-
1
-
-
47649117375
-
-
World Health Organization. Obesity and Overweight Fact Sheet No. 311; 2006. http://www.who.int/mediacentre/factsheets/fs311/en/print.html [accessed September 8, 2007].
-
World Health Organization. Obesity and Overweight Fact Sheet No. 311; 2006. http://www.who.int/mediacentre/factsheets/fs311/en/print.html [accessed September 8, 2007].
-
-
-
-
2
-
-
27644457743
-
-
Yusuf S, Hawken S, Ounpuu S, et al. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 2005;366:1640-9
-
Yusuf S, Hawken S, Ounpuu S, et al. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 2005;366:1640-9
-
-
-
-
3
-
-
18044366410
-
Adipokines: molecular links between obesity and atheroslcerosis
-
Lau D.C., Dhillon B., Yan H., Szmitko P.E., and Verma S. Adipokines: molecular links between obesity and atheroslcerosis. Am J Physiol Heart Circ Physiol 288 (2005) H2031-H2041
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
-
-
Lau, D.C.1
Dhillon, B.2
Yan, H.3
Szmitko, P.E.4
Verma, S.5
-
5
-
-
32444440208
-
The emerging role of the endocannabinoid system in endocrine regulation and energy balance
-
Pagotto U., Marsicano G., Cota D., Lutz B., and Pasquali R. The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev 27 (2006) 73-100
-
(2006)
Endocr Rev
, vol.27
, pp. 73-100
-
-
Pagotto, U.1
Marsicano, G.2
Cota, D.3
Lutz, B.4
Pasquali, R.5
-
6
-
-
33947489961
-
Isolation, structure and partial synthesis of an active constituent of hashish
-
Gaoni Y., and Mechoulam R. Isolation, structure and partial synthesis of an active constituent of hashish. J Am Chem Soc 86 (1964) 1646-1647
-
(1964)
J Am Chem Soc
, vol.86
, pp. 1646-1647
-
-
Gaoni, Y.1
Mechoulam, R.2
-
7
-
-
33748703859
-
The endocannabinoid system as an emerging target of pharmacotherapy
-
Pacher P., Batkai S., and Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 58 (2006) 389-462
-
(2006)
Pharmacol Rev
, vol.58
, pp. 389-462
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
8
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda L.A., Lolait S.J., Brownstein M.J., Young A.C., and Bonner T.I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346 (1990) 561-564
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
9
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S., Thomas K.L., and Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365 (1993) 61-65
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
10
-
-
0037423029
-
Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor
-
Fride E., Foox A., Rosenberg E., et al. Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor. Eur J Pharmacol 461 (2003) 27-34
-
(2003)
Eur J Pharmacol
, vol.461
, pp. 27-34
-
-
Fride, E.1
Foox, A.2
Rosenberg, E.3
-
12
-
-
0023914862
-
Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model
-
Howlett A.C., Johnson M.R., Melvin L.S., and Milne G.M. Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model. Mol Pharmacol 33 (1988) 297-302
-
(1988)
Mol Pharmacol
, vol.33
, pp. 297-302
-
-
Howlett, A.C.1
Johnson, M.R.2
Melvin, L.S.3
Milne, G.M.4
-
13
-
-
0035019372
-
Cannabinoids activate p38 mitogen-activated protein kinases through CB1 receptors in hippocampus
-
Derkinderen P., Ledent C., Parmentier M., and Girault J.A. Cannabinoids activate p38 mitogen-activated protein kinases through CB1 receptors in hippocampus. J Neurochem 77 (2001) 957-960
-
(2001)
J Neurochem
, vol.77
, pp. 957-960
-
-
Derkinderen, P.1
Ledent, C.2
Parmentier, M.3
Girault, J.A.4
-
14
-
-
0030890230
-
Induction of interleukin-2 receptor alpha gene by delta9-tetrahydrocannabinoid is mediated by nuclear factor kappaB and CBI cannabinoid receptor
-
Daaka Y., Zhu W., Friedman H., and Klein T.W. Induction of interleukin-2 receptor alpha gene by delta9-tetrahydrocannabinoid is mediated by nuclear factor kappaB and CBI cannabinoid receptor. DNA Cell Biol 16 (1997) 301-309
-
(1997)
DNA Cell Biol
, vol.16
, pp. 301-309
-
-
Daaka, Y.1
Zhu, W.2
Friedman, H.3
Klein, T.W.4
-
15
-
-
0033806918
-
The CB1 cannabinoid receptor is coupled to the activation of c-JUN N-terminal kinase
-
Rueda D., Galve-Roperh I., Haro A., and Guzman M. The CB1 cannabinoid receptor is coupled to the activation of c-JUN N-terminal kinase. Mol Pharmacol 58 (2000) 814-820
-
(2000)
Mol Pharmacol
, vol.58
, pp. 814-820
-
-
Rueda, D.1
Galve-Roperh, I.2
Haro, A.3
Guzman, M.4
-
16
-
-
0037184060
-
Cannabinoids protect astrocytes from ceramide-induced apoptosis through the phosphatidylinositol 3-kinase/protein kinase B pathway
-
Gomez Del Pulgar T., De Ceballos M.L., Guzman M., and Velasco G. Cannabinoids protect astrocytes from ceramide-induced apoptosis through the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem 277 (2002) 36527-36533
-
(2002)
J Biol Chem
, vol.277
, pp. 36527-36533
-
-
Gomez Del Pulgar, T.1
De Ceballos, M.L.2
Guzman, M.3
Velasco, G.4
-
18
-
-
20944436157
-
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
-
Osei-Hyiaman D., DePetrillo M., Pacher P., et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 115 (2005) 1298-1305
-
(2005)
J Clin Invest
, vol.115
, pp. 1298-1305
-
-
Osei-Hyiaman, D.1
DePetrillo, M.2
Pacher, P.3
-
19
-
-
0035010955
-
Cannabinoids and the gastrointestinal tract
-
Pertwee R.G. Cannabinoids and the gastrointestinal tract. Gut 48 (2001) 859-867
-
(2001)
Gut
, vol.48
, pp. 859-867
-
-
Pertwee, R.G.1
-
21
-
-
85047690626
-
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
Cota D., Marsicano G., Tschoep M., et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 112 (2003) 423-431
-
(2003)
J Clin Invest
, vol.112
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschoep, M.3
-
22
-
-
0034653517
-
Functional CB1 cannabinoid receptors in human vascular endothelial cells
-
Liu J., Gao B., Mirshahi F., et al. Functional CB1 cannabinoid receptors in human vascular endothelial cells. Biochem J 346 (2000) 835-840
-
(2000)
Biochem J
, vol.346
, pp. 835-840
-
-
Liu, J.1
Gao, B.2
Mirshahi, F.3
-
24
-
-
26844504226
-
Identification and functional characterization of brainstem cannabinoid CB2 receptors
-
Van Sickle M.D., Duncan M., Kingsley P.J., et al. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 310 (2005) 329-332
-
(2005)
Science
, vol.310
, pp. 329-332
-
-
Van Sickle, M.D.1
Duncan, M.2
Kingsley, P.J.3
-
25
-
-
33845318626
-
Presence of the cannabinoid receptors, CB1 and CB2, in human omental and subcutaneous adipocytes
-
Roche R., Hoareau L., Bes-Houtmann S., et al. Presence of the cannabinoid receptors, CB1 and CB2, in human omental and subcutaneous adipocytes. Histochem Cell Biol 126 (2006) 177-187
-
(2006)
Histochem Cell Biol
, vol.126
, pp. 177-187
-
-
Roche, R.1
Hoareau, L.2
Bes-Houtmann, S.3
-
26
-
-
0037365941
-
Inhibition of tumour angiogenesis by cannabinoids
-
Blazquez C., Casanova M.L., Planas A., et al. Inhibition of tumour angiogenesis by cannabinoids. FASEB J 17 (2003) 529-531
-
(2003)
FASEB J
, vol.17
, pp. 529-531
-
-
Blazquez, C.1
Casanova, M.L.2
Planas, A.3
-
27
-
-
0036669295
-
Tetrahyrocannabinol and endocannabinoids in feeding and appetite
-
Berry E.M., and Mechoulam R. Tetrahyrocannabinol and endocannabinoids in feeding and appetite. Pharmacol Ther 95 (2002) 185-190
-
(2002)
Pharmacol Ther
, vol.95
, pp. 185-190
-
-
Berry, E.M.1
Mechoulam, R.2
-
29
-
-
0036361973
-
9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine
-
9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine. Pharmacol Biochem Behav 71 (2002) 333-340
-
(2002)
Pharmacol Biochem Behav
, vol.71
, pp. 333-340
-
-
Williams, C.M.1
Kirkham, T.C.2
-
31
-
-
0022900093
-
Behavioral analysis of marijuana effects on food intake in humans
-
Foltin R.W., Brady J.V., and Fischman M.W. Behavioral analysis of marijuana effects on food intake in humans. Pharmacol Biochem Behav 25 (1986) 577-582
-
(1986)
Pharmacol Biochem Behav
, vol.25
, pp. 577-582
-
-
Foltin, R.W.1
Brady, J.V.2
Fischman, M.W.3
-
32
-
-
0032936642
-
Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors
-
Williams C.M., and Kirkham T.C. Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. Psychopharmacology 143 (1999) 315-317
-
(1999)
Psychopharmacology
, vol.143
, pp. 315-317
-
-
Williams, C.M.1
Kirkham, T.C.2
-
33
-
-
0035984946
-
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol
-
Kirkham T.C., Williams C.M., Fezza F., and Di Marzo V. Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol 136 (2002) 550-557
-
(2002)
Br J Pharmacol
, vol.136
, pp. 550-557
-
-
Kirkham, T.C.1
Williams, C.M.2
Fezza, F.3
Di Marzo, V.4
-
34
-
-
0035848818
-
Leptin-regulated endocannabinoids are involved in maintaining food intake
-
Di Marzo V., Goparaju S.K., Wang L., et al. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 410 (2001) 822-825
-
(2001)
Nature
, vol.410
, pp. 822-825
-
-
Di Marzo, V.1
Goparaju, S.K.2
Wang, L.3
-
35
-
-
0032541111
-
Appetite suppression and weight loss after the cannabinoid antagonist SR141716
-
Colombo G., Agabio R., Diaz G., et al. Appetite suppression and weight loss after the cannabinoid antagonist SR141716. Life Sci 63 (1998) L113-L117
-
(1998)
Life Sci
, vol.63
-
-
Colombo, G.1
Agabio, R.2
Diaz, G.3
-
36
-
-
0037374766
-
The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
-
Bensaid M., Gary-Bobo M., Esclangon A., et al. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol Pharmacol 63 (2003) 908-914
-
(2003)
Mol Pharmacol
, vol.63
, pp. 908-914
-
-
Bensaid, M.1
Gary-Bobo, M.2
Esclangon, A.3
-
37
-
-
1842866963
-
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
-
Ravinet-Trillou C., Delgorge C., Menet C., Arnone M., and Soubrie P. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 28 (2004) 640-648
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 640-648
-
-
Ravinet-Trillou, C.1
Delgorge, C.2
Menet, C.3
Arnone, M.4
Soubrie, P.5
-
38
-
-
24644500204
-
The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance
-
Jbilo O., Ravinet-Trillou C., Arnone M., et al. The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance. FASEB J 19 (2005) 1567-1569
-
(2005)
FASEB J
, vol.19
, pp. 1567-1569
-
-
Jbilo, O.1
Ravinet-Trillou, C.2
Arnone, M.3
-
39
-
-
25844460609
-
Activation of the peripheral endocannabinoid system in human obesity
-
Engeli S., Bohnke J., Feldpausch M., et al. Activation of the peripheral endocannabinoid system in human obesity. Diabetes 54 (2005) 2838-2843
-
(2005)
Diabetes
, vol.54
, pp. 2838-2843
-
-
Engeli, S.1
Bohnke, J.2
Feldpausch, M.3
-
40
-
-
33947606528
-
Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men
-
Cote M., Matias I., Lemieux I., et al. Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. Int J Obese (Lond) 31 (2007) 692-699
-
(2007)
Int J Obese (Lond)
, vol.31
, pp. 692-699
-
-
Cote, M.1
Matias, I.2
Lemieux, I.3
-
41
-
-
33845522074
-
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity
-
Bluher M., Engeli S., Kloting N., et al. Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity. Diabetes 55 (2006) 3053-3060
-
(2006)
Diabetes
, vol.55
, pp. 3053-3060
-
-
Bluher, M.1
Engeli, S.2
Kloting, N.3
-
42
-
-
17844411014
-
Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH)
-
Sipe J.C., Waalen J., Gerber A., and Beutler E. Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH). Int J Obes Relat Metab Disord 29 (2005) 755-759
-
(2005)
Int J Obes Relat Metab Disord
, vol.29
, pp. 755-759
-
-
Sipe, J.C.1
Waalen, J.2
Gerber, A.3
Beutler, E.4
-
43
-
-
34249671248
-
Association between cannabinoid type-1 receptor polymorphism and body mass index in a southern Italian population
-
Gazzero P., Caruso M.G., Notarnicola M., et al. Association between cannabinoid type-1 receptor polymorphism and body mass index in a southern Italian population. Int J Obes (Lond) 31 (2007) 908-912
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 908-912
-
-
Gazzero, P.1
Caruso, M.G.2
Notarnicola, M.3
-
44
-
-
19444369394
-
Blood pressure regulation by endocannabinoids and their receptors
-
Pacher P., Batkai S., and Kunos G. Blood pressure regulation by endocannabinoids and their receptors. Neuropharmacology 48 (2005) 1130-1138
-
(2005)
Neuropharmacology
, vol.48
, pp. 1130-1138
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
45
-
-
0029055851
-
Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide
-
Varga K., Lake K., Martin B.R., and Kunos G. Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. Eur J Pharmacol 278 (1995) 279-283
-
(1995)
Eur J Pharmacol
, vol.278
, pp. 279-283
-
-
Varga, K.1
Lake, K.2
Martin, B.R.3
Kunos, G.4
-
46
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent C., Valverde O., Cossu G., et al. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 383 (1999) 401-404
-
(1999)
Science
, vol.383
, pp. 401-404
-
-
Ledent, C.1
Valverde, O.2
Cossu, G.3
-
47
-
-
0038796906
-
The peripheral sympathetic nervous system is the major target of cannabinoids in eliciting cardiovascular depression
-
Niederhoffer N., Schmid K., and Szabo B. The peripheral sympathetic nervous system is the major target of cannabinoids in eliciting cardiovascular depression. Naunyn Schmiedebergs Arch Pharmacol 367 (2003) 434-443
-
(2003)
Naunyn Schmiedebergs Arch Pharmacol
, vol.367
, pp. 434-443
-
-
Niederhoffer, N.1
Schmid, K.2
Szabo, B.3
-
48
-
-
0030798335
-
physiological actions of anandamide in the vasculature of the rat kidney
-
Deutsch D.G., Goligorsky M.S., Schmid P.C., et al. physiological actions of anandamide in the vasculature of the rat kidney. J Clin Invest 100 (1997) 1538-1546
-
(1997)
J Clin Invest
, vol.100
, pp. 1538-1546
-
-
Deutsch, D.G.1
Goligorsky, M.S.2
Schmid, P.C.3
-
49
-
-
0031823187
-
Platelet- and macrophage-derived endogenouscannabinoids are involved in endotoxin-induced hypotension
-
Varga K., Wagner J.A., Bridgen D.T., and Kunos G. Platelet- and macrophage-derived endogenouscannabinoids are involved in endotoxin-induced hypotension. FASEB J 12 (1998) 1035-1044
-
(1998)
FASEB J
, vol.12
, pp. 1035-1044
-
-
Varga, K.1
Wagner, J.A.2
Bridgen, D.T.3
Kunos, G.4
-
50
-
-
0031284976
-
Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock
-
Wagner J.A., Varga K., Ellis E.F., et al. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. Nature 390 (1997) 518-521
-
(1997)
Nature
, vol.390
, pp. 518-521
-
-
Wagner, J.A.1
Varga, K.2
Ellis, E.F.3
-
51
-
-
0035203968
-
Endogenous cannabinoids mediate hypotension after experimental myocardial infarction
-
Wagner J.A., Hu K., Bauersachs J., et al. Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. J Am Coll Cardiol 38 (2001) 2048-2054
-
(2001)
J Am Coll Cardiol
, vol.38
, pp. 2048-2054
-
-
Wagner, J.A.1
Hu, K.2
Bauersachs, J.3
-
52
-
-
20844454912
-
Endocannabinoids acting at CB1 receptors regulate cardiovascular function in hypertension
-
Batkai S., Pacher P., Osei-Hyiaman D., et al. Endocannabinoids acting at CB1 receptors regulate cardiovascular function in hypertension. Circulation 110 (2004) 1996-2002
-
(2004)
Circulation
, vol.110
, pp. 1996-2002
-
-
Batkai, S.1
Pacher, P.2
Osei-Hyiaman, D.3
-
53
-
-
0142055947
-
New markers of inflammation and endothelial cell activation
-
Szmitko P.E., Wang C.H., Weisel R.D., et al. New markers of inflammation and endothelial cell activation. Circulation 108 (2003) 1917-1923
-
(2003)
Circulation
, vol.108
, pp. 1917-1923
-
-
Szmitko, P.E.1
Wang, C.H.2
Weisel, R.D.3
-
54
-
-
17144400758
-
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
-
Steffens S., Veillard N.R., Arnaud C., et al. Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice. Nature 434 (2005) 782-786
-
(2005)
Nature
, vol.434
, pp. 782-786
-
-
Steffens, S.1
Veillard, N.R.2
Arnaud, C.3
-
55
-
-
33644593422
-
Does cannabis hold the key to treating cardiometabolic disease?
-
Szmitko P.E., and Verma S. Does cannabis hold the key to treating cardiometabolic disease?. Nat Clin Pract Cardiovasc Med 3 (2006) 116-117
-
(2006)
Nat Clin Pract Cardiovasc Med
, vol.3
, pp. 116-117
-
-
Szmitko, P.E.1
Verma, S.2
-
56
-
-
33744986319
-
Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin
-
Perwitz N., Fasshauer M., and Klein J. Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin. Horm Metab Res 38 (2006) 356-358
-
(2006)
Horm Metab Res
, vol.38
, pp. 356-358
-
-
Perwitz, N.1
Fasshauer, M.2
Klein, J.3
-
57
-
-
0037374766
-
The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats in cultured adipocyte cells
-
Bensaid M., Gary-Bobo M., Esclangon A., et al. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats in cultured adipocyte cells. Mol Pharmacol 63 (2003) 908-914
-
(2003)
Mol Pharmacol
, vol.63
, pp. 908-914
-
-
Bensaid, M.1
Gary-Bobo, M.2
Esclangon, A.3
-
58
-
-
25844451605
-
Cocaine- and amphetamine-related transcript peptide is involved in the orexigenic effect of endogenous anandamide
-
Osei-Hyiaman D., Depetrillo M., Harvey-White J., et al. Cocaine- and amphetamine-related transcript peptide is involved in the orexigenic effect of endogenous anandamide. Neuroendocrinology 81 (2005) 273-282
-
(2005)
Neuroendocrinology
, vol.81
, pp. 273-282
-
-
Osei-Hyiaman, D.1
Depetrillo, M.2
Harvey-White, J.3
-
59
-
-
33845874637
-
Drug treatments for obesity: orlistat, sibutramine, and rimonabant
-
Padwal R.S., and Majumdar S.R. Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet 369 (2007) 71-77
-
(2007)
Lancet
, vol.369
, pp. 71-77
-
-
Padwal, R.S.1
Majumdar, S.R.2
-
60
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients. RIO-North America: a randomized controlled trial
-
The RIO-North American Study Group
-
The RIO-North American Study Group. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients. RIO-North America: a randomized controlled trial. JAMA 295 (2006) 761-775
-
(2006)
JAMA
, vol.295
, pp. 761-775
-
-
-
61
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
-
The RIO-Europe Study Group
-
The RIO-Europe Study Group. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365 (2005) 1389-1397
-
(2005)
Lancet
, vol.365
, pp. 1389-1397
-
-
-
62
-
-
27844463517
-
Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
-
The Rimonabant in Obesity-Lipids Study Group
-
The Rimonabant in Obesity-Lipids Study Group. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 353 (2005) 2121-2134
-
(2005)
N Engl J Med
, vol.353
, pp. 2121-2134
-
-
-
63
-
-
33845889549
-
Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes
-
Scheen A.J., et al. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes. Lancet 368 (2006) 1160-1172
-
(2006)
Lancet
, vol.368
, pp. 1160-1172
-
-
Scheen, A.J.1
-
64
-
-
41149130137
-
Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program
-
Van Gaal L., Pi-Sunyer X., Despres J.P., McCarthy C., and Scheen A. Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program. Diabetes Care 31 Suppl. 2 (2008) S229-S2240
-
(2008)
Diabetes Care
, vol.31
, Issue.SUPPL. 2
-
-
Van Gaal, L.1
Pi-Sunyer, X.2
Despres, J.P.3
McCarthy, C.4
Scheen, A.5
-
65
-
-
47649124651
-
-
FDA Briefing Document. NDA 21-888. Zimulti (rimonabant) Tablets, 20 mg. Sanofi Aventis. Advisory Committee; June 2007, Available at: http://www.fda.gov/ohrms/dockets/ac/07/briefing/2007-4306b1-fda-backgrounder.pdf[accessed September 8, 2007].
-
FDA Briefing Document. NDA 21-888. Zimulti (rimonabant) Tablets, 20 mg. Sanofi Aventis. Advisory Committee; June 2007, Available at: http://www.fda.gov/ohrms/dockets/ac/07/briefing/2007-4306b1-fda-backgrounder.pdf[accessed September 8, 2007].
-
-
-
-
66
-
-
47649096011
-
-
STRADIVARIUS (Strategy To Reduce Atherosclerosis Development InVolving Administration of Rimonabant-the Intravascular Ultrasound Study), Available at:http://www.clinicaltrials.gov/ct/show/NCT00124332?order=5 [accessed September 8, 2007].
-
STRADIVARIUS (Strategy To Reduce Atherosclerosis Development InVolving Administration of Rimonabant-the Intravascular Ultrasound Study), Available at:http://www.clinicaltrials.gov/ct/show/NCT00124332?order=5 [accessed September 8, 2007].
-
-
-
-
67
-
-
47649114133
-
-
CRESCENDO (Comprehensive Rimonabant Evaluation Study of Cardiovascular ENDpoints) and Outcomes, Available at: http://www.clinicaltrials.gov/ct/show/NCT00263042?order=2 [accessed September 8, 2007].
-
CRESCENDO (Comprehensive Rimonabant Evaluation Study of Cardiovascular ENDpoints) and Outcomes, Available at: http://www.clinicaltrials.gov/ct/show/NCT00263042?order=2 [accessed September 8, 2007].
-
-
-
-
68
-
-
41649090426
-
Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial
-
STRADIVARIUS Investigators
-
STRADIVARIUS Investigators. Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial. JAMA 299 (2008) 1547-1560
-
(2008)
JAMA
, vol.299
, pp. 1547-1560
-
-
|