5348
    • Schoonjans, K.1    Peinado-Onsurbe, J.2    Lefebvre, A.M.3    Heyman, R.A.4    Briggs, M.5    Deeb, S.6    Staels, B.7    Auwerx, J.8
  • 164
    • 0038757610 scopus 로고    scopus 로고
    • Mitogenactivated protein kinases: A new therapeutic target in cardiac pathology
    • Ravingerova, T.; Barancik, M. and Strniskova, M. (2003) Mitogenactivated protein kinases: a new therapeutic target in cardiac pathology. Mol. Cell. Biochem., 247, 127-138.
    • (2003) Mol. Cell. Biochem , vol.247 , pp. 127-138
    • Ravingerova, T.1    Barancik, M.2    Strniskova, M.3
  • 165
    • 0942287345 scopus 로고    scopus 로고
    • Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response
    • Feingold, K.; Kim, M.S.; Shigenaga, J.; Moser, A. and Grunfeld, C. (2004) Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Am. J. Physiol. Endocrinol. Metab., 286, E201-207.
    • (2004) Am. J. Physiol. Endocrinol. Metab , vol.286
    • Feingold, K.1    Kim, M.S.2    Shigenaga, J.3    Moser, A.4    Grunfeld, C.5
  • 166
    • 0036791175 scopus 로고    scopus 로고
    • Myocardial dysfunction in the patient with sepsis. Curr. Opin. Crit
    • Krishnagopalan, S.; Kumar, A.; Parrillo, J.E. and Kumar, A. (2002) Myocardial dysfunction in the patient with sepsis. Curr. Opin. Crit. Care, 8, 376-388.
    • (2002) Care , vol.8 , pp. 376-388
    • Krishnagopalan, S.1    Kumar, A.2    Parrillo, J.E.3    Kumar, A.4
  • 167
    • 1042280330 scopus 로고    scopus 로고
    • Myocardial remodeling in viral heart disease: Possible interactions between inflammatory mediators and MMP-TIMP system
    • Pauschinger, M.; Chandrasekharan, K. and Schultheiss, H.P. (2004) Myocardial remodeling in viral heart disease: possible interactions between inflammatory mediators and MMP-TIMP system. Heart Fail Rev., 9, 21-31.
    • (2004) Heart Fail Rev , vol.9 , pp. 21-31
    • Pauschinger, M.1    Chandrasekharan, K.2    Schultheiss, H.P.3
  • 168
    • 17844377356 scopus 로고    scopus 로고
    • Inflammatory and anti-inflammatory cytokines in chronic heart failure: Potential therapeutic implications
    • Aukrust, P.; Gullestad, L.; Ueland, T.; Damas, J.K. and Yndestad, A. (2005) Inflammatory and anti-inflammatory cytokines in chronic heart failure: potential therapeutic implications. Ann. Med., 37, 74-85.
    • (2005) Ann. Med , vol.37 , pp. 74-85
    • Aukrust, P.1    Gullestad, L.2    Ueland, T.3    Damas, J.K.4    Yndestad, A.5
  • 169
    • 2442646648 scopus 로고    scopus 로고
    • Interleukin-6 and cardiovascular diseases
    • Kanda, T. and Takahashi, T. (2004) Interleukin-6 and cardiovascular diseases. Jpn. Heart J., 45, 183-193.
    • (2004) Jpn. Heart J , vol.45 , pp. 183-193
    • Kanda, T.1    Takahashi, T.2
  • 172
    • 0034601740 scopus 로고    scopus 로고
    • Cardiacspecific overexpression of tumor necrosis factor-alpha causes oxi-dative stress and contractile dysfunction in mouse diaphragm
    • Li, X.; Moody, M.R.; Engel, D.; Walker, S.; Clubb, F.J.Jr.; Sivasubramanian, N.; Mann, D.L. and Reid, M.B. (2000) Cardiacspecific overexpression of tumor necrosis factor-alpha causes oxi-dative stress and contractile dysfunction in mouse diaphragm. Circulation, 102, 1690-1696.
    • (2000) Circulation , vol.102 , pp. 1690-1696
    • Li, X.1    Moody, M.R.2    Engel, D.3    Walker, S.4    Clubb Jr., F.J.5    Sivasubramanian, N.6    Mann, D.L.7    Reid, M.B.8
  • 173
    • 10844250123 scopus 로고    scopus 로고
    • Insulin resistance and inflammatory activation in older patients with systolic and diastolic heart failure
    • Wisniacki, N.; Taylor, W.; Lye, M. and Wilding, J.P. (2005) Insulin resistance and inflammatory activation in older patients with systolic and diastolic heart failure. Heart, 91, 32-37.
    • (2005) Heart , vol.91 , pp. 32-37
    • Wisniacki, N.1    Taylor, W.2    Lye, M.3    Wilding, J.P.4
  • 174
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
    • Levine, B.; Kalman, J.; Mayer, L.; Fillit, H.M. and Packer, M. (1990) Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N. Engl. J. Med., 323, 236-241.
    • (1990) N. Engl. J. Med , vol.323 , pp. 236-241
    • Levine, B.1    Kalman, J.2    Mayer, L.3    Fillit, H.M.4    Packer, M.5
  • 176
    • 0030273548 scopus 로고    scopus 로고
    • Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension
    • Testa, M.; Yeh, M.; Lee, P.; Fanelli, R.; Loperfido, F.; Berman, J.W. and LeJemtel, T.H. (1996) Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension. J. Am. Coll. Cardiol., 28, 964-971.
    • (1996) J. Am. Coll. Cardiol , vol.28 , pp. 964-971
    • Testa, M.1    Yeh, M.2    Lee, P.3    Fanelli, R.4    Loperfido, F.5    Berman, J.W.6    Lejemtel, T.H.7
  • 177
    • 0029871896 scopus 로고    scopus 로고
    • Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the Studies of Left Ventricular Dysfunction (SOLVD). J. Am. Coll
    • Torre-Amione, G.; Kapadia, S.; Benedict, C.; Oral, H.; Young, J.B. and Mann, D.L. (1996) Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). J. Am. Coll. Cardiol., 27, 1201-1206.
    • (1996) Cardiol , vol.27 , pp. 1201-1206
    • Torre-Amione, G.1    Kapadia, S.2    Benedict, C.3    Oral, H.4    Young, J.B.5    Mann, D.L.6
  • 180
    • 27444441660 scopus 로고    scopus 로고
    • Arterial stiffness is related to systemic inflammation in essential hypertension
    • Mahmud, A. and Feely, J. (2005) Arterial stiffness is related to systemic inflammation in essential hypertension. Hypertension, 46, 1118-1122.
    • (2005) Hypertension , vol.46 , pp. 1118-1122
    • Mahmud, A.1    Feely, J.2
  • 181
    • 13544259939 scopus 로고    scopus 로고
    • Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertension
    • Bautista, L.E.; Vera, L.M.; Arenas, I.A. and Gamarra, G. (2005) Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertension. J. Hum. Hypertens., 19, 149-154.
    • (2005) J. Hum. Hypertens , vol.19 , pp. 149-154
    • Bautista, L.E.1    Vera, L.M.2    Arenas, I.A.3    Gamarra, G.4
  • 184
    • 4644231399 scopus 로고    scopus 로고
    • Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaBmediated promatrix metalloproteinase-9 activation
    • Rangaswami, H.; Bulbule, A. and Kundu, G.C. (2004) Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaBmediated promatrix metalloproteinase-9 activation. J. Biol. Chem., 279, 38921-38935.
    • (2004) J. Biol. Chem , vol.279 , pp. 38921-38935
    • Rangaswami, H.1    Bulbule, A.2    Kundu, G.C.3
  • 186
    • 1942484870 scopus 로고    scopus 로고
    • Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor- alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway
    • Ogata, T.; Miyauchi, T.; Sakai, S.; Takanashi, M.; Irukayama- Tomobe, Y. and Yamaguchi, I. (2004) Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor- alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway. J. Am. Coll. Cardiol., 43, 1481-1488.
    • (2004) J. Am. Coll. Cardiol , vol.43 , pp. 1481-1488
    • Ogata, T.1    Miyauchi, T.2    Sakai, S.3    Takanashi, M.4    Irukayama-Tomobe, Y.5    Yamaguchi, I.6
  • 187
    • 23944466382 scopus 로고    scopus 로고
    • Diastolic dysfunction in hypertensive hearts: Roles of perivascular inflammation and reactive myocardial fibrosis
    • Kai, H.; Kuwahara, F.; Tokuda, K. and Imaizumi, T. (2005) Diastolic dysfunction in hypertensive hearts: roles of perivascular inflammation and reactive myocardial fibrosis. Hypertens. Res., 28, 483-490.
    • (2005) Hypertens. Res , vol.28 , pp. 483-490
    • Kai, H.1    Kuwahara, F.2    Tokuda, K.3    Imaizumi, T.4
  • 190
    • 33751519338 scopus 로고    scopus 로고
    • Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome
    • Devaraj, S.; Chan, E. and Jialal, I. (2006) Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome. J. Clin. Endocrinol. Metab., 91, 4489-4496.
    • (2006) J. Clin. Endocrinol. Metab , vol.91 , pp. 4489-4496
    • Devaraj, S.1    Chan, E.2    Jialal, I.3
  • 192
    • 1642542466 scopus 로고    scopus 로고
    • Hypertensive myocardial fibrosis and diastolic dysfunction: Another model of inflammation?
    • Kuwahara, F.; Kai, H.; Tokuda, K.; Takeya, M.; Takeshita, A.; Egashira, K. and Imaizumi, T. (2004) Hypertensive myocardial fibrosis and diastolic dysfunction: another model of inflammation? Hypertension, 43, 739-745.
    • (2004) Hypertension , vol.43 , pp. 739-745
    • Kuwahara, F.1    Kai, H.2    Tokuda, K.3    Takeya, M.4    Takeshita, A.5    Egashira, K.6    Imaizumi, T.7
  • 194
    • 0038755661 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: Results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial
    • Chung, E.S.; Packer, M.; Lo, K.H.; Fasanmade, A.A. and Willerson, J.T. (2003) Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation, 107, 3133-3140.
    • (2003) Circulation , vol.107 , pp. 3133-3140
    • Chung, E.S.1    Packer, M.2    Lo, K.H.3    Fasanmade, A.A.4    Willerson, J.T.5
  • 195
    • 0030885575 scopus 로고    scopus 로고
    • Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling
    • Peraldi, P.; Xu, M. and Spiegelman, B.M. (1997) Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling. J. Clin. Invest., 100, 1863-1869.
    • (1997) J. Clin. Invest , vol.100 , pp. 1863-1869
    • Peraldi, P.1    Xu, M.2    Spiegelman, B.M.3
  • 196
    • 0033007231 scopus 로고    scopus 로고
    • Effect of peroxisome proliferator- activated receptor alpha activators on tumor necrosis factor expression in mice during endotoxemia
    • Hill, M.R.; Clarke, S.; Rodgers, K.; Thornhill, B.; Peters, J.M.; Gonzalez, F.J. and Gimble, J.M. (1999) Effect of peroxisome proliferator- activated receptor alpha activators on tumor necrosis factor expression in mice during endotoxemia. Infect. Immun., 67, 3488-3493.
    • (1999) Infect. Immun , vol.67 , pp. 3488-3493
    • Hill, M.R.1    Clarke, S.2    Rodgers, K.3    Thornhill, B.4    Peters, J.M.5    Gonzalez, F.J.6    Gimble, J.M.7
  • 197
    • 0034965596 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in inflammation control
    • Delerive, P.; Fruchart, J.C. and Staels, B. (2001) Peroxisome proliferator-activated receptors in inflammation control. J. Endocrinol., 169, 453-459.
    • (2001) J. Endocrinol , vol.169 , pp. 453-459
    • Delerive, P.1    Fruchart, J.C.2    Staels, B.3
  • 198
  • 199
    • 12344322946 scopus 로고    scopus 로고
    • Effect of peroxisome proliferator-activated receptor activators on tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes
    • Ye, P.; Fang, H.; Zhou, X.; He, Y.L. and Liu, Y.X. (2004) Effect of peroxisome proliferator-activated receptor activators on tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes. Chin. Med. Sci. J., 19, 243-247.
    • (2004) Chin. Med. Sci. J , vol.19 , pp. 243-247
    • Ye, P.1    Fang, H.2    Zhou, X.3    He, Y.L.4    Liu, Y.X.5
  • 201
    • 33646050605 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and the control of fatty acid oxidation in cardiac hypertrophy
    • Planavila, A.; Calvo, R.R. and Vazquez-Carrera, M. (2006) Peroxisome proliferator-activated receptors and the control of fatty acid oxidation in cardiac hypertrophy. Mini Rev. Med. Chem., 6, 357-363.
    • (2006) Mini Rev. Med. Chem , vol.6 , pp. 357-363
    • Planavila, A.1    Calvo, R.R.2    Vazquez-Carrera, M.3
  • 202
    • 0026781014 scopus 로고
    • Effects of weight reduction on blood lipids and lipoproteins: A meta-analysis
    • Dattilo, A.M. and Kris-Etherton, P.M. (1992) Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. Am. J. Clin. Nutr., 56, 320-328.
    • (1992) Am. J. Clin. Nutr , vol.56 , pp. 320-328
    • Dattilo, A.M.1    Kris-Etherton, P.M.2
  • 204
    • 0030051470 scopus 로고    scopus 로고
    • Effects of diet and exercise on common cardiovascular disease risk factors in moderately obese older women
    • Fox, A.A.; Thompson, J.L.; Butterfield, G.E.; Gylfadottir, U.; Moynihan, S. and Spiller, G. (1996) Effects of diet and exercise on common cardiovascular disease risk factors in moderately obese older women. Am. J. Clin. Nutr., 63, 225-233.
    • (1996) Am. J. Clin. Nutr , vol.63 , pp. 225-233
    • Fox, A.A.1    Thompson, J.L.2    Butterfield, G.E.3    Gylfadottir, U.4    Moynihan, S.5    Spiller, G.6
  • 205
    • 0031572160 scopus 로고    scopus 로고
    • Cardiac morphology and left ventricular function in normotensive morbidly obese patients with and without congestive heart failure, and effect of weight loss
    • Alpert, M.A.; Terry, B.E.; Mulekar, M.; Cohen, M.V.; Massey, C.V.; Fan, T.M.; Panayiotou, H. and Mukerji, V. (1997) Cardiac morphology and left ventricular function in normotensive morbidly obese patients with and without congestive heart failure, and effect of weight loss. Am. J. Cardiol., 80, 736-740.
    • (1997) Am. J. Cardiol , vol.80 , pp. 736-740
    • Alpert, M.A.1    Terry, B.E.2    Mulekar, M.3    Cohen, M.V.4    Massey, C.V.5    Fan, T.M.6    Panayiotou, H.7    Mukerji, V.8
  • 206
    • 0037333572 scopus 로고    scopus 로고
    • Associations of weight loss and changes in fat distribution with the remission of hypertension in a bi-ethnic cohort: The Atherosclerosis Risk in Communities Study
    • Juhaeri, Stevens, J.; Chambless, L.E.; Nieto, F.J.; Jones, D.; Schreiner, P.; Arnett, D. and Cai, J. (2003) Associations of weight loss and changes in fat distribution with the remission of hypertension in a bi-ethnic cohort: the Atherosclerosis Risk in Communities Study. Prev. Med., 36, 330-339.
    • (2003) Prev. Med , vol.36 , pp. 330-339
    • Juhaeri1    Stevens, J.2    Chambless, L.E.3    Nieto, F.J.4    Jones, D.5    Schreiner, P.6    Arnett, D.7    Cai, J.8
  • 207
    • 0036797764 scopus 로고    scopus 로고
    • Effects of obesity and weight loss on the expression of proteins involved in fatty acid metabolism in human adipose tissue
    • Fisher, R.M.; Hoffstedt, J.; Hotamisligil, G.S.; Thorne, A. and Ryden, M. (2002) Effects of obesity and weight loss on the expression of proteins involved in fatty acid metabolism in human adipose tissue. Int. J. Obes. Relat. Metab. Disord., 26, 1379-1385.
    • (2002) Int. J. Obes. Relat. Metab. Disord , vol.26 , pp. 1379-1385
    • Fisher, R.M.1    Hoffstedt, J.2    Hotamisligil, G.S.3    Thorne, A.4    Ryden, M.5
  • 208
    • 0035463106 scopus 로고    scopus 로고
    • Impact of weight reduction on early carotid atherosclerosis in obese premenopausal women
    • Mavri, A.; Stegnar, M.; Sentocnik, J.T. and Videcnik, V. (2001) Impact of weight reduction on early carotid atherosclerosis in obese premenopausal women. Obes. Res., 9, 511-516.
    • (2001) Obes. Res , vol.9 , pp. 511-516
    • Mavri, A.1    Stegnar, M.2    Sentocnik, J.T.3    Videcnik, V.4
  • 209
    • 0030934629 scopus 로고    scopus 로고
    • The beneficial effects of modest weight loss on cardiovascular risk factors
    • Van Gaal, L.F.; Wauters, M.A. and De Leeuw, I.H. (1997) The beneficial effects of modest weight loss on cardiovascular risk factors. Int. J. Obes. Relat. Metab. Disord., 21(Suppl 1), S5-9.
    • (1997) Int. J. Obes. Relat. Metab. Disord , vol.21 , Issue.SUPPL. 1
    • van Gaal, L.F.1    Wauters, M.A.2    de Leeuw, I.H.3
  • 210
    • 0036264984 scopus 로고    scopus 로고
    • Markers of chronic inflammation and obesity: A prospective study on the reversibility of this association in middle-aged women undergoing weight loss by surgical intervention
    • Laimer, M.; Ebenbichler, C.F.; Kaser, S.; Sandhofer, A.; Weiss, H.; Nehoda, H.; Aigner, F. and Patsch, J.R. (2002) Markers of chronic inflammation and obesity: a prospective study on the reversibility of this association in middle-aged women undergoing weight loss by surgical intervention. Int. J. Obes. Relat. Metab. Disord., 26, 659-662.
    • (2002) Int. J. Obes. Relat. Metab. Disord , vol.26 , pp. 659-662
    • Laimer, M.1    Ebenbichler, C.F.2    Kaser, S.3    Sandhofer, A.4    Weiss, H.5    Nehoda, H.6    Aigner, F.7    Patsch, J.R.8
  • 212
    • 21244472681 scopus 로고    scopus 로고
    • Effects of marked weight loss on plasma levels of adiponectin, markers of chronic subclinical inflammation and insulin resistance in morbidly obese women
    • Kopp, H.P.; Krzyzanowska, K.; Mohlig, M.; Spranger, J.; Pfeiffer, A.F. and Schernthaner, G. (2005) Effects of marked weight loss on plasma levels of adiponectin, markers of chronic subclinical inflammation and insulin resistance in morbidly obese women. Int. J. Obes. (Lond), 29, 766-771.
    • (2005) Int. J. Obes. (Lond) , vol.29 , pp. 766-771
    • Kopp, H.P.1    Krzyzanowska, K.2    Mohlig, M.3    Spranger, J.4    Pfeiffer, A.F.5    Schernthaner, G.6
  • 214
    • 0034068984 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Association with obesity and insulin resistance, and influence of weight loss
    • Luyckx, F.H.; Lefebvre, P.J. and Scheen, A.J. (2000) Nonalcoholic steatohepatitis: association with obesity and insulin resistance, and influence of weight loss. Diabetes Metab., 26, 98-106.
    • (2000) Diabetes Metab , vol.26 , pp. 98-106
    • Luyckx, F.H.1    Lefebvre, P.J.2    Scheen, A.J.3
  • 215
    • 0035091701 scopus 로고    scopus 로고
    • Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues
    • Way, J.M.; Harrington, W.W.; Brown, K.K.; Gottschalk, W.K.; Sundseth, S.S.; Mansfield, T.A.; Ramachandran, R.K.; Willson, T.M. and Kliewer, S.A. (2001) Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues. Endocrinology, 142, 1269-1277.
    • (2001) Endocrinology , vol.142 , pp. 1269-1277
    • Way, J.M.1    Harrington, W.W.2    Brown, K.K.3    Gottschalk, W.K.4    Sundseth, S.S.5    Mansfield, T.A.6    Ramachandran, R.K.7    Willson, T.M.8    Kliewer, S.A.9
  • 216
    • 0037013201 scopus 로고    scopus 로고
    • Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator- activated receptor alpha and gamma ligands
    • Sato, O.; Kuriki, C.; Fukui, Y. and Motojima, K. (2002) Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator- activated receptor alpha and gamma ligands. J. Biol. Chem., 277, 15703-15711.
    • (2002) J. Biol. Chem , vol.277 , pp. 15703-15711
    • Sato, O.1    Kuriki, C.2    Fukui, Y.3    Motojima, K.4
  • 217
    • 0036291635 scopus 로고    scopus 로고
    • Selective cooperation between fatty acid binding proteins and peroxisome proliferator- activated receptors in regulating transcription
    • Tan, N.S.; Shaw, N.S.; Vinckenbosch, N.; Liu, P.; Yasmin, R.; Desvergne, B.; Wahli, W. and Noy, N. (2002) Selective cooperation between fatty acid binding proteins and peroxisome proliferator- activated receptors in regulating transcription. Mol. Cell. Biol., 22, 5114-5127.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 5114-5127
    • Tan, N.S.1    Shaw, N.S.2    Vinckenbosch, N.3    Liu, P.4    Yasmin, R.5    Desvergne, B.6    Wahli, W.7    Noy, N.8
  • 219
    • 0033973843 scopus 로고    scopus 로고
    • Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency
    • Miles, P.D.; Barak, Y.; He, W.; Evans, R.M. and Olefsky, J.M. (2000) Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. J. Clin. Invest., 105, 287-292.
    • (2000) J. Clin. Invest , vol.105 , pp. 287-292
    • Miles, P.D.1    Barak, Y.2    He, W.3    Evans, R.M.4    Olefsky, J.M.5
  • 222
    • 17044430286 scopus 로고    scopus 로고
    • PPARgamma in endothelial cells influences high fat diet-induced hypertension
    • Nicol, C.J.; Adachi, M.; Akiyama, T.E. and Gonzalez, F.J. (2005) PPARgamma in endothelial cells influences high fat diet-induced hypertension. Am. J. Hypertens., 18, 549-556.
    • (2005) Am. J. Hypertens , vol.18 , pp. 549-556
    • Nicol, C.J.1    Adachi, M.2    Akiyama, T.E.3    Gonzalez, F.J.4
  • 223
    • 69249090213 scopus 로고    scopus 로고
    • Rosiglitazone increases the expression of peroxisome proliferatoractivated receptor-gamma target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation
    • Muhlhausler, B.S.; Morrison, J.L. and McMillen, I.C. (2009) Rosiglitazone increases the expression of peroxisome proliferatoractivated receptor-gamma target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation. Endocrinology, 150, 4287-4294.
    • (2009) Endocrinology , vol.150 , pp. 4287-4294
    • Muhlhausler, B.S.1    Morrison, J.L.2    McMillen, I.C.3
  • 224
    • 49849086021 scopus 로고    scopus 로고
    • The peroxisome proliferator- activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator-activated receptor-alphadependent manner in vitro and in vivo in mice
    • Orasanu, G.; Ziouzenkova, O.; Devchand, P.R.; Nehra, V.; Hamdy, O.; Horton, E.S. and Plutzky, J. (2008) The peroxisome proliferator- activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator-activated receptor-alphadependent manner in vitro and in vivo in mice. J. Am. Coll. Cardiol., 52, 869-881.
    • (2008) J. Am. Coll. Cardiol , vol.52 , pp. 869-881
    • Orasanu, G.1    Ziouzenkova, O.2    Devchand, P.R.3    Nehra, V.4    Hamdy, O.5    Horton, E.S.6    Plutzky, J.7
  • 225
    • 0242332284 scopus 로고    scopus 로고
    • Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: A retrospective cohort study
    • Delea, T.E.; Edelsberg, J.S.; Hagiwara, M.; Oster, G. and Phillips, L.S. (2003) Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study. Diabetes Care, 26, 2983-2989.
    • (2003) Diabetes Care , vol.26 , pp. 2983-2989
    • Delea, T.E.1    Edelsberg, J.S.2    Hagiwara, M.3    Oster, G.4    Phillips, L.S.5
  • 226
    • 23844472901 scopus 로고    scopus 로고
    • Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption. Nat
    • Guan, Y.; Hao, C.; Cha, D.R.; Rao, R.; Lu, W.; Kohan, D.E.; Magnuson, M.A.; Redha, R.; Zhang, Y. and Breyer, M.D. (2005) Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption. Nat. Med., 11, 861-866.
    • (2005) Med , vol.11 , pp. 861-866
    • Guan, Y.1    Hao, C.2    Cha, D.R.3    Rao, R.4    Lu, W.5    Kohan, D.E.6    Magnuson, M.A.7    Redha, R.8    Zhang, Y.9    Breyer, M.D.10
  • 227
    • 0037302089 scopus 로고    scopus 로고
    • The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: A placebocontrolled randomized clinical trial
    • Caballero, A.E.; Saouaf, R.; Lim, S.C.; Hamdy, O.; Abou-Elenin, K.; O'Connor, C.; Logerfo, F.W.; Horton, E.S. and Veves, A. (2003) The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: a placebocontrolled randomized clinical trial. Metabolism, 52, 173-180.
    • (2003) Metabolism , vol.52 , pp. 173-180
    • Caballero, A.E.1    Saouaf, R.2    Lim, S.C.3    Hamdy, O.4    Abou-Elenin, K.5    O'Connor, C.6    Logerfo, F.W.7    Horton, E.S.8    Veves, A.9
  • 229
    • 35148890313 scopus 로고    scopus 로고
    • PROactive 07: Pioglitazone in the treatment of type 2 diabetes: Results of the PROactive study. Vasc. Health
    • Erdmann, E.; Dormandy, J.; Wilcox, R.; Massi-Benedetti, M. and Charbonnel, B. (2007) PROactive 07: pioglitazone in the treatment of type 2 diabetes: results of the PROactive study. Vasc. Health Risk Manag., 3, 355-370.
    • (2007) Risk Manag , vol.3 , pp. 355-370
    • Erdmann, E.1    Dormandy, J.2    Wilcox, R.3    Massi-Benedetti, M.4    Charbonnel, B.5
  • 231
    • 31744435022 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma regulates angiotensin II-stimulated phosphatidylinositol 3-kinase and mitogenactivated protein kinase in blood vessels in vivo
    • Benkirane, K.; Viel, E.C.; Amiri, F. and Schiffrin, E.L. (2006) Peroxisome proliferator-activated receptor gamma regulates angiotensin II-stimulated phosphatidylinositol 3-kinase and mitogenactivated protein kinase in blood vessels in vivo. Hypertension, 47, 102-108.
    • (2006) Hypertension , vol.47 , pp. 102-108
    • Benkirane, K.1    Viel, E.C.2    Amiri, F.3    Schiffrin, E.L.4
  • 234
  • 235
    • 0036833805 scopus 로고    scopus 로고
    • A comparison of the effects of rosiglitazone and glyburide on cardiovascular function and glycemic control in patients with type 2 diabetes. Diabetes
    • St John Sutton, M.; Rendell, M.; Dandona, P.; Dole, J.F.; Murphy, K.; Patwardhan, R.; Patel, J. and Freed, M. (2002) A comparison of the effects of rosiglitazone and glyburide on cardiovascular function and glycemic control in patients with type 2 diabetes. Diabetes Care, 25, 2058-2064.
    • (2002) Care , vol.25 , pp. 2058-2064
    • St John Sutton, M.1    Rendell, M.2    Dandona, P.3    Dole, J.F.4    Murphy, K.5    Patwardhan, R.6    Patel, J.7    Freed, M.8
  • 237
    • 67149146438 scopus 로고    scopus 로고
    • Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): A multicentre, randomised, open-label trial
    • Home, P.D.; Pocock, S.J.; Beck-Nielsen, H.; Curtis, P.S.; Gomis, R.; Hanefeld, M.; Jones, N.P.; Komajda, M.; McMurray, J.J. and Team, R.S. (2009) Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet, 373, 2125-2135.
    • (2009) Lancet , vol.373 , pp. 2125-2135
    • Home, P.D.1    Pocock, S.J.2    Beck-Nielsen, H.3    Curtis, P.S.4    Gomis, R.5    Hanefeld, M.6    Jones, N.P.7    Komajda, M.8    McMurray, J.J.9    Team10
  • 238
    • 22644438570 scopus 로고    scopus 로고
    • Pioglitazone initiation and subsequent hospitalization for congestive heart failure
    • Karter, A.J.; Ahmed, A.T.; Liu, J.; Moffet, H.H. and Parker, M.M. (2005) Pioglitazone initiation and subsequent hospitalization for congestive heart failure. Diabet. Med., 22, 986-993.
    • (2005) Diabet. Med , vol.22 , pp. 986-993
    • Karter, A.J.1    Ahmed, A.T.2    Liu, J.3    Moffet, H.H.4    Parker, M.M.5
  • 239
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen, S.E. and Wolski, K. (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N. Engl. J. Med., 356, 2457-2471.
    • (2007) N. Engl. J. Med , vol.356 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 241
    • 2442451618 scopus 로고    scopus 로고
    • Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity
    • Schupp, M.; Janke, J.; Clasen, R.; Unger, T. and Kintscher, U. (2004) Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation, 109, 2054-2057.
    • (2004) Circulation , vol.109 , pp. 2054-2057
    • Schupp, M.1    Janke, J.2    Clasen, R.3    Unger, T.4    Kintscher, U.5
  • 242
    • 0035797865 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes
    • Yamamoto, K.; Ohki, R.; Lee, R.T.; Ikeda, U. and Shimada, K. (2001) Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes. Circulation, 104, 1670-1675.
    • (2001) Circulation , vol.104 , pp. 1670-1675
    • Yamamoto, K.1    Ohki, R.2    Lee, R.T.3    Ikeda, U.4    Shimada, K.5
  • 244
    • 33747438362 scopus 로고    scopus 로고
    • Angiotensin type 1 receptor antagonists induce human in invitro adipogenesis through peroxisome proliferator-activated receptor-gamma activation
    • Janke, J.; Schupp, M.; Engeli, S.; Gorzelniak, K.; Boschmann, M.; Sauma, L.; Nystrom, F.H.; Jordan, J.; Luft, F.C. and Sharma, A.M. (2006) Angiotensin type 1 receptor antagonists induce human in invitro adipogenesis through peroxisome proliferator-activated receptor-gamma activation. J. Hypertens., 24, 1809-1816.
    • (2006) J. Hypertens , vol.24 , pp. 1809-1816
    • Janke, J.1    Schupp, M.2    Engeli, S.3    Gorzelniak, K.4    Boschmann, M.5    Sauma, L.6    Nystrom, F.H.7    Jordan, J.8    Luft, F.C.9    Sharma, A.M.10
  • 245
    • 33747039772 scopus 로고    scopus 로고
    • The effect of telmisartan on glucose and lipid metabolism in nondiabetic, insulin-resistant subjects
    • Nagel, J.M.; Tietz, A.B.; Goke, B. and Parhofer, K.G. (2006) The effect of telmisartan on glucose and lipid metabolism in nondiabetic, insulin-resistant subjects. Metabolism, 55, 1149-1154.
    • (2006) Metabolism , vol.55 , pp. 1149-1154
    • Nagel, J.M.1    Tietz, A.B.2    Goke, B.3    Parhofer, K.G.4
  • 246
    • 67649839953 scopus 로고    scopus 로고
    • Effect of the dual peroxisome proliferatoractivated receptor-alpha/gamma agonist aleglitazar on risk of cardiovascular disease in patients with type 2 diabetes (SYNCHRONY): A phase II, randomised, dose-ranging study
    • Henry, R.R.; Lincoff, A.M.; Mudaliar, S.; Rabbia, M.; Chognot, C. and Herz, M. (2009) Effect of the dual peroxisome proliferatoractivated receptor-alpha/gamma agonist aleglitazar on risk of cardiovascular disease in patients with type 2 diabetes (SYNCHRONY): a phase II, randomised, dose-ranging study. Lancet, 374, 126-135.
    • (2009) Lancet , vol.374 , pp. 126-135
    • Henry, R.R.1    Lincoff, A.M.2    Mudaliar, S.3    Rabbia, M.4    Chognot, C.5    Herz, M.6
  • 247
    • 47649113067 scopus 로고    scopus 로고
    • The endocannabinoid system and cardiometabolic risk
    • Szmitko, P.E. and Verma, S. (2008) The endocannabinoid system and cardiometabolic risk. Atherosclerosis, 199, 248-256.
    • (2008) Atherosclerosis , vol.199 , pp. 248-256
    • Szmitko, P.E.1    Verma, S.2
  • 248
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial
    • and Group, R.I.-N.A.S
    • Pi-Sunyer, F.X.; Aronne, L.J.; Heshmati, H.M.; Devin, J.; Rosenstock, J. and Group, R.I.-N.A.S. (2006) Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA, 295, 761-775.
    • (2006) JAMA , vol.295 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3    Devin, J.4    Rosenstock, J.5
  • 249
    • 0036839367 scopus 로고    scopus 로고
    • Anatomy of the mitral valve
    • Ho, S.Y. (2002) Anatomy of the mitral valve. Heart, 88 (Suppl 4), iv5-10.
    • (2002) Heart , vol.88 , Issue.SUPPL. 4
    • Ho, S.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.