-
1
-
-
0025253851
-
Biology of multifunctional cytokines: IL-6 and related molecules (IL 1 and TNF)
-
Akira, S., T. Hirano, T. Taga, and T. Kishimoto. 1990. Biology of multifunctional cytokines: IL-6 and related molecules (IL 1 and TNF). FASEB J 4:2860-2867.
-
(1990)
FASEB J
, vol.4
, pp. 2860-2867
-
-
Akira, S.1
Hirano, T.2
Taga, T.3
Kishimoto, T.4
-
2
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-kappa B in the immune system. Annu. Rev. Immunol. 12:141-179.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
3
-
-
0030010807
-
Modulation of inflammation and cytokine production by dietary (n-3) fatty acids
-
Blok, W. L., M. B. Katan, and J. van der Meer. 1996. Modulation of inflammation and cytokine production by dietary (n-3) fatty acids. J. Nutr. 126: 1515-1533.
-
(1996)
J. Nutr.
, vol.126
, pp. 1515-1533
-
-
Blok, W.L.1
Katan, M.B.2
Van Der Meer, J.3
-
4
-
-
0031417341
-
Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, Wy-14,643
-
Bojes, H. K., D. R. Germolec, P. Simeonova, A. Bruccoleri, R. Schoonhoven, M. I. Luster, and R. G. Thurman. 1997. Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, Wy-14,643. Carcinogenesis 18:669-674.
-
(1997)
Carcinogenesis
, vol.18
, pp. 669-674
-
-
Bojes, H.K.1
Germolec, D.R.2
Simeonova, P.3
Bruccoleri, A.4
Schoonhoven, R.5
Luster, M.I.6
Thurman, R.G.7
-
5
-
-
0031888958
-
PPAR gamma agonists inhibit production of monocyte inflammatory cytokines
-
Chengyu, J., A. T. Ting, and B. Seed. 1998. PPAR gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391:82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Chengyu, J.1
Ting, A.T.2
Seed, B.3
-
6
-
-
0032475922
-
Activation of proliferator-activated receptors alpha and gamma induces apoptosis in human monocyte-derived macrophages
-
Chinetti, G., S. Griglio, M. Antonucci, I. P. Torra, P. Delerive, Z. Majd, J.-C. Fruchart, J. Chapman, J. Najib, and B. Staels. 1998. Activation of proliferator-activated receptors alpha and gamma induces apoptosis in human monocyte-derived macrophages. J. Biol. Chem. 273:25573-25580.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25573-25580
-
-
Chinetti, G.1
Griglio, S.2
Antonucci, M.3
Torra, I.P.4
Delerive, P.5
Majd, Z.6
Fruchart, J.-C.7
Chapman, J.8
Najib, J.9
Staels, B.10
-
7
-
-
0029661982
-
The PPAR alpha-leukotriene B4 pathway to inflammation control
-
Devchand, P., H. Keller, J. Peters, M. Vazquez, F. Gonzalez, and W. Wahli. 1996. The PPAR alpha-leukotriene B4 pathway to inflammation control. Nature 384:39-43.
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.1
Keller, H.2
Peters, J.3
Vazquez, M.4
Gonzalez, F.5
Wahli, W.6
-
8
-
-
0023124097
-
Firefly luciferase gene: Structure and expression in mammalian cells mol
-
DeWet, J. R., K. V. Wood, M. DeLuca, D. R. Helinski, and S. Subramani. 1987. Firefly luciferase gene: structure and expression in mammalian cells Mol. Cell. Biol. 7:725-737.
-
(1987)
Cell. Biol.
, vol.7
, pp. 725-737
-
-
Dewet, J.R.1
Wood, K.V.2
Deluca, M.3
Helinski, D.R.4
Subramani, S.5
-
9
-
-
0026517010
-
Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
-
Dreyer, C., G. Krey, H. Keller, F. Givel, G. Helftenbein, and W. Wahli. 1992 Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68:879-887.
-
(1992)
Cell
, vol.68
, pp. 879-887
-
-
Dreyer, C.1
Krey, G.2
Keller, H.3
Givel, F.4
Helftenbein, G.5
Wahli, W.6
-
10
-
-
0028927444
-
Role for circulating lipoproteins in protection from endotoxin toxicity
-
Feingold, K., J. Funk, A. Moser, J. Shigenaga, J. Rapp, and C. Grunfeld. 1995. Role for circulating lipoproteins in protection from endotoxin toxicity. Infect. Immun. 63:2041-2046.
-
(1995)
Infect. Immun.
, vol.63
, pp. 2041-2046
-
-
Feingold, K.1
Funk, J.2
Moser, A.3
Shigenaga, J.4
Rapp, J.5
Grunfeld, C.6
-
11
-
-
0029847076
-
Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells
-
Gimble, J. M., C. E. Robinson, X. Wu, K. A. Kelly, B. R. Rodriguez, S. A. Kliewer, J. M. Lehmann, and D. C. Morris. 1996. Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells. Mol. Pharmacol. 50:1087-1094.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1087-1094
-
-
Gimble, J.M.1
Robinson, C.E.2
Wu, X.3
Kelly, K.A.4
Rodriguez, B.R.5
Kliewer, S.A.6
Lehmann, J.M.7
Morris, D.C.8
-
12
-
-
0029609755
-
PPAR: A mediator of peroxisome proliferator action
-
Green, S. 1995. PPAR: a mediator of peroxisome proliferator action. Mutat. Res. 333:101-109.
-
(1995)
Mutat. Res.
, vol.333
, pp. 101-109
-
-
Green, S.1
-
13
-
-
0028998129
-
Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III
-
Hertz, R., J. Bishara-Shieban, and J. Bar-Tana. 1995. Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III. J. Biol. Chem. 270:13470-13475.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13470-13475
-
-
Hertz, R.1
Bishara-Shieban, J.2
Bar-Tana, J.3
-
14
-
-
0028968521
-
Lipopolysaccharide regulation of lipoprotein lipase expresssion in murine macrophages
-
Hill, M., K. Kelly, X. Wu, F. Wanker, H. Bass, C. Morgan, C.-S. Wang, and J. Gimble. 1995. Lipopolysaccharide regulation of lipoprotein lipase expresssion in murine macrophages. Infect. Immun. 63:858-864.
-
(1995)
Infect. Immun.
, vol.63
, pp. 858-864
-
-
Hill, M.1
Kelly, K.2
Wu, X.3
Wanker, F.4
Bass, H.5
Morgan, C.6
Wang, C.-S.7
Gimble, J.8
-
15
-
-
0026768040
-
Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice
-
Hill, M., and R. McCallum. 1992. Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice. Infect. Immun. 60:4040-4050.
-
(1992)
Infect. Immun.
, vol.60
, pp. 4040-4050
-
-
Hill, M.1
McCallum, R.2
-
16
-
-
0030957958
-
Decreased expression of murine PPARγ in adipose tissue during endotoxemia
-
Hill, M. R., M. D. Young, C. M. McCurdy, and J. M. Gimble. 1997. Decreased expression of murine PPARγ in adipose tissue during endotoxemia. Endocrinology 138:3073-3076.
-
(1997)
Endocrinology
, vol.138
, pp. 3073-3076
-
-
Hill, M.R.1
Young, M.D.2
McCurdy, C.M.3
Gimble, J.M.4
-
17
-
-
0022457191
-
Interleukin-1: A regulatory role in glucocorticoid-regulated hepatic metabolism
-
Hill, M. R., R. D. Stith, and R. E. McCallum. 1986. Interleukin-1: a regulatory role in glucocorticoid-regulated hepatic metabolism. J. Immunol. 137: 858-862.
-
(1986)
J. Immunol.
, vol.137
, pp. 858-862
-
-
Hill, M.R.1
Stith, R.D.2
McCallum, R.E.3
-
18
-
-
0028972026
-
A prostaglandin j2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
Kliewer, S., J. M. Lenhard, T. M. Willson, I. Patel, D. C. Morris, and J. M. Lehmann. 1995. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83:813-819.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.1
Lenhard, J.M.2
Willson, T.M.3
Patel, I.4
Morris, D.C.5
Lehmann, J.M.6
-
19
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferator-actiated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators mol
-
Lee, S.S.-T., T. Pineau, J. Drago, E. Lee, J. Owens, D. Kroetz, P. Fernadez-Salguero, A. H. Westphal, and F. J. Gonzalez. 1995. Targeted disruption of the α isoform of the peroxisome proliferator-actiated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators Mol. Cell. Biol. 15:3012-3022.
-
(1995)
Cell. Biol.
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.-T.1
Pineau, T.2
Drago, J.3
Lee, E.4
Owens, J.5
Kroetz, D.6
Fernadez-Salguero, P.7
Westphal, A.H.8
Gonzalez, F.J.9
-
20
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR-gamma)
-
Lehmann, J., L. Moore, T. Smith-Oliver, W. Wilkison, and S. K. T. Willson. 1995. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR-gamma). J. Biol. Chem. 270:12953-12956.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.1
Moore, L.2
Smith-Oliver, T.3
Wilkison, W.4
Willson, S.K.T.5
-
21
-
-
0030060358
-
Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm
-
Lemberger, T., R. Saladin, M. Vazquez, F. Assimacopoulos, B. Staels, B. Desvergne, W. Wahli, and J. Auwerx. 1996. Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm. J. Biol. Chem. 271:1764-1769.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1764-1769
-
-
Lemberger, T.1
Saladin, R.2
Vazquez, M.3
Assimacopoulos, F.4
Staels, B.5
Desvergne, B.6
Wahli, W.7
Auwerx, J.8
-
22
-
-
0026597950
-
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid
-
Mangelsdorf, D. J., U. Borgmeyer, R. A. Heyman, J. Y. Zhou, E. S. Ong, A. E. Oro, A. Kakizuka, and R. M. Evans. 1992. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev. 6:329-344.
-
(1992)
Genes Dev.
, vol.6
, pp. 329-344
-
-
Mangelsdorf, D.J.1
Borgmeyer, U.2
Heyman, R.A.3
Zhou, J.Y.4
Ong, E.S.5
Oro, A.E.6
Kakizuka, A.7
Evans, R.M.8
-
23
-
-
0026730908
-
The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid ω-hydroxylase, by clofibric acid
-
Muerhoff, A. S., K. J. Griffen, and E. F. Johnson. 1992. The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid ω-hydroxylase, by clofibric acid. J. Biol. Chem. 267: 19051-19053.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19051-19053
-
-
Muerhoff, A.S.1
Griffen, K.J.2
Johnson, E.F.3
-
24
-
-
0031418657
-
Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
-
Peters, J. M., R. C. Cattley, and F. J. Gonzalez. 1997. Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis 18:2029-2033.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2029-2033
-
-
Peters, J.M.1
Cattley, R.C.2
Gonzalez, F.J.3
-
25
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice
-
Peters, J. M., N. Hennuyer, B. Staels, J. Fruchart, C. Fievet, F. Gonzalez, and J. Auwerx. 1997. Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice. J. Biol. Chem. 272:27307-27312.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
Fruchart, J.4
Fievet, C.5
Gonzalez, F.6
Auwerx, J.7
-
26
-
-
0029005323
-
Triglyceride-rich lipoproteins prevent septic death in rats
-
Read, T., C. Grunfeld, Z. Kumwenda, M. Calhoun, J. Kane, K. Feingold, and J. Rapp. 1995. Triglyceride-rich lipoproteins prevent septic death in rats. J. Exp. Med. 182:267-272.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 267-272
-
-
Read, T.1
Grunfeld, C.2
Kumwenda, Z.3
Calhoun, M.4
Kane, J.5
Feingold, K.6
Rapp, J.7
-
27
-
-
33745158157
-
A simple method for estimating 50% end points
-
Reed, L. J., and H. A. Muench. 1938. A simple method for estimating 50% end points. Am. J. Hyg. 27:493-499.
-
(1938)
Am. J. Hyg.
, vol.27
, pp. 493-499
-
-
Reed, L.J.1
Muench, A.H.A.2
-
28
-
-
0031886864
-
The peroxisome proliferator-activated receptor gamma is a negative regulator of macrophage activation
-
Ricote, M., A. C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass. 1998. The peroxisome proliferator-activated receptor gamma is a negative regulator of macrophage activation. Nature 391:79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
29
-
-
0032571076
-
DNA bending is induced by binding of the peroxisome proliferator-activated receptor gamma2 heterodimer to its response element in the murine lipoprotein lipase promoter
-
Robinson, C. E., X. Wu, D. C. Morris, and J. M. Gimble. 1998. DNA bending is induced by binding of the peroxisome proliferator-activated receptor gamma2 heterodimer to its response element in the murine lipoprotein lipase promoter. Biochem. Biophys. Res. Commun. 244:671-677.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.244
, pp. 671-677
-
-
Robinson, C.E.1
Wu, X.2
Morris, D.C.3
Gimble, J.M.4
-
30
-
-
0031419250
-
Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators
-
Rose, M. L., D. R. Germolec, R. Schoonhoven, and R. G. Thurman. 1997. Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators. Carcinogenesis 18:1453-1456.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1453-1456
-
-
Rose, M.L.1
Germolec, D.R.2
Schoonhoven, R.3
Thurman, R.G.4
-
31
-
-
0031878489
-
Wy-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes
-
Rusyn, I., H. Tsukamoto, and R. G. Thurman. 1998. Wy-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes. Carcinogenesis 19:1217-1222.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1217-1222
-
-
Rusyn, I.1
Tsukamoto, H.2
Thurman, R.G.3
-
32
-
-
0030602866
-
The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation
-
Schoonjans, K., B. Staels, and J. Auwerx. 1996. The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochim. Biophys. Acta 1302:93-109.
-
(1996)
Biochim. Biophys. Acta
, vol.1302
, pp. 93-109
-
-
Schoonjans, K.1
Staels, B.2
Auwerx, J.3
-
33
-
-
0029791412
-
PPAR alpha and PPAR gamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans, K., J. Peinado-Onsurbe, R. Heyman, M. Briggs, D. Caayet, S. Deeb, B. Staels, and J. Auwerx. 1996. PPAR alpha and PPAR gamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J. 15:5336-5348.
-
(1996)
EMBO J.
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Heyman, R.3
Briggs, M.4
Caayet, D.5
Deeb, S.6
Staels, B.7
Auwerx, J.8
-
34
-
-
0030176037
-
Effects of hypolipidemic drugs on the expression of genes involved in high density lipoprotein metabolism in the rat
-
Staels, B., A. V. Tol, J.-C. Fruchart, and J. Auwerx. 1996. Effects of hypolipidemic drugs on the expression of genes involved in high density lipoprotein metabolism in the rat. Isr. J. Med. Sci. 32:490-498.
-
(1996)
Isr. J. Med. Sci.
, vol.32
, pp. 490-498
-
-
Staels, B.1
Tol, A.V.2
Fruchart, J.-C.3
Auwerx, J.4
-
35
-
-
0028131951
-
Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells
-
Steineger, H., H. Sorensen, J. Tugwood, S. Skrede, O. Spydevold, and K. Gautvik. 1994. Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells. Eur. J. Biochem. 225:967-974.
-
(1994)
Eur. J. Biochem.
, vol.225
, pp. 967-974
-
-
Steineger, H.1
Sorensen, H.2
Tugwood, J.3
Skrede, S.4
Spydevold, O.5
Gautvik, K.6
-
36
-
-
0028988487
-
PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
-
Tontonoz, P., E. Hu, J. Devine, E. G. Beale, and B. M. Spiegelman. 1995. PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol. Cell. Biol. 15:351-357.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 351-357
-
-
Tontonoz, P.1
Hu, E.2
Devine, J.3
Beale, E.G.4
Spiegelman, B.M.5
-
37
-
-
0023028369
-
Shock and tissue injury induced by recombinant human cachectin
-
Tracey, K., B. Beutler, S. Lowry, J. Merry-weather, S. Wolpe, I. Milsark, R. Hariri, T. Fahey III, A. Zentella, J. Albert, T. Shires, and A. Cerami. 1986. Shock and tissue injury induced by recombinant human cachectin. Science 234:470-474.
-
(1986)
Science
, vol.234
, pp. 470-474
-
-
Tracey, K.1
Beutler, B.2
Lowry, S.3
Merry-Weather, J.4
Wolpe, S.5
Milsark, I.6
Hariri, R.7
Fahey T. III8
Zentella, A.9
Albert, J.10
Shires, T.11
Cerami, A.12
-
38
-
-
0029866253
-
Antagonistic effects of dietary arachidonic acid and n-3 polyunsaturated fatty acids
-
Whelan, J. 1996. Antagonistic effects of dietary arachidonic acid and n-3 polyunsaturated fatty acids. J. Nutr. 126:10868-10915.
-
(1996)
J. Nutr.
, vol.126
, pp. 10868-10915
-
-
Whelan, J.1
-
39
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
Yu, K., W. Bayona, C. B. Kallen, H. P. Harding, C. P. Ravera, G. McMahon, M. Brown, and M. A. Lazar. 1995. Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J. Biol. Chem. 270:23975-23983.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
Harding, H.P.4
Ravera, C.P.5
McMahon, G.6
Brown, M.7
Lazar, M.A.8
-
40
-
-
0026756096
-
Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase
-
Zhang, B., L. L. Marcus, F. G. Sajadi, K. Alvares, J. K. Reddy, S. Subramani, R. A. Rachubinski, and J. P. Capone. 1992. Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. Proc. Natl. Acad. Sci. USA 89:7541-7545.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7541-7545
-
-
Zhang, B.1
Marcus, L.L.2
Sajadi, F.G.3
Alvares, K.4
Reddy, J.K.5
Subramani, S.6
Rachubinski, R.A.7
Capone, J.P.8
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